Articles - Revista Brasileira de Ginecologia e Obstetrícia

  • Original Article10-06-2000

    The Relationship between White’s Classification and the Histopathological Changes in the Placentas of Diabetic Pregnant Women

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):401-411

    Abstract

    Original Article

    The Relationship between White’s Classification and the Histopathological Changes in the Placentas of Diabetic Pregnant Women

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):401-411

    DOI 10.1590/S0100-72032000000700002

    Views79

    Purpose: to analyze the relationship between White’s classification and the histopathological, changes occurring in the placentas of diabetic pregnant women, performing a qualitative comparison of histopathological changes in the placentas of nondiabetic pregnant women with those in diabetic ones (classes A and A/B), clinical, short duration (classes B and C), and clinical with vasculopathy (classes D to FRH), studying the influence of the quality of glycemic control and of gestational age on placental changes in the three groups of diabetic pregnant women. Patients and methods: specimens of placentas were collected from all diabetic pregnant women seen between 1991 and 1996 in the Maternity Section of the Hospital das Clínicas, Faculdade de Medicina de Botucatu, stained using the hematoxylin-eosin technique, and submitted to a histopathological examination. The quality of glycemic control was analyzed by the glycemia average of gestation and classified as adequate or inadequate, with a limit of 120 mg/dl. Gestational age was individualized as term and preterm. Results: forty-two newborns (43.3%) were born at term and the remaining were preterm (56.7%). The prematurity rate was higher for women with clinical diabetes (classes B and C; D to FRH). Some histopathological alterations were observed only in placentas from diabetic pregnant women: cystoid degeneration, chorial edema, intima edema, dysmaturity, Hofbauer cell hyperplasia, villitis, ghost cells, two vessels in the umbilical cord, and endarteritis. Conclusions: histopathological changes in the placentas of pregnant women with gestational diabetes (classes A and A/B), clinical, short duration (classes B and C), and clinical with vasculopathy (classes D to FRH) were similar to those in the nondiabetic ones, and, therefore, were independent of White’s clinical classification. The histopathological changes in the placentas of pregnant women with gestational diabetes (classes A and A and B), clinical, short duration (classes B and C), and clinical with vasculopathy (classes D to FRH) were not related to gestational age at birth and to the quality of glycemic control of the mother. The comparison between histopathological changes and the increased number of preterm newborns in clinical diabetes, class D to FRH, suggest early placental ageing in clinical diabetes patients.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 10-03-2000

    Avaliação da Quantidade do Colágeno da Pele de Ratas Castradas após o Uso de Estrogênio, Progestagênio e Tamoxifeno

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):462-462

    Abstract

    Avaliação da Quantidade do Colágeno da Pele de Ratas Castradas após o Uso de Estrogênio, Progestagênio e Tamoxifeno

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):462-462

    DOI 10.1590/S0100-72032000000700016

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    Avaliação da Quantidade do Colágeno da Pele de Ratas Castradas após o Uso de Estrogênio, Progestagênio e Tamoxifeno[…]
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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 10-03-2000

    Estudo Comparativo de Sistemas de Graduação em Preparados Citológicos e Histológicos para Carcinoma Infiltrante de Ductos Mamários. Avaliação da Concordância Cito-Histológica

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):461-462

    Abstract

    Estudo Comparativo de Sistemas de Graduação em Preparados Citológicos e Histológicos para Carcinoma Infiltrante de Ductos Mamários. Avaliação da Concordância Cito-Histológica

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):461-462

    DOI 10.1590/S0100-72032000000700015

    Views80
    Estudo Comparativo de Sistemas de Graduação em Preparados Citológicos e Histológicos para Carcinoma Infiltrante de Ductos Mamários. Avaliação da Concordância Cito-Histológica[…]
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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 10-03-2000

    Misoprostol como Indutor do Trabalho de Parto em Gestantes com Feto Vivo a Termo

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):460-460

    Abstract

    Misoprostol como Indutor do Trabalho de Parto em Gestantes com Feto Vivo a Termo

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):460-460

    DOI 10.1590/S0100-72032000000700012

    Views58
    Misoprostol como Indutor do Trabalho de Parto em Gestantes com Feto Vivo a Termo[…]
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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 10-03-2000

    Estudo Comparativo entre a Punção Aspirativa por Agulha Fina e a Biópsia de Fragmento Guiadas por Ultra-som no Diagnóstico de Lesões Mamárias Suspeitas de Malignidade

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):460-460

    Abstract

    Estudo Comparativo entre a Punção Aspirativa por Agulha Fina e a Biópsia de Fragmento Guiadas por Ultra-som no Diagnóstico de Lesões Mamárias Suspeitas de Malignidade

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):460-460

    DOI 10.1590/S0100-72032000000700013

    Views62
    Estudo Comparativo entre a Punção Aspirativa por Agulha Fina e a Biópsia de Fragmento Guiadas por Ultra-som no Diagnóstico de Lesões Mamárias Suspeitas de Malignidade[…]
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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 10-03-2000

    Estudo de Fatores Relacionados com a Violência Sexual contra Crianças, Adolescentes e Mulheres Adultas

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):459-459

    Abstract

    Estudo de Fatores Relacionados com a Violência Sexual contra Crianças, Adolescentes e Mulheres Adultas

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):459-459

    DOI 10.1590/S0100-72032000000700011

    Views70
    Estudo de Fatores Relacionados com a Violência Sexual contra Crianças, Adolescentes e Mulheres Adultas[…]
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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 10-03-2000

    Avaliação do Tratamento Não-Medicamentoso (Orientação Verbal) das Mastalgias Cíclicas

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):459-459

    Abstract

    Avaliação do Tratamento Não-Medicamentoso (Orientação Verbal) das Mastalgias Cíclicas

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):459-459

    DOI 10.1590/S0100-72032000000700010

    Views71
    Avaliação do Tratamento Não-Medicamentoso (Orientação Verbal) das Mastalgias Cíclicas[…]
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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Case Report10-03-2000

    Angiosarcoma of the Breast: Case Report

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):455-458

    Abstract

    Case Report

    Angiosarcoma of the Breast: Case Report

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):455-458

    DOI 10.1590/S0100-72032000000700009

    Views126

    Primary angiosarcoma of the breast is a rare tumor, which appears between 14 and 82 years, with an average of 35 years of age. Its predominant clinical aspect is a painful mass with diffuse increase in the breast and violet or blackened color. Equally to other cases of sarcoma, the medium size of the lesion is approximately 5 cm at the diagnosis. Histologically, it is characterized by the proliferation of endothelial cells that form vascular channels linked to each other infiltrating glandular structures and fatty tissue. Its histological diagnosis is difficult and not always the right diagnosis is immediately established, mainly in the cases of a low malignancy degree, due to limited biopsy material. Because of the difficult diagnosis and aggressivity, it is a neoplasia with ominous prognosis, due to frequent metastasis. In our service, a 18-year-old patient presented with a painful lump which grew quickly. It was biopsied and a hemangioma was diagnosed, a wide excision being indicated. Three months later, she suffered a tumoral relapse, that was biopsied again and mastectomy was indicated, because it was an angiosarcoma with low degree of malignancy. After other relapses, chemotherapy was indicated and later, radiotherapy. During radiotherapy she developed new metastases, and died of pulmonary metastasis.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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