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Original Article10-17-2000
Underreporting of maternal mortality in Campinas from 1992 to 1994
- Mary Angela Parpinelli,
- Aníbal Faúndes,
- José Guilherme Cecatti,
- Fernanda Garanhani de Castro Surita,
- Belmiro Gonçalves Pereira, [ … ],
- Eliana Amaral
Abstract
Original ArticleUnderreporting of maternal mortality in Campinas from 1992 to 1994
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(1):27-32
DOI 10.1590/S0100-72032000000100005
- Mary Angela Parpinelli,
- Aníbal Faúndes,
- José Guilherme Cecatti,
- Fernanda Garanhani de Castro Surita,
- Belmiro Gonçalves Pereira,
- Renato Passini Júnior,
- Eliana Amaral
Views154See morePurpose: to identify and quantify the underreporting of maternal mortality, from death certificates (DC) in Campinas, São Paulo, from 1992 to 1994. Methods: a total of 216 DC whose causes of death were maternal (declared and/or presumed) were selected among the 1032 DC of 10 to 49-year-old women. A complementary investigation was performed on hospital records, at the death verifying units, and in households. Results: eight additional maternal deaths were identified among the 204 DC with presumed maternal death. This corresponded to an underreporting rate of 40% or to a correction factor of 1.67 for the official MMR. The first cause of underreporting was abortion (71.5% or 05/07) and indirect maternal deaths represented the second cause (66.6% or 02/03). Conclusions: the death certificate cannot be considered the only source to identify maternal death. Complementary investigation of the presumable causes of maternal death should be performed. Legislation, social and religious factors might influence the underreporting of abortion as the cause of maternal death.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article10-17-2000
Gestational and delivery complications as perinatal risk factors
- Alfredo de Almeida Cunha,
- Aldo Franklin Ferreira Reis,
- Thales Pontes Luz,
- Tania Zdenka Guillén de Torres
Abstract
Original ArticleGestational and delivery complications as perinatal risk factors
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(1):19-26
DOI 10.1590/S0100-72032000000100004
- Alfredo de Almeida Cunha,
- Aldo Franklin Ferreira Reis,
- Thales Pontes Luz,
- Tania Zdenka Guillén de Torres
Views104See morePurpose: to evaluate gestational and delivery complications as risk factors for perinatal death. Methodology – Patients: the cases (perinatal deaths) were identified among a total of 3,031 deliveries from the maternity of the Rio de Janeiro State Military Police. Methods: the study design was a nested case-control one. Cases (n = 82) were perinatal deaths with a minimum gestational age of 28 weeks or a weight of 1,000 g. Controls (n = 246) were live babies for the first week of life. The analysis was made in three steps: univariate, stratified and multivariate (logistic regression). Results: the gestational complications showed an odds ratio of 4.21 and the delivery complications, 5.26. The newborn weight showed an OR = 0.999 per gram over 1,000 g weight. The gestational age showed an OR = 0.729 per week of gestation over 28 weeks. Conclusions: the gestational complications and the delivery complications were important risk factors for perinatal death. The gestational age and the weight of the newborn were important protective factors.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
10-13-2000
Avaliação da Mobilidade do Colo Vesical com Ultra-Sonografia Via Vaginal em Mulheres com Perda de Urina aos Esforços
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):387-387
Abstract
Avaliação da Mobilidade do Colo Vesical com Ultra-Sonografia Via Vaginal em Mulheres com Perda de Urina aos Esforços
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):387-387
DOI 10.1590/S0100-72032000000600014
Views46Avaliação da Mobilidade do Colo Vesical com Ultra-Sonografia Via Vaginal em Mulheres com Perda de Urina aos Esforços […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
10-13-2000
Estudo da associação entre parâmetros anatomopatológicos de prognóstico e a dopplerfluxometria no câncer de mama
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):387-388
Abstract
Estudo da associação entre parâmetros anatomopatológicos de prognóstico e a dopplerfluxometria no câncer de mama
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):387-388
DOI 10.1590/S0100-72032000000600015
Views59Estudo da associação entre parâmetros anatomopatológicos de prognóstico e a dopplerfluxometria no câncer de mama […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
10-13-2000
Análise crítica comparativa dos achados ultra-sonográficos, vídeo histeroscópicos e histológicos no diagnóstico das patologias endometriais
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):386-386
Abstract
Análise crítica comparativa dos achados ultra-sonográficos, vídeo histeroscópicos e histológicos no diagnóstico das patologias endometriais
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):386-386
DOI 10.1590/S0100-72032000000600012
Views51Análise crítica comparativa dos achados ultra-sonográficos, vídeo histeroscópicos e histológicos no diagnóstico das patologias endometriais […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
10-13-2000
Análise comparativa dos aspectos clínicos, laparoscópicos e histopatológicos da endometriose pélvica
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):386-387
Abstract
Análise comparativa dos aspectos clínicos, laparoscópicos e histopatológicos da endometriose pélvica
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):386-387
DOI 10.1590/S0100-72032000000600013
Views69Análise comparativa dos aspectos clínicos, laparoscópicos e histopatológicos da endometriose pélvica. […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
10-13-2000
Quimioterapia neoadjuvante para o tratamento de portadoras do câncer de colo uterino (EC II e III): avaliação clínica, laboratorial, imunológica, psicológica e ultra-somográfica, comparada ao índice de resposta
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):385-385
Abstract
Quimioterapia neoadjuvante para o tratamento de portadoras do câncer de colo uterino (EC II e III): avaliação clínica, laboratorial, imunológica, psicológica e ultra-somográfica, comparada ao índice de resposta
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):385-385
DOI 10.1590/S0100-72032000000600011
Views55Quimioterapia neoadjuvante para o tratamento de portadoras do câncer de colo uterino (EC II e III): avaliação clínica, laboratorial, imunológica, psicológica e ultra-somográfica, comparada ao índice de resposta […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
10-13-2000
Avaliação de fatores de risco para o desenvolvimento de complicações perinatais na presença de cardiopatia materna
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):385-385
Abstract
Avaliação de fatores de risco para o desenvolvimento de complicações perinatais na presença de cardiopatia materna
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):385-385
DOI 10.1590/S0100-72032000000600010
Views65Avaliação de fatores de risco para o desenvolvimento de complicações perinatais na presença de cardiopatia materna […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article03-27-2020
Gestational Diabetes in the Population Served by Brazilian Public Health Care. Prevalence and Risk Factors
- Pâmela Antoniazzi dos Santos
,
- José Mauro Madi
,
- Emerson Rodrigues da Silva
,
- Daiane de Oliveira Pereira Vergani
,
- Breno Fauth de Araújo
,
[ … ], - Rosa Maria Rahmi Garcia
Abstract
Original ArticleGestational Diabetes in the Population Served by Brazilian Public Health Care. Prevalence and Risk Factors
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):12-18
- Pâmela Antoniazzi dos Santos
,
- José Mauro Madi
,
- Emerson Rodrigues da Silva
,
- Daiane de Oliveira Pereira Vergani
,
- Breno Fauth de Araújo
,
- Rosa Maria Rahmi Garcia
Views368See moreAbstract
Objective
To assess the prevalence of gestational diabetes mellitus and the main associated risk factors in the population served by the Brazilian Unified Health System in the city of Caxias do Sul, state of Rio Grande do Sul.
Materials and Methods
A descriptive, cross-sectional and retrospective study was conducted. Maternal variables were collected from the medical records of all pregnant women treated at the basic health units in 2016. Hyperglycemia during pregnancy (pregestational diabetes, overt diabetes and gestational diabetes mellitus) was identified by analyzing the results of a 75-g oral glucose tolerance test, as recommended by the Brazilian Ministry of Health. Based on the data, the women were allocated into two groups: the gestational diabetes group and the no gestational diabetes group.
Results
The estimated prevalence of gestational diabetes among 2,313 pregnant women was of 5.4% (95% confidence interval [95%CI]: 4.56-6.45). Pregnant women with 3 or more pregnancies had twice the odds of having gestational diabetes compared with primiparous women (odds ratio [OR]=2.19; 95%CI: 1.42-3.37; p<0.001). Pregnant women aged 35 years or older had three times the odds of having gestational diabetes when compared with younger women (OR=3.01; 95%CI: 1.97-4.61; p<0.001). Overweight pregnant women were 84% more likely to develop gestational diabetes than those with a body mass index lower than 25 kg/m2 (OR =1.84; 95%CI: 1.25-2.71; p=0.002). A multivariable regression analysis showed that being overweight and being 35 years old or older were independent variables.
Conclusion
In this population, the prevalence of gestational diabetes mellitus was of 5.4%. Age and being overweight were predictive factors for gestational diabetes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Pâmela Antoniazzi dos Santos
-
Systematic Review05-01-2017
Zika Virus Infection in Pregnant Women and Microcephaly
- Geraldo Duarte,
- Antonio Fernandes Moron,
- Artur Timerman,
- César Eduardo Fernandes,
- Corintio Mariani Neto, [ … ],
- Rossana Pulcineli Vieira Francisco
Abstract
Systematic ReviewZika Virus Infection in Pregnant Women and Microcephaly
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(5):235-248
- Geraldo Duarte,
- Antonio Fernandes Moron,
- Artur Timerman,
- César Eduardo Fernandes,
- Corintio Mariani Neto,
- Gutemberg Leão de Almeida Filho,
- Heron Werner Junior,
- Hilka Flavia Barra do Espírito Santo,
- João Alfredo Piffero Steibel,
- João Bortoletti Filho,
- Juvenal Barreto Borriello de Andrade,
- Marcelo Burlá,
- Marcos Felipe Silva de Sá,
- Newton Eduardo Busso,
- Paulo César Giraldo,
- Renato Augusto Moreira de Sá,
- Renato Passini Junior,
- Rosiane Mattar,
- Rossana Pulcineli Vieira Francisco
Views409Abstract
From the discovery of the Zika virus (ZIKV) in 1947 in Uganda (Africa), until its arrival in South America, it was not known that it would affect human reproductive life so severely. Today, damagetothe central nervous system is known to be multiple, and microcephaly is considered the tip of the iceberg. Microcephaly actually represents the epilogue of this infection’s devastating process on the central nervous system of embryos and fetuses. As a result of central nervous system aggression by the ZIKV, this infection brings the possibility of arthrogryposis, dysphagia, deafness and visual impairment. All of these changes of varying severity directly or indirectly compromise the future life of these children, and are already considered a congenital syndrome linked to the ZIKV. Diagnosis is one of the main difficulties in the approach of this infection. Considering the clinical part, it has manifestations common to infections by the dengue virus and the chikungunya fever, varying only in subjective intensities. The most frequent clinical variables are rash, febrile state, non-purulent conjunctivitis and arthralgia, among others. In terms of laboratory resources, there are also limitations to the subsidiary diagnosis. Molecular biology tests are based on polymerase chain reaction (PCR)with reverse transcriptase (RT) action, since the ZIKV is a ribonucleic acid (RNA) virus. The RT-PCR shows serum or plasma positivity for a short period of time, no more than five days after the onset of the signs and symptoms. The ZIKVurine test is positive for a longer period, up to 14 days. There are still no reliable techniques for the serological diagnosis of this infection. If there are no complications (meningoencephalitis or Guillain-Barré syndrome), further examination is unnecessary to assess systemic impairment. However, evidence is needed to rule out other infections that also cause rashes, such as dengue, chikungunya, syphilis, toxoplasmosis, cytomegalovirus, rubella, and herpes. There is no specific antiviral therapy against ZIKV, and the therapeutic approach to infected pregnant women is limited to the use of antipyretics and analgesics. Anti-inflammatory drugs should be avoided until the diagnosis of dengue is discarded. There is no need to modify the schedule of prenatal visits for pregnant women infected by ZIKV, but it is necessary to guarantee three ultrasound examinations during pregnancy for low-risk pregnancies, and monthly for pregnant women with confirmed ZIKV infection. Vaginal delivery and natural breastfeeding are advised.
Key-words arbovirus infectionsblindness/ etiologydeafness/ etiologymicrocephaly/ ultrasonographyPregnancy complicationsReal-time polymerase chain reactionZika virusSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article06-27-2022
Polycystic Ovary Syndrome in Adolescence: Challenges in Diagnosis and Management
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(4):425-433
Abstract
Review ArticlePolycystic Ovary Syndrome in Adolescence: Challenges in Diagnosis and Management
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(4):425-433
Views434See moreAbstract
Diagnosing polycystic ovary syndrome (PCOS) during adolescence is challenging since normal pubertal development overlap typical features of this syndrome. The authors aim to summarize the existing evidence concerning PCOS in adolescence, particularly its diagnostic criteria and therapeutic options. A search throughout medical databases such as PubMed and MedScape was performed. Diagnostic criteria include irregular menstrual cycles according to time postmenarche and evidence of clinical hyperandrogenism and/or biochemical hyperandrogenism, provided other causes have been excluded. Polycystic ovarianmorphology ought not to be used as a diagnostic criterion. Treatment should targetmanifestations and/or comorbidities, even in the absence of a definite diagnosis. Lifestyle interventions are the first-line treatment. Combined oral contraceptives, metformin or antiandrogens may also be considered as adjuvants. Screening for PCOS in adolescence is crucial as it allows an early intervention on the symptoms and comorbidities presented leading to better long-term reproductive and metabolic outcomes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article05-01-2018
Uterine Artery Doppler in Screening for Preeclampsia and Fetal Growth Restriction
- Marianna Amaral Pedroso,
- Kirsten Rebecca Palmer,
- Ryan James Hodges,
- Fabricio da Silva Costa,
- Daniel Lorber Rolnik
Abstract
Review ArticleUterine Artery Doppler in Screening for Preeclampsia and Fetal Growth Restriction
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(5):287-293
- Marianna Amaral Pedroso,
- Kirsten Rebecca Palmer,
- Ryan James Hodges,
- Fabricio da Silva Costa,
- Daniel Lorber Rolnik
Views419See moreAbstract
Objective
To perform a comprehensive review of the current evidence on the role of uterine artery Doppler, isolated or in combination with other markers, in screening for preeclampsia (PE) and fetal growth restriction (FGR) in the general population. The review included recently published large cohort studies and randomized trials.
Methods
A search of the literature was conducted usingMedline, PubMed, MeSH and ScienceDirect. Combinations of the search terms “preeclampsia,” “screening,” “prediction,” “Doppler,” “Doppler velocimetry,” “fetal growth restriction,” “small for gestational age” and “uterine artery” were used. Articles in English (excluding reviews) reporting the use of uterine artery Doppler in screening for PE and FGR were included.
Results
Thirty articles were included. As a single predictor, uterine artery Doppler detects less than 50% of the cases of PE and no more than 40% of the pregnancies affected by FGR. Logistic regression-based models that allow calculation of individual risk based on the combination of multiple markers, in turn, is able to detect ~ 75% of the cases of preterm PE and 55% of the pregnancies resulting in small for gestational age infants.
Conclusion
The use of uterine artery Doppler as a single predictive test for PE and FGR has poor accuracy. However, its combined use in predictive models is promising, being more accurate in detecting preterm PE than FGR.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article09-16-2019
Do Women have Adequate Knowledge about Pelvic Floor Dysfunctions? A Systematic Review
- Júlia Ferreira Fante,
- Thais Daniel Silva,
- Elaine Cristine Lemes Mateus-Vasconcelos,
- Cristine Homsi Jorge Ferreira,
- Luiz Gustavo Oliveira Brito
Abstract
Review ArticleDo Women have Adequate Knowledge about Pelvic Floor Dysfunctions? A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(8):508-519
- Júlia Ferreira Fante,
- Thais Daniel Silva,
- Elaine Cristine Lemes Mateus-Vasconcelos,
- Cristine Homsi Jorge Ferreira,
- Luiz Gustavo Oliveira Brito
Views387See moreAbstract
Objective
We sought to investigate whether women present adequate knowledge of the main pelvic floor disorders (PFDs) (urinary incontinence – UI, fecal incontinence – FI, and pelvic organ prolapse – POP).
Data
sources A systematic review was performed in the MEDLINE, PEDro, CENTRAL, and Cochrane databases for publications from inception to April 2018. Selection of studies A total of 3,125 studies were reviewed. Meta-analysis was not possible due to the heterogeneity of primary outcomes and the diversity of instruments for measuring knowledge. The quality of the articles included in the analysis was evaluated with the Newcastle-Ottawa Scale (NOS) adapted for cross-sectional studies.
Data collection
Two authors performed data extraction into a standardized spreadsheet.
Data synthesis
Nineteen studies were included, comprising 11,512 women. About the methodological quality (NOS), most of the studies (n= 11) presented a total score of 6 out of 10. Validated questionnaires and designed pilot-tested forms were the most frequently used ways of assessing knowledge. Some studies were stratified by race, age, or group minorities. The most used questionnaire was the prolapse and incontinence knowledge questionnaire (PIKQ) (n= 5). Knowledge and/or awareness regarding PFD was low to moderate among the studies. Urinary incontinence was the most prevalent PFD investigated, and the most important risk factors associated with the lack of knowledge of the pelvic floor were: African-American ethnicity (n= 3), low educational level (n= 4), low access to information (n= 5) and socioeconomic status (n= 3).
Conclusion
Most women have a gap in the knowledge of pelvic floor muscle dysfunctions, do not understand their treatment options, and are not able to identify risk factors for these disorders.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article04-09-2024
Screening and prevention of preterm birth: how is it done in clinical practice?
- Roberta Bulsing dos Santos
,
- Janete Vettorazzi
,
- Marcos Wengrover Rosa
,
- Ellen Machado Arlindo
,
- Edimárlei Gonsales Valério
Abstract
Original ArticleScreening and prevention of preterm birth: how is it done in clinical practice?
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo32
- Roberta Bulsing dos Santos
,
- Janete Vettorazzi
,
- Marcos Wengrover Rosa
,
- Ellen Machado Arlindo
,
- Edimárlei Gonsales Valério
Views552Abstract
Objective:
To ascertain how screening for preterm birth is performed among obstetricians working in public and private practice in a middle-income country.
Methods:
Cross-sectional study of 265 obstetrician-gynecologists employed at public and private facilities. An online questionnaire was administered, with items designed to collect data on prematurity screening and prevention practices.
Results:
The mean age of respondents was 44.5 years; 78.5% were female, and 97.7% had completed a medical residency program. Universal screening (i.e., by ultrasound measurement of cervical length) was carried out by only 11.3% of respondents in public practice; 43% request transvaginal ultrasound if the manual exam is abnormal, and 74.6% request it in pregnant women with risk factors for preterm birth. Conversely, 60.7% of respondents in private practice performed universal screening. This difference in screening practices between public and private practice was highly significant (p < 0.001). Nearly all respondents (90.6%) reported prescribing vaginal progesterone for short cervix.
Conclusion:
In the setting of this study, universal ultrasound screening to prevent preterm birth was used by just over half of doctors in private practice. In public facilities, screening was even less common. Use of vaginal progesterone in cervical shortening was highly prevalent. There is an unmet need for formal protocols for screening and prevention of preterm birth in middle-income settings.
Key-words attitudes, practiceCervical length measurementgynecologistshealth knowledgeInfant, prematureobstetriciansPreterm birthPreventionScreeningsurveys and questionnairesSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Roberta Bulsing dos Santos
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Review Article01-23-2022
Efficacy of Hormonal and Nonhormonal Approaches to Vaginal Atrophy and Sexual Dysfunctions in Postmenopausal Women: A Systematic Review
- Ayane Cristine Alves Sarmento
,
- Ana Paula Ferreira Costa
,
- Juliana Lírio
,
- José Eleutério Jr
,
- Pedro Vieira Baptista
,
[ … ], - Ana Katherine Gonçalves
Abstract
Review ArticleEfficacy of Hormonal and Nonhormonal Approaches to Vaginal Atrophy and Sexual Dysfunctions in Postmenopausal Women: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(10):986-994
- Ayane Cristine Alves Sarmento
,
- Ana Paula Ferreira Costa
,
- Juliana Lírio
,
- José Eleutério Jr
,
- Pedro Vieira Baptista
,
- Ana Katherine Gonçalves
Views390See moreAbstract
Objective
To evaluate the efficacy of the hormonal and nonhormonal approaches to symptoms of sexual dysfunction and vaginal atrophy in postmenopausal women.
Data Sources
We conducted a search on the PubMed, Embase, Scopus, Web of Science, SciELO, the Cochrane Central Register of Controlled Trials (CENTRAL), and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases, as well as on clinical trial databases. We analyzed studies published between 1996 and May 30, 2020. No language restrictions were applied.
Selection of Studies
We selected randomized clinical trials that evaluated the treatment of sexual dysfunction in postmenopausal women.
Data Collection
Three authors (ACAS, APFC, and JL) reviewed each article based on its title and abstract. Relevant data were subsequently taken from the full-text article. Any discrepancies during the review were resolved by consensus between all the listed authors.
Data Synthesis
A total of 55 studies were included in the systematic review. The approaches tested to treat sexual dysfunction were as follows: lubricants and moisturizers (18 studies); phytoestrogens (14 studies); dehydroepiandrosterone (DHEA; 8 studies); ospemifene (5 studies); vaginal testosterone (4 studies); pelvic floor muscle exercises (2 studies); oxytocin (2 studies); vaginal CO2 laser (2 studies); lidocaine (1 study); and vitamin E vaginal suppository (1 study).
Conclusion
We identified literature that lacks coherence in terms of the proposed treatments and selected outcome measures. Despite the great diversity in treatment modalities and outcome measures, the present systematic review can shed light on potential targets for the treatment, which is deemed necessary for sexual dysfunction, assuming that most randomized trials were evaluated with a low risk of bias according to the Cochrane Collaboration risk of bias tool. The present review is registered with the International Prospective Register of Systematic Reviews (PROSPERO; CRD42018100488).
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Ayane Cristine Alves Sarmento
-
Original Article04-08-2022
Prevalence of Premenstrual Syndrome and Associated Factors Among Academics of a University in Midwest Brazil
- Ana Paula Rodrigues Rezende
,
- Fernanda Rassi Alvarenga
,
- Marcelo Ramos
,
- Débora Luiza Franken
,
- Juvenal Soares Dias da Costa
,
[ … ], - Vera Maria Vieira Paniz
Abstract
Original ArticlePrevalence of Premenstrual Syndrome and Associated Factors Among Academics of a University in Midwest Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):133-141
- Ana Paula Rodrigues Rezende
,
- Fernanda Rassi Alvarenga
,
- Marcelo Ramos
,
- Débora Luiza Franken
,
- Juvenal Soares Dias da Costa
,
- Marcos Pascoal Pattussi
,
- Vera Maria Vieira Paniz
Views385Abstract
Objective
To investigate the prevalence of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) in university students, the factors associated with PMS, the most prevalent symptoms, and the interference of symptoms in academic, family, social, and work activities.
Methods
This cross-sectional study included 1,115 university students aged ≥ 18 years from the University of Rio Verde, Goiás. Premenstrual syndrome and PMDD were identified using the Premenstrual Symptoms Screening Tool. Associations with sociodemographic, behavioral, reproductive, nutritional, and health factors were investigated using the Poisson regression.
Results
The prevalence of PMS was 46.9% (95% confidence interval [CI] 44.0-49.8), and of PMDD, 11.1% (95% CI 9.3-13.0). The most prevalent symptoms were physical, such as breast tenderness, bloating, e weight gain (73%); followed by psychological ones such as overeating/food cravings, tearful/more sensitive to rejection (> 60%). More than 30% of the patients reported that the symptoms interfered in a moderate-tosevere way in their social and academic activities. After adjusted analysis, PMS was more prevalent in those who were attending the 1st/2nd semester of college (prevalence ratio [PR] 1.44; 95% CI 1.14-1.80), those who consumed alcohol in the last 30 days (PR 1.23; 95% CI 1.04-1.47), and those who had depression (PR 1.49; 95% CI 1.30-1.71).
Conclusion
Almost half of the university students had PMS and ~ 11%, PMDD. Physical symptoms were themost common and interfered in amoderate-to-severe way in various aspects of life. Attending the first semesters, consuming alcohol, and having depression were risk factors for PMS. The identification of risk factors for PMS is essential to prevent symptoms and reduce the impact of the syndrome.
Key-words Cross-sectional studiespremenstrual dysphoric disorderPremenstrual syndromeRisk factorsStudentsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Ana Paula Rodrigues Rezende
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FEBRASGO POSITION STATEMENT06-27-2019
Pre-eclampsia/Eclampsia
- José Carlos Peraçoli
,
- Vera Therezinha Medeiros Borges,
- José Geraldo Lopes Ramos,
- Ricardo de Carvalho Cavalli,
- Sérgio Hofmeister de Almeida Martins Costa, [ … ],
- Edson Viera da Cunha Filho
Abstract
FEBRASGO POSITION STATEMENTPre-eclampsia/Eclampsia
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):318-332
- José Carlos Peraçoli
,
- Vera Therezinha Medeiros Borges,
- José Geraldo Lopes Ramos,
- Ricardo de Carvalho Cavalli,
- Sérgio Hofmeister de Almeida Martins Costa,
- Leandro Gustavo de Oliveira,
- Francisco Lazaro Pereira de Souza,
- Henri Augusto Korkes,
- Ione Rodrigues Brum,
- Maria Laura Costa,
- Mário Dias Corrêa Junior,
- Nelson Sass,
- Angélica Lemos Debs Diniz,
- Caio Antonio de Campos Prado,
- Edson Viera da Cunha Filho
Views119See moreAbstract
Pre-eclampsia is a multifactorial and multisystemic disease specific to gestation. It is classically diagnosed by the presence of hypertension associated with proteinuria manifested in a previously normotensive pregnant woman after the 20th week of gestation. Pre-eclampsia is also considered in the absence of proteinuria if there is target organ damage. The present review takes a general approach focused on aspects of practical interest in the clinical and obstetric care of these women. Thus, it explores the still unknown etiology, current aspects of pathophysiology and of the diagnosis, the approach to disease prediction, its adverse outcomes and prevention. Management is based on general principles, on nonpharmacological and on pharmacological clinical treatment of severe or nonsevere situations with emphasis on the hypertensive crisis and eclampsia. Obstetric management is based on preeclampsia without or with signs of clinical and/or laboratory deterioration, stratification of gestational age
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - José Carlos Peraçoli
-
Systematic Review05-01-2017
Zika Virus Infection in Pregnant Women and Microcephaly
- Geraldo Duarte,
- Antonio Fernandes Moron,
- Artur Timerman,
- César Eduardo Fernandes,
- Corintio Mariani Neto, [ … ],
- Rossana Pulcineli Vieira Francisco
Abstract
Systematic ReviewZika Virus Infection in Pregnant Women and Microcephaly
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(5):235-248
- Geraldo Duarte,
- Antonio Fernandes Moron,
- Artur Timerman,
- César Eduardo Fernandes,
- Corintio Mariani Neto,
- Gutemberg Leão de Almeida Filho,
- Heron Werner Junior,
- Hilka Flavia Barra do Espírito Santo,
- João Alfredo Piffero Steibel,
- João Bortoletti Filho,
- Juvenal Barreto Borriello de Andrade,
- Marcelo Burlá,
- Marcos Felipe Silva de Sá,
- Newton Eduardo Busso,
- Paulo César Giraldo,
- Renato Augusto Moreira de Sá,
- Renato Passini Junior,
- Rosiane Mattar,
- Rossana Pulcineli Vieira Francisco
Views409Abstract
From the discovery of the Zika virus (ZIKV) in 1947 in Uganda (Africa), until its arrival in South America, it was not known that it would affect human reproductive life so severely. Today, damagetothe central nervous system is known to be multiple, and microcephaly is considered the tip of the iceberg. Microcephaly actually represents the epilogue of this infection’s devastating process on the central nervous system of embryos and fetuses. As a result of central nervous system aggression by the ZIKV, this infection brings the possibility of arthrogryposis, dysphagia, deafness and visual impairment. All of these changes of varying severity directly or indirectly compromise the future life of these children, and are already considered a congenital syndrome linked to the ZIKV. Diagnosis is one of the main difficulties in the approach of this infection. Considering the clinical part, it has manifestations common to infections by the dengue virus and the chikungunya fever, varying only in subjective intensities. The most frequent clinical variables are rash, febrile state, non-purulent conjunctivitis and arthralgia, among others. In terms of laboratory resources, there are also limitations to the subsidiary diagnosis. Molecular biology tests are based on polymerase chain reaction (PCR)with reverse transcriptase (RT) action, since the ZIKV is a ribonucleic acid (RNA) virus. The RT-PCR shows serum or plasma positivity for a short period of time, no more than five days after the onset of the signs and symptoms. The ZIKVurine test is positive for a longer period, up to 14 days. There are still no reliable techniques for the serological diagnosis of this infection. If there are no complications (meningoencephalitis or Guillain-Barré syndrome), further examination is unnecessary to assess systemic impairment. However, evidence is needed to rule out other infections that also cause rashes, such as dengue, chikungunya, syphilis, toxoplasmosis, cytomegalovirus, rubella, and herpes. There is no specific antiviral therapy against ZIKV, and the therapeutic approach to infected pregnant women is limited to the use of antipyretics and analgesics. Anti-inflammatory drugs should be avoided until the diagnosis of dengue is discarded. There is no need to modify the schedule of prenatal visits for pregnant women infected by ZIKV, but it is necessary to guarantee three ultrasound examinations during pregnancy for low-risk pregnancies, and monthly for pregnant women with confirmed ZIKV infection. Vaginal delivery and natural breastfeeding are advised.
Key-words arbovirus infectionsblindness/ etiologydeafness/ etiologymicrocephaly/ ultrasonographyPregnancy complicationsReal-time polymerase chain reactionZika virusSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article02-01-2019
Syphilis in Pregnancy: The Reality in a Public Hospital
- Rafael Garcia Torres,
- Ana Laura Neves Mendonça,
- Grazielle Cezarine Montes,
- Jacqueline Jácome Manzan,
- João Ulisses Ribeiro, [ … ],
- Marina Carvalho Paschoini
Abstract
Original ArticleSyphilis in Pregnancy: The Reality in a Public Hospital
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(2):90-96
- Rafael Garcia Torres,
- Ana Laura Neves Mendonça,
- Grazielle Cezarine Montes,
- Jacqueline Jácome Manzan,
- João Ulisses Ribeiro,
- Marina Carvalho Paschoini
Views316See moreAbstract
Objective:
The present study assessed epidemiological and obstetrical data from pregnant women with syphilis at the Hospital de Clínicas of the Universidade Federal do Triângulo Mineiro (UFTM, in the Portuguese acronym), describing this disease during pregnancy and its vertical transmission for future healthcare actions.
Methods:
Records from pregnant women who had been admitted to the Obstetrics Department of the Hospital de Clínicas of the UFTM and were diagnosed with syphilis between 2007 and 2016 were reviewed. A standardized form was used to collect epidemiological, obstetric data and outcomes of congenital infection. The present research has been authorized by the Ethics Committee of the institution.
Results:
There were 268 women diagnosed with syphilis, with an average age of 23.6 years old. The majority of the patients were from Uberaba. Inadequate prenatal care was observed in 37.9% of the pregnant women. Only 34.2% of the patients completed the treatment according to the guidelines issued by the Ministry of Health of Brazil, and 19.8% of the partners of the patients underwent adequate syphilis treatment; 37 (13.8%) couples (patients and partners) underwent correct treatment. Regarding the obstetric outcomes, 4 (1.5%) patients had a miscarriage and 8 (3.4%) had fetal losses (from the fetal loss group, 7 had no adequate treatment); 61 (25.9%) patients had premature births – this prematurity has been significantly correlated to inadequate or incomplete treatment in 49 (27.9%) patients, compared with 12 (13.0%) patients with premature births and adequate treatment (p = 0.006). The average live newborn weight was 2,840 g; 25.3% had a birth weight < 2,500 g; 74.2% had congenital syphilis, a data with heavy correlation to inadequate or incomplete prenatal care, prematurity, and low birth weight.
Conclusion:
Public awareness policies on adequate prenatal care, intensification of serological screening, and early treatment of syphilis are needed, considering the rise of cases diagnosed during gestation and its potentially preventable deleterious consequences related to congenital transmission.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Editorial09-25-2020
COVID-19 and Maternal Death in Brazil: An Invisible Tragedy
- Marcos Nakamura-Pereira
,
- Melania Maria Ramos Amorim
,
- Rodolfo de Carvalho Pacagnella
,
- Maira Libertad Soligo Takemoto
,
- Fatima Cristina Cunha Penso
,
[ … ], - Maria do Carmo Leal
Abstract
EditorialCOVID-19 and Maternal Death in Brazil: An Invisible Tragedy
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(8):445-447
- Marcos Nakamura-Pereira
,
- Melania Maria Ramos Amorim
,
- Rodolfo de Carvalho Pacagnella
,
- Maira Libertad Soligo Takemoto
,
- Fatima Cristina Cunha Penso
,
- Jorge de Rezende-Filho
,
- Maria do Carmo Leal
Views246The infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for causing the coronavirus disease 2019 (COVID-19), became a devastating threat to the health of the world population and was declared a global pandemic by the World Health Organization (WHO) on March 11, 2020. Beginning in China at the end […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Marcos Nakamura-Pereira
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Original Article01-01-2018
Premenstrual Syndrome Diagnosis: A Comparative Study between the Daily Record of Severity of Problems (DRSP) and the Premenstrual Symptoms Screening Tool (PSST)
- Aline Henz,
- Charles Francisco Ferreira,
- Carolina Leão Oderich,
- Carin Weirich Gallon,
- Juliana Rintondale Sodré de Castro, [ … ],
- Maria Celeste Osório Wender
Abstract
Original ArticlePremenstrual Syndrome Diagnosis: A Comparative Study between the Daily Record of Severity of Problems (DRSP) and the Premenstrual Symptoms Screening Tool (PSST)
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(1):20-25
- Aline Henz,
- Charles Francisco Ferreira,
- Carolina Leão Oderich,
- Carin Weirich Gallon,
- Juliana Rintondale Sodré de Castro,
- Maiara Conzatti,
- Marcelo Pio de Almeida Fleck,
- Maria Celeste Osório Wender
Views512Abstract
Objective
To validate the premenstrual symptoms screening tool (PSST) in relation to the daily record of severity of problems (DRSP) for premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) diagnoses.
Methods
A cross-sectional study with 127 women (20 45 years) with PMS complaints. The women were evaluated in terms of weight, height and body mass index (BMI). After using the primary care evaluation of mental disorders (PRIME-MD) questionnaire to exclude the diagnosis of depression, the PSST was completed and the women were instructed to fill out the DRSP for two consecutive menstrual cycles. The agreement between the two questionnaires was assessed by the Kappa (k) and the prevalence-adjusted, bias-adjusted kappa (PABAK) values.
Results
Two-hundred and eighty-two women met the eligibility criteria and answered the PSST. The DRSP was completed for two cycles by 127 women. The percentages of women with PMS and PMDD diagnoses by the DRSP were 74.8% and 3.9% respectively; by PSST, the percentages were41.7% and 34.6% respectively. The number of patients considered “normal” (with symptoms below the threshold for the diagnosis of PMS) was similar in both questionnaires. There was no agreement (Kappa = 0.12) in the results of PMS/ PMDD diagnosis (the PABAK coefficient confirmed this result = 0.39). The PSST had a high sensitivity (79%) and a low specificity (33.3%) for PMS/PMDD diagnosis.
Conclusion
The PSST should be considered a diagnostic screening tool. Positive PMS/PMDD cases by PSST should be further evaluated by DRSP to confirm the diagnosis.
Key-words Diagnosispremenstrual dysphoric disorderPremenstrual syndromeQuestionnaireSigns and symptomsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article04-01-2017
Influence of Body Image in Women Undergoing Treatment for Breast Cancer
- Ana Carolina Lagos Prates,
- Ruffo Freitas-Junior,
- Mariana Ferreira Oliveira Prates,
- Márcia de Faria Veloso,
- Norami de Moura Barros
Abstract
Original ArticleInfluence of Body Image in Women Undergoing Treatment for Breast Cancer
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):175-183
- Ana Carolina Lagos Prates,
- Ruffo Freitas-Junior,
- Mariana Ferreira Oliveira Prates,
- Márcia de Faria Veloso,
- Norami de Moura Barros
Views303See moreAbstract
Objective
The objective of this study was to investigate the self-esteem of women with and without breast cancer regarding their body image.
Methods
A quantitative, case-control study in which 90 women with breast cancer were evaluated in the case group, and 77 women without breast cancer in the control group. For data collection, the body satisfaction scale (BSS), a scale adapted and validated in Brazil, and the Rosenberg self-esteem questionnaire were used. For the statistical analysis of the data, the Statistical Package for the Social Sciences software (IBM-SPSS, Chicago, Il, US), version 16.0 was used.
Results
Compared with the women without breast cancer, those with breast cancer were more dissatisfied with body image related to appearance. Women undergoing neoadjuvant chemotherapy were more dissatisfied with their appearance compared with those with cancer who were not undergoing this treatment. Mastectomy also accounted for more dissatisfaction concerning appearance among women who underwent the procedure compared with the women who were submitted to breast-conserving therapy.
Conclusion
Women with breast cancer were more dissatisfied with their body image compared with those without breast cancer, particularly following mastectomy or during chemotherapy. The self-esteem was found to be negatively affected in patients who were dissatisfied with their body image.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article07-01-2017
Abnormal Uterine Bleeding
- Cristina Laguna Benetti-Pinto,
- Ana Carolina Japur de Sá Rosa-e-Silva,
- Daniela Angerame Yela,
- José Maria Soares Júnior
Abstract
Review ArticleAbnormal Uterine Bleeding
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(7):358-368
- Cristina Laguna Benetti-Pinto,
- Ana Carolina Japur de Sá Rosa-e-Silva,
- Daniela Angerame Yela,
- José Maria Soares Júnior
Views346Abstract
Abnormal uterine bleeding is a frequent condition in Gynecology. It may impact physical, emotional sexual and professional aspects of the lives of women, impairing their quality of life. In cases of acute and severe bleeding, women may need urgent treatment with volumetric replacement and prescription of hemostatic substances. In some specific cases with more intense and prolonged bleeding, surgical treatment may be necessary. The objective of this chapter is to describe the main evidence on the treatment of women with abnormaluterinebleeding, both acuteand chronic.Didactically,thetreatmentoptions were based on the current International Federation of Gynecology and Obstetrics (FIGO) classification system (PALM-COEIN). The etiologies of PALM-COEIN are: uterine Polyp (P), Adenomyosis (A), Leiomyoma (L), precursor and Malignant lesions of the uterine body (M), Coagulopathies (C), Ovulatory dysfunction (O), Endometrial dysfunction (E), Iatrogenic (I), and Not yet classified (N). The articles were selected according to the recommendation grades of the PubMed, Cochrane and Embase databases, and those in which the main objective was the reduction of uterine menstrual bleeding were included. Only studies written in English were included. All editorial or complete papers that were not consistent with abnormal uterine bleeding, or studies in animal models, were excluded. The main objective of the treatment is the reduction of menstrual flow and morbidity and the improvement of quality of life. It is important to emphasize that the treatment in the acute phase aims to hemodynamically stabilize the patient and stop excessive bleeding, while the treatment in the chronic phase is based on correcting menstrual dysfunction according to its etiology and clinical manifestations. The treatment may be surgical or pharmacological, and thelatterisbasedmainlyonhormonaltherapy,anti-inflammatorydrugsandantifibrinolytics.
Key-words Abnormal uterine bleedingdysfunctional uterine bleedingheavy menstrual bleedingmenorrhagiaPALM-COEINSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article11-01-2018
Obstetric Outcomes among Syrian Refugees: A Comparative Study at a Tertiary Care Maternity Hospital in Turkey
- Sule Ozel,
- Selen Yaman,
- Hatice Kansu-Celik,
- Necati Hancerliogullari,
- Nurgul Balci, [ … ],
- Yaprak Engin-Ustun
Abstract
Original ArticleObstetric Outcomes among Syrian Refugees: A Comparative Study at a Tertiary Care Maternity Hospital in Turkey
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(11):673-679
- Sule Ozel,
- Selen Yaman,
- Hatice Kansu-Celik,
- Necati Hancerliogullari,
- Nurgul Balci,
- Yaprak Engin-Ustun
Views205See moreAbstract
Objective
The aim of this study was to analyze and compare obstetric and neonatal outcomes between Syrian refugees and ethnic Turkish women.
Methods
Retrospective, observational study. A total of 576 Syrian refugees and 576 ethnic Turkish women were included in this study, which was conducted between January 2015 and December 2015 at a tertiary maternity training hospital in Ankara, Turkey. The demographic characteristics, obstetric and neonatal outcomes were compared. The primary outcomes were pregnancy outcomes and cesarean rates between the groups
Results
The mean age was significantly lower in the refugee group (p< 0.001). Mean gravidity, proportion of adolescent pregnancies, proportion of pregnant women aged 12 to 19 years, and number of pregnancies at < 18 years were significantly higher among the refugee women (p< 0.001). Rates of antenatal follow-up, double testing, triple testing, gestational diabetes mellitus (GDM) screening, and iron replacement therapy were significantly lower in the refugee group (p< 0.001). The primary Cesarean section rate was significantly lower in the refugee group (p= 0.034). Pregnancies in the refugee group were more complicated, with higher rates of preterm delivery (< 37 weeks), preterm premature rupture of membranes (PPROM), and low birth weight (< 2,500 g) when compared with the control group (4.2% versus 0.7%, p< 0.001; 1.6% versus 0.2%, p= 0.011; and 12% versus 5.8%, p< 0.001, respectively). Low education level (odds ratio [OR] = 1.7, 95% confidence interval [CI] = 0.5–0.1), and weight gain during pregnancy (OR = 1.7, 95% CI = 0.5–0.1) were found to be significant indicators for preterm birth/PPROM and low birthweight.
Conclusion
Syrian refugees had increased risks of certain adverse obstetric outcomes, including preterm delivery, PPROM, lower birth weight, and anemia. Several factors may influence these findings; thus, refugee women would benefit from more targeted care during pregnancy and childbirth.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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