Original Article Archives - Revista Brasileira de Ginecologia e Obstetrícia

  • Original Article

    Anemia levels in the preconception period and the first trimester of pregnancy: a national, multicentric and cross-sectional study

    Revista Brasileira de Ginecologia e Obstetrícia. 02-13-2025;47:-e-rbgo1001

    Summary

    Original Article

    Anemia levels in the preconception period and the first trimester of pregnancy: a national, multicentric and cross-sectional study

    Revista Brasileira de Ginecologia e Obstetrícia. 02-13-2025;47:-e-rbgo1001

    DOI 10.61622/rbgo/2025rbgo10001

    Views90

    Abstract

    Objective

    The study aimed to determine the level of anemia in pregnant women in the first trimester and in the preconception period by conducting nationwide research.

    Methods

    The study was designed as retrospective, cross-sectional, and multicenter research. A total of 17 centers from 13 provinces were included in the study. The study was conducted with the participation of two groups of patients who applied to the obstetrics polyclinic between 1 January 2023 and 1 July 2023, who were in the first trimester of pregnancy and who were in the preconception period planning pregnancy.

    Results

    In total 4,265 women were included in the study. Of these women, 3,884 (91%) were in the first trimester of their pregnancy and 381 (9%) were in the preconception period. Anemia was detected in 24.1% (n=1030) of the patients. Of these patients, 20.6% (n=877) were pregnant women in the first trimester and 3.6% (n=153) were in the preconception period. A statistically significant and positive relationship was found between anemia and meat consumption frequency, educational status, and socioeconomic status of the patients (p=0.000, p=0.000, p=0.000). In addition, a statistically significant and negative correlation was determined between anemia and the number of pregnancies and the parity number (p=0.001, p=0.000) in both groups.

    Conclusion

    Anemia is a public health problem. Anemia has been determined to be an important problem both in the preconception period and early periods of pregnancy. It is necessary to revise the programs and interventions to reduce the prevalence of anemia and redesign them in line with current conditions.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    Anemia levels in the preconception period and the first trimester of pregnancy: a national, multicentric and cross-sectional study
  • Original Article

    A comparison of the efficacy of the effect of online versus face-to-face group counseling based on positive-approach on sexual intimacy of women after benign abdominal hysterectomy: a clinical trial

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo102

    Summary

    Original Article

    A comparison of the efficacy of the effect of online versus face-to-face group counseling based on positive-approach on sexual intimacy of women after benign abdominal hysterectomy: a clinical trial

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo102

    DOI 10.61622/rbgo/2024rbgo102

    Views164

    Abstract

    Objective

    The study investigates the influence of positive-approach counseling through both online and face-to-face group therapy on the sexual intimacy of women after benign complete abdominal hysterectomy, addressing challenges such as the loss of femininity and other psychosexual complications that disrupt the couple’s relationship post-surgery.

    Methods

    This is a parallel clinical trial, conducted in 2023 in Yazd, Iran; with sixty-six participants post- benign complete abdominal hysterectomy were randomly assigned to online and face-to-face counseling groups. Each group had eight 90-minute sessions, and data were collected using demographic and intimacy scale (IS) questionnaires at baseline, eighth week, and twelfth week follow-up. Statistical analysis used SPSS version 23 (P < 0.05).

    Results

    In the Online Group, the mean sexual intimacy score significantly increased from 72.42 ± 9.05 to 87.06 ± 7.98 at eight weeks and 90.30 ± 8.23 at twelve weeks (P < 0.001). In the Face-to-Face Group, the mean score increased from 70.21 ± 6.75 to 81.24 ± 5.55 at eight weeks and 85.03 ± 5.40 at twelve weeks (P < 0.001). Online counseling proved more effective than face-to-face counseling in enhancing sexual intimacy (P = 0.043).

    Conclusion

    Online and face-to-face counseling based on the positive approach improved sexual intimacy in women with a history of benign hysterectomy. Moreover, it seems that online counseling was more effective, so it is recommended that this method be employed in follow-up sessions after hysterectomy. Iranian Registry of Clinical Trials - IRCT20230209057373N1

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    A comparison of the efficacy of the effect of online versus face-to-face group counseling based on positive-approach on sexual intimacy of women after benign abdominal hysterectomy: a clinical trial
  • Original Article

    Comparison of serum ischemia modified albumin levels between preeclamptic and healthy pregnant women

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo97

    Summary

    Original Article

    Comparison of serum ischemia modified albumin levels between preeclamptic and healthy pregnant women

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo97

    DOI 10.61622/rbgo/2024rbgo97

    Views186

    Abstract

    Objective

    Our aims to compare level of serum ischemia modified albümin(IMA) between healthy and preeclamptic pregnancies and to evaluate the relationship of IMA with preeclampsia, preeclampsia severity and perinatal outcomes.

    Methods

    Our study is a prospective case-control study. A total of 134 pregnant women (66 preeclamptic and 68 healthy pregnant) between 18-45 years of age and between 24- 41 gestational weeks participated. Serum IMA levels were measured by the Albumin Cobalt Binding (ACB) test.

    Results

    The mean IMA values were found to be significantly higher in the preeclampsia group compared to the control group (p<0,001). Patients were divided into 3 groups; severe preeclampsia(n=29), non-severe preeclampsia(n=37) and healthy pregnant(n=68). Statistically significant difference was not found between severe preeclampsia and non-severe preeclampsia (p=0.505). The performance of IMA values in predicting the development of preeclampsia among all participants was evaluated with Receiver Operating Characteristic (ROC) analysis. According to the ROC analysis, the best cut-off value at which the maximum area under the curve (AUC) was obtained was found when IMA>0.98(AUC: 0.690 95% Confidence Interval (CI): 0.600-0.781 p<0.001). When IMA threshold value of >0.98 was taken to predict preeclampsia; the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated as 65.15%, 64.71%, 64.18%, and 65.67%, respectively.

    Conclusion

    IMA level may be a useful new marker in recognizing and predicting preeclampsia. However, despite the power of recognizing the disease, serum IMA levels do not give an idea about the severity of the disease. More comprehensive studies are needed in order to use IMA levels in the diagnosis of preeclampsia.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article

    Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo98

    Summary

    Original Article

    Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo98

    DOI 10.61622/rbgo/2024rbgo98

    Views155

    Abstract

    Objective

    To determine if maternal erythrocytosis is a risk factor for small-for-gestational age at term at 3,400-m altitude in pregnant women without intercurrent disease.

    Methods

    Analytical study of retrospective cohorts at Cusco, a city at 3,400-m altitude. Our participants were 224 and 483 pregnant women with and without exposure to maternal erythrocytosis, respectively. A logistic regression with the goodness of fit to the proposed model was also performed with the Hosmer and Lemeshow test, evaluating the small-for-gestational-age results with or without exposure to hemoglobin >14.5 g/dl.

    Results

    The incidence of small-for-gestational-age was 6.9% for this entire cohort. The maternal erythrocytosis during gestation without any maternal morbidity at 3,400-m altitude has an ORa=0.691 (p=0.271) for small-for-gestational-age at term. Inadequate prenatal control has an ORa=2.115 (p=0.016) for small-for-gestational-age compared to adequate prenatal control.

    Conclusion

    Maternal erythrocytosis in pregnant women without any morbidity is not a risk factor for small-for-gestational-age at 3,400 m-altitude.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article

    Therapeutic resources used by physiotherapists for the relief of labor pain: a cross-sectional study

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo99

    Summary

    Original Article

    Therapeutic resources used by physiotherapists for the relief of labor pain: a cross-sectional study

    Revista Brasileira de Ginecologia e Obstetrícia. 01-23-2025;47:e-rbgo99

    DOI 10.61622/rbgo/2024rbgo99

    Views148

    Abstract

    Objective

    The aim of the study was to identify non-pharmacological therapeutic resources used by physiotherapists for pain relief during labor and childbirth.

    Methods

    This is a cross-sectional study conducted from January to March 2021, followed the STROBE guidelines. It included Brazilian physiotherapists with a minimum of two years in obstetric care experience. Data were collected using a 33-item online questionnaire, which covered sociodemographic details and the utilization of non-pharmacological resources. Descriptive analysis was used to determine participant characteristics. Associations between sociodemographic variables, specialist titles, participation in scientific events, and methods for pain relief methods during childbirth were assessed using chi-square or Fisher’s exact tests. Data were analyzed using SPSS version 23.0, with a significance level set at 5% (p < 0.05).

    Results

    A total of 114 Brazilian physiotherapists participated in this study. Participants chose to utilize non-pharmacological therapies and resources that are within the scope of physiotherapists’ practice for labor pain. Kinesiotherapy with the use of devices was the most employed technique for pain relief during the birthing process.

    Conclusion

    The study highlights the prevalent use of non-pharmacological therapeutic resources, particularly kinesiotherapy with devices, among Brazilian physiotherapists for labor pain relief.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article

    Clinical, histopathological and immunohistochemical analysis of vulvar squamous cell carcinoma

    Revista Brasileira de Ginecologia e Obstetrícia. 12-04-2024;46:e-rbgo91

    Summary

    Original Article

    Clinical, histopathological and immunohistochemical analysis of vulvar squamous cell carcinoma

    Revista Brasileira de Ginecologia e Obstetrícia. 12-04-2024;46:e-rbgo91

    DOI 10.61622/rbgo/2024rbgo91

    Views119

    Abstract

    Objective:

    The average age of patients with vulvar squamous cell carcinoma (SCC) has been reported to have declined. Human papilloma virus (HPV)-related lesions have been shown to be associated with the expression of the immunohistochemical (IHC) marker p16. Non-HPV-related tumors have been characterized by p53 abnormal expression and PDL1 expression. We aimed to evaluate the correlation between these markers and vulvar SCC and to relate it to the clinical and pathological characteristics.

    Methods:

    Histopathologic assessments and IHC analyses of p16, p53, and PDL1 were performed in 41 samples of vulvar SCC collected between 2016 and 2021. The data were correlated with clinical and pathological characteristics of the patients.

    Results:

    The mean age of the patients was 72.1 years. Positive p16 and PDL1 staining was detected in 24.4% and 17.1% of the samples, respectively. p53 expression was negative in 19.5% of the samples, whereas it was overexpressed in 24.4%. p16-positive tumors showed a smaller depth of invasion (DOI) (p = 0.014), while tumors with p53 abnormal expression showed greater DOI (p = 0.041). PDL1 expression was correlated with increased number of inflammatory cells (p = 0.055). In addition, lesions with lymphovascular space invasion were p16-negative.

    Conclusion:

    In our sample, regarding to the SCC incidence the patients’ mean age did not change. The expression of p16 was inversely correlated with p53 results. Tumors with p53 abnormal expression and absence of p16 showed a greater DOI. Our data suggest an association between PDL1 expression and increased inflammatory infiltrates in vulvar SCC.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article

    Prevalence and factors associated with non-alcoholic fatty liver disease among women with polycystic ovary syndrome

    Revista Brasileira de Ginecologia e Obstetrícia. 12-04-2024;46:e-rbgo81

    Summary

    Original Article

    Prevalence and factors associated with non-alcoholic fatty liver disease among women with polycystic ovary syndrome

    Revista Brasileira de Ginecologia e Obstetrícia. 12-04-2024;46:e-rbgo81

    DOI 10.61622/rbgo/2024rbgo81

    Views150

    Abstract

    Objective:

    To verify the prevalence and factors associated with Non-Alcoholic Fatty Liver Disease (NAFLD) among women with Polycystic Ovary Syndrome (PCOS).

    Methods:

    A cross-sectional study was conducted with 53 patients with PCOS. The diagnosis of PCOS followed the Rotterdam criteria. The diagnosis of NAFLD was made through US showing hepatic steatosis, excluding significant alcohol consumption and chronic liver disease. The following variables were compared between the groups of women with and without NAFLD: age, race, anthropometric data, blood pressure levels, liver enzymes, glycemic and lipid profiles, total testosterone, presence of hirsutism, and metabolic syndrome (MS). Variables were compared between the groups using T-test, Mann-Whitney, and Chi-square tests.

    Results:

    Among 53 patients with PCOS, 50.9% had NAFLD. The NAFLD group had higher weight (p=0.003), BMI (p=0.001), waist circumference (p≤0.001), fasting glucose (p=0.021), HbA1C% (p=0.028), triglycerides (p=0.023), AST (p=0.004), ALT (p=0.001), higher prevalence of MS (p=0.004), and lower levels of HDL cholesterol (p=0.043). The other variables did not differ between the groups. Both groups were predominantly of caucasian race, and there was no significant difference in age.

    Conclusion:

    The prevalence of NAFLD among patients with PCOS was 50.9%. Metabolic and hepatic enzyme abnormalities were more prevalent in this group compared to the group without the disease. Obesity tripled the prevalence of NAFLD.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Original Article

    Prognosis and cardiotoxicity associated to adjuvant trastuzumab for breast cancer: real world study in a public health system

    Revista Brasileira de Ginecologia e Obstetrícia. 12-04-2024;46:e-rbgo93

    Summary

    Original Article

    Prognosis and cardiotoxicity associated to adjuvant trastuzumab for breast cancer: real world study in a public health system

    Revista Brasileira de Ginecologia e Obstetrícia. 12-04-2024;46:e-rbgo93

    DOI 10.61622/rbgo/2024rbgo93

    Views131

    Abstract

    Objective:

    To analyze the prognosis of patients with breast cancer who developed trastuzumab-induced cardiotoxicity and to analyze factors associated with and resulting from cardiotoxicity.

    Methods:

    This was a retrospective cohort study that included 255 HER2-positive breast cancer patients who received adjuvant trastuzumab therapy. The inclusion criteria were a diagnosis of HER2-positive breast cancer and adjuvant trastuzumab therapy; disease stage I-III; <70 years; and a baseline echocardiogram showing a left ventricular ejection fraction (LVEF) ≥ 55%. The Kaplan-Meier method, the log-rank test, and the Cox proportional hazards model were used.

    Results:

    In all, 15.3% (39/255) of patients presented with cardiotoxicity. Treatment was suspended in 92.3% (36/39) of patients who presented with cardiotoxicity during trastuzumab treatment. The treatment was suspended in 46 of 255 patients and it was permanently interrupted in 84.8% (33/46) of these patients, with 84.8% (28/33) due to cardiotoxicity. Cardiotoxicity was not associated with disease-free survival (DFS) (hazard ratio (HR) = 1.48; 95% confidence interval (CI = 0.79-2.78) or overall survival (OS) (HR = 1.68; 95%CI= 0.83-3.41). Patients with clinical stage III and whom trastuzumab therapy was suspended (all causes) had worse DFS; (HR = 3.19; 95% CI=1.77-5.74) and (HR = 1.83; 95% CI=1.01-3.32) respectively. Those with clinical stage III and whom trastuzumab therapy was permanently interrupted had worse OS; (HR = 3.80; 95% CI =1.82-7.94), and (HR = 2,26; 95% CI =1.09-4.68 respectively.

    Conclusion:

    Cardiotoxicity was not associated with DFS or OS. Clinical stage III, Suspension and permanent interruption of treatment regardless of the cause were associated with worse DFS and OS in breast cancer patients.

    See more
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Search

Search in:

Article type
Article type
abstract
book-review
brief-report
case-report
correction
editorial
letter
other
rapid-communication
research-article
review-article
Section
Section
Arigos Originais
Article
Artigo de Revisão
Original Articles
Carta ao Editor
Carta ao Editor
Carta ao Editor
Cartas
Cartas
Case Report
Case Reports
Caso e Tratamento
Clinical Consensus Recommendation
Corrigendum
Editoriais
Editorial
Editorial
Equipamentos e Métodos
Errata
Erratas
Erratas
Erratum
FEBRASGO POSITION STATEMENT
Febrasgo Statement
Febrasgo Statement Position
FIGO Statement
GUIDELINES
Integrative Review
Letter to Editor
Letter to the Editor
Métodos e Técnicas
Nominata 2024
Nota do Editor
Nota Prévia
Original Article
Original Article/Contraception
Original Article/Infertility
Original Article/Obstetrics
Original Article/Oncology
Original Article/Sexual Violence/Pediatric and Adolescent Gynecology
Original Article/Teaching and Training
Original Articles
Relato de Caso
Relato de Casos
Relatos de Casos
Reply to the Letter to the Editor
Resposta dos Autores
Resumo De Tese
Resumo De Tese
Resumos de Tese
Resumos de Tese
Resumos de Teses
Resumos de Teses
Resumos dos Trabalhos Premiados no 50º Congresso Brasileiro de Ginecologia e Obstetrícia
Review
Review Article
Review Articles
Revisão
Revisão
Short Communication
Special Article
Systematic Review
Técnica e Equipamentos
Técnicas e Equipamentos
Técnicas e Métodos
Trabalhos Originais
Trabalhos Originais
Year / Volume
Year / Volume
2025; v.47
2025; v.46
2024; v.46
2023; v.45
2022; v.44
2021; v.43
2020; v.42
2019; v.41
2018; v.40
2017; v.39
2016; v.38
2015; v.37
2014; v.36
2013; v.35
2012; v.34
2011; v.33
2010; v.32
2009; v.31
2008; v.30
2007; v.29
2006; v.28
2005; v.27
2004; v.26
2003; v.25
2002; v.24
2001; v.23
2000; v.22
1999; v.21
1998; v.20
ISSUE
ISSUE