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Original Article07-30-2021
Placental Sampling for Understanding Viral Infections – A Simplified Protocol for the COVID-19 Pandemic
- Guilherme de Moraes Nobrega
, - José Paulo Siqueira Guida ,
- Rodolfo Rosa Japecanga ,
- Arthur Antolini-Tavares ,
- Indira Mysorekar , [ ... ],
- Maria Laura Costa
Abstract
Original ArticlePlacental Sampling for Understanding Viral Infections – A Simplified Protocol for the COVID-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):377-383
- Guilherme de Moraes Nobrega ,
- José Paulo Siqueira Guida ,
- Rodolfo Rosa Japecanga ,
- Arthur Antolini-Tavares ,
- Indira Mysorekar ,
- Maria Laura Costa
Views155See moreAbstract
Objective
The coronavirus disease 2019 (COVID-19) is a pandemic viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The impact of the disease among the obstetric population remains unclear, and the study of the placenta can provide valuable information. Adequate sampling of the placental tissue can help characterize the pathways of viral infections.
Methods
A protocol of placental sampling is proposed, aiming at guaranteeing representativity of the placenta and describing the adequate conservation of samples and their integrity for future analysis. The protocol is presented in its complete and simplified versions, allowing its implementation in different complexity settings.
Results
Sampling with the minimum possible interval from childbirth is the key for adequate sampling and storage. This protocol has already been implemented during the Zika virus outbreak.
Conclusion
A protocol for adequate sampling and storage of placental tissue is fundamental for adequate evaluation of viral infections on the placenta. During the COVID-19 pandemic, implementation of this protocol may help to elucidate critical aspects of the SARS-CoV-2 infection.
Views155
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePlacental Sampling for Understanding Viral Infections – A Simplified Protocol for the COVID-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):377-383
- Guilherme de Moraes Nobrega ,
- José Paulo Siqueira Guida ,
- Rodolfo Rosa Japecanga ,
- Arthur Antolini-Tavares ,
- Indira Mysorekar ,
- Maria Laura Costa
Views155See moreAbstract
Objective
The coronavirus disease 2019 (COVID-19) is a pandemic viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The impact of the disease among the obstetric population remains unclear, and the study of the placenta can provide valuable information. Adequate sampling of the placental tissue can help characterize the pathways of viral infections.
Methods
A protocol of placental sampling is proposed, aiming at guaranteeing representativity of the placenta and describing the adequate conservation of samples and their integrity for future analysis. The protocol is presented in its complete and simplified versions, allowing its implementation in different complexity settings.
Results
Sampling with the minimum possible interval from childbirth is the key for adequate sampling and storage. This protocol has already been implemented during the Zika virus outbreak.
Conclusion
A protocol for adequate sampling and storage of placental tissue is fundamental for adequate evaluation of viral infections on the placenta. During the COVID-19 pandemic, implementation of this protocol may help to elucidate critical aspects of the SARS-CoV-2 infection.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Guilherme de Moraes Nobrega
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Original Article07-30-2021
Comparison between Enzyme Immunoassays Performed on Samples of Dried Blood and Serum for Toxoplasmosis Prenatal Screening: Population-based Study
- Bárbara Araújo Marques ,
- Ericka Vianna Machado Carellos ,
- Vânia Maria Novato Silva ,
- Fernando Henrique Pereira ,
- Maria Regina Lage Guerra , [ ... ],
- Gláucia Manzan Queiroz de Andrade
Abstract
Original ArticleComparison between Enzyme Immunoassays Performed on Samples of Dried Blood and Serum for Toxoplasmosis Prenatal Screening: Population-based Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):351-356
- Bárbara Araújo Marques ,
- Ericka Vianna Machado Carellos ,
- Vânia Maria Novato Silva ,
- Fernando Henrique Pereira ,
- Maria Regina Lage Guerra ,
- Jacqueline Araújo Domingos Iturra ,
- José Nélio Januário ,
- Gláucia Manzan Queiroz de Andrade
Views184Abstract
Objective
Most prenatal screening programs for toxoplasmosis use immunoassays in serum samples of pregnant women. Few studies assess the accuracy of screening tests in dried blood spots, which are of easy collection, storage, and transportation. The goals of the present study are to determine the performance and evaluate the agreement between an immunoassay of dried blood spots and a reference test in the serum of pregnant women from a population-based prenatal screening program for toxoplasmosis in Brazil.
Methods
A cross-sectional study was performed to compare the immunoassays Imunoscreen Toxoplasmose IgM and Imunoscreen Toxoplasmose IgG (Mbiolog Diagnósticos, Ltda., Contagem, Minas Gerais, Brazil)in dried blood spots with the enzymelinked fluorescent assay (ELFA, BioMérieux S.A., Lyon, France) reference standard in the serum of pregnant women from Minas Gerais Congenital Toxoplasmosis Control Program.
Results
The dried blood spot test was able to discriminate positive and negative results of pregnant women when comparedwith the reference test, with an accuracy of 98.2% for immunoglobulin G (IgG), and of 95.8% for immunoglobulin M (IgM).
Conclusion
Dried blood samples are easy to collect, store, and transport, and they have a good performance,making this a promisingmethod for prenatal toxoplasmosis screening programs in countries with continental dimensions, limited resources, and a high prevalence of toxoplasmosis, as is the case of Brazil.
Key-words Congenital toxoplasmosisdried blood spot testingPrenatal careprenatal diagnosisToxoplasmosisSee moreViews184This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleComparison between Enzyme Immunoassays Performed on Samples of Dried Blood and Serum for Toxoplasmosis Prenatal Screening: Population-based Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):351-356
- Bárbara Araújo Marques ,
- Ericka Vianna Machado Carellos ,
- Vânia Maria Novato Silva ,
- Fernando Henrique Pereira ,
- Maria Regina Lage Guerra ,
- Jacqueline Araújo Domingos Iturra ,
- José Nélio Januário ,
- Gláucia Manzan Queiroz de Andrade
Views184Abstract
Objective
Most prenatal screening programs for toxoplasmosis use immunoassays in serum samples of pregnant women. Few studies assess the accuracy of screening tests in dried blood spots, which are of easy collection, storage, and transportation. The goals of the present study are to determine the performance and evaluate the agreement between an immunoassay of dried blood spots and a reference test in the serum of pregnant women from a population-based prenatal screening program for toxoplasmosis in Brazil.
Methods
A cross-sectional study was performed to compare the immunoassays Imunoscreen Toxoplasmose IgM and Imunoscreen Toxoplasmose IgG (Mbiolog Diagnósticos, Ltda., Contagem, Minas Gerais, Brazil)in dried blood spots with the enzymelinked fluorescent assay (ELFA, BioMérieux S.A., Lyon, France) reference standard in the serum of pregnant women from Minas Gerais Congenital Toxoplasmosis Control Program.
Results
The dried blood spot test was able to discriminate positive and negative results of pregnant women when comparedwith the reference test, with an accuracy of 98.2% for immunoglobulin G (IgG), and of 95.8% for immunoglobulin M (IgM).
Conclusion
Dried blood samples are easy to collect, store, and transport, and they have a good performance,making this a promisingmethod for prenatal toxoplasmosis screening programs in countries with continental dimensions, limited resources, and a high prevalence of toxoplasmosis, as is the case of Brazil.
Key-words Congenital toxoplasmosisdried blood spot testingPrenatal careprenatal diagnosisToxoplasmosisSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Bárbara Araújo Marques
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Original Article07-30-2021
Gynecological/Obstetric Background and Rheumatoid Arthritis: A Cross-sectional Study in Brazilian Patients
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):357-361
Abstract
Original ArticleGynecological/Obstetric Background and Rheumatoid Arthritis: A Cross-sectional Study in Brazilian Patients
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):357-361
Views139See moreAbstract
Objective
To study a sample of rheumatoid arthritis (RA) patients for their gynecological/obstetric history and compare them to controls to determine their influences on number of pregnancies, menarche, menopause and reproductive years following RA onset.
Methods
This is a cross-sectional study of 122 RA patients and 126 controls. Patients and controls were questioned about age of menarche, age of menopause, number of pregnancies and abortions. Reproductive years were calculated as the difference between age at menopause and age at menarche. For comparison, we used the Mann-Whitney, unpaired t, chi-squared, and Spearman tests. The adopted significance was 5%.
Results
In the RA patients with disease beginning in the postmenopausal years, the period of reproductive years (age at menopause - age of menarche) showed a positive correlation with age at disease onset (rho=0.46; 95% confidence interval [CI]=0.20- 0.55 with p=0.0008). The number of pregnancies was higher in patients with postmenopausal disease onset when compared with those with premenopausal disease onset (median of 3 with interquartile range [IQR]=2-4 versus median of 2 with IQR=1-3; p=0.009), and RA patients had more pregnancies than controls (p=0.0002).
Conclusion
The present study shows that, in our population, the duration of reproductive years and the number of pregnancies are linked to the onset of RA.
Views139This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleGynecological/Obstetric Background and Rheumatoid Arthritis: A Cross-sectional Study in Brazilian Patients
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):357-361
Views139See moreAbstract
Objective
To study a sample of rheumatoid arthritis (RA) patients for their gynecological/obstetric history and compare them to controls to determine their influences on number of pregnancies, menarche, menopause and reproductive years following RA onset.
Methods
This is a cross-sectional study of 122 RA patients and 126 controls. Patients and controls were questioned about age of menarche, age of menopause, number of pregnancies and abortions. Reproductive years were calculated as the difference between age at menopause and age at menarche. For comparison, we used the Mann-Whitney, unpaired t, chi-squared, and Spearman tests. The adopted significance was 5%.
Results
In the RA patients with disease beginning in the postmenopausal years, the period of reproductive years (age at menopause - age of menarche) showed a positive correlation with age at disease onset (rho=0.46; 95% confidence interval [CI]=0.20- 0.55 with p=0.0008). The number of pregnancies was higher in patients with postmenopausal disease onset when compared with those with premenopausal disease onset (median of 3 with interquartile range [IQR]=2-4 versus median of 2 with IQR=1-3; p=0.009), and RA patients had more pregnancies than controls (p=0.0002).
Conclusion
The present study shows that, in our population, the duration of reproductive years and the number of pregnancies are linked to the onset of RA.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article07-30-2021
Barriers to Puberty Talk between Mothers and Daughters: A Qualitative Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):362-367
Abstract
Original ArticleBarriers to Puberty Talk between Mothers and Daughters: A Qualitative Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):362-367
Views144See moreAbstract
Objective
The aim of the present study is to explain the barriers to puberty talk between mothers and daughters.
Methods
In the present study, the conventional content analysis method was used. The present study was conducted from September 2018 to August 2019 in Iran. The study population consisted of mothers and adolescent girls. The data was collected using purposeful sampling method. The sample consisted of 4 mothers and 6 girls that were interviewed using semistructured interviews. Data collection continued until data saturation was achieved. Data analysis was conducted as described by Graneheimet al. using NVivo 11 software.
Results
In the present study, after exploring the views of the participants about barriers to puberty talk between mothers and daughters, one dominant theme emerged. Puberty talk is seen as an “inappropriate talk with a girl.” There were several subthemes, including “lack of mother’s awareness regarding the school role, the busy schedule of the mother, and the adoption of alternatives to mother’s talk with girls”.
Conclusions
Different sociocultural factors affect puberty talk between mothers and adolescent girls. It is important thatmothers and policymakers take these barriers intoaccount.
Views144This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleBarriers to Puberty Talk between Mothers and Daughters: A Qualitative Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):362-367
Views144See moreAbstract
Objective
The aim of the present study is to explain the barriers to puberty talk between mothers and daughters.
Methods
In the present study, the conventional content analysis method was used. The present study was conducted from September 2018 to August 2019 in Iran. The study population consisted of mothers and adolescent girls. The data was collected using purposeful sampling method. The sample consisted of 4 mothers and 6 girls that were interviewed using semistructured interviews. Data collection continued until data saturation was achieved. Data analysis was conducted as described by Graneheimet al. using NVivo 11 software.
Results
In the present study, after exploring the views of the participants about barriers to puberty talk between mothers and daughters, one dominant theme emerged. Puberty talk is seen as an “inappropriate talk with a girl.” There were several subthemes, including “lack of mother’s awareness regarding the school role, the busy schedule of the mother, and the adoption of alternatives to mother’s talk with girls”.
Conclusions
Different sociocultural factors affect puberty talk between mothers and adolescent girls. It is important thatmothers and policymakers take these barriers intoaccount.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article07-30-2021
Immunological Characteristics between αβ TDC and γδ TDC Cells in the Spleen of Breast Cancer-Induced Mice
- Polyana Barbosa Silva ,
- Márcia Antoniazi Michelin ,
- Millena Prata Jammal ,
- Eddie Fernando Cândido Murta
Abstract
Original ArticleImmunological Characteristics between αβ TDC and γδ TDC Cells in the Spleen of Breast Cancer-Induced Mice
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):368-373
- Polyana Barbosa Silva ,
- Márcia Antoniazi Michelin ,
- Millena Prata Jammal ,
- Eddie Fernando Cândido Murta
Views151See moreAbstract
Objective
To evaluate the antitumoral role of γδ TDC cells and αβ TDC cells in an experimental model of breast cancer.
Methods
Thirty female Balb/c mice were divided into 2 groups: control group (n=15) and induced-4T1 group (n=15), in which the mice received 2 x 105 4T1 mammary tumor cell line. Following the 28-day experimental period, immune cells were collected from the spleen and analyzed by flow cytometry for comparison of αβ TDC (TCRαβ+ CD11c+MHCII+) and γδ TDC (TCRγδ+CD11c+MHCII+) cells regarding surface markers (CD4+ and C8+) and cytokines (IFN-γ, TNF-α, IL-12 and IL-17).
Results
A total of 26.53% of γδ TDC- control group (p<0.0001) - the proportion of αβ TDC was lower in splenic cells than γδ TDC; however, these 2 cell types were reduced in tumor conditions (p<0.0001), and the proportion of IFN-γ, TNF-α, IL-12 and IL-17 cytokines produced by γδ TDC was higher than those produced by αβ TDC, but it decreased under conditions of tumor-related immune system response (p<0.0001).
Conclusion
Healthy mice engrafted with malignant cells 4T1 breast tumor presented TDC with γδ TCR repertoire. These cells express cytotoxic molecules of lymphocytes T, producing anti-tumor proinflammatory cytokines.
Views151This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleImmunological Characteristics between αβ TDC and γδ TDC Cells in the Spleen of Breast Cancer-Induced Mice
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):368-373
- Polyana Barbosa Silva ,
- Márcia Antoniazi Michelin ,
- Millena Prata Jammal ,
- Eddie Fernando Cândido Murta
Views151See moreAbstract
Objective
To evaluate the antitumoral role of γδ TDC cells and αβ TDC cells in an experimental model of breast cancer.
Methods
Thirty female Balb/c mice were divided into 2 groups: control group (n=15) and induced-4T1 group (n=15), in which the mice received 2 x 105 4T1 mammary tumor cell line. Following the 28-day experimental period, immune cells were collected from the spleen and analyzed by flow cytometry for comparison of αβ TDC (TCRαβ+ CD11c+MHCII+) and γδ TDC (TCRγδ+CD11c+MHCII+) cells regarding surface markers (CD4+ and C8+) and cytokines (IFN-γ, TNF-α, IL-12 and IL-17).
Results
A total of 26.53% of γδ TDC- control group (p<0.0001) - the proportion of αβ TDC was lower in splenic cells than γδ TDC; however, these 2 cell types were reduced in tumor conditions (p<0.0001), and the proportion of IFN-γ, TNF-α, IL-12 and IL-17 cytokines produced by γδ TDC was higher than those produced by αβ TDC, but it decreased under conditions of tumor-related immune system response (p<0.0001).
Conclusion
Healthy mice engrafted with malignant cells 4T1 breast tumor presented TDC with γδ TCR repertoire. These cells express cytotoxic molecules of lymphocytes T, producing anti-tumor proinflammatory cytokines.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Polyana Barbosa Silva
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Original Article07-27-2021
Risk Factors for Intrapartum Cesarean Section Delivery in Low-risk Multiparous Women Following at Least a Prior Vaginal Birth (Robson Classification 3 and 4)
- Gul Nihal Buyuk ,
- Hatice Kansu-Celik ,
- Zeynep Asli Oskovi Kaplan ,
- Burcu Kisa ,
- Sule Ozel , [ ... ],
- Yaprak Engin-Ustun
Abstract
Original ArticleRisk Factors for Intrapartum Cesarean Section Delivery in Low-risk Multiparous Women Following at Least a Prior Vaginal Birth (Robson Classification 3 and 4)
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):436-441
- Gul Nihal Buyuk ,
- Hatice Kansu-Celik ,
- Zeynep Asli Oskovi Kaplan ,
- Burcu Kisa ,
- Sule Ozel ,
- Yaprak Engin-Ustun
Views169Abstract
Objective
The aim of the present study was to evaluate the risk factors for cesarean section (C-section) in low-risk multiparous women with a history of vaginal birth.
Methods
The present retrospective study included low-risk multiparous women with a history of vaginal birth who gave birth at between 37 and 42 gestational weeks. The subjects were divided into 2 groups according to the mode of delivery, as C-section Group and vaginal delivery Group. Risk factors for C-section such as demographic characteristics, ultrasonographic measurements, smoking, weight gain during pregnancy (WGDP), interval time between prior birth, history of macrosomic birth, and cervical dilatation at the admission to the hospital were obtained fromthe charts of the patients. Obstetric and neonatal outcomes were compared between groups.
Results
The most common C-section indications were fetal distress and macrosomia (33.9% [n=77 and 20.7% [n=47] respectively). A bivariate correlation analysis demonstrated that mothers aged>30 years old (odds ratio [OR]: 2.09; 95% confidence interval [CI]: 1.30-3.34; p=0.002), parity >1 (OR: 1.81; 95%CI: 1.18-2.71; p=0.006), fetal abdominal circumference (FAC) measurement>360mm (OR: 34.20; 95%CI: 8.04 -145.56; p<0.001)) and<345mm (OR: 3.06; 95%CI: 1.88-5; p<0.001), presence of large for gestational age (LGA) fetus (OR: 5.09; 95%CI: 1.35-19.21; p=0.016), premature rupture of membranes (PROM) (OR: 1.52; 95%CI: 1-2.33; p=0.041), and cervical dilatation<5cm at admission (OR: 2.12; 95%CI: 1.34-3.34; p=0.001) were associated with the group requiring a C-section.
Conclusion
This is the first study evaluating the risk factors for C-section in low-risk multiparous women with a history of vaginal birth according to the Robson classification 3 and 4. Fetal distress and suspected fetal macrosomia constituted most of the Csection indications.
Key-words cervical dilatationCesarean sectionfetal abdominal circumferenceRisk factorsVaginal deliverySee moreViews169This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleRisk Factors for Intrapartum Cesarean Section Delivery in Low-risk Multiparous Women Following at Least a Prior Vaginal Birth (Robson Classification 3 and 4)
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):436-441
- Gul Nihal Buyuk ,
- Hatice Kansu-Celik ,
- Zeynep Asli Oskovi Kaplan ,
- Burcu Kisa ,
- Sule Ozel ,
- Yaprak Engin-Ustun
Views169Abstract
Objective
The aim of the present study was to evaluate the risk factors for cesarean section (C-section) in low-risk multiparous women with a history of vaginal birth.
Methods
The present retrospective study included low-risk multiparous women with a history of vaginal birth who gave birth at between 37 and 42 gestational weeks. The subjects were divided into 2 groups according to the mode of delivery, as C-section Group and vaginal delivery Group. Risk factors for C-section such as demographic characteristics, ultrasonographic measurements, smoking, weight gain during pregnancy (WGDP), interval time between prior birth, history of macrosomic birth, and cervical dilatation at the admission to the hospital were obtained fromthe charts of the patients. Obstetric and neonatal outcomes were compared between groups.
Results
The most common C-section indications were fetal distress and macrosomia (33.9% [n=77 and 20.7% [n=47] respectively). A bivariate correlation analysis demonstrated that mothers aged>30 years old (odds ratio [OR]: 2.09; 95% confidence interval [CI]: 1.30-3.34; p=0.002), parity >1 (OR: 1.81; 95%CI: 1.18-2.71; p=0.006), fetal abdominal circumference (FAC) measurement>360mm (OR: 34.20; 95%CI: 8.04 -145.56; p<0.001)) and<345mm (OR: 3.06; 95%CI: 1.88-5; p<0.001), presence of large for gestational age (LGA) fetus (OR: 5.09; 95%CI: 1.35-19.21; p=0.016), premature rupture of membranes (PROM) (OR: 1.52; 95%CI: 1-2.33; p=0.041), and cervical dilatation<5cm at admission (OR: 2.12; 95%CI: 1.34-3.34; p=0.001) were associated with the group requiring a C-section.
Conclusion
This is the first study evaluating the risk factors for C-section in low-risk multiparous women with a history of vaginal birth according to the Robson classification 3 and 4. Fetal distress and suspected fetal macrosomia constituted most of the Csection indications.
Key-words cervical dilatationCesarean sectionfetal abdominal circumferenceRisk factorsVaginal deliverySee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Gul Nihal Buyuk
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Original Article07-27-2021
Prevalence and Determinants of Adequate Compliance with Antenatal Care in Peru
- Cesar Tello-Torres ,
- Akram Hernández-Vásquez ,
- Karla F. Dongo ,
- Rodrigo Vargas-Fernández ,
- Guido Bendezu-Quispe
Abstract
Original ArticlePrevalence and Determinants of Adequate Compliance with Antenatal Care in Peru
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):442-451
- Cesar Tello-Torres ,
- Akram Hernández-Vásquez ,
- Karla F. Dongo ,
- Rodrigo Vargas-Fernández ,
- Guido Bendezu-Quispe
Views242Abstract
Objective
To determine the adequacy of compliance with antenatal care (ANC) by pregnant women in Peru and to identify the associated factors.
Methods
An analytical cross-sectional study of data from the 2019 Peruvian Demographic and Family Health Survey (Encuesta Demográfica y de Salud Familiar, ENDES, in Spanish) was conducted. The dependent variable was adequate compliance with ANC (provided by skilled health care professionals; first ANC visit during the first trimester of pregnancy; six or more ANC visits during pregnancy; ANC visits with appropriate content) by women aged 15 to 49 years in their last delivery within the five years prior to the survey. Crude and adjusted prevalence ratios and their 95% confidence intervals were calculated using a log-binomial regression model.
Results
A total of 18,386 women were analyzed, 35.0% of whom adequately complied with ANC. The lowest proportion of compliance was found with the content of ANC (42.6%). Sociodemographic factors and those related to pregnancy, such as being in the age groups of 20 to 34 years and 35 to 49 years, havingsecondaryor higher education, belonging to a wealth quintile of the population other than the poorest, being from the Amazon region, not being of native ethnicity, having a second or third pregnancy, and having a desired pregnancy, increased the probability of presenting adequate compliance with ANC.
Conclusion
Only 3 out of 10women in Peru showed adequate compliancewith ANC. Compliance with the content of ANC must be improved, and strategies must be developed to increase the proportion of adequate compliance with ANC.
Key-words Cross-sectional studiesHealth surveysmaternal healthMaternal health servicesPeruPrenatal careQuality of health careSee moreViews242This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePrevalence and Determinants of Adequate Compliance with Antenatal Care in Peru
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):442-451
- Cesar Tello-Torres ,
- Akram Hernández-Vásquez ,
- Karla F. Dongo ,
- Rodrigo Vargas-Fernández ,
- Guido Bendezu-Quispe
Views242Abstract
Objective
To determine the adequacy of compliance with antenatal care (ANC) by pregnant women in Peru and to identify the associated factors.
Methods
An analytical cross-sectional study of data from the 2019 Peruvian Demographic and Family Health Survey (Encuesta Demográfica y de Salud Familiar, ENDES, in Spanish) was conducted. The dependent variable was adequate compliance with ANC (provided by skilled health care professionals; first ANC visit during the first trimester of pregnancy; six or more ANC visits during pregnancy; ANC visits with appropriate content) by women aged 15 to 49 years in their last delivery within the five years prior to the survey. Crude and adjusted prevalence ratios and their 95% confidence intervals were calculated using a log-binomial regression model.
Results
A total of 18,386 women were analyzed, 35.0% of whom adequately complied with ANC. The lowest proportion of compliance was found with the content of ANC (42.6%). Sociodemographic factors and those related to pregnancy, such as being in the age groups of 20 to 34 years and 35 to 49 years, havingsecondaryor higher education, belonging to a wealth quintile of the population other than the poorest, being from the Amazon region, not being of native ethnicity, having a second or third pregnancy, and having a desired pregnancy, increased the probability of presenting adequate compliance with ANC.
Conclusion
Only 3 out of 10women in Peru showed adequate compliancewith ANC. Compliance with the content of ANC must be improved, and strategies must be developed to increase the proportion of adequate compliance with ANC.
Key-words Cross-sectional studiesHealth surveysmaternal healthMaternal health servicesPeruPrenatal careQuality of health careSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Cesar Tello-Torres
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Original Article07-27-2021
Prenatal Diagnosis of Aberrant Right Subclavian Artery: Association with Genetic Abnormalities
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):452-456
Abstract
Original ArticlePrenatal Diagnosis of Aberrant Right Subclavian Artery: Association with Genetic Abnormalities
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):452-456
Views182See moreAbstract
Objective
The objective of the present study was to determine the frequency of malformations and chromosomal abnormalities in a population of fetuses with an aberrant right subclavian artery (ARSA).
Methods
This is a 6-year retrospective study of fetuses with a prenatal diagnosis of ARSA conducted during the period between September 2013 and June 2019 at a fetal medicine unit. Data were collected from ultrasound, fetal echocardiograms, genetic studies, and neonatal records.
Results
An ARSA was diagnosed in 22 fetuses. An ARSA was an isolated finding in 18 out of 22 cases (82%). Associated abnormal sonographic findings were found in 4 cases. All cases underwent invasive testing. In 1 of the cases, a chromosomal abnormality was detected (mos 45,X [13]/46,X,e(X) (p22.1q22.1)). No cases of congenital heart disease were found in any of these fetuses. There were two cases in which the postnatal evaluation revealed amalformation: one case of hypospadias and 1 case of cleft palate.
Conclusion
The presence of an isolated ARSA is benign and is not associated with chromosomal abnormalities. The finding of ARSA, however, warrants a detailed fetal ultrasound in order to exclude major fetal abnormalities and other soft markers.
Views182This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePrenatal Diagnosis of Aberrant Right Subclavian Artery: Association with Genetic Abnormalities
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):452-456
Views182See moreAbstract
Objective
The objective of the present study was to determine the frequency of malformations and chromosomal abnormalities in a population of fetuses with an aberrant right subclavian artery (ARSA).
Methods
This is a 6-year retrospective study of fetuses with a prenatal diagnosis of ARSA conducted during the period between September 2013 and June 2019 at a fetal medicine unit. Data were collected from ultrasound, fetal echocardiograms, genetic studies, and neonatal records.
Results
An ARSA was diagnosed in 22 fetuses. An ARSA was an isolated finding in 18 out of 22 cases (82%). Associated abnormal sonographic findings were found in 4 cases. All cases underwent invasive testing. In 1 of the cases, a chromosomal abnormality was detected (mos 45,X [13]/46,X,e(X) (p22.1q22.1)). No cases of congenital heart disease were found in any of these fetuses. There were two cases in which the postnatal evaluation revealed amalformation: one case of hypospadias and 1 case of cleft palate.
Conclusion
The presence of an isolated ARSA is benign and is not associated with chromosomal abnormalities. The finding of ARSA, however, warrants a detailed fetal ultrasound in order to exclude major fetal abnormalities and other soft markers.
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Original Article Archives - Revista Brasileira de Ginecologia e Obstetrícia
