Articles - Revista Brasileira de Ginecologia e Obstetrícia

  • Original Article09-02-2004

    Histological results and HPV detection in women with pap smear showing atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):457-462

    Abstract

    Original Article

    Histological results and HPV detection in women with pap smear showing atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):457-462

    DOI 10.1590/S0100-72032004000600006

    Views152

    OBJECTIVE: to assess the ability of Pap smear and hybrid capture II (HCII) to detect clinically significant cervical lesions (CIN2/3) in women referred to hospital due to atypical squamous cells of unknown significance (ASCUS) or low-grade squamous intraepithelial lesions (LSIL). METHODS: a cross-sectional study comprising 161 women referred to the Taubaté University Hospital due to ASCUS/LSIL, between August 2000 and September 2002. All women responded to a questionnaire regarding sociodemographic and reproductive characteristics and were subjected to gynecological examination with specimen collection for Pap test and HCII, along with colposcopy and eventual cervical biopsy. The relationship between HCII results and age, use of condom, oral hormonal contraception, and smoking were evaluated by the chi-square test. The sensitivity, specificity, positive and negative predictive values of both Pap test and HCII were calculated. All calculations were performed within 95% confidence intervals. RESULTS: sixty-seven percent of the women that tested positive for HPV were less than 30 years old. Pap smear and HCII showed the same 82% sensitivity in detecting CIN2/3 when the threshold for a positive Pap result was ASCUS, LSIL or HSIL. Pap smear specificity and positive predictive values were substantially increased when only HSIL results were considered as positive (from 29 to 95% and 12 to 50%, respectively). These figures were superior to those of HCII, but at the expense of an expressive loss of sensitivity (from 82% to 41%). CONCLUSIONS: our results substantiate the potential of HCII in detecting CIN2/3 among women referred due to ASCUS/LSIL.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article09-02-2004

    Effects of a contraceptive implant containing nomegestrol acetate on ovarian function, cervical mucus and sperm penetration

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):449-454

    Abstract

    Original Article

    Effects of a contraceptive implant containing nomegestrol acetate on ovarian function, cervical mucus and sperm penetration

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):449-454

    DOI 10.1590/S0100-72032004000600005

    Views98

    OBJECTIVE: to study the effect of a single contraceptive implant of nomegestrol acetate (Uniplant) on the ovarian function, cervical mucus production and sperm penetration, when inserted in women in the preovulatory phase. METHODS: twenty women with regular menstrual cycles were included in an open comparative study. All participants were investigated during one menstrual cycle before (control) and one menstrual cycle after implant insertion. Measurements of estradiol, LH, and progesterone, as well as transvaginal sonography, cervical mucus examination and sperm penetration test, were carried out. Statistical analysis was performed with the paired t-test and the non-parametric test of Wilcoxon. RESULTS: all control cycles were ovulatory and presented normal parameters. Preovulatory estradiol and LH peak decreased significantly from 603.2 ± 78.0 pmo/l and 22.5 ± 6.5 IU/l at pre-insertion to 380.7 ± 51.9 pmol/l and 4.9 ± 1.3 IU/l 48 hours after implant insertion (p < 0.05 and p < 0.01, respectively). Progesterone levels did not vary significantly (control cycle = 49.8 ± 3.3 nmol/l and treated cycle = 43.2 ± 5.2 nmol/l). Cervical mucus and sperm penetration tests were profoundly affected in 10.5% of the users 20 h after implant insertion, in 68.5% after 24 h and in 100% after 48 h. Follicular rupture occurred in the majority of the cycles 48 h after implant insertion. CONCLUSIONS: the use of a single implant of nomegestrol acetate affected estradiol and LH preovulatory peaks and disrupted the process of cervical mucus production and sperm penetration, but it was unable to prevent ovulation when inserted at the preovulatory phase, which reinforces the need to insert the implant during the first five days of the menstrual cycle.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article09-02-2004

    Comparison between Baden and Walker classification systems and ICS standardization of terminology of female pelvic organ prolapse

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):441-447

    Abstract

    Original Article

    Comparison between Baden and Walker classification systems and ICS standardization of terminology of female pelvic organ prolapse

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):441-447

    DOI 10.1590/S0100-72032004000600004

    Views89

    OBJECTIVE: to compare Baden and Walker’s (BW) classification system to the International Continence Society (ICS) standardization of terminology of female pelvic organ prolapse. METHODS: information about urogynecological investigation on 101 women, performed by the Urogynecology and Vaginal Surgery Sector of UNIFESP/EPM, was retrospectively analyzed. Only patients who had undergone the standard ICS exam which quantifies the pelvic prolapse were selected. According to ICS, the prolapse is analyzed through a standard reference system relating the hymen to the anatomic position of six vaginal points: two in the anterior vaginal wall, two in the vaginal apex and other two in the posterior vaginal wall. The maximum amount of pelvic organ prolapse was viewed and recorded during a Valsalva’s maneuver. The measurement of the most distal point of the prolapse was performed and it was compared to the BW classification system. The data were analyzed by kappa statistics, to assess the concordance between the two terminologies. RESULTS: There was total correspondence only for the posterior vaginal prolapse stage IV (one patient) and for the uterus prolapse stage 0 (29 patients) with severe rectocele and absence of prolapse, respectively, according to BW. In the three types of prolapses evaluated, the values of kappa statistics were below 0.4, indicating a weak concordance between the two terminologies. There is an extensive variation in the measurement of the most distal point of prolapse when the BW classification is perfomed. CONCLUSIONS: there is a weak concordance between the BW classification system and the ICS standardization of terminology of female pelvic organ prolapse.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article09-02-2004

    Ductal carcinoma in situ and invasive carcinoma in the same breast: evaluation of the nuclear grade and the expressions of proteins p53 and C-erbB-2 and estrogen receptors

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):435-439

    Abstract

    Original Article

    Ductal carcinoma in situ and invasive carcinoma in the same breast: evaluation of the nuclear grade and the expressions of proteins p53 and C-erbB-2 and estrogen receptors

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):435-439

    DOI 10.1590/S0100-72032004000600003

    Views66

    OBJECTIVES: The aim of the present study was to evaluate the nuclear grade, the expressions of p53 and c-erbB-2 proteins, and the estrogen receptors (ER) of 38 women with ductal carcinoma in situ (DCIS) and invasive carcinoma of the same breast. METHODS: the protein profile of 38 women was investigated in a descriptive and retrospective study, through the immune-histochemical technique. The cut-off limit for positive staining was chosen at 10% or more of positive cells for p53 and c-erbB-2 proteins and for ER. The analysis of the concordance between the expressions of proteins and the nuclear grade was done by the kappa coefficient, according to Landis and Koch’s criteria. MacNemar’s test was used to assess the differences between the two groups. RESULTS: there was a perfect concordance in the expression of p53 proteins (kappa coefficient = 1.00) and almost a perfect concordance for c-erbB-2 proteins, ER and nuclear grade (kappa coefficients = 0.84, 0.89 and 0.89) between in situ and invasive elements of the same tumor. CONCLUSION: there was no difference between the expressions of p53 and c-erbB-2 proteins, ER and nuclear grade in the DCIS and invasive carcinoma of the same breast.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article09-02-2004

    Serum leptin levels and bone mineral density in postmenopausal women

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):429-433

    Abstract

    Original Article

    Serum leptin levels and bone mineral density in postmenopausal women

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):429-433

    DOI 10.1590/S0100-72032004000600002

    Views146

    OBJECTIVE: to correlate serum leptin concentration with bone mineral density (BMD) in postmenopausal women. METHODS: twenty-two healthy postmenopausal women were included in the present study. BMD was measured by dual energy X-ray absorptiometry at the lumbar spine and femoral neck. Serum leptin concentrations were determined using an immunoradiometric assay. Statistical analysis was performed by ANOVA and Dunn and Pearson’s correlation tests. RESULTS: mean BMD values were 0.898 ± 0.140 g/cm² at the lumbar spine and 0.760 ± 0.152 g/cm² at the femoral neck. Mean serum leptin concentration was 17.2 ± 9.4 ng/ml and no significant differences were observed among women with normal BMD, osteopenia and osteoporosis (18.6 ± 7.8, 18.9 ± 9.9 and 15.6 ± 10.6, respectively; p > 0.05). No significant correlations were observed between serum leptin levels and BMD measurements at the lumbar spine and femoral neck, when the whole sample was considered and when patients were divided into groups with osteoporosis and/or osteopenia and a control group. We observed a positive significant correlation between serum leptin levels and body mass index (BMI) (r = 0.66; p = 0.0044). CONCLUSIONS: there was no direct correlation between leptin and BMD in postmenopausal women, although we observed positive significant correlation between leptin and BMI. This fact indicates a possible indirect effect of leptin on bone metabolism.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 09-02-2004
    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):427-427

    Abstract

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(6):427-427

    DOI 10.1590/S0100-72032004000600001

    Views27
    EDITORIAL Hospitais Universitários / pessoal Médico […]
    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Erratum08-04-2004
    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(5):420-420

    Abstract

    Erratum

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(5):420-420

    DOI 10.1590/S0100-72032004000500014

    Views36
    ERRATA Vol 26 (2): Páginas 89-96 […]
    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Thesis Abstract08-04-2004

    Amniotic infection in women held in public hospitals in Vitória-ES: prevalency, risc factors, diagnosis, histopathology and reproductive outcome

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(5):417-418

    Abstract

    Thesis Abstract

    Amniotic infection in women held in public hospitals in Vitória-ES: prevalency, risc factors, diagnosis, histopathology and reproductive outcome

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(5):417-418

    DOI 10.1590/S0100-72032004000500013

    Views46
    A postagem não tem conteúdo
    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Search

Search in:

Article type
Article type
abstract
book-review
brief-report
case-report
correction
editorial
letter
other
rapid-communication
research-article
review-article
Section
Section
Autors' Reply
Case Report
Clinical Consensus Recommendation
Editor's Note
Editorial
Equipments and Methods
Erratum
FEBRASGO POSITION STATEMENT
FIGO Statement
GUIDELINES
Integrative Review
Letter to the Editor
Nominata 2024
Original Article
Original Article/Contraception
Original Article/Infertility
Original Article/Obstetrics
Original Article/Oncology
Original Article/Sexual Violence/Pediatric and Adolescent Gynecology
Original Article/Teaching and Training
Previous Note
Reply to the Letter to the Editor
Resumos dos Trabalhos Premiados no 50º Congresso Brasileiro de Ginecologia e Obstetrícia
Review Article
Short Communication
Special Article
Systematic Review
Thesis Abstract
Year / Volume
Year / Volume
2025; v.47
2025; v.46
2024; v.46
2023; v.45
2022; v.44
2021; v.43
2020; v.42
2019; v.41
2018; v.40
2017; v.39
2016; v.38
2015; v.37
2014; v.36
2013; v.35
2012; v.34
2011; v.33
2010; v.32
2009; v.31
2008; v.30
2007; v.29
2006; v.28
2005; v.27
2004; v.26
2003; v.25
2002; v.24
2001; v.23
2000; v.22
1999; v.21
1998; v.20
ISSUE
ISSUE