Articles - Revista Brasileira de Ginecologia e Obstetrícia

Trabalhos Originais
Estimation of Fetal Weight: Comparison Between a Clinical Method and Ultrasonography
- Alexandre Faisal Cury,
- Sidney A. L. Garcia
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):551-555
04-05-1998

Views61

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Summary
Trabalhos Originais
Estimation of Fetal Weight: Comparison Between a Clinical Method and Ultrasonography
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):551-555
04-05-1998
DOI 10.1590/S0100-72031998001000002
Alexandre Faisal Cury,
Sidney A. L. Garcia
Views61
Purpose: to assess the validity of fetal weight estimation by a method based on uterine height — Johnson’s rule. Methods: one hundred and one pregnant women and their newborn children were studied. The fetal weight was estimated using an adaptation of Johnson’s rule, which consists of the clinical application of a mathematical model to calculate the fetal weight based on the uterine height and the height of fetal presentation. The estimated weight was obtained on the day of delivery and was compared to the weight observed after birth. This, in turn, was the control of the analysis of validity of the method used. On the same date, a detailed obstetrical ultrasonography (US) was conducted which included the fetal weight, calculated by the use of Sheppard’s tables. This weight, estimated by US, was compared to the birth weight. Results: the results have proven that the clinical estimate used in this study has a similar value to that of the US calculation of birth weight. The accuracy of the clinical method, with variations of 5%, 10% and 15% between estimated and observed weights, was 55.3%, 73% and 86.7%, respectively. Those of the US were 60.7%, 75.4% and 91.1%, respectively. When comparing both sets of figures, values were not different from a statistical standpoint. Conclusion: the clinical evaluation has shown to be accurate, similarly to the US, when calculating the birth weight.

Key-words Fetal weight Normal pregnancy Ultrasonography
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Resumos de Teses
Indice de líquido amniótico em gestantes diabéticas e a qualidade do controle glicêmico na gestação
- Fábio Sgarbosa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
04-05-1998

Views39

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Resumos de Teses
Indice de líquido amniótico em gestantes diabéticas e a qualidade do controle glicêmico na gestação
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
04-05-1998
DOI 10.1590/S0100-72031998000800011
Fábio Sgarbosa
Views39
Indice de Líquido Amniótico em Gestantes Diabéticas e a Qualidade do Controle Glicêmico na Gestação.[…]
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Resumos de Teses
Avaliação do grau nuclear da célula maligna da mama como parâmetro de atividade proliferativa tumoral: comparação com a expressão do antígeno nuclear de proliferação celular (PCNA/ciclina)
- Luiz Ayrton Santos Júnior
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
04-05-1998

Views51

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Resumos de Teses
Avaliação do grau nuclear da célula maligna da mama como parâmetro de atividade proliferativa tumoral: comparação com a expressão do antígeno nuclear de proliferação celular (PCNA/ciclina)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
04-05-1998
DOI 10.1590/S0100-72031998000800010
Luiz Ayrton Santos Júnior
Views51
Avaliação do Grau Nuclear da Célula Maligna da Mama como Parâmetro de Atividade Proliferativa Tumoral: Comparação com a Expressão do Antígeno Nuclear de Proliferação Celular (PCNA/ciclina).[…]
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Relato de Casos
Prenatal diagnosis of arthrogryposis multiplex congenita: a case report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):481-484
04-05-1998

Views60

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Summary
Relato de Casos
Prenatal diagnosis of arthrogryposis multiplex congenita: a case report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):481-484
04-05-1998
DOI 10.1590/S0100-72031998000800009
Carlos Augusto Alencar Júnior,
Francisco Edson de Lucena Feitosa,
Mac Gontei,
Sammya Bezerra Maia,
Dalgimar Beserra de Meneses
Views60
Arthrogryposis multiplex congenita is characterized by multiple joint contractures present at birth. Prenatal diagnosis is difficult. There are few reports in the literature. Fetal akinesia, abnormal limb position, intrauterine growth retardation, and polyhydramnios are the main findings of the ultrasonographic diagnosis. The authors describe a case of arthrogryposis multiplex congenita ultrasonographically diagnosed in the third gestational trimester. The main findings were absence of fetal movements, polyhydramnios, symmetrical and non-symmetrical fetal growth retardation with marked decrease of abdominal and thoracic circumference, low-set ears, micrognathia, continuous flexure contracture of limbs, internal rotation of the femur, and clubfoot on the right.

Key-words Fetal malformation prenatal diagnosis Ultrasonography
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Trabalhos Originais
Screening of breast cancer metastasis at preoperative work-up
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):475-479
04-05-1998

Views108

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Summary
Trabalhos Originais
Screening of breast cancer metastasis at preoperative work-up
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):475-479
04-05-1998
DOI 10.1590/S0100-72031998000800008
Maria Bethânia da Costa Chein,
Luciane Maria Oliveira Brito,
Simão Rotstein,
Luiz Henrique Gebrim,
Aldo Franklin F Reis,
Luciana Dessen Padilha
Views108
Purpose: to analyze the frequency of preoperative bilateral synchronic cancer and occult metastases in 454 operable breast cancer patients, at Instituto Nacional de Câncer (Brazil). Methods: the preoperative evaluation consisted of mammography, bone scan with X-ray if necessary, and chest X-ray. 260 (57.3 %) of 454 patients underwent liver echography. We calculated the cost X effectiveness ratio considering only the direct costs (monetary value) and the effectiveness was analyzed based on the number of metastases identifid by the screening tests. Results: we did not find any case of bilateral synchronic cancer, and the frequency of patients with metastasis was 2% (9/454). The diagnosis of bone metastasis was 1.5 % (7/454). The percentage of lung (2/454) and liver (1/260) metastasis was the same, 0.4 %. Most of the patients with metastases were in stage IIIb (44.5 %). The results of the screening tests showed the alteration of the initial clinical stage in 9 patients only (2%). The total cost of the screening tests for the diagnosis of systemic disease in 9 patients, was US$ 131,020.00. The cost of each diagnosed metastasise, for a total of 10 (two were found in one of the patients), was US$ 29,221.85 and the cost/effectiveness ratio was 22.3%. Conclusious: the results showed that screening for metastases in the preoperative clinical staging of breast cancer should be limited to patients symptomatic for systemic disease or in clinical stage III and that the cost/effectiveness ratio of the tests demonstrated a reduced benefit in the preoperative evaluation.

Key-words Breast cancer Health care costs Metastasis Ultrasonography
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Trabalhos Originais
Second-degree family history as a risk factor for breast cancer
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):469-473
04-05-1998

Views109

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Trabalhos Originais
Second-degree family history as a risk factor for breast cancer
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):469-473
04-05-1998
DOI 10.1590/S0100-72031998000800007
Rafael Marques de Souza,
Anderson Rech Lazzaron,
Rafael Defferrari,
Álvaro A. Borba,
Luciana Scherer,
Antônio L. Frasson
Views109
Purpose: to evaluate the association between second-degree family history of breast cancer and the risk to develop the disease. Methods: case-control study of incident cases. Sixty-six incident breast cancer cases and 198 controls were selected among women who were submitted to mammography in a private clinic between January 1994 and July 1997. Cases and controls were paired regarding age, age at menarche, at first live birth, at menopause, parity, oral contraceptives and use of hormonal replacement therapy. Results: there was no significant difference between cases and controls regarding all risk factors evaluated, besides second-degree family history. Patients with breast cancer were more likely to have second-degree relatives with breast cancer when compared to controls (OR=2.77; 95% CI, 1.03-7.38; p=0.039). Conclusions: malignant neoplasm of the breast is significantly associated with a second-degree family history of this disease.

Key-words Breast neoplasms Heredity Risk factors
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Trabalhos Originais
Fine needle aspiration biopsy: performance in the differential diagnosis of palpable breast masses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):463-467
04-05-1998

Views42

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Trabalhos Originais
Fine needle aspiration biopsy: performance in the differential diagnosis of palpable breast masses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):463-467
04-05-1998
DOI 10.1590/S0100-72031998000800006
Orlando José de Almeida,
Marcelo Alvarenga,
José Guilherme Cecatti,
Jessé de Paula Neves Jorge,
Júlia Kawamura Tambascia
Views42
Purpose: to evaluate, in a prospective way, the performance of the fine needle aspiration biopsy in the differential diagnosis of palpable breast masses. Method: the sensitivity, specificity, positive and negative predictive values for this test were evaluated in 102 women with age above 30 years and a palpable breast mass, who were attended at the University of Campinas. All punctures were performed by the same examiner. Results: the procedure had a sensitivity of 97%, specificity of 87%, positive predictive value of 94% and negative predictive value of 93%. The insufficient or unsatisfactory sample rate was 16% for the first aspiration, decreasing to 2% with a new procedure. Conclusions: this test showed to be highly sensitive and specific for the differential diagnosis of palpable breast masses, reassuring its great importance for the clinical approach of palpable masses.

Key-words Breast cancer Fine needle aspiration biopsy
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Trabalhos Originais
A randomized trial of misoprostol and placebo for cervical ripening and induction of labor
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):457-462
04-05-1998

Views86

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Summary
Trabalhos Originais
A randomized trial of misoprostol and placebo for cervical ripening and induction of labor
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):457-462
04-05-1998
DOI 10.1590/S0100-72031998000800005
Renata Murad Macedo,
Ivete de Ávila,
Manuel Maurício Gonçalves
Views86
Objective: to determine the efficacy and safety of misoprostol for cervical ripening and induction of labor in pregnant women at term when compared with placebo. Patients and Methods: fifty-one high-risk pregnant women at term, with unripe cervix, were allocated in a double-blind trial for treatment with intravaginal misoprostol (40 mg, 4/4 h) or intravaginal placebo. Results: thirty-two patients received misoprostol and 19 received placebo. The groups were homogeneous concerning maternal age, gestacional age, parity, and indication for induction (p > 0.05). In the misoprostol group the efficacy was 87.5% and in the placebo group 21.1% (p = 0.0000087). Regarding delivery, in the misoprostol group 75% had vaginal delivery and 25% abdominal delivery, and in the placebo group only 32% had vaginal delivery and 68% abdominal delivery (p = 0.0059).The Apgar score was similar. Conclusion: in this study misoprostol was effective and safe for cervical ripening and induction of labor.

Key-words Cervical ripening High risk pregnancy Induction of labor Pregnancy interruption Prostaglandin
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Original Article
Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo9
00-00-2024

Views392

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Summary
Original Article
Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo9
00-00-2024
DOI 10.61622/rbgo/2024AO09
Thaís Loureiro Felipe ,
Patrícia Paula da Fonseca Grili ,
Camila Vilarinho Vidigal ,
Ben-Hur Albergaria ,
Geise Ferreira da Cruz ,
José Luiz Marques-Rocha ,
Valdete Regina Guandalini
Views392
Abstract

Objective:

To analyze the amount of muscle and the presence of sarcopenia in postmenopausal women using different methods, verifying the agreement between them as to skeletal muscle mass (SMM).

Methods:

This cross-sectional observational study was conducted with postmenopausal women aged ≥ 50 years. SMM was obtained from a predictive equation, Bioelectrical Impedance (BIA), and Dual Energy X-Ray Absorptiometry (DXA). The skeletal muscle mass index (SMI) and the appendicular skeletal muscle mass index (ASMI) were calculated. The cut-off point of SMI was determined for the population itself. The agreement between the SMI obtained using the different methods was verified. Sarcopenia was diagnosed according to the criteria proposed by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2). The significance level adopted for all tests was 5.0%.

Results:

A total of 112 women were evaluated, with an average age of 66.1 ± 5.65 years. Among them, 51.8% were sufficiently active and 43.8% were overweight and obese. The SMI cut-offs were 6.46 kg/m² for the predictive equation and 7.66 kg/m² for BIA, with high sensitivity and specificity. There was an excellent agreement in the identification of SMM by the predictive equation (0.89 [0.824-0.917], p < 0.001) and BIA (0.92 [0.883-0.945], p < 0.001), in reference to DXA. The prevalence of sarcopenia was 0.9%, 1.8%, and 2.7% according to BIA, DXA, and the predictive equation, respectively.

Conclusion:

The predictive equation showed the expected agreement in estimating skeletal muscle mass in postmenopausal women, offering a viable and accurate alternative.

Key-words Anthropometry Bioelectrical impedance Body composition Muscle mass Obesity Overweight Postmenopause sarcopenia Skeletal Muscle
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Original Article
Sociodemographic and reproductive risk factors associated with metabolic syndrome in a population of Brazilian women from the city of Ribeirão Preto: a cross-sectional study
- Ênio Luis Damaso ,
- Heloisa Bettiol ,
- Viviane Cunha Cardoso ,
- Mariane Nunes de Nadai ,
- Elaine Christine Dantas Moisés ,
- Ricardo Carvalho Cavalli
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo8
00-00-2024

Views384

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Summary
Original Article
Sociodemographic and reproductive risk factors associated with metabolic syndrome in a population of Brazilian women from the city of Ribeirão Preto: a cross-sectional study
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo8
00-00-2024
DOI 10.61622/rbgo/2024AO08
Ênio Luis Damaso ,
Heloisa Bettiol ,
Viviane Cunha Cardoso ,
Mariane Nunes de Nadai ,
Elaine Christine Dantas Moisés ,
Carolina Sales Vieira ,
Ricardo Carvalho Cavalli
Views384
Abstract

Objective:

To identify sociodemographic and reproductive risk factors associated with MetS in women in their fourth decade of life.

Methods:

Cohort study conducted on women born from June 1978 to May 1979 in Ribeirão Preto, Brazil. Sociodemographic, clinical, and obstetric data were collected by interview and clinical evaluation. Univariable and multivariable binomial logistic regression models were constructed to identify the risk factors of metabolic syndrome and the adjusted relative risk (RR) was calculated.

Results:

The cohort included 916 women, and 286 (31.2%) of them have metabolic syndrome. MetS was associated with lack of paid work (RR 1.49; 95% CI 1.14-1.95), marital status of without a partner (RR 1.33; 95% CI 1.03-1.72), low educational level (less than 8 years of schooling [RR 1.72; 95% CI 1.23-2.41], 8 to 12 years of schooling [RR 1.37; 95% CI 1.06-1.76], when compared with more than 12 years of schooling), and teenage pregnancy (RR 2.00; 95% CI 1.45-2.77). There was no association between MetS, and the other covariates studied.

Conclusion:

Metabolic syndrome in a population of women in the fourth decade of life was associated with lack of employment, lack of a partner, low educational level, and teenage pregnancy.

Key-words cohort study metabolic syndrome Obesity Risk factors
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Original Article
Impact of doula’s continuous support on serotonin release in parturients: a pilot randomized clinical trial
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo27
04-09-2024

Views382

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Impact of doula’s continuous support on serotonin release in parturients: a pilot randomized clinical trial
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo27
04-09-2024
DOI 10.61622/rbgo/2024rbgo27
Eleonora de Deus Vieira de Moraes ,
Mayara Segundo Ribeiro ,
Cíntia Erbert ,
Caio Antonio de Campos Prado ,
Elaine Christine Dantas Moisés
Views382
Abstract

Objective:

To evaluate whether the continuous support provided by doulas influences the endogenous release of serotonin in parturients.

Methods:

This pilot study included 24 primigravidae at term. Of these, 12 women received continuous doula support (Experimental Group), whereas the other 12 received the usual assistance without doula support (Control Group). Blood samples were collected from all the women at the active and expulsion stages of labor and at the fourth period of labor (Greenberg period) for evaluation of their serotonin levels using high-performance liquid chromatography.

Results:

The average serotonin concentrations in the control and experimental groups were respectively 159.33 and 150.02 ng/mL at the active stage, 179.13 and 162.65 ng/mL at the expulsion stage, and 198.94 and 221.21 ng/mL at the Greenberg period. There were no statistically significant differences in serotonin concentrations between the two groups at the active and expulsion stages of labor. By contrast, within the experimental group, a significant increase in serotonin concentration was observed in the Greenberg period compared with the levels in the active and expulsion stages (p < 0.05).

Conclusion:

The novelty of this study relies on the ability to correlate the influence of the continuous support offered by doulas with the release of serotonin in parturients, with the results suggesting that the assistance received during labor can modulate the levels of hormone release in the Greenberg period.

Brazilian Registry of Clinical Trials:

RBR-4zjjm4h

Key-words Doulas Humanized delivery Labor Pregnant women Serotonin
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Editorial
RBGO – A journal to support gynecology and obstetrics research in Latin America
- Marcos Felipe Silva de Sá
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgoedt1
00-00-2024

Views377

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Summary
Editorial
RBGO – A journal to support gynecology and obstetrics research in Latin America
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgoedt1
00-00-2024
DOI 10.61622/rbgo/2024EDT01
Marcos Felipe Silva de Sá
Views377
In 2016, the Brazilian Federation of the Gynecology and Obstetrics Associations – FEBRASGO began a major restructuring process of the RBGO – Revista Brasileira de Ginecologia e Obstetrícia with significant changes in its editorial policy. Since that date, after the editorial board was reformulated, the articles began to be published in English with absolute regularity […]
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Original Article
Outcomes after elevation of serratus anterior fascia flap versus serratus muscle flap in direct-to-implant breast reconstruction following mastectomy: a prospective study
- Lilian de Sá Paz Ramos ,
- Jorge Villanova Biazús
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo13
00-00-2024

Views368

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Outcomes after elevation of serratus anterior fascia flap versus serratus muscle flap in direct-to-implant breast reconstruction following mastectomy: a prospective study
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo13
00-00-2024
DOI 10.61622/rbgo/2024AO13
Lilian de Sá Paz Ramos ,
Jorge Villanova Biazús
Views368
Abstract

Objective:

The purpose of this study was to compare postoperative pain between SF flap and serratus anterior muscle (SM) in direct-to-implant breast reconstruction.

Methods:

This is a prospective cohort study that included 53 women diagnosed with breast cancer who underwent mastectomy and one-stage implant-based breast reconstruction from January 2020 to March 2021. Twenty-nine patients (54.7%) had SF elevation, and 24 patients (45.3%) underwent SM elevation. We evaluated patient-reported early postoperative pain on the first day after surgery. Also, it was reported that all surgical complications in the first month and patient reported outcomes (PROs) were measured with the BRECON 23 questionnaire.

Results:

The serratus fascia group used implants with larger volumes, 407.6 ± 98.9 cc (p < 0.01). There was no significant difference between the fascial and muscular groups regarding the postoperative pain score reported by the patients (2 versus 3; p = 0.30). Also, there was no difference between the groups regarding early surgical complications and PROs after breast reconstruction.

Conclusion:

The use of SF seems to cause less morbidity, which makes the technique an alternative to be considered in breast reconstruction. Although there was no statistical difference in postoperative pain scores between the fascia and serratus muscle groups.

Key-words Breast implants Breast neoplasms breast reconstruction Fascia Mastectomy Pain Postoperative period
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Original Article/Infertility
The Role of Thyroid Hormones, Vitamins, and Microelements in Female Infertility
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(11):683-688
12-05-2023

Views364

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Summary
Original Article/Infertility
The Role of Thyroid Hormones, Vitamins, and Microelements in Female Infertility
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(11):683-688
12-05-2023
DOI 10.1055/s-0043-1772478
Aghayeva Sveta ,
Murat Sonmezer ,
Yavuz Emre Şükür ,
Aytaj Jafarzade
Views364
Abstract

Objective

It is well known that female infertility is multifactorial. Therefore, we aimed to compare the effects of thyroid dysfunction, vitamin deficiency, and microelement deficiency in fertile and infertile patients.

Materials and Methods

Between May 1st, 2017, and April 1st, 2019, we conducted a retrospective case-control study with of 380 infertile and 346 pregnant patients (who normally fertile and able to conceive spontaneously). The fertile patients were selected among those who got pregnant spontaneously without treatment, had a term birth, and did not have systemic or obstetric diseases. The levels of thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), anti-thyroid peroxidase (anti-TPO), vitamin D, vitamin B12, folic acid, ferritin, and zinc of both groups were compared.

Results

There was no difference between patients in the infertile and pregnant groups in terms of low normal and high serum T3 and T4 levels (p = 0.938; p > 0.05) respectively, nor in terms of normal and high anti-TPO levels (p = 0.182; p > 0.05) respectively. There was no significant difference regarding patients with low, insufficient, and sufficient vitamin D levels in the infertile and pregnant groups (p = 0.160; p >0.05) respectively. The levels of folic acid, ferritin, and zinc of the infertile group were significantly lower than those of the pregnant group.

Conclusion

The serum levels of folic acid, ferritin, and zinc in infertile patients presenting to our outpatient clinic were lower than those o the fertile patients.

Key-words ferritin Folic acid Infertility thyroid hormones Vitamin B12 vitamin D zinc
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Review Article
Timing of semen cryopreservation: before or after processing?
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo36
04-09-2024

Views355

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Review Article
Timing of semen cryopreservation: before or after processing?
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo36
04-09-2024
DOI 10.61622/rbgo/2024rbgo36
Ana Paula de Souza Kussler ,
Ivan Cunha Bustamante Filho ,
Elisa Negri ,
Edison Capp ,
Helena von Eye Corleta
Views355
Abstract

Objective:

Seminal cryopreservation causes significant damage to the sperm; therefore, different methods of cryopreservation have been studied. The aim of the study was to compare the effects of density gradient processing and washing/centrifugation with seminal plasma removal for cryopreservation in semen parameters.

Methods:

Seminal samples of 26 normozoospermic patients were divided into 3 parts: with seminal plasma; after washing/centrifugation; and after selection through density gradient. The samples were cryopreserved for at least two weeks. Motility, sperm count, morphology and viability were evaluated before cryopreservation and after thawing.

Results:

Density gradient processing selected motile and viable sperm with normal morphology in fresh samples (p<0.05). Cryopreservation negatively affected all sperm parameters regardless of the processing performed, and even if the sperm recovery was lower in the density gradient after the thawing, progressive motility, total motility, viability and morphology remained higher (p<0.05).

Conclusion:

Cryopreservation significantly compromises sperm parameters (motility, morphology, viability). In normozoospermic patients, the density gradients select better quality spermatozoa compared to other processing methods; this benefit was kept after thawing.

Key-words Centrifugation Cryopreservation Density gradient Semen Seminal plasma Sperm count Sperm wash Spermatozoa
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Original Article
Comparison of medical image interpretation time between conventional and automated methods of breast ultrasound
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo15
00-00-2024

Views352

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Summary
Original Article
Comparison of medical image interpretation time between conventional and automated methods of breast ultrasound
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo15
00-00-2024
DOI 10.61622/rbgo/2024AO15
Katyane Larissa Alves ,
Ruffo Freitas Junior ,
Régis Resende Paulinelli ,
Marcus Nascimento Borges
Views352
Abstract

Objective:

To compare the medical image interpretation’s time between the conventional and automated methods of breast ultrasound in patients with breast lesions. Secondarily, to evaluate the agreement between the two methods and interobservers.

Methods:

This is a cross-sectional study with prospective data collection. The agreement’s degrees were established in relation to the breast lesions’s ultrasound descriptors. To determine the accuracy of each method, a biopsy of suspicious lesions was performed, considering the histopathological result as the diagnostic gold standard.

Results:

We evaluated 27 women. Conventional ultrasound used an average medical time of 10.77 minutes (± 2.55) greater than the average of 7.38 minutes (± 2.06) for automated ultrasound (p<0.001). The degrees of agreement between the methods ranged from 0.75 to 0.95 for researcher 1 and from 0.71 to 0.98 for researcher 2. Among the researchers, the degrees of agreement were between 0.63 and 1 for automated ultrasound and between 0.68 and 1 for conventional ultrasound. The area of the ROC curve for the conventional method was 0.67 (p=0.003) for researcher 1 and 0.72 (p<0.001) for researcher 2. The area of the ROC curve for the automated method was 0. 69 (p=0.001) for researcher 1 and 0.78 (p<0.001) for researcher 2.

Conclusion:

We observed less time devoted by the physician to automated ultrasound compared to conventional ultrasound, maintaining accuracy. There was substantial or strong to perfect interobserver agreement and substantial or strong to almost perfect agreement between the methods.

Key-words Breast neoplasms breast ultrasound Diagnostic imaging three-dimensional imaging
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Original Article
School-based HPV Vaccination: The Challenges in a Brazilian Initiative
- Julio Cesar Teixeira ,
- Mariana Silva Castro Vianna ,
- Diama Bhadra Vale ,
- Daniella Moretti Arbore ,
- Thais Helena Wilmers Perini ,
- Luiz Carlos Zeferino
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(12):926-931
01-24-2021

Views219

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Summary
Original Article
School-based HPV Vaccination: The Challenges in a Brazilian Initiative
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(12):926-931
01-24-2021
DOI 10.1055/s-0041-1740279
Julio Cesar Teixeira ,
Mariana Silva Castro Vianna ,
Diama Bhadra Vale ,
Daniella Moretti Arbore ,
Thais Helena Wilmers Perini ,
Tulio Jose Tomass Couto ,
Jose Pedroso Neto ,
Luiz Carlos Zeferino
Views219
Abstract

Objective

The present study assesses the implementation and the impact after 2 years of a school-based human papillomavirus (HPV) vaccination program in a Brazilian city.

Methods

A prospective study assessing the implementation of the program, offering quadrivalent HPV vaccine in two annual doses to girls and boys aged from 9 to 10 years old. The program was started in the city of Indaiatuba, state of São Paulo, Brazil, in 2018, and had authorization from the National Immunization Program. The number of HPV vaccine first doses applied and the coverage in 2018 was calculated and compared to the year 2017. There were described events that have influenced the results.

Results

The program invited 4,878 children through schools (87.1% of the target population), and 7.5% refused vaccination. Several concurrent events required or competed for health professionals of the vaccination teams. The coverage of the first dose (between 9 and 10 years old) was 16.1% in 2017 and increased to 50.5% in 2018 (p < 0.0001). The first dose in all ages increased 78% in 2018 compared with 2017 (6,636/3,733). Competing demands over the program continued in 2019, and the first dose coverage dropped (26.9%). For 2020, a municipal law instituted school-based vaccination and the creation of dedicated teams for vaccination, and these strategies are waiting to be tested.

Conclusion

School-based annual HPV vaccination in children between 9 and 10 years old was feasible and increased vaccination coverage, regardless of gender, although the program was vulnerable to competing events.

Key-words Adolescents HPV vaccine Human papillomavirus schools Vaccination
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Case Report
Lipschütz Ulcer: An Unusual Diagnosis that Should Not be Neglected
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):414-416
07-30-2021

Views184

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Summary
Case Report
Lipschütz Ulcer: An Unusual Diagnosis that Should Not be Neglected
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):414-416
07-30-2021
DOI 10.1055/s-0041-1729147
Daniela Alexandra Gonçalves Pereira ,
Eliana Patrícia Pereira Teixeira ,
Ana Cláudia Martins Lopes ,
Ricardo José Pina Sarmento ,
Ana Paula Calado Lopes
Views184
Abstract

The diagnosis of genital ulcers remains a challenge in clinical practice. Lipschütz ulcer is a non-sexually transmitted rare and, probably, underdiagnosed condition, characterized by the sudden onset of vulvar edema along with painful necrotic ulcerations. Despite its unknown incidence, this seems to be an uncommon entity, with sparse cases reported in the literature. We report the case of an 11-year-old girl who presented at the emergency department with vulvar ulcers. She denied any sexual intercourse. The investigation excluded sexually transmitted infections, so, knowledge of different etiologies of non-venereal ulcers became essential. The differential diagnoses are extensive and include inflammatory processes, drug reactions, trauma, and malignant tumors. Lipschütz ulcer is a diagnosis of exclusion. With the presentation of this case report, the authors aim to describe the etiology, clinical course, and outcomes of this rare disease, to allow differential diagnosis of genital ulceration.

Key-words Adolescent non-venereal lesions vulvar ulcer
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Original Article
The Pathway of Female Couples in a Fertility Clinic
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(7):660-666
06-03-2022

Views143

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
The Pathway of Female Couples in a Fertility Clinic
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(7):660-666
06-03-2022
DOI 10.1055/s-0042-1744444
Pedro Brandão ,
Nathan Ceschin ,
Victor Hugo Gómez
Views143
Abstract

Objective

The present study aims to describe the main characteristics of female couples resorting to a fertility clinic, to understand whether these patients have clear previous plans concerning procreation and how they end up completing their family planning, and to briefly describe the main outcomes of the recepción de ovocitos de pareja (ROPA, in the Spanish acronym: in English, reception of partner’s oocytes) method.

Methods

This is a descriptive retrospective study of the pathway and outcomes of female couples in a fertility clinic during a 2-year period.

Results

A total of 129 couples were treated. Only one third of the couples had no condition potentially affecting fertility or advanced age. Most couples were decided to undergo artificial insemination or in vitro fertilization and the majority kept their plans, as opposed to 38% of the couples who decided to the ROPA method (lesbian shared in vitro fertilization) who changed plans. Live birth rates per treatment (including frozen embryo transfers) for artificial insemination, 58% for in vitro fertilization, 80% for treatments with donated oocytes or embryos, and 79% for ROPA. Four in five couples achieved live births.

Conclusion

The present study highlights the importance of a thorough medical workup in same-sex couples resorting to assisted reproduction. Despite the higher-than-expected rates of fertility disorders, the outcomes were good. Most couples end up in a single parented method. Furthermore, the results of the ROPA method are reassuring.

Key-words assisted donor conception Fertilization in vitro homosexuality Reproductive techniques ROPA
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Original Article
Risk Factors for Intrapartum Cesarean Section Delivery in Low-risk Multiparous Women Following at Least a Prior Vaginal Birth (Robson Classification 3 and 4)
- Gul Nihal Buyuk ,
- Hatice Kansu-Celik ,
- Zeynep Asli Oskovi Kaplan ,
- Burcu Kisa ,
- Sule Ozel ,
- Yaprak Engin-Ustun
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):436-441
07-27-2021

Views131

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Risk Factors for Intrapartum Cesarean Section Delivery in Low-risk Multiparous Women Following at Least a Prior Vaginal Birth (Robson Classification 3 and 4)
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):436-441
07-27-2021
DOI 10.1055/s-0041-1731378
Gul Nihal Buyuk ,
Hatice Kansu-Celik ,
Zeynep Asli Oskovi Kaplan ,
Burcu Kisa ,
Sule Ozel ,
Yaprak Engin-Ustun
Views131
Abstract

Objective

The aim of the present study was to evaluate the risk factors for cesarean section (C-section) in low-risk multiparous women with a history of vaginal birth.

Methods

The present retrospective study included low-risk multiparous women with a history of vaginal birth who gave birth at between 37 and 42 gestational weeks. The subjects were divided into 2 groups according to the mode of delivery, as C-section Group and vaginal delivery Group. Risk factors for C-section such as demographic characteristics, ultrasonographic measurements, smoking, weight gain during pregnancy (WGDP), interval time between prior birth, history of macrosomic birth, and cervical dilatation at the admission to the hospital were obtained fromthe charts of the patients. Obstetric and neonatal outcomes were compared between groups.

Results

The most common C-section indications were fetal distress and macrosomia (33.9% [n=77 and 20.7% [n=47] respectively). A bivariate correlation analysis demonstrated that mothers aged>30 years old (odds ratio [OR]: 2.09; 95% confidence interval [CI]: 1.30-3.34; p=0.002), parity >1 (OR: 1.81; 95%CI: 1.18-2.71; p=0.006), fetal abdominal circumference (FAC) measurement>360mm (OR: 34.20; 95%CI: 8.04 -145.56; p<0.001)) and<345mm (OR: 3.06; 95%CI: 1.88-5; p<0.001), presence of large for gestational age (LGA) fetus (OR: 5.09; 95%CI: 1.35-19.21; p=0.016), premature rupture of membranes (PROM) (OR: 1.52; 95%CI: 1-2.33; p=0.041), and cervical dilatation<5cm at admission (OR: 2.12; 95%CI: 1.34-3.34; p=0.001) were associated with the group requiring a C-section.

Conclusion

This is the first study evaluating the risk factors for C-section in low-risk multiparous women with a history of vaginal birth according to the Robson classification 3 and 4. Fetal distress and suspected fetal macrosomia constituted most of the Csection indications.

Key-words cervical dilatation Cesarean section fetal abdominal circumference Risk factors Vaginal delivery
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Review
Dietary Patterns during Pregnancy and Gestational Weight Gain: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(5):540-547
04-28-2022

Views208

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Summary
Review
Dietary Patterns during Pregnancy and Gestational Weight Gain: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(5):540-547
04-28-2022
DOI 10.1055/s-0042-1744290
Larissa Bueno Ferreira ,
Cecília Viana Lobo ,
Aline Elizabeth da Silva Miranda ,
Brenda da Cunha Carvalho ,
Luana Caroline dos Santos
Views208
Abstract

The present systematic review (PROSPERO: CRD42020148630) hypothesizes the association of excessive weight gain during pregnancywith dietary patterns composed of ultraprocessed foods. Thus, the objective was to investigate the association between dietary patterns after analysis and weight gain during pregnancy. The search for articles was performed in nine databases. Two reviewers selected the articles in the databases and extracted from them the data used in the review. Two scales were used to evaluate the quality of the selected studies: New Castle-Ottawa Quality Assessment for cohort-based studies and Appraisal tool for Cross-Sectional Studies (AXIS) for cross-sectional-based studies. In total, 11 studies were identified with sample size variation (n=173-5,733). Women presenting more adherence to healthy and traditional patterns (fruits, vegetables, salads, nuts, and dairy) recorded less excessive gestational weight gain (GWG). Higher intake ofmixed patterns and western patterns rich in ultraprocessed foods were associated with a higher prevalence of excessive GWG (24.48- 55.20%). Gestational dietary patterns a posteriori-derived that have presented ultraprocessed components rich in fat and sugars presented association with high GWG; healthy and traditional dietary patterns were related to better mother-child health conditions, such as adequate GWG.

Key-words diets gestational dietary patterns Pregnancy Pregnant women Weight gain
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Original Article
COVID-19 in Pregnancy: Implication on Platelets and Blood Indices
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(8):595-599
11-15-2021

Views142

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
COVID-19 in Pregnancy: Implication on Platelets and Blood Indices
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(8):595-599
11-15-2021
DOI 10.1055/s-0041-1733912
Wassan Nori ,
Ban Hadi Hameed ,
Asmaa Rajih Thamir ,
Amenah Fadhil
Views142
Abstract

Objective

To describe the hematological changes, the platelet indices in particular, in pregnant women with coronavirus disease 2019 (COVID-19) compared to healthy pregnant women.

Methods

A retrospective case-control study conducted at the Al Yarmouk Teaching Hospital, in Baghdad, Iraq, involving 100 pregnant women, 50 with positive viral DNA for COVID-19 (case group), and 50 with negative results (control group); both groups were subjected to a thorough hematological evaluation.

Results

Among the main hematological variables analyzed, the platelet indices, namely the mean platelet volume (MPV) and the platelet distribution width (PDW), showed statistically significant differences (MPV: 10.87±66.92 fL for the case group versus 9.84±1.2 fL for the control group; PDW: 14.82±3.18 fL for the case group versus 13.3±2.16 fL for the controls). The criterionvalue of the receiver operating characteristic (ROC) curve forPDWat a cutoffpoint of>11.8 fL showed a weak diagnostic marker, while the MPV at a cutoff value of>10.17 fL showed a good diagnostic marker.

Conclusion

The MPV and PDW are significantly affected by the this viral infection, even in asymptomatic confirmed cases, and we recommend that both parameters be included in the diagnostic panel of this infection.

Key-words COVID-19 Mean platelet volume platelet distribution width platelet indices Pregnancy
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Original Article
Association between Prenatal Care Adequacy Indexes and Low Birth Weight Outcome
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(4):256-263
06-18-2021

Views149

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Association between Prenatal Care Adequacy Indexes and Low Birth Weight Outcome
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(4):256-263
06-18-2021
DOI 10.1055/s-0041-1728779
Conceição Christina Rigo Vale ,
Nubia Karla de Oliveira Almeida ,
Renan Moritz Varnier Rodrigues de Almeida
Views149
Abstract

Objective

To investigate the association between prenatal care (PNC) adequacy indexes and the low birth weigth (LBW) outcome.

Methods

A total of 368,093 live term singleton births in the state of Rio de Janeiro (Brazil) from 2015 to 2016 were investigated using data from the Brazilian Live Birth Information System (Sistema de Informações sobre Nascidos Vivos, SINASC, in Portuguese). Seven PNC adequacy indexes were evaluated: four developed by Brazilian authors (Ciari Jr. et al., Coutinho et al., Takeda, and an index developed and used by the Brazilian Ministry of Health – MS) and three by authors from other countries (Kessner et al., the Adequacy of Prenatal Care Utilization index – APNCU, and the Graduated Prenatal Care Utilization Index – GINDEX). Adjusted odds ratios were estimated for the PNC adequacy indexes by means of multivariate logistic regression models using maternal, gestational and newborn characteristics as covariates.

Results

When the PNC is classified as “inadequate”, the adjusted odds ratios to the LBWoutcome increase between 42% and 132%, depending on which adequacy index is evaluated. Younger (15 to 17 years old) and older (35 to 45 years old) mothers, those not married, of black or brown ethnicity, with low schooling (who did not finish Elementary School), primiparous, with preterm births, as well as female newborns had increasing odds for LBW. The models presented areas under the receiver operating characteristic (ROC) curve between 80.4% and 81.0%, and sensitivity and specificity that varied, respectively, between 57.7% and 58.6% and 94.3% and 94.5%.

Conclusion

Considering all PNC adequacy indexes evaluated, the APNCU had the best discriminatory power and the best ability to predict the LBW outcome.

Key-words Low birth weight maternal and newborn health perinatal epidemiology Prenatal care
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Original Article
The Impact of the COVID-19 Pandemic on Depression and Sexual Function: Are Pregnant Women Affected More Adversely?
- Ramazan Denizli ,
- Önder Sakin ,
- Kazibe Koyuncu ,
- Nayif Çiçekli ,
- Nihat Farisoğulları ,
- Mikail Özdemir
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(10):765-774
12-17-2021

Views154

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
The Impact of the COVID-19 Pandemic on Depression and Sexual Function: Are Pregnant Women Affected More Adversely?
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(10):765-774
12-17-2021
DOI 10.1055/s-0041-1736174
Ramazan Denizli ,
Önder Sakin ,
Kazibe Koyuncu ,
Nayif Çiçekli ,
Nihat Farisoğulları ,
Mikail Özdemir
Views154
Abstract

Objective

To investigate depression and sexual function among pregnant and nonpregnant women throughout the COVID-19 pandemic.

Methods

A total of 188 women, 96 pregnant and 92 non-pregnant were included. The Beck Depression Inventory (BDI) and the Arizona Sexual Experience Scale (ASEX) were applied to the participants after obtaining sociodemographic data.

Results

The depression scores of pregnant and non-pregnant women were similar (p = 0.846). We found that the depression scores were significantly higher among the group of participants who have lower economic status (p = 0.046). Moreover, the depression score was significantly higher among women who lost their income during the pandemic (p = 0.027). The score on the ASEX was significantly higher, and sexual dysfunction was more prevalent among women who have lower levels of schooling and income (p < 0.05). Likewise, the ASEX scores were significantly higher (p = 0.019) among the group who experienced greater income loss throughout the pandemic. Upon comparing the pregnant and non-pregnant groups, we detected that sexual dysfunction had a significantly higher rate among pregnant women (p < 0.001).

Conclusion

In times of global crisis, such as the current pandemic, low-income families have an increased risk of experiencing depression and sexual dysfunction. When we compared pregnant women with non-pregnant women, depression scores were similar, but pregnant women were at a 6.2 times higher risk of developing sexual dysfunction.

Key-words COVID-19 Depression pandemic pregnant sexual function
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Estimation of Fetal Weight: Comparison Between a Clinical Method and Ultrasonography

Indice de líquido amniótico em gestantes diabéticas e a qualidade do controle glicêmico na gestação

Avaliação do grau nuclear da célula maligna da mama como parâmetro de atividade proliferativa tumoral: comparação com a expressão do antígeno nuclear de proliferação celular (PCNA/ciclina)

Prenatal diagnosis of arthrogryposis multiplex congenita: a case report

Screening of breast cancer metastasis at preoperative work-up

Second-degree family history as a risk factor for breast cancer

Fine needle aspiration biopsy: performance in the differential diagnosis of palpable breast masses

A randomized trial of misoprostol and placebo for cervical ripening and induction of labor

Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women

Abstract

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Sociodemographic and reproductive risk factors associated with metabolic syndrome in a population of Brazilian women from the city of Ribeirão Preto: a cross-sectional study

Abstract

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Impact of doula’s continuous support on serotonin release in parturients: a pilot randomized clinical trial

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Brazilian Registry of Clinical Trials:

RBGO – A journal to support gynecology and obstetrics research in Latin America

Outcomes after elevation of serratus anterior fascia flap versus serratus muscle flap in direct-to-implant breast reconstruction following mastectomy: a prospective study

Abstract

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The Role of Thyroid Hormones, Vitamins, and Microelements in Female Infertility

Abstract

Objective

Materials and Methods

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Conclusion

Timing of semen cryopreservation: before or after processing?

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Methods:

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Comparison of medical image interpretation time between conventional and automated methods of breast ultrasound

Abstract

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Results:

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School-based HPV Vaccination: The Challenges in a Brazilian Initiative

Abstract

Objective

Methods

Results

Conclusion

Lipschütz Ulcer: An Unusual Diagnosis that Should Not be Neglected

Abstract

The Pathway of Female Couples in a Fertility Clinic

Abstract

Objective

Methods

Results

Conclusion

Risk Factors for Intrapartum Cesarean Section Delivery in Low-risk Multiparous Women Following at Least a Prior Vaginal Birth (Robson Classification 3 and 4)

Abstract

Objective

Methods

Results

Conclusion

Dietary Patterns during Pregnancy and Gestational Weight Gain: A Systematic Review

Abstract

COVID-19 in Pregnancy: Implication on Platelets and Blood Indices

Abstract

Objective

Methods

Results

Conclusion