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Original Article04-09-1998
Clinicopathologic Analysis of Vulvar Intraepithelial Neoplasia: review of 46 Cases
- Luiz Antonio Verdiani,
- Cássia Raquel Teatin Juliato,
- Sophie F. Mauricette Derchain,
- Júlio Eduardo Ferro
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleClinicopathologic Analysis of Vulvar Intraepithelial Neoplasia: review of 46 Cases
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):371-376
DOI 10.1590/S0100-72031998000700001
- Luiz Antonio Verdiani,
- Cássia Raquel Teatin Juliato,
- Sophie F. Mauricette Derchain,
- Júlio Eduardo Ferro
Views142See moreThe purpose of the present study was to evaluate some epidemiological, clinical and pathological characteristics of the different grades of vulvar intraepithelial neoplasia (VIN), and its relation with the presence of human papillomavirus (HPV). The charts of 46 women with VIN, examined from 1986 through 1997, were reviewed. For statistical analysis the chi² with yates correction when appropriate, and Fisher’s exact tests were used. Regarding the grade of VIN, six women presented VIN 1, six others had VIN 2 and the remaining 34 presented VIN 3. All women presented similar characteristics such as age, menstrual status and age at first sexual intercourse. Women with more than one lifetime sexual partner had a tendency to show more VIN 3 (p = 0.090). Cigarette smoking was significantly associated with the severity of the vulvar lesion (p = 0.031). HPV was significantly more frequent in women younger than 35 years of age (p = 0.005) and in women with multiple lesions (p = 0.089). Although the number of lesions were not related to the severity of VIN (p = 0.703), lesions with extensions greater than 2 cm were significantly associated with VIN 3 (p = 0.009). The treatment of choice for VIN 3 was surgery, including local resection and simple vulvectomy. Eight women relapsed, and only one had VIN 2. We concluded that among women with VIN, cigarette smoking and more than one lifetime sexual partner were associated with high-grade lesions. HPV was more frequent among patients younger than 35 years of age presenting multiple lesions. Women with VIN 3 presented lesions bigger than 2 cm and a high relapse rate, despite the type of treatment applied.
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Original Article04-05-1998
Estimation of Fetal Weight: Comparison Between a Clinical Method and Ultrasonography
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):551-555
Views99This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleEstimation of Fetal Weight: Comparison Between a Clinical Method and Ultrasonography
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):551-555
DOI 10.1590/S0100-72031998001000002
Views99See morePurpose: to assess the validity of fetal weight estimation by a method based on uterine height — Johnson’s rule. Methods: one hundred and one pregnant women and their newborn children were studied. The fetal weight was estimated using an adaptation of Johnson’s rule, which consists of the clinical application of a mathematical model to calculate the fetal weight based on the uterine height and the height of fetal presentation. The estimated weight was obtained on the day of delivery and was compared to the weight observed after birth. This, in turn, was the control of the analysis of validity of the method used. On the same date, a detailed obstetrical ultrasonography (US) was conducted which included the fetal weight, calculated by the use of Sheppard’s tables. This weight, estimated by US, was compared to the birth weight. Results: the results have proven that the clinical estimate used in this study has a similar value to that of the US calculation of birth weight. The accuracy of the clinical method, with variations of 5%, 10% and 15% between estimated and observed weights, was 55.3%, 73% and 86.7%, respectively. Those of the US were 60.7%, 75.4% and 91.1%, respectively. When comparing both sets of figures, values were not different from a statistical standpoint. Conclusion: the clinical evaluation has shown to be accurate, similarly to the US, when calculating the birth weight.
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04-05-1998
Indice de líquido amniótico em gestantes diabéticas e a qualidade do controle glicêmico na gestação
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
Abstract
Indice de líquido amniótico em gestantes diabéticas e a qualidade do controle glicêmico na gestação
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
DOI 10.1590/S0100-72031998000800011
Views59Indice de Líquido Amniótico em Gestantes Diabéticas e a Qualidade do Controle Glicêmico na Gestação.[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
04-05-1998
Avaliação do grau nuclear da célula maligna da mama como parâmetro de atividade proliferativa tumoral: comparação com a expressão do antígeno nuclear de proliferação celular (PCNA/ciclina)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
Abstract
Avaliação do grau nuclear da célula maligna da mama como parâmetro de atividade proliferativa tumoral: comparação com a expressão do antígeno nuclear de proliferação celular (PCNA/ciclina)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):485-485
DOI 10.1590/S0100-72031998000800010
Views65Avaliação do Grau Nuclear da Célula Maligna da Mama como Parâmetro de Atividade Proliferativa Tumoral: Comparação com a Expressão do Antígeno Nuclear de Proliferação Celular (PCNA/ciclina).[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Case Report04-05-1998
Prenatal diagnosis of arthrogryposis multiplex congenita: a case report
- Carlos Augusto Alencar Júnior,
- Francisco Edson de Lucena Feitosa,
- Mac Gontei,
- Sammya Bezerra Maia,
- Dalgimar Beserra de Meneses
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Case ReportPrenatal diagnosis of arthrogryposis multiplex congenita: a case report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):481-484
DOI 10.1590/S0100-72031998000800009
- Carlos Augusto Alencar Júnior,
- Francisco Edson de Lucena Feitosa,
- Mac Gontei,
- Sammya Bezerra Maia,
- Dalgimar Beserra de Meneses
Views84See moreArthrogryposis multiplex congenita is characterized by multiple joint contractures present at birth. Prenatal diagnosis is difficult. There are few reports in the literature. Fetal akinesia, abnormal limb position, intrauterine growth retardation, and polyhydramnios are the main findings of the ultrasonographic diagnosis. The authors describe a case of arthrogryposis multiplex congenita ultrasonographically diagnosed in the third gestational trimester. The main findings were absence of fetal movements, polyhydramnios, symmetrical and non-symmetrical fetal growth retardation with marked decrease of abdominal and thoracic circumference, low-set ears, micrognathia, continuous flexure contracture of limbs, internal rotation of the femur, and clubfoot on the right.
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Original Article04-05-1998
Screening of breast cancer metastasis at preoperative work-up
- Maria Bethânia da Costa Chein,
- Luciane Maria Oliveira Brito,
- Simão Rotstein,
- Luiz Henrique Gebrim,
- Aldo Franklin F Reis, [ … ],
- Luciana Dessen Padilha
Views123This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleScreening of breast cancer metastasis at preoperative work-up
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):475-479
DOI 10.1590/S0100-72031998000800008
- Maria Bethânia da Costa Chein,
- Luciane Maria Oliveira Brito,
- Simão Rotstein,
- Luiz Henrique Gebrim,
- Aldo Franklin F Reis,
- Luciana Dessen Padilha
Views123See morePurpose: to analyze the frequency of preoperative bilateral synchronic cancer and occult metastases in 454 operable breast cancer patients, at Instituto Nacional de Câncer (Brazil). Methods: the preoperative evaluation consisted of mammography, bone scan with X-ray if necessary, and chest X-ray. 260 (57.3 %) of 454 patients underwent liver echography. We calculated the cost X effectiveness ratio considering only the direct costs (monetary value) and the effectiveness was analyzed based on the number of metastases identifid by the screening tests. Results: we did not find any case of bilateral synchronic cancer, and the frequency of patients with metastasis was 2% (9/454). The diagnosis of bone metastasis was 1.5 % (7/454). The percentage of lung (2/454) and liver (1/260) metastasis was the same, 0.4 %. Most of the patients with metastases were in stage IIIb (44.5 %). The results of the screening tests showed the alteration of the initial clinical stage in 9 patients only (2%). The total cost of the screening tests for the diagnosis of systemic disease in 9 patients, was US$ 131,020.00. The cost of each diagnosed metastasise, for a total of 10 (two were found in one of the patients), was US$ 29,221.85 and the cost/effectiveness ratio was 22.3%. Conclusious: the results showed that screening for metastases in the preoperative clinical staging of breast cancer should be limited to patients symptomatic for systemic disease or in clinical stage III and that the cost/effectiveness ratio of the tests demonstrated a reduced benefit in the preoperative evaluation.
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Original Article04-05-1998
Second-degree family history as a risk factor for breast cancer
- Rafael Marques de Souza,
- Anderson Rech Lazzaron,
- Rafael Defferrari,
- Álvaro A. Borba,
- Luciana Scherer, [ … ],
- Antônio L. Frasson
Views127This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleSecond-degree family history as a risk factor for breast cancer
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):469-473
DOI 10.1590/S0100-72031998000800007
- Rafael Marques de Souza,
- Anderson Rech Lazzaron,
- Rafael Defferrari,
- Álvaro A. Borba,
- Luciana Scherer,
- Antônio L. Frasson
Views127See morePurpose: to evaluate the association between second-degree family history of breast cancer and the risk to develop the disease. Methods: case-control study of incident cases. Sixty-six incident breast cancer cases and 198 controls were selected among women who were submitted to mammography in a private clinic between January 1994 and July 1997. Cases and controls were paired regarding age, age at menarche, at first live birth, at menopause, parity, oral contraceptives and use of hormonal replacement therapy. Results: there was no significant difference between cases and controls regarding all risk factors evaluated, besides second-degree family history. Patients with breast cancer were more likely to have second-degree relatives with breast cancer when compared to controls (OR=2.77; 95% CI, 1.03-7.38; p=0.039). Conclusions: malignant neoplasm of the breast is significantly associated with a second-degree family history of this disease.
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Original Article04-05-1998
Fine needle aspiration biopsy: performance in the differential diagnosis of palpable breast masses
- Orlando José de Almeida,
- Marcelo Alvarenga,
- José Guilherme Cecatti,
- Jessé de Paula Neves Jorge,
- Júlia Kawamura Tambascia
Abstract
Original ArticleFine needle aspiration biopsy: performance in the differential diagnosis of palpable breast masses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(8):463-467
DOI 10.1590/S0100-72031998000800006
- Orlando José de Almeida,
- Marcelo Alvarenga,
- José Guilherme Cecatti,
- Jessé de Paula Neves Jorge,
- Júlia Kawamura Tambascia
Views63See morePurpose: to evaluate, in a prospective way, the performance of the fine needle aspiration biopsy in the differential diagnosis of palpable breast masses. Method: the sensitivity, specificity, positive and negative predictive values for this test were evaluated in 102 women with age above 30 years and a palpable breast mass, who were attended at the University of Campinas. All punctures were performed by the same examiner. Results: the procedure had a sensitivity of 97%, specificity of 87%, positive predictive value of 94% and negative predictive value of 93%. The insufficient or unsatisfactory sample rate was 16% for the first aspiration, decreasing to 2% with a new procedure. Conclusions: this test showed to be highly sensitive and specific for the differential diagnosis of palpable breast masses, reassuring its great importance for the clinical approach of palpable masses.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article01-23-2011
Impact of physical activity on quality of life in middle-aged women: a population based study
- Ana Katherine da Silveira Gonçalves,
- Ana Carla Gomes Canário,
- Patrícia Uchôa Leitão Cabral,
- Rayanna Assunção Henrique da Silva,
- Maria Helena Constantino Spyrides, [ … ],
- José Eleutério Jr
Views89This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleImpact of physical activity on quality of life in middle-aged women: a population based study
Revista Brasileira de Ginecologia e Obstetrícia. 2011;33(12):408-413
DOI 10.1590/S0100-72032011001200006
- Ana Katherine da Silveira Gonçalves,
- Ana Carla Gomes Canário,
- Patrícia Uchôa Leitão Cabral,
- Rayanna Assunção Henrique da Silva,
- Maria Helena Constantino Spyrides,
- Paulo César Giraldo,
- José Eleutério Jr
Views89See morePURPOSE: To evaluate the influence of physical activity on the quality of life of middle-aged women. METHODS: A population-based cross-sectional study was conducted on 370 women aged 40 to 65 years-old recruited from a population-based sample. Enrollment took place in Basic Health Units in each health district of the city (North, South, East, and West) from June to September 2011. According to the Municipal Health Department of the City, 20,801 women were assisted at the Basic Health Units during a one-year period. The sample size calculation was stratified by district and based on a 95% confidence level with a power of 80%, as well as an error estimate of 5% and it was considered proportional to the number of patients classified as having adequate quality of life (indicator >26) in the general population. Data were collected while women waited for their routine appointment at the Health Unit. WHOQOL-Bref was used to evaluate the quality of life, and menopause rating scale (MRS) was used to determine climacteric symptoms. The level of physical activity was assessed by means of the International Physical Activity Questionnaire (IPAQ). To obtain the classification of PA levels, we used three categories: sedentary, moderately active, and very active. Statistical analysis was performed using the Minitab software, version 16. RESULTS: The mean age of the subjects was 49.8 years-old (±8.1) and they were predominantly Caucasian (72.7%), married (61.6%), non-smokers (93.5%), and had High School education (47.8%). Using the WHOQOL, mean scores were found to be significantly different between the groups (low, moderate, and vigorous physical activity), classified according to the domains of quality of life (p<0.01). Concerning physical activity and climacteric symptoms, significant differences were found for all domains: psychological (p<0.01), vegetative-somatic (p<0.01), and urogenital (p<0.01). CONCLUSIONS: Physical activity improves quality of life in middle-aged women.
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04-11-1998
Influência da tibolona e do exercício físico aeróbio sobre a antropometria e o perfil lipídico na menopausa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(6):362-362
Abstract
Influência da tibolona e do exercício físico aeróbio sobre a antropometria e o perfil lipídico na menopausa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(6):362-362
DOI 10.1590/S0100-72031998000600012
Views88Influência da Tibolona e do Exercício Físico Aeróbio sobre a Antropometria e o Perfil Lipídico na Menopausa[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Case Report06-26-2001
Endometrial osseous metaplasia and primary infertility
- Celeste P. Demeterco Reggiani,
- Marcelo K. Murata,
- Marcelo G. Cequinel,
- César A. Cornel,
- Jorjan Cruz, [ … ],
- Augusto F. Beduschi
Views83This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Case ReportEndometrial osseous metaplasia and primary infertility
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(2):119-121
DOI 10.1590/S0100-72032001000200010
- Celeste P. Demeterco Reggiani,
- Marcelo K. Murata,
- Marcelo G. Cequinel,
- César A. Cornel,
- Jorjan Cruz,
- Jean F. Francisco,
- Augusto F. Beduschi
Views83See moreEndometrial metaplastic ossification is a rare condition and can be partially explained by a neoformation in the endometrium, with calcium deposition. However, a common situation is the previous history of abortion with persistence of ossicles in the uterine cavity. The endometrial ossification was reported in a 31-year-old woman, without previous pregnancy or history of abortion. This patient presented dysmenorrhea and infertility. Pelvic ultrasonography showed a hyperechoic area in the uterine fundus. Histeroscopy was performed and an image suggestive of bone was seen. This tissue was removed by histeroscopy and the histopathological analysis confirmed endometrial ossification.
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Original Article07-27-2011
Presence of cells of the cervical transicional zone in cervicovaginal smears in women older than 40 years old
- Gisele Alborghetti Nai,
- Karen Karina Gusmão de Souza,
- Eliane Rissato Rodrigues,
- Ricardo Luís Barbosa
Views87This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePresence of cells of the cervical transicional zone in cervicovaginal smears in women older than 40 years old
Revista Brasileira de Ginecologia e Obstetrícia. 2011;33(3):128-132
DOI 10.1590/S0100-72032011000300005
- Gisele Alborghetti Nai,
- Karen Karina Gusmão de Souza,
- Eliane Rissato Rodrigues,
- Ricardo Luís Barbosa
Views87See morePURPOSE: to evaluate the frequency of cells of the cervical transitional zone (CTZ) in cervicovaginal smears of women older than 40 years. METHODS: we conducted a retrospective study with review of 24,316 Pap smear reports during the period from January 2005 to December 2008, to evaluate the cases without material of the CTZ. Exclusion criteria were: total hysterectomy, smears with severe atrophy or unsatisfactory for analysis, cases without visualization of the cervix or the external orifice of the cervix closed during examination and records without the patient’s age. A total of 21,866 cervical-vaginal cytology reports were included in this study. We evaluated the relationship between the presence of material of the CTZ and use of hormone replacement therapy (HRT) in patients aged 40 years or more and the relationship between presence of material of the CTZ and a moderate to intense inflammatory process in patients aged 39 years or less. Data were analyzed statistically by the χ2 test and Odds Ratio. RESULTS: only 11.2% of patients younger than 40 years had no material from the CTZ in their smears, while 47% patients older than 40 years had no material from the CTZ (p=0.0001). Most patients aged 40 years or more (92.1%) did not use HRT and this was not a predictor of incidence of CTZ material in these patients (p> 0.05). In contrast, most patients younger than 40 years without CTZ material (74.5%) had abundant inflammation in the smears (p=0.0001). CONCLUSION: patients aged 40 years or more had a lower incidence of material from the CTZ in cervicovaginal smears, and inflammation was a factor that contributed to the absence of CTZ material in the smears from patients younger than 40 years.
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Original Article07-13-2012
Surgical and non-surgical treatment of vaginal agenesis: analysis of a series of cases
- Juliana Straehl Marin,
- Lúcia Alves da Silva Lara,
- Adriana Valério da Silva,
- Rosana Maria dos Reis,
- Flávia Raquel Junqueira, [ … ],
- Ana Carolina Japur de Sá Rosa-e-Silva
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleSurgical and non-surgical treatment of vaginal agenesis: analysis of a series of cases
Revista Brasileira de Ginecologia e Obstetrícia. 2012;34(6):274-277
DOI 10.1590/S0100-72032012000600006
- Juliana Straehl Marin,
- Lúcia Alves da Silva Lara,
- Adriana Valério da Silva,
- Rosana Maria dos Reis,
- Flávia Raquel Junqueira,
- Ana Carolina Japur de Sá Rosa-e-Silva
Views90See morePURPOSE: This study aimed to evaluate the results of neovaginoplasty by a modified McIndoe-Bannister technique and by the non-surgical Frank technique. METHODS: This retrospective study was conducted on a convenience sample of 25 women with vaginal agenesis undergoing surgical or conservative treatment at an Infant-Pubertal Gynecology Outpatient Clinic. Data were obtained from the medical records. Fifteen women underwent the surgical McIndoe-Bannister modified technique Surgical Group, and 10 women underwent the non-surgical Frank technique Frank Group. The following parameters were considered for comparative analysis between the two samples: vaginometry, surgical and non-surgical complications, and sexual satisfaction after treatment. Sexual satisfaction was assessed by a simple question: How is your sex life? RESULTS: There were differences related to vaginal length before and after performing exercises in both Frank Group (initial vaginal length 2.4±2.0 cm versus 6.9±1.1 cm after treatment, p<0.0001) and Surgical Group (initial vaginal length 0.9±1.4 cm versus 8.0±0.8 cm after treatment, p<0.0001). Increased vaginal length was observed in Surgical Group compared to Frank Group (Frank Group=7.0±0.9 cm versus Surgical Group=8.0±0.8 cm, p=0.0005). Forty percent of Surgical Group women had surgical complications versus no complications with the Frank technique. All women reported to be satisfied with their sexual life. CONCLUSION: The present data indicate that both the surgical and Frank techniques are effective for the treatment of vaginal agenesis, resulting in the construction of a vagina that pewrmits sexual intercourse and sexual satisfaction. The favorable aspects of the Frank technique are related to its low cost and to the low rates of major complications.
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Editorial12-09-2013
Prematurity: when can it be prevented?
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(10):433-435
Views98This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
EditorialPrematurity: when can it be prevented?
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(10):433-435
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Original Article02-03-2013
Disability and factors associated with gestational low back pain
- Hellyne Giselle Reis Madeira,
- João Batista Santos Garcia,
- Marcus Vinícius Viégas Lima,
- Humberto Oliveira Serra
Views90This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleDisability and factors associated with gestational low back pain
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(12):541-548
DOI 10.1590/S0100-72032013001200003
- Hellyne Giselle Reis Madeira,
- João Batista Santos Garcia,
- Marcus Vinícius Viégas Lima,
- Humberto Oliveira Serra
Views90See morePURPOSE: To determine the prevalence of low back pain in pregnant women and to describe its characteristics and associated factors. METHODS: The participants were 269 pregnant women in the first to the third trimester of pregnancy, seen at the obstetrics outpatient clinic of a University Hospital in the Brazilian Northeast. We applied a questionnaire in order to obtain data regarding socio-demographic variables, obstetric history and characteristics of low back pain, as well as the Oswestry and Rolland Morris questionnaires to assess disability and a visual analog pain scale to measure pain intensity. RESULTS: The prevalence of low back pain was 73%, with the following characteristics: stabbing (62/31.6%), irradiation (162/82.6%), of daily frequency (105/53.5%), usually starting at night (83/42.3%) when it was also more intense (122/62.2%), and lasting about 1 hour in 118 women (60.2%). Pain improved with rest (100/51%), worsened when the women stood or sat for a long time (86/43.9%) and when they did housework (85/43.4%). The level of disability ranged from “mild” to “moderate” in most cases. Urinary tract infection (p=0.02) and the scores of the Oswestry and Rolland Morris questionnaires showed significant association with the visual analogue pain scale. CONCLUSION: The prevalence of back pain among pregnant women is high, with varying characteristics. The degree of disability is usually moderate and the presence of urinary infection and higher disability scores were associated with greater intensity of low back pain.
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FIGO Statement02-01-2019
International Federation of Gynecology and Obstetrics Global Declaration on Cervical Cancer Elimination
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(2):102-103
Views147This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
FIGO StatementInternational Federation of Gynecology and Obstetrics Global Declaration on Cervical Cancer Elimination
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(2):102-103
Views147We DeclareWe, the participants of the XXII FIGO World Congress of Obstetrics and Gynecology, held in Rio de Janeiro between 14th and 19th October 2018, hereby declare that we will work collaboratively to scale up interventions with the aim of eliminating cervical cancer as a public health concern.In line with cervical cancer elimination priority actions:[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article06-19-2019
Health-related Quality of Life in Women with Cervical Cancer
- Larissa Nascimento dos Santos,
- Luciana Castaneda
,
- Suzana Sales de Aguiar,
- Luiz Claudio Santos Thuler,
- Rosalina Jorge Koifman, [ … ],
- Anke Bergmann
Views249This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleHealth-related Quality of Life in Women with Cervical Cancer
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(4):242-248
- Larissa Nascimento dos Santos,
- Luciana Castaneda
,
- Suzana Sales de Aguiar,
- Luiz Claudio Santos Thuler,
- Rosalina Jorge Koifman,
- Anke Bergmann
Views249See moreAbstract
Objective
To analyze the factors associated with health-related quality of life (HRQoL) in women with cervical cancer (CC) in a single center in Rio de Janeiro, state of Rio de Janeiro, Brazil.
Methods
A cross-sectional study in women with a diagnosis of CC followed-up in the gynecology outpatient clinic of the Hospital do Câncer II (HCII, in the Portuguese acronym) of the Instituto Nacional de Câncer (INCA, in the Portuguese acronym). The data were collected from March to August 2015. Women with palliative care, communication/cognition difficulty, undergoing simultaneous treatment for other types of cancer, or undergoing chemotherapy and/or radiation therapy were excluded. For the evaluation of the HRQoL, a specific questionnaire for women with CC was used (Functional Assessment of Cancer Therapy – Cervix Cancer [FACT-Cx]). The total score of the questionnaire ranges from 0 to 168, with higher scores indicating a better HRQoL.
Results
A total of 115 women were included in the present study, with a mean age of 52.64 years old (standard deviation [SD] = 12.13). The domains of emotional (16.61; SD = 4.55) and functional well-being (17.63; SD = 6.15) were those which presented the worst scores. The factors that had an association with better HRQoL in women with CC were having a current occupation, a longer time since the treatment and diagnosis, and women who had undergone hysterectomy.
Conclusion
Considering the domains of HRQoL of the women treated for cervical cancer, a better score was observed in the domains of physical and social/family wellbeing. For most domains, better scores were found between those with a current occupation, with a longer time after the diagnosis and treatment, and among those who had undergone a hysterectomy.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article06-01-2018
Guidelines for HPV-DNA Testing for Cervical Cancer Screening in Brazil
- Luiz Carlos Zeferino,
- Joana Bragança Bastos,
- Diama Bhadra Andrade Peixoto do Vale,
- Rita Maria Zanine,
- Yara Lucia Mendes Furtado de Melo, [ … ],
- Fábio Russomano
Views370This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleGuidelines for HPV-DNA Testing for Cervical Cancer Screening in Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(6):360-368
- Luiz Carlos Zeferino,
- Joana Bragança Bastos,
- Diama Bhadra Andrade Peixoto do Vale,
- Rita Maria Zanine,
- Yara Lucia Mendes Furtado de Melo,
- Walquíria Quida Salles Pereira Primo,
- Flávia de Miranda Corrêa,
- Isabel Cristina Chulvis do Val,
- Fábio Russomano
Views370See moreAbstract
Evidence-based clinical guidelines ensure best practice protocols are available in health care. There is a widespread use of human papillomavirus deoxyribonucleic acid (HPVDNA) tests in Brazil, regardless of the lack of official guidelines. On behalf of the Brazilian Association for the Lower Genital Tract Pathology and Colposcopy (ABPTGIC, in the Portuguese acronym), a team of reviewers searched for published evidence and developed a set of recommendations for the use of HPV-DNA tests in cervical cancer screening in Brazil. The product of this process was debated and consensus was sought by the participants. One concern of the authors was the inclusion of these tests in the assessment of women with cytologic atypia and women treated for cervical intraepithelial neoplasia (CIN). Testing for HPV is recommended in an organized screening scenario to identify women with precursor lesions or asymptomatic cervical cancer older than 30 years of age, and it can be performed every 5 years. It also has value after the cytology showing atypical squamous cells of undetermined significance (ASC-US) or low-grade squamous intraepithelial lesions (LSILs) as a triage test for colposcopy, in the investigation of other cytological alterations when no abnormal findings are observed at colposcopy, seeking to exclude disease, or, further, after treatment of high-grade cervical intraepithelial neoplasia, to rule out residual disease.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article06-22-2020
Platelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio in Missed Abortion
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(5):235-239
Views251This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePlatelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio in Missed Abortion
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(5):235-239
Views251See moreAbstract
Objective
Missed abortion occurs in ~ 15% of all clinical pregnancies. The pathogenesis is not clearly known. However, defective placentation resulting in maternal systemic inflammatory response is considered responsible for missed abortion. Platelet lymphocyte ratio (PLR) and neutrophil lymphocyte ratio (NLR) are increasingly cited parameters of inflammation in the literature. However, no study evaluated the PLR and NLR rates in missed abortions so far. The aim of the present study is to investigate whether complete blood count (CBC) inflammatory parameters such as NLR and PLR are increased in patients with missed abortion.
Methods
Medical records of 40 pregnant women whose gestation ended in missed abortion at between 6 and14 weeks of gestation and of 40 healthy pregnant women were collected and compared retrospectively. The groups were compared regarding hemoglobin, hematocrit, platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), PLR and NLR.
Results
Platelet distribution width, NLR and PLR values were higher in the missed abortion group compared with the healthy pregnant women group (rates are p = 0.043; p = 0.038; and p = 0.010, respectively). Hematocrit, MPV, and lymphocyte values were found to be lower in the missed abortion group compared with the healthy pregnant women group (p = 0.027, p = 0.044 and p = 0.025, respectively).
Conclusion
The PDW, NLR and PLR values of the missed abortion group were reported high; and MPV values were reported low in the present study. These findings may help to speculate a defective placentation in the pathogenesis of missed abortion.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article11-01-2018
Comparative Study of the Use of HPA Lanolin and Breast Milk for Treating Pain Associated with Nipple Trauma
- Corintio Mariani Neto,
- Rosemeire Sartori de Albuquerque,
- Sonia Cristina de Souza,
- Renata Oliveira Giesta,
- Andrea Penha Spinola Fernandes, [ … ],
- Bárbara Mondin
Views271This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleComparative Study of the Use of HPA Lanolin and Breast Milk for Treating Pain Associated with Nipple Trauma
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(11):664-672
- Corintio Mariani Neto,
- Rosemeire Sartori de Albuquerque,
- Sonia Cristina de Souza,
- Renata Oliveira Giesta,
- Andrea Penha Spinola Fernandes,
- Bárbara Mondin
Views271Abstract
Objective
To compare two different treatments—the use of highly purified anhydrous (HPA) lanolin and expressed breast milk—for women with pain and nipple trauma during the breastfeeding process.
Method
A total of 180 puerperal women were randomly assigned to 2 groups: one was treated with HPA lanolin and the other with their own expressed breast milk. All of the participants received the same breastfeeding technique instructions and therapeutic care standard. Three assessments were performed: at the time of inclusion in the study (after randomization); after 48 hours; and after 7 days. At each interval, data was collected in relation to pain and trauma. A numerical/verbal category scale was used for the pain variable, and the nipple trauma score for the trauma variable. The results were subjected to statistical analysis using the chi-squared test, the Fisher exact test, the student t-test, and the Kolmogorov-Smirnov test. Generalized estimating equations were calculated using the STATA 12 statistical software package (StataCorp LLC, College Station, TX, USA) and IBM SPSS Statistics for Windows, Version 20.0 (IBM Corp, Armonk, NY, USA).
Results
There was pain improvement from the second to the third assessment in the group that used HPA lanolin, while the pain remained unchanged between these two periods (p< 0.001) in the breast milk group. In terms of trauma, improvement was identified in its extension and depth from the first to the third assessment, and it was higher in the HPA lanolin group than in the breast milk group (p= 0.025).
Conclusion
The treatment of pain and nipple trauma with HPA lanolin achieved better results than the one with breast milk, based on a 7-day treatment period.
Key-words breastfeeding/adverse effectsbreastfeeding/nipple painlanolin/therapeutic usenipples/injurieswound healing/drug effectsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article11-07-2019
Antiphospholipid Antibody Syndrome and Infertility
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(10):621-627
Views276This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleAntiphospholipid Antibody Syndrome and Infertility
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(10):621-627
Views276See moreAbstract
Antiphospholipid antibody syndrome (APS) is a systemic, autoimmune, prothrombotic disease characterized by persistent antiphospholipid antibodies (aPLs), thrombosis, recurrent abortion, complications during pregnancy, and occasionally thrombocytopenia. The objective of the present study was to review the pathophysiology of APS and its association with female infertility. A bibliographic review of articles of the past 20 yearswas performed at the PubMed, Scielo, and Bireme databases. Antiphospholipid antibody syndrome may be associated with primary infertility, interfering with endometrial decidualization and with decreased ovarian reserve. Antiphospholipid antibodies also have direct negative effects on placentation, when they bind to the trophoblast, reducing their capacity for invasion, and proinflammatory effects, such as complement activation and neutrophil recruitment, contributing to placental insufficiency, restricted intrauterine growth, and fetal loss. In relation to thrombosis, APS results in a diffuse thrombotic diathesis, with global and diffuse dysregulation of the homeostatic balance. Knowing the pathophysiology of APS, which is closely linked to female infertility, is essential for new therapeutic approaches, specialized in immunomodulation andinflammatory signaling pathways, to provide important advances in its treatment.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article03-27-2020
Gestational Diabetes in the Population Served by Brazilian Public Health Care. Prevalence and Risk Factors
- Pâmela Antoniazzi dos Santos
,
- José Mauro Madi
,
- Emerson Rodrigues da Silva
,
- Daiane de Oliveira Pereira Vergani
,
- Breno Fauth de Araújo
,
[ … ], - Rosa Maria Rahmi Garcia
Views341This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleGestational Diabetes in the Population Served by Brazilian Public Health Care. Prevalence and Risk Factors
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):12-18
- Pâmela Antoniazzi dos Santos
,
- José Mauro Madi
,
- Emerson Rodrigues da Silva
,
- Daiane de Oliveira Pereira Vergani
,
- Breno Fauth de Araújo
,
- Rosa Maria Rahmi Garcia
Views341See moreAbstract
Objective
To assess the prevalence of gestational diabetes mellitus and the main associated risk factors in the population served by the Brazilian Unified Health System in the city of Caxias do Sul, state of Rio Grande do Sul.
Materials and Methods
A descriptive, cross-sectional and retrospective study was conducted. Maternal variables were collected from the medical records of all pregnant women treated at the basic health units in 2016. Hyperglycemia during pregnancy (pregestational diabetes, overt diabetes and gestational diabetes mellitus) was identified by analyzing the results of a 75-g oral glucose tolerance test, as recommended by the Brazilian Ministry of Health. Based on the data, the women were allocated into two groups: the gestational diabetes group and the no gestational diabetes group.
Results
The estimated prevalence of gestational diabetes among 2,313 pregnant women was of 5.4% (95% confidence interval [95%CI]: 4.56-6.45). Pregnant women with 3 or more pregnancies had twice the odds of having gestational diabetes compared with primiparous women (odds ratio [OR]=2.19; 95%CI: 1.42-3.37; p<0.001). Pregnant women aged 35 years or older had three times the odds of having gestational diabetes when compared with younger women (OR=3.01; 95%CI: 1.97-4.61; p<0.001). Overweight pregnant women were 84% more likely to develop gestational diabetes than those with a body mass index lower than 25 kg/m2 (OR =1.84; 95%CI: 1.25-2.71; p=0.002). A multivariable regression analysis showed that being overweight and being 35 years old or older were independent variables.
Conclusion
In this population, the prevalence of gestational diabetes mellitus was of 5.4%. Age and being overweight were predictive factors for gestational diabetes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Pâmela Antoniazzi dos Santos
-
Original Article09-01-2018
Urinary Incontinence and Quality of Life in Female Patients with Obesity
- Christiana Campani Nygaard,
- Lucas Schreiner,
- Thiago Picolli Morsch,
- Rodrigo Petersen Saadi,
- Marina Faria Figueiredo, [ … ],
- Alexandre Vontobel Padoin
Views193This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleUrinary Incontinence and Quality of Life in Female Patients with Obesity
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(9):534-539
- Christiana Campani Nygaard,
- Lucas Schreiner,
- Thiago Picolli Morsch,
- Rodrigo Petersen Saadi,
- Marina Faria Figueiredo,
- Alexandre Vontobel Padoin
Views193See moreAbstract
Objective
To analyze the prevalence of urinary incontinence (UI) in female patients with an indication for bariatric surgery, to investigate the potential risk factors and the impact on quality of life.
Methods
A cross-sectional study with female patients with obesity. The evaluation consisted of a structured interview, a specific study form and quality of life questionnaires. The Poisson regression was performed to identify independent risk factors related to UI.
Results
A total of 221 patients were enrolled; 118 of the study participants (53.4%) reported UI episodes. Mixed UI (MUI), stress UI (SUI) only, and urgency UI (UUI) only were reported by 52.5% (62), 33.9% (40) , and 13.5% (16) of these patients respectively. The prevalence of UI was increased by 47% among the women who had given birth vaginally and by 34% of the women who had entered menopause. Vaginal delivery and menopause were identified as independent risk factors related to UI. The mean International Consultation on Incontinence Questionnaire – Short Form (ICIQ-SF) score was 9.36 ± 4.9. The severity of symptoms was considered moderate in 53.3% (63) of the patients with UI.
Conclusion
Urinary incontinence impacts quality of life negatively, and the prevalence of UI is high among obese patients. In the present study, vaginal delivery and menopause were independently associated with UI.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article03-04-2022
Screening of Perinatal Depression Using the Edinburgh Postpartum Depression Scale
- Tenilson Amaral Oliveira
,
- Guilherme Guarany Cardoso Magalhães Luzetti
,
- Márcia Maria Auxiliadora Rosalém
,
- Corintio Mariani Neto
Views490This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleScreening of Perinatal Depression Using the Edinburgh Postpartum Depression Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(5):452-457
- Tenilson Amaral Oliveira
,
- Guilherme Guarany Cardoso Magalhães Luzetti
,
- Márcia Maria Auxiliadora Rosalém
,
- Corintio Mariani Neto
Views490See moreAbstract
Objective
To detect depression during pregnancy and in the immediate postpartum period using the Edinburgh postpartum depression scale (EPDS).
Methods
Cross sectional study of 315 women, aged between 14 and 44 years, who received perinatal care at the Leonor Mendes de Barros Hospital, in São Paulo, between July 1st, 2019 and October 30th, 2020. The cutoff point suggesting depression was ≥ 12.
Results
The screening indicated 62 (19.7%) patients experiencing depression. Low family income, multiparity, fewer prenatal appointments, antecedents of emotional disorders, dissatisfaction with the pregnancy, poor relationship with the partner, and psychological aggression were all risk factors associated with depression in pregnancy or in the immediate postpartum period. Antecedents of depression and psychology aggression during pregnancy were significant variables for predicting perinatal depression in the multivariate analysis.
Conclusion
There is a significant association between the occurrence of perinatal depression and the aforementioned psychosocial factors. Screening patients with the EPDS during perinatal and postpartum care could facilitate establishing a line of care to improve the wellbeing of mother and infant.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Tenilson Amaral Oliveira
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