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Original Article04-12-1998
Glycosylated hemoglobin levels and cardiac abnormalities in fetuses of diabetic mothers
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(5):237-243
Views94This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleGlycosylated hemoglobin levels and cardiac abnormalities in fetuses of diabetic mothers
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(5):237-243
DOI 10.1590/S0100-72031998000500002
Views94We analyze prospectively the existence of a relationship between the mother’s glycemic control, in the first half of pregnancy, and the occurrence of abnormal fetal cardiac abnormalities, in pregnant women with diabetes mellitus. In 127 pregnant women, the level of glycosylated hemoglobin was determined on the first visit during prenatal care. Nine patients had type I diabetes, 77 type II and 41 gestational diabetes mellitus (GDM). All mothers were submitted to detailed fetal echocardiography, during the 28th ± 4.127 week of gestation. In 31 (24.4%) of the 127 fetuses cardiac anomalies were detected. In 10 (7.87%) an isolated cardiac anomaly was identified. Mean HbA1c in the group of pregnant women without cardiac anomalies (5.64%) was statistically different from the group with anomalies (10.14%) (p<0.0001). The receiver-operator characteristic, representing the balance between sensitivity (92.83%) and specificity (98.92%) in the diagnosis of structural cardiac abnormalities, showed a cut-off point at the 7.5% HbA1c level. In nine of ten fetuses with structural cardiac anomalies, the maternal level of HbA1c was higher than 7.5%. The difference between means of the groups with and without myocardial hypertrophy diagnosed as isolated anomaly (MCHP) was not statistically significant, when considering both type II diabetes and GDM subgroups. In conclusion, levels of HbA1c higher than 7.5% were associated with most cases of echocardiographycally diagnosed structural cardiac anomalies. On the other hand, this test was not useful to discriminate conceptus with MCHP.
Key-words Diabetes mellitusFetusGlysosylated hemoglobin AMalformationsPregnancy complicationsUltrasonographySee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
04-12-1998
RBGO: presente e futuro
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(5):235-235
Abstract
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
04-12-1998
Estudo longitudinal das alterações hemodinâmicas e estruturas cardíacas em gestantes sem patologia
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):225-225
Views71This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Estudo longitudinal das alterações hemodinâmicas e estruturas cardíacas em gestantes sem patologia
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):225-225
DOI 10.1590/S0100-72031998000400009
Views71Estudo Longitudinal das Alterações Hemodinâmicas e Estruturas Cardíacas em Gestantes sem Patologia[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
04-12-1998
Ultra-sonometria de calcâneo em mulheres pré e pós-menopáusicas comparação com densitometria óssea
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):225-225
Abstract
Ultra-sonometria de calcâneo em mulheres pré e pós-menopáusicas comparação com densitometria óssea
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):225-225
DOI 10.1590/S0100-72031998000400010
Views97Ultra-Sonometria de Calcâneo em Mulheres Pré e Pós-Menopáusicas Comparação com Densitometria Óssea […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Case Report04-12-1998
Necrotizing fasciitis of the breast: case report
- Marco Aurélio da Costa Silva,
- Jales Benevides Santana Filho,
- Ruffo de Freitas Júnior,
- Edgar Berquó Peleja,
- Rossana de Araújo Catão, [ … ],
- Luiz Fernando Jubé Ribeiro
Views140This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Case ReportNecrotizing fasciitis of the breast: case report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):221-224
DOI 10.1590/S0100-72031998000400008
- Marco Aurélio da Costa Silva,
- Jales Benevides Santana Filho,
- Ruffo de Freitas Júnior,
- Edgar Berquó Peleja,
- Rossana de Araújo Catão,
- Luiz Fernando Jubé Ribeiro
Views140See moreA case of postsurgical necrotizing fasciitis is presented. A 68-year-old female patient was submitted to a lumpectomy for a big breast lipoma. After surgen there was an aggressive local infection, with extensive necrosis of the breast tissue, including the superficial and deep fasciae and also the skin over the breast. The gravity of the disease and the difficulties in its diagnosis due to the late skin necrosis are emphasized. Under such circunstances an early and aggressive approach is necessary.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Case Report04-12-1998
Leiomyoma of the female urethra: a case report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):217-219
Abstract
Case ReportLeiomyoma of the female urethra: a case report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):217-219
DOI 10.1590/S0100-72031998000400007
Views108See moreA case of urethral leiomyoma – a mass of approximately 5 cm in diameter – located on the anterior wall of the vaginal lower third is reported. The patient was submitted to a surgical tumor excision. Histopathological and immunohistochemical studies indicated leiomyoma, which is always a benign, unusual neoplasm, rarely relapsing after excision. Its pathogenesis and clinical features are also focused on.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article04-12-1998
Fine-needle aspiration cytology (FNAC) in the differential diagnosis of breast pathology
- Francisco José Candido dos Reis,
- Jurandyr Moreira de Andrade,
- Maria Angeles Sanches Llorach Velludo,
- Sérgio Alexandre de Oliveira,
- Ricardo Barbelli Feitosa, [ … ],
- Sérgio Bighetti
Views178This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleFine-needle aspiration cytology (FNAC) in the differential diagnosis of breast pathology
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):209-213
DOI 10.1590/S0100-72031998000400006
- Francisco José Candido dos Reis,
- Jurandyr Moreira de Andrade,
- Maria Angeles Sanches Llorach Velludo,
- Sérgio Alexandre de Oliveira,
- Ricardo Barbelli Feitosa,
- Heitor Ricardo Cosiski Marana,
- Sérgio Bighetti
Views178See moreFine-needle aspiration cytology (FNAC) is a simple method and free from complications, among great value in mastology. Its accuracy can suffer the influence of several factors, among which we can highlight the experience of the physician who performs it. With the objective of verifying the effectiveness of FNAC performed by general gynecologists, 341 patients were studied concerning the relationship between the results of FNAC and the histology of the breast lesion. We obtained sensitivity of 70.87%, specificity of 70.58%, predictive positive value of 92.40%, predictive negative value of 89.36% and accuracy of 70.67%. We concluded that FNAC is of great value in handling breast lesions and can be appropriately performed by general gynecologists. The method, however, may lead to errors of diagnosis. We do not recommend, therefore, the use of the result of FNAC as a definitive diagnosis; instead this result must be interpreted in the context of the clinical diagnosis and mammography.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article04-12-1998
Post-tubal sterilization syndrome: evaluation of the psychological and clinical disturbances in tubal ligation syndrome
- Rogério Dias,
- Eliana Aguiar Petri Nahás,
- Olívia Maria Rogenski,
- Laurival A. De Luca,
- Francesco A. Viscomi, [ … ],
- Reginaldo G. C. Lopes
Views102This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePost-tubal sterilization syndrome: evaluation of the psychological and clinical disturbances in tubal ligation syndrome
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(4):199-205
DOI 10.1590/S0100-72031998000400005
- Rogério Dias,
- Eliana Aguiar Petri Nahás,
- Olívia Maria Rogenski,
- Laurival A. De Luca,
- Francesco A. Viscomi,
- Reginaldo G. C. Lopes
Views102The purpose of the present study was to investigate the menstrual disturbances and the psychological effects of post-tubal sterilization – the so-called post-tubal sterilization syndrome. Does it exist? The authors followed-up prospectively 300 women from the Gynecological Endoscopy and Family Planning Section, Department of Obstetrics and Gynecology, Botucatu Medical School, Universidade Estadual Paulista (UNESP) during one, three and five years after tubal sterilization surgery. Different parameters such as menstrual cycle length, duration of menstrual flow, dysmenorrhea, pelvic pain, regret rates etc, after tubal ligation, were analyzed. Each woman served as her own control. In conclusion, our findings suggest that most women reported no menstrual changes subsequent to sterilization. These findings do not deny or diminish the importance or benefits of tubal sterilization, but serve as a focus for further investigation.
Key-words Family planningMenstrual disturbancesPost-tubal sterilization syndromeTubal ligation syndromeSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article07-20-2004
Search for human papillomavirus in samples of normal endometrial tissue and tissue with carcinoma by the PCR technique
- Edison Natal Fedrizzi,
- Newton Sérgio de Carvalho,
- Luisa Lina Villa,
- Irene Vieira de Souza,
- Ana Paula Martins Sebastião
Views126259This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleSearch for human papillomavirus in samples of normal endometrial tissue and tissue with carcinoma by the PCR technique
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(4):277-287
DOI 10.1590/S0100-72032004000400003
- Edison Natal Fedrizzi,
- Newton Sérgio de Carvalho,
- Luisa Lina Villa,
- Irene Vieira de Souza,
- Ana Paula Martins Sebastião
Views126259See moreOBJECTIVE: to compare the prevalence of DNA of human papillomavirus (HPV), in samples of normal endometrial tissue, and tissue with endometrial carcinoma of women submitted to surgical treatment (hysterectomy), or between endometrial carcinoma and benign disease, through the PCR technique. METHODS: this is an observational control-case study where 100 women (50 with endometrial carcinoma and 50 with normal endometrial tissue) were analyzed for the detection of HPV DNA in samples of endometrial tissue kept in paraffin blocks by the PCR technique. The cases of endometrial carcinoma with uncertain primary site of the lesion as well as the cases with previous or current history of pre-neoplasic lesions or carcinoma of the lower genital tract were excluded. Variables as age, smoking habit, endometrial trophism, squamous differentiation and degree of tumor differentiation were also evaluated. RESULTS: the estimated relative risk of the presence of HPV in the endometrial carcinoma and in the normal endometrial tissue was the same. HPV was detected in 8% of the cases of carcinoma and 10% in the normal endometrial tissue. In spite of HPV having been 3.5 times more detected in women with smoking habit in the group without carcinoma, there was no statistical difference. The presence of HPV was also not correlated with the women’s age, endometrial trophism, squamous differentiation and degree of tumor differentiation. The HPV types 16 (5 cases) and 18 (4 cases) were the viruses most frequently found both in the normal endometrial tissue or in the tissue with carcinoma. No oncogenic low risk virus was detected in the samples. CONCLUSION: The same proportion of HPV is present in the endometrial tissue of women with endometrial cancer and with normal endometrium. It could not be demonstrated a possible correlation of DNA of HPV with the development of endometrial carcinoma.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
FEBRASGO POSITION STATEMENT04-25-2024
Hyperprolactinemia in women: treatment
- Cristina Laguna Benetti-Pinto
,
- Andrea Prestes Nácul
,
- Ana Carolina Japur Rosa e Silva
,
- Gustavo Arantes Rosa Maciel
,
- Vania dos Santos Nunes Nogueira
,
[ … ], - Andrea Glezer
Views1226This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
FEBRASGO POSITION STATEMENTHyperprolactinemia in women: treatment
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS05
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Cristina Laguna Benetti-Pinto
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FEBRASGO POSITION STATEMENT04-25-2024
Hyperprolactinemia in women: diagnostic approach
- Andrea Glezer
,
- Heraldo Mendes Garmes
,
- Leandro Kasuki
,
- Manoel Martins
,
- Paula Condé Lamparelli Elias
,
[ … ], - Andrea Prestes Nácul
Views1225This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
FEBRASGO POSITION STATEMENTHyperprolactinemia in women: diagnostic approach
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS04
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Andrea Glezer
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FEBRASGO POSITION STATEMENT00-00-2024
Breech birth care: Number 1 – 2024
- Álvaro Luiz Lage Alves
,
- Alexandre Massao Nozaki
,
- Carla Betina Andreucci Polido
,
- Lucas Barbosa da Silva
,
- Roxana Knobel
Views1028This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
FEBRASGO POSITION STATEMENTBreech birth care: Number 1 – 2024
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgofps1
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Álvaro Luiz Lage Alves
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Letter to the Editor04-09-2024
Letter to Editor: In response to existence of SARS-CoV-2 in the peritoneal fluid
- Gustavo Romero-Velez
,
- Guillermo Ponce de Leon-Ballesteros
,
- Juan Barajas-Gamboa
,
- Jerry Dang
,
- Andrew Strong
,
[ … ], - Mathew Kroh
Abstract
Letter to the EditorLetter to Editor: In response to existence of SARS-CoV-2 in the peritoneal fluid
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo24
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Gustavo Romero-Velez
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FEBRASGO POSITION STATEMENT04-02-2024
Use of hormones and risk of venous thromboembolism
- Venina Isabel Poço Viana Leme de Barros
,
- André Luiz Malavasi Longo de Oliveira
,
- Denis Jose do Nascimento
,
- Eduardo Zlotnik
,
- Marcelo Melzer Teruchkin
,
[ … ], - Paulo Francisco Ramos Margarido
Views862This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
FEBRASGO POSITION STATEMENTUse of hormones and risk of venous thromboembolism
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS02
- Venina Isabel Poço Viana Leme de Barros
,
- André Luiz Malavasi Longo de Oliveira
,
- Denis Jose do Nascimento
,
- Eduardo Zlotnik
,
- Marcelo Melzer Teruchkin
,
- Marcos Arêas Marques
,
- Paulo Francisco Ramos Margarido
Views862See moreKey points
•The risk of venous thromboembolism (VTE) is not increased in women using long-acting reversible contraceptive methods (LARCs) with progestogens.
•Oral contraceptives with levonorgestrel or norgestimate confer half the risk of VTE compared to oral contraceptives containing desogestrel, gestodene or drospirenone.
•Progestogen-only pills do not confer an increased risk of VTE.
•Women using transdermal contraceptive patches and combined oral contraceptives (COCs) are at an approximately eight times greater risk of VTE than non-users of hormonal contraceptives (HCs), corresponding to 9.7 events per 10,000 women/years.
•Vaginal rings increase the risk of VTE by 6.5 times compared to not using HC, corresponding to 7.8 events per 10,000 women/years.
•Several studies have demonstrated an increased risk of VTE in transgender individuals receiving hormone therapy (HT).
•Hormone therapy during menopause increases the risk of VTE by approximately two times, and this risk is increased by obesity, thrombophilia, age over 60 years, surgery and immobilization.
•The route of estrogen administration, the dosage and type of progestogen associated with estrogen may affect the risk of VTE in the climacteric.
•Combined estrogen-progesterone therapy increases the risk of VTE compared to estrogen monotherapy.
•Postmenopausal HT increases the risk of thrombosis at atypical sites.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Venina Isabel Poço Viana Leme de Barros
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Editorial00-00-2024
The path to elimination: FEBRASGO 2023’s targeted strategies against cervical cancer in Brazil
- Agnaldo Lopes da Silva Filho
,
- Cecilia Maria Roteli-Martins
,
- Neila Maria de Góis Speck
,
- Newton Sérgio de Carvalho
,
- Eduardo Batista Cândido
,
[ … ], - Júlio César Teixeira
Views836This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
EditorialThe path to elimination: FEBRASGO 2023’s targeted strategies against cervical cancer in Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgoedt2
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Agnaldo Lopes da Silva Filho
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FEBRASGO POSITION STATEMENT04-02-2024
Vulvovaginitis in pregnant women
- Geraldo Duarte
,
- Iara Moreno Linhares
,
- Regis Kreitchmann
,
- Andréa da Rocha Tristão
,
- Evelyn Traina
,
[ … ], - Joelma Queiroz Andrade
Views829This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
FEBRASGO POSITION STATEMENTVulvovaginitis in pregnant women
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS03
- Geraldo Duarte
,
- Iara Moreno Linhares
,
- Regis Kreitchmann
,
- Andréa da Rocha Tristão
,
- Evelyn Traina
,
- Ivete Canti
,
- Marcos Takimura
,
- Joelma Queiroz Andrade
Views829See moreKey points
• The balanced vaginal microbiome is the main factor defending the vaginal environment against infections. Lactobacilli play a key role in this regard, maintaining the vaginal pH within the normal range (3.8 to 4.5).
•Hormonal and immune adaptations resulting from pregnancy influence changes in the vaginal microbiome during pregnancy.
•An altered vaginal microbiome predisposes to human immunodeficiency virus (HIV) infection.
•Bacterial vaginosis is the main clinical expression of an imbalanced vaginal microbiome.
•Vulvovaginal candidiasis depends more on the host’s conditions than on the etiological agent.
•Trichomonas vaginalis is a protozoan transmitted during sexual intercourse.
•The use of probiotics is not approved for use in pregnant women.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Geraldo Duarte
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Original Article07-01-2015
Prevalence of congenital abnormalities identified in fetuses with 13, 18 and 21 chromosomal trisomy
- Caroline Soares Cristofari Emer,
- Julio Alejandro Peña Duque,
- Ana Lúcia Letti Müller,
- Rejane Gus,
- Maria Teresa Vieira Sanseverino, [ … ],
- José Antonio de Azevedo Magalhães
Views212This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePrevalence of congenital abnormalities identified in fetuses with 13, 18 and 21 chromosomal trisomy
Revista Brasileira de Ginecologia e Obstetrícia. 2015;37(7):333-338
DOI 10.1590/S0100-720320150005373
- Caroline Soares Cristofari Emer,
- Julio Alejandro Peña Duque,
- Ana Lúcia Letti Müller,
- Rejane Gus,
- Maria Teresa Vieira Sanseverino,
- André Anjos da Silva,
- José Antonio de Azevedo Magalhães
Views212See morePURPOSE:
To describe the prevalence of malformations found in fetuses with trisomy of chromosomes 13, 18 and 21 by identifying the most frequent within each condition.
METHODS:
A retrospective cross-sectional study with the analysis of trisomy cases of chromosomes 13, 18 and 21 diagnosed through fetal karyotype obtained by amniocentesis/cordocentesis, between October 1994 and May 2014, at a Teaching Hospital in Brazil Southern Region. Malformations identified through morphological ultrasonography were described and, subsequently, confirmed in newborn examinations and/or fetal autopsy. The results were analyzed using Fisher’s test and analysis of variance (ANOVA), with a 5% level of significance (p=0.05).
RESULTS:
Sixty-nine cases of trisomy were diagnosed among 840 exams; nine were excluded due to outcome outside Hospital de Clínicas de Porto Alegre or incomplete records, remaining 60 cases (nine cases of chromosome 13 trisomy, 26 of chromosome 18, and 25 of chromosome 21). In all three groups, heart disease occurred in most cases; the ventricular septal defect was more prevalent and occurred in 66.7% of the trisomy 13 group. Gastrointestinal abnormalities were more prevalent in the trisomy 18 group, especially omphalocele (38.5%; p<0.01). Genitourinary anomalies were more significantly frequent in the trisomy 13 group (pyelectasis, 55.6% - p<0.01; ambiguous genitalia, 33.3% - p=0.01). Central nervous system defects were identified in all cases of trisomy 13. Facial cracks were significantly more prevalent among fetuses with trisomy 13 (66.7%; p<0.01). Hand and feet malformations significantly differed among the trisomy groups. Hand defects occurred in 50% of trisomy 18 cases, and in 44.4% of all trisomy 13 cases (p<0.01); congenital clubfoot was more common in the trisomy 18 group, being detected in 46.2% of fetuses (p<0.01). The abnormalities were found in 50.9, 27.3 and 21.7% of trisomy 18, 13 and 21 cases respectively.
CONCLUSION:
Many fetal malformations identified at ultrasound are suggestive of trisomy and represent an important tool for etiologic diagnosis and prenatal and pre-conception genetic counseling.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article04-15-2019
Isthmocele: From Risk Factors to Management
- Piergiorgio Iannone
,
- Giulia Nencini,
- Gloria Bonaccorsi,
- Ruby Martinello,
- Giovanni Pontrelli, [ … ],
- Gennaro Scutiero
Views289This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleIsthmocele: From Risk Factors to Management
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(1):44-52
- Piergiorgio Iannone
,
- Giulia Nencini,
- Gloria Bonaccorsi,
- Ruby Martinello,
- Giovanni Pontrelli,
- Marco Scioscia,
- Luigi Nappi,
- Pantaleo Greco,
- Gennaro Scutiero
Views289See moreAbstract
Objective
The aim of the present study was to perform a comprehensive review of the literature to provide a complete and clear picture of isthmocele-a hypoechoic area within themyometriumat the site of the uterine scar of a previous cesarean section-by exploring in depth every aspect of this condition.
Methods
A comprehensive review of the literature was performed to identify the most relevant studies about this topic.
Results
Every aspect of isthmocele has been studied and described: pathophysiology, clinical symptoms, classification, and diagnosis. Its treatment, both medical and surgical, has also been reported according to the actual literature data.
Conclusion
Cesarean section is the most common surgical procedure performed worldwide, and one of the consequences of this technique is isthmocele. A single and systematic classification of isthmocele is needed to improve its diagnosis and management. Further studies should be performed to better understand its pathogenesis.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Piergiorgio Iannone
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Original Article05-16-2019
Variables Associated with Endometriosis-related Pain: A Pilot Study using a Visual Analogue Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(3):170-175
Views183This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleVariables Associated with Endometriosis-related Pain: A Pilot Study using a Visual Analogue Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(3):170-175
Views183See moreAbstract
Objective
Endometriosis is a complex disease, and pain is an important component of the syndrome. One of the most used methods to assess pain is the visual analogue scale (VAS). The aim of the present research was to study the pain experienced by patients who referred to our unit for endometriosis, using the VAS to understand the variables that could influence it.
Methods
We have conducted a prospective study from February 2012 to December 2016, enrolling 388 patients who referred to a university hospital, in Florence, Italy. We have included in the present study patients during their follow-up for endometriosis; we have also included patients who underwent surgery with a histological diagnosis of endometriosis. We have collected sociodemographic and clinical information regarding age, body mass index (BMI), smoking habit, number of pregnancies, and endometriosis staging. Finally, we have administered the VAS for several symptoms.
Results
Dysmenorrhea was the symptom associated with the highest perception of pain (mean VAS score of 5.76). The logistic regression showed that the stage of endometriosis could influence the pain associated to constipation and to dysuria. The linear regression showed that age couldinfluencethe pain associated to constipation, to dyspareunia,and to dysmenorrhea. A positive correlation was found between dysmenorrhea and chronic pelvic pain(CPP), between dysmenorrhea and dyspareunia, and between constipation and dysuria.
Conclusion
Using a validated method, the VAS, we have studied the pain experienced by a group of patients with a history of endometriosis and observed that smoking habit and BMI did not influence the VAS scores, and that dysmenorrhea was associated with the highest perception of pain.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article11-01-2018
Do Food Intake and Food Cravings Change during the Menstrual Cycle of Young Women?
- Luciana Bronzi de Souza,
- Karine Anusca Martins,
- Mariana Morais Cordeiro,
- Ymárdila de Souza Rodrigues,
- Bruna Paola Murino Rafacho, [ … ],
- Rafael Aiello Bomfim
Views399This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleDo Food Intake and Food Cravings Change during the Menstrual Cycle of Young Women?
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(11):686-692
- Luciana Bronzi de Souza,
- Karine Anusca Martins,
- Mariana Morais Cordeiro,
- Ymárdila de Souza Rodrigues,
- Bruna Paola Murino Rafacho,
- Rafael Aiello Bomfim
Views399Abstract
Objective
The aim of the present study was to assess the anthropometric measures, food intake and food cravings during the menstrual cycle of undergraduate students of the faculty of nutrition.
Methods
A cross-sectional study was performed with 27 students from a public university in the state of Mato Grosso do Sul, Brazil, who had their food intake evaluated through a 24-hour food recall, their nutritional status evaluated based on anthropometric measures, and food cravings evaluated using the Food Desire Questionnaire. Data were collected during an evaluation in the follicular phase (between the 5th and the 9th day of the menstrual cycle) and another in the luteal phase (LP) (between the 20th and the 25th day of the menstrual cycle). For food intake variables, the analysis of variance (ANOVA) test was used, followed by the Tukey test. The Mann-Whitney test was used for the analysis of food cravings, considering a significance level of 5% (p< 0.05).
Results
The desire for foods rich in sugar, salt, and fat, such as chocolate, pastries, snacks and desserts were higher (p< 0.05) during the premenstrual period, although it did not reflect neither a higher energy intake nor an alteration in the distribution of macronutrients. A higher intake of carbohydrates, proteins, fibers, and calcium was observed during the LP; however, without statistical difference between the groups. There were no differences either in the intake of any food group or in the anthropometric measurements (p> 0.05).
Conclusion
Food cravings of nutrition students differed between the phases of the menstrual cycle; however, with no difference in food intake and in anthropometric measures.
Key-words Feeding behaviorfollicular phasefood intakeluteal phaseMenstrual cycleNutrition assessmentSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article04-17-2020
Quality of Life in Women with Deep Endometriosis: A Cross-Sectional Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(2):90-95
Views226This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleQuality of Life in Women with Deep Endometriosis: A Cross-Sectional Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(2):90-95
Views226See moreAbstract
Objective
To describe clinical and sociodemographic characteristics of women with deep infiltrating endometriosis (DIE) and assess their quality of life (QOL) during 6 months of medical treatment.
Methods
A descriptive cross-sectional study of 60 women diagnosed with DIE either by surgery or image methods (ultrasound or magnetic resonance), who received clinical treatment for at least 6 months in the Universidade de Campinas, Campinas, state of São Paulo, Brazil. Both the SF-36 and the EHP-30 questionnaires were used to assess the quality of life.
Results
The mean age of the patients was 37.7 ± 6.0 years old, with 50% presenting dysmenorrhea; 57% dyspareunia; and 50% chronic pelvic pain. The SF-36 and the EHP-30 revealed impaired quality of life. In the SF-36, the worst domains were limitation due to emotional aspects (40.2 ± 43.1) and self-esteem and disposition (46.1 ± 24.8), whereas in the EHP-30 they were social well-being (50.3 ± 30.6); infertility (48.0 ± 36.3); and sexual intercourse (54.0 ± 32.1).
Conclusion
Although clinically treated, women with deep endometriosis present impairment in different domains of quality of life regardless of the questionnaire used for evaluation.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article09-30-2019
Pharmacological Treatment for Symptomatic Adenomyosis: A Systematic Review
- Cristina Laguna Benetti-Pinto
,
- Ticiana Aparecida Alves de Mira,
- Daniela Angerame Yela,
- Cassia Raquel Teatin-Juliato,
- Luiz Gustavo Oliveira Brito
Views232This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticlePharmacological Treatment for Symptomatic Adenomyosis: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(9):564-574
- Cristina Laguna Benetti-Pinto
,
- Ticiana Aparecida Alves de Mira,
- Daniela Angerame Yela,
- Cassia Raquel Teatin-Juliato,
- Luiz Gustavo Oliveira Brito
Views232See moreAbstract
Objective
To assess the efficacy of non-surgical treatment for adenomyosis.
Data Sources
A search was performed by two authors in the Pubmed, Scopus, and Scielo databases and in the grey literature from inception to March 2018, with no language restriction.
Selection of Studies
We have included prospective randomized studies for treating symptomaticwomen with adenomyosis (abnormal uterine bleeding and/or pelvic pain) diagnosed by ultrasound or magnetic resonance imaging.
Data Collection
Studies were primarily selected by title and abstract. The articles that were eligible for inclusion were evaluated in their entirety, and their data was extracted for further processing and analysis.
Data Synthesis
From567retrieved records only 5 remained for analysis. The intervention groups were: levonorgestrel intrauterine system (LNG-IUS)(n= 2), dienogest (n= 2), and letrozole (n= 1). Levonorgestrel intrauterine system was effective to control bleeding when compared to hysterectomy or combined oral contraceptives (COCs). One study assessed chronic pelvic pain and reported that LNG-IUS was superior to COC to reduce symptoms. Regarding dienogest, it was efficient to reduce pelvic pain when compared to placebo or goserelin, but less effective to control bleeding than gonadotropin-releasing hormone (GnRH) analog. Letrozolewas as efficient asGnRHanalog to relieve dysmenorrhea and dyspareunia, but not for chronic pelvic pain. Reduction of uterine volumewas seen with aromatase inhibitors, GnRH analog, and LGN-IUD.
Conclusion
Levonorgestrel intrauterine system and dienogest have significantly improved the control of bleeding and pelvic pain, respectively, in women with adenomyosis. However, there is insufficient data from the retrieved studies to endorse eachmedication for this disease. Further randomized control tests (RCTs) are needed to address pharmacological treatment of adenomyosis.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Cristina Laguna Benetti-Pinto
-
Review Article03-24-2022
Commercial Surrogacy: An Overview
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(12):1141-1158
Views448This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleCommercial Surrogacy: An Overview
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(12):1141-1158
Views448See moreAbstract
Objective
Surrogacy is the process in which a woman carries and delivers a baby to other person or couple, known as intended parents. When carriers are paid for surrogacy, this is known as commercial surrogacy. The objective of the present work is to review the legal, ethical, social, and cultural aspects of commercial surrogacy, as well as the current panorama worldwide.
Methods
This is a review of the literature published in the 21st century on commercial surrogacy.
Results
A total of 248 articles were included as the core of the present review. The demand for surrogate treatments by women without uterus or with important uterine disorders, single men and same-sex male couples is constantly increasing worldwide. This reproductive treatment has important ethical dilemmas. In addition, legislation defers widely worldwide and is in constant change. Therefore, patients look more and more for treatments abroad, which can lead to important legal problems between countries with different laws. Commercial surrogacy is practiced in several countries, in most of which there is no specific legislation. Some countries have taken restrictive measures against this technique because of reports of exploitation of carriers.
Conclusion
Commercial surrogacy is a common practice, despite important ethical and legal dilemmas. As a consequence of diverse national legislations, patients frequently resort to international commercial surrogacy programs. As of today, there is no standard international legal context, and this practice remains largely unregulated.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article07-30-2021
The Female Athlete Triad/Relative Energy Deficiency in Sports (RED-S)
- Alexandra Ruivo Coelho
,
- Gonçalo Cardoso
,
- Marta Espanhol Brito
,
- Inês Neves Gomes
,
- Maria João Cascais
Views476This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleThe Female Athlete Triad/Relative Energy Deficiency in Sports (RED-S)
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):395-402
- Alexandra Ruivo Coelho
,
- Gonçalo Cardoso
,
- Marta Espanhol Brito
,
- Inês Neves Gomes
,
- Maria João Cascais
Views476See moreAbstract
In a healthy athlete, the caloric intake is sufficient for sports energy needs and body physiological functions, allowing a balance between energy availability, bone metabolism, andmenstrual cycle.Onthe other hand, an imbalance causedby low energy availability dueto a restrictive diet, eating disorders or long periods of energy expenditure leads to multisystemic deregulation favoring the essential functions of the body. This phenomenon, described as the female athlete triad, occurs in a considerable percentage of high-performance athletes, with harmful consequences for their future. The present review was carried out based on a critical analysis of themost recent publications available and aims to provide a global perception of the topic relative energy deficit in sport (RED-S). The objective is to promote theacquisition ofmore consolidated knowledgeon an undervaluedtheme, enabling the acquisition of preventive strategies, early diagnosis and/or appropriate treatment.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Alexandra Ruivo Coelho
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