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Editorial
Ética em pesquisa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(9):494-494
04-09-1998
Views45This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
EditorialÉtica em pesquisa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(9):494-494
04-09-1998This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Estudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):424-424
04-09-1998
Views40This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesEstudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):424-424
04-09-1998DOI 10.1590/S0100-72031998000700011
Views40Estudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Estudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-423
04-09-1998
Views35This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesEstudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-423
04-09-1998DOI 10.1590/S0100-72031998000700009
Views35Estudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Sangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada – Recife (PE)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-424
04-09-1998
Views39This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesSangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada – Recife (PE)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-424
04-09-1998DOI 10.1590/S0100-72031998000700010
Views39Sangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada Recife (PE) […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Relato de Caso
Complete Mole in Twin Pregnancy: a Case Report
- Izildinha Maestá,
- Iracema M.P. Calderon,
- Marilza V.C. Rudge,
- Magaly M. Sales,
- Fabiano P. Saggioro, [ … ],
- José Carlos Peraçoli
04-09-1998
Views72This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Relato de CasoComplete Mole in Twin Pregnancy: a Case Report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):415-419
04-09-1998DOI 10.1590/S0100-72031998000700008
- Izildinha Maestá,
- Iracema M.P. Calderon,
- Marilza V.C. Rudge,
- Magaly M. Sales,
- Fabiano P. Saggioro,
- José Carlos Peraçoli
Views72Twin pregnancy in which a normal fetus and a complete mole develop at the same time is a rare event. Clinical complications and malignancy are frequent in this type of disease.This report is about a case of a late diagnosis due to the presence of the fetus. The diagnosis was made when the pregnancy was interrupted and then confirmed by histopathological study and flow cytometry. The pregnancy was terminated transpelvically due to massive uterine hemorrhage. The post-molar follow-up showed the persistence of high levels of bhCG. The patient’s complete recovery was achieved after the administration of methotrexate. The diagnosis, natural history, and procedures for this rare disease are discussed in view of this case.
Key-words ChemotherapyComplete hydatidiform moleGestational trophoblastic diseaseHemorrhagePregnancy complicationsTwin pregnancyUltrasonographySee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Relato de Caso
Clear Cell Adenocarcinoma of the Endocervix in a 7-year-old Child
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):411-414
04-09-1998
Views86This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Relato de CasoClear Cell Adenocarcinoma of the Endocervix in a 7-year-old Child
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):411-414
04-09-1998DOI 10.1590/S0100-72031998000700007
Views86See moreClear cell adenocarcinoma of the vagina and cervix is a rare disease associated commonly with the use of diethylstilbestrol (DES) during pregnancy. The most commom complaint is irregular vaginal bleeding, which could be confused with vaginitis in children and abnormalities in the hypothalamic-pituitary axis in adolescents. We report a case of clear cell adenocarcinoma of the endocervix in a 7-year-old child who was attended at the Children and Adolescent Gynecology Sector, and we call attention to the diagnosis of genital cancer which, in spite of its rarity at this age, must be considered in children with genital bleeding.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Equipamentos e Métodos
Endometrial Resection by Video-Hysteroscopy: experience in a Teaching Hospital
- Caio Parente Barbosa,
- Marcelo Ettruri Santos,
- Ana Cristina Napolitano,
- Paula Harue Tamanaka,
- Emerson Barchi Cordts
04-09-1998
Views78This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Equipamentos e MétodosEndometrial Resection by Video-Hysteroscopy: experience in a Teaching Hospital
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):405-410
04-09-1998DOI 10.1590/S0100-72031998000700006
- Caio Parente Barbosa,
- Marcelo Ettruri Santos,
- Ana Cristina Napolitano,
- Paula Harue Tamanaka,
- Emerson Barchi Cordts
Views78See moreObjective: to demonstrate the effectiveness of video-hysteroscopic endometrial resection in the treatment of abnormal uterine bleeding. Patients and method: The authors studied 60 records of patients with abnormal uterine bleeding who did not respond to clinical treatment. Results: eighty-eight percent of the patients had adequate response to the treatment (53% oligomenorrhea and 35% amenorrhea). The complication rate was 8.3% (5 uterine perforations). Conclusion: video-hysteroscopic endometrial resection is an effective technique to treat abnormal uterine bleeding which failed to respond to clinical management. The intra and postoperative complication rates are low.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Maternal Mortality in São Paulo City in 1996
- Luis Carlos Pazero,
- Paulo Afonso Ferrigno Marcus,
- Carlos Eduardo Pereira Vega,
- Krikor Boyaciyan,
- Sônia Antonini Barbosa
04-09-1998
Views104PlumX Metrics- Citations
- Citation Indexes: 4
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- Full Text Views: 8584
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisMaternal Mortality in São Paulo City in 1996
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):395-403
04-09-1998DOI 10.1590/S0100-72031998000700005
- Luis Carlos Pazero,
- Paulo Afonso Ferrigno Marcus,
- Carlos Eduardo Pereira Vega,
- Krikor Boyaciyan,
- Sônia Antonini Barbosa
Views104Purpose: to establish a list of diseases promoting maternal death according to frequency. Methods: In 1996, 65,406 deaths were recorded in the City of São Paulo, 26,778 of which were of women. Of these, 4591 were within the 10-49 year age bracket. We analyzed the latter group, regarding at the field “Cause of Death” in the Death Certificate, trying to establish some correlation between the described pathology, and the pregnancy-puerperium cycle. We separated for a further study 293 Death Certificates, from which we selected, after hospital survey and/or home visits, a total of 119 positive cases for maternal death. The positive cases for maternal death were then tabulated, grouped and analyzed according to age and pathology, using the great medical care groups. Results: as regards the 119 positive cases for maternal death, we did not find any reference to the pregnancy-puerperium state in 53 of them (that is, 40.54% subnotifying). The cases were grouped according to pathology, where we found a predominance of eclampsia/pre-eclampsia cases (18.02%), followed by cases resulting from hemorrhagic complications in the third quarter and puerperium (12.61%), abortion complications (12.61%), puerperal infection (9.91%) and cardiopathies (9.91%). Conclusions: for the first time, we are publishing the Late Maternal Mortality Coefficient for the City of São Paulo, which was 51.33/100,000 born alive. However, we used for the official publication the Maternal Mortality Coefficient for death within up to 42 days of puerperium, which was, 48.03/100,000 born alive for the city of São Paulo. We should bear in mind that no correction factor should be applied to these figures since we have made an active search of cases.
Key-words Cardiopathy in pregnancyEclampsiaHemorrhagic complications in pregnancyMaternal mortalityMaternal mortality coefficientPregnancy complicationsSee morePlumX Metrics- Citations
- Citation Indexes: 4
- Usage
- Full Text Views: 8584
- Abstract Views: 845
- Captures
- Readers: 9
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article
Sacral neuromodulation therapy for urinary and defecatory disorders: experience in a Latin American public hospital
- Marcelo Mass-Lindenbaum
,
- Diego Arévalo-Vega
,
- Isidora Aleuanlli
,
- Fernanda Santis-Moya
,
- Andrea Maluenda
,
[ … ], - Javier Pizarro-Berdichevsky
00-00-2024
Summary
Original ArticleSacral neuromodulation therapy for urinary and defecatory disorders: experience in a Latin American public hospital
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo11
00-00-2024- Marcelo Mass-Lindenbaum
,
- Diego Arévalo-Vega
,
- Isidora Aleuanlli
,
- Fernanda Santis-Moya
,
- Andrea Maluenda
,
- Eitan Dines
,
- Miriam Cohen-Vaizer
,
- Álvaro Saavedra
,
- Trinidad Raby
,
- Bernardita Blumel
,
- Rodrigo Cuevas
,
- Simone Pohlhammer
,
- Gabriela Alarcon
,
- Marco Arellano Albornoz
,
- Javier Pizarro-Berdichevsky
Views558Abstract
Objective:
To show the experience of a Latin American public hospital, with SNM in the management of either OAB, NOUR or FI, reporting feasibility, short to medium-term success rates, and complications.
Methods:
A retrospective cohort was conducted using data collected prospectively from patients with urogynecological conditions and referred from colorectal surgery and urology services between 2015 and 2022.
Results:
Advanced or basic trial phases were performed on 35 patients, 33 (94%) of which were successful and opted to move on Implantable Pulse Generator (GG) implantation. The average follow-up time after definitive implantation was 82 months (SD 59). Of the 33 patients undergoing, 27 (81%)reported an improvement of 50% or more in their symptoms at last follow-up. Moreover, 30 patients (90%) with a definitive implant reported subjective improvement, with an average PGI-I “much better” and 9 of them reporting to be “excellent” on PGI-I.
Conclusion:
SNM is a feasible and effective treatment for pelvic floor dysfunction. Its implementation requires highly trained groups and innovative leadership. At a nation-wide level, greater diffusion of this therapy among professionals is needed to achieve timely referral of patients who require it.
Key-words Electric stimulation therapyfecal incontinenceIncontinenceNon-obstructive urinary retentionoveractiveSacral neuromodulationUrinary bladderSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Marcelo Mass-Lindenbaum
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Original Article
Real-world utilization pattern of dydrogesterone in 7287 Indian women with obstetric and gynecological conditions: data from multicentric, retrospective study
- Jaydeep Tank
,
- Sanjay Gupte
,
- Purna Chandra Mahapatra
,
- Jayanthi Reddy
,
- Pratima Mittal
,
[ … ], - Onkar Swami
00-00-2024
Views548This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleReal-world utilization pattern of dydrogesterone in 7287 Indian women with obstetric and gynecological conditions: data from multicentric, retrospective study
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo18
00-00-2024- Jaydeep Tank
,
- Sanjay Gupte
,
- Purna Chandra Mahapatra
,
- Jayanthi Reddy
,
- Pratima Mittal
,
- Ashish Kumar Mukhopadhyay
,
- Lila Vyas
,
- Achla Batra
,
- Mahesh Gupta
,
- Sunita Tandulwadkar
,
- Sunita Chandra
,
- Vidya Bhat
,
- Kawita Bapat
,
- Parikshit Tank
,
- Ketan Kulkarni
,
- Onkar Swami
Views548Abstract
Objective:
Despite the literature on dydrogesterone, studies on dydrogesterone utilization patterns are largely lacking in Indian patients.
Methods:
This was a multi-center, retrospective, observational, cross-sectional, and descriptive study across 817 centers in India. Data of patients who received dydrogesterone in past and provided consent for future use of their medical record for research purpose was were retrieved and analyzed.
Results:
Data of 7287 subjects (aged 29.55±4.84 years) was analyzed. Threatened abortion was the most common indication for which the subjects received dydrogesterone (46.9%) followed by recurrent pregnancy loss. Polycystic ovary syndrome (PCOS), thyroid disorders and anemia were the most common comorbid conditions and prior pregnancy loss, advanced maternal age and obesity were the most common risk factors seen in subjects who received dydrogesterone. Total 27.5% of subjects received a loading dose of dydrogesterone, and majority (64%) received 40 mg as loading dose. 10 mg dose was used as maintenance or regular dose in 81.4% of the subjects. Twice daily (BID) was the most common dosing frequency (66.6%). The most common concomitant medications being taken by the subjects on dydrogesterone included folic acid (45.1%), iron supplements (30.3%) and calcium and vitamin D3 supplements (25.5%). Another progesterone preparation (oral, injection, vaginal, tubal) other than dydrogesterone was used concurrently in 7.8% of subjects.
Conclusion:
The study helped to identify the patient population that is benefitted by dydrogesterone and the preferred indications, risk factors, comorbid conditions and concomitant medication used in this patient population at real-life scenario.
Key-words Comorbid conditionsConcomitant medicationsdydrogesteroneGynecological conditionsIndian womenRisk factorsThreatened abortionUtilization patternSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Jaydeep Tank
-
Original Article
Assessment of sexual and body esteem in postpartum women with or without perineal laceration: a cross-sectional study with cultural translation and validation of the Vaginal Changes Sexual and Body Esteem Scale
- Renata Stefânia Olah de Souza
,
- Adriana Gomes Luz
,
- Ruth Zielinski
,
- Luis Otavio Zanatta Sarian
,
- Cassia Raquel Teatin Juliato
,
[ … ], - Luiz Gustavo Oliveira Brito
04-09-2024
Summary
Original ArticleAssessment of sexual and body esteem in postpartum women with or without perineal laceration: a cross-sectional study with cultural translation and validation of the Vaginal Changes Sexual and Body Esteem Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo35
04-09-2024- Renata Stefânia Olah de Souza
,
- Adriana Gomes Luz
,
- Ruth Zielinski
,
- Luis Otavio Zanatta Sarian
,
- Cassia Raquel Teatin Juliato
,
- Lucia Alves da Silva Lara
,
- Luiz Gustavo Oliveira Brito
Views537See moreObjective:
We aimed to translate and determine cultural validity of the Vaginal Changes Sexual and Body Esteem Scale (VSBE) for Brazilian Portuguese language in postpartum women who underwent vaginal delivery with or without perineal laceration and cesarean section.
Methods:
A cross-sectional study conducted virtually, with online data collection through a survey with 234 postpartum women of 975 that were invited. Clinical, sociodemographic, and psychometric variables from the VSBE questionnaire were analyzed (content validity index, internal consistency, test-retest reliability, construct/structural and discriminant validity). Multivariate analysis was performed to explore associated factors with the presence of perineal laceration.
Results:
One-hundred fifty-eight women experienced vaginal delivery, of which 24.79% had an intact perineum, 33.33% had perineal laceration, and 9.4% underwent episiotomy; and 76 participants had cesarean sections. Women with perineal laceration were older, presented dyspareunia and previous surgeries than women without perineal laceration (p<0.05). For VSBE, a high internal consistency (Cronbach's α > 0.7) was observed, but it did not correlate with Body Attractiveness Questionnaire and Female Sexual Function Index; however, it correlated with the presence of women sutured for perineal laceration. Moreover, VSBE presented good structural validity with two loading factors after exploratory factor analysis. VSBE also demonstrated discriminant validity between the presence or absence of perineal laceration. The presence of urinary incontinence (UI) (OR=2.716[1.015-4.667];p=0.046) and a higher VSBE total score (OR=1.056[1.037-1.075];p<0.001) were the only factors associated with perineal laceration.
Conclusion:
Vaginal Changes Sexual and Body Esteem Scale demonstrated appropriate translation and good internal consistency, discriminant/construct validity and reliability. Vaginal Changes Sexual and Body Esteem Scale total score and presence of UI were associated with women that underwent perineal laceration.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Renata Stefânia Olah de Souza
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Case Report
Identification of a rare copy number polymorphic gain at 3q12.2 with candidate genes for familial endometriosis
- Flávia Gaona Oliveira
,
- Júlio Cesar Rosa-e-Silva
,
- Alexandra Galvão Gomes
,
- Juliana Dourado Grzesiuk
,
- Thiago Vidotto
,
[ … ], - Lúcia Martelli
00-00-2024
Summary
Case ReportIdentification of a rare copy number polymorphic gain at 3q12.2 with candidate genes for familial endometriosis
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo12
00-00-2024- Flávia Gaona Oliveira
,
- Júlio Cesar Rosa-e-Silva
,
- Alexandra Galvão Gomes
,
- Juliana Dourado Grzesiuk
,
- Thiago Vidotto
,
- Jeremy Andrew Squire
,
- Rodrigo Alexandre Panepucci
,
- Juliana Meola
,
- Lúcia Martelli
Views536Abstract
Endometriosis is a complex disease that affects 10-15% of women of reproductive age. Familial studies show that relatives of affected patients have a higher risk of developing the disease, implicating a genetic role for this disorder. Little is known about the impact of germline genomic copy number variant (CNV) polymorphisms on the heredity of the disease. In this study, we describe a rare CNV identified in two sisters with familial endometriosis, which contain genes that may increase the susceptibility and progression of this disease. We investigated the presence of CNVs from the endometrium and blood of the sisters with endometriosis and normal endometrium of five women as controls without the disease using array-CGH through the Agilent 2x400K platform. We excluded common CNVs that were present in the database of genomic variation. We identified, in both sisters, a rare CNV gain affecting 113kb at band 3q12.2 involving two candidate genes: ADGRG7 and TFG. The CNV gain was validated by qPCR. ADGRG7 is located at 3q12.2 and encodes a G protein-coupled receptor influencing the NF-kappaβ pathway. TFG participates in chromosomal translocations associated with hematologic tumor and soft tissue sarcomas, and is also involved in the NF-kappa B pathway. The CNV gain in this family provides a new candidate genetic marker for future familial endometriosis studies. Additional longitudinal studies of affected families must confirm any associations between this rare CNV gain and genes involved in the NF-kappaβ pathway in predisposition to endometriosis.
Key-words Array-CGHDNA copy number variationsEndometriosisEndometriumgeneticGenomic structural variationHeredityPolymorphismSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Flávia Gaona Oliveira
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Original Article
Fertility preservation in female cancer patients in Brazil: perceptions and attitudes of infertility specialists
- Renata Lack Ranniger
,
- Rívia Mara Lamaita
,
- Bárbara Flecha D’Abreu
,
- Mariana Rodrigues Tolentino
,
- Eduardo Batista Cândido
,
[ … ], - Agnaldo Lopes Silva-Filho
04-09-2024
Views523This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleFertility preservation in female cancer patients in Brazil: perceptions and attitudes of infertility specialists
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo25
04-09-2024- Renata Lack Ranniger
,
- Rívia Mara Lamaita
,
- Bárbara Flecha D’Abreu
,
- Mariana Rodrigues Tolentino
,
- Eduardo Batista Cândido
,
- Warne Pedro Andrade
,
- Angélica Nogueira-Rodrigues
,
- Agnaldo Lopes Silva-Filho
Views523Objective:
Fertility preservation is a priority in oncology for female cancer patients. However, there is a lack of communication between infertility specialists and oncologists. This study aimed to evaluate infertility specialists’ perceptions and experiences regarding fertility preservation.
Methods:
Conduct an online survey to profile infertility specialists. Participants were infertility affiliated with the Brazilian Federation of Gynecology and Obstetrics Associations (FEBRASGO). The specialists received an online survey, which response rate were 30.9%, most of whom were in southern and southeastern. The survey consisted on 14 questions about the infertility specialists’ location, techniques in clinical practice, treatment successful rate, patients idea, etc.
Results:
The average experience in human reproduction were 15.5 ± 10.2 years (mean ± standard deviation, range 1-40). Among reproductive-aged female cancer patients recommended for fertility preservation, 60.3 ± 28.8% (range 10-100%) underwent preservation procedures. Main barriers were cost (41%), oncologists’ knowledge or acceptance (35%) and accessibility (9%). Most infertility specialists (58%) considered 40 years the limit for fertility preservation. Leukemia, lymphoma, breast and ovarian cancers were prioritized for fertility preservation, while lung, thyroid, gastric, and brain cancers were less relevant.
Conclusion:
This is the first Brazilian study about infertility specialists’ perceptions on oncology patients access to fertility preservation. These patients primarily receive treatment in the public health system, while infertility specialists mainly work in the private healthcare. This healthcare mode is currently fragmented, but integrating these experts is enhancing patient access to fertility preservation. Studies on this topic are still warranted.
Key-words attitudesFertilityFertility preservationgynecologistshealth knowledgeNeoplasmsOncologistsOocyte retrievalpracticeReproductionsurveys and questionnairesSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Renata Lack Ranniger
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Review Article
A meta-analysis of ferric carboxymaltose versus other intravenous iron preparations for the management of iron deficiency anemia during pregnancy
- Sanjay Gupte
,
- Ashis Mukhopadhyay
,
- Manju Puri
,
- P. M. Gopinath
,
- Reena Wani
,
[ … ], - Onkar C. Swami
03-15-2024
Views505This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleA meta-analysis of ferric carboxymaltose versus other intravenous iron preparations for the management of iron deficiency anemia during pregnancy
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo21
03-15-2024- Sanjay Gupte
,
- Ashis Mukhopadhyay
,
- Manju Puri
,
- P. M. Gopinath
,
- Reena Wani
,
- J. B. Sharma
,
- Onkar C. Swami
Views505Abstract
Objective:
We conducted a meta-analysis of randomized clinical trials evaluating the clinical effects of ferric carboxymaltose therapy compared to other intravenous iron in improving hemoglobin and serum ferritin in pregnant women. We also assessed the safety of ferric carboxymaltose vs. other intravenous iron.
Data source:
EMBASE, PubMed, and Web of Science were searched for trials related to ferric carboxymaltose in pregnant women, published between 2005 and 2021. We also reviewed articles from google scholar. The keywords “ferric carboxymaltose,” “FCM,” “intravenous,” “randomized,” “pregnancy,” “quality of life,” and “neonatal outcomes” were used to search the literature. The search was limited to pregnant women.
Selection of studies:
Studies related to ferric carboxymaltose in pregnancy were scanned. Observational studies, review articles, and case reports were excluded. Randomized studies in pregnant women involving ferric carboxymaltose and other intravenous iron formulations were shortlisted. Of 256 studies, nine randomized control trials were selected.
Data collection:
Two reviewers independently extracted data from nine selected trials
Data synthesis:
The final effect size for increase in hemoglobin after treatment was significant for ferric carboxymaltose vs. iron sucrose/iron polymaltose (standard mean difference 0.89g/dl [95% confidence interval 0.27,1.51]). The final effect size for the increase in ferritin after treatment was more for ferric carboxymaltose vs. iron sucrose/iron polymaltose (standard mean difference 22.53µg/L [-7.26, 52.33]). No serious adverse events were reported with ferric carboxymaltose or other intravenous iron.
Conclusion:
Ferric carboxymaltose demonstrated better efficacy than other intravenous iron in increasing hemoglobin and ferritin levels in treating iron deficiency anemia in pregnant women.
Key-words AnemiaFerric carboximaltoseFerric oxideferritinhemoglobinIntravenous ironIron polymaltoseIron sucroseIron-deficiency anemiaPregnancysaccharatedSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Sanjay Gupte
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Review Article
Non-RhD alloimmunization in pregnancy: an updated review
- Sabrina Menes Ares
,
- Luciano Marcondes Machado Nardozza
,
- Edward Araujo Júnior
,
- Eduardo Félix Martins Santana
00-00-2024
Views498This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleNon-RhD alloimmunization in pregnancy: an updated review
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo22
00-00-2024- Sabrina Menes Ares
,
- Luciano Marcondes Machado Nardozza
,
- Edward Araujo Júnior
,
- Eduardo Félix Martins Santana
Views498Abstract
RhD alloimmunization in pregnancy is still the main cause of hemolytic disease of the fetus and neonate (HDFN). Nevertheless, there are other antigens that may be associated with the occurrence of this phenomenon and that have been growing in proportion, given that current prevention strategies focus only on anti-RhD antibodies. Although not widespread, the screening and diagnostic management of the disease caused by these antibodies has recommendations in the literature. For this reason, the following review was carried out with the objective of listing the main red blood cell antigen groups described — such as Rh, ABO, Kell, MNS, Duffy, Kidd, among others — addressing the clinical importance of each one, prevalence in different countries, and recommended management when detecting such antibodies during pregnancy.
Key-words Blood group antigensErythroblastosisfetalFetal diseasesNon-Rh alloimmunizationPregnancyPrevalenceRh isoimmunizationSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Sabrina Menes Ares
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Original Article
Validation of the Brazilian 10-item Cervantes Scale for the assessment of menopausal symptoms
- Mona Lúcia Dall’Agno
,
- Charles Francisco Ferreira
,
- Fernanda Vargas Ferreira
,
- Pedro do Valle Teichmann
,
- Jéssica Zandoná
,
[ … ], - Maria Celeste Osório Wender
00-00-2024
Summary
Original ArticleValidation of the Brazilian 10-item Cervantes Scale for the assessment of menopausal symptoms
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo7
00-00-2024- Mona Lúcia Dall’Agno
,
- Charles Francisco Ferreira
,
- Fernanda Vargas Ferreira
,
- Pedro do Valle Teichmann
,
- Jéssica Zandoná
,
- Faustino Ramón Pérez-López
,
- Maria Celeste Osório Wender
Views496See moreAbstract
Objective:
To validate the 10-item Cervantes Scale (CS-10) among Brazilian women.
Methods:
This is a cross-sectional observational study involving women in the community aged 40–55 years in the Southern region of Brazil. They completed a general health, habits and socio-demographic questionnaire, the CS-10 and the Women’s Health Questionnaire (WHQ). Women unable to understand the survey, not consenting to participate, or having incapacity imposing difficulties during the completion of the questionnaire were excluded. A Confirmatory Factor Analysis (CFA) was conducted with the AMOS 16.0 software. Chi-square of degrees of freedom (χ2/df), the Comparative Fit Index (CFI), the Tucker-Lewis Index (TLI) and the Root-Mean-Square Error of Approximation (RMSEA) were used as indices of goodness of fit. Cronbach’s alpha coefficient was used for internal consistency.
Results:
A total of 422 women were included (premenopausal n=35, perimenopausal n=172, postmenopausal n=215). The CFA for the CS-10 showed a good fit (χ²/df=1.454, CFI=0.989; TLI=0.985; RMSEA=0.033; CI 90%=0.002-0.052; PCLOSE=0.921; Model p=0.049). Good reliability was established in CS-10 and WHQ (Cronbach’s alpha=0.724). Postmenopausal women had higher total CS-10 scores (p≤0.0001), reflecting worse quality of life (QoL) related to menopause symptoms and confirming the greater symptomatology evaluated by high total scores for WHQ found in this population when compared to those in the premenopausal period (p=0.041).
Conclusion:
The CS-10 is a consistent tool for health-related QoL in Brazilian mid-aged women.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Mona Lúcia Dall’Agno
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Original Article
Habits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
- Marcela Grigol Bardin
,
- Paulo César Giraldo
,
- Cristina Laguna Benetti-Pinto
,
- José Marcos Sanches
,
- Camila Carvalho de Araujo
,
[ … ], - Rose Luce Gomes do Amaral
04-08-2022
Views281This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleHabits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):169-177
04-08-2022- Marcela Grigol Bardin
,
- Paulo César Giraldo
,
- Cristina Laguna Benetti-Pinto
,
- José Marcos Sanches
,
- Camila Carvalho de Araujo
,
- Rose Luce Gomes do Amaral
Views281See moreAbstract
Objective
To evaluate genital hygiene among women with and without bacterial vaginosis (BV) and/or vulvovaginal candidiasis (VVC).
Methods
A cross-sectional study of reproductive-aged women who underwent gynecological and laboratory tests and fulfilled a genital hygiene questionnaire.
Results
This study evaluated 166 healthy controls and 141 women diagnosed with either BV (n=72), VVC (n=61), or both (n=8). The use of intimate soap and moist wipes after urination was more frequent among healthy women (p=0.042 and 0.032, respectively). Compared to controls, bactericidal soap was more used by women with BV (p=0.05).
Conclusion
Some hygiene habits were associated to BV and/or VVC. Clinical trials should address this important issue in women’s health.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Marcela Grigol Bardin
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Original Article
Temporal Evolution of Maternal Mortality: 1980-2019
- Janete Vettorazzi
,
- Edimárlei Gonsales Valério
,
- Maria Alexandrina Zanatta
,
- Mariana Hollmann Scheffler
,
- Sergio Hofmeister de Almeida Martins Costa
,
[ … ], - José Geraldo Lopes Ramos
11-29-2021
Views184This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleTemporal Evolution of Maternal Mortality: 1980-2019
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(9):662-668
11-29-2021- Janete Vettorazzi
,
- Edimárlei Gonsales Valério
,
- Maria Alexandrina Zanatta
,
- Mariana Hollmann Scheffler
,
- Sergio Hofmeister de Almeida Martins Costa
,
- José Geraldo Lopes Ramos
Views184Abstract
Objective
To determine the profile of maternal deaths occurred in the period between 2000 and 2019 in the Hospital de Clínicas de Porto Alegre (HCPA, in the Portuguese acronym) and to compare it with maternal deaths between 1980 and 1999 in the same institution.
Methods
Retrospective study that analyzed 2,481 medical records of women between 10 and 49 years old who died between 2000 and 2018. The present study was approved by the Ethics Committee (CAAE 78021417600005327).
Results
After reviewing 2,481 medical records of women who died in reproductive age, 43 deaths had occurred during pregnancy or in the postpartum period. Of these, 28 were considered maternal deaths. The maternal mortality ratio was 37.6 per 100,000 live births. Regarding causes, 16 deaths (57.1%) were directly associated with pregnancy, 10 (35.1%) were indirectly associated, and 2 (7.1%) were unrelated. The main cause of death was hypertension during pregnancy (31.2%) followed by acute liver steatosis during pregnancy (25%). In the previous study, published in 2003 in the same institution4, the mortality rate was 129 per 100,000 live births, and most deaths were related to direct obstetric causes (62%). The main causes of death in this period were due to hypertensive complications (17.2%), followed by postcesarean infection (16%).
Conclusion
Compared with data before the decade of 2000, there was an important reduction in maternal deaths due to infectious causes.
Key-words acute fatty liver of pregnancyMaternal mortalitymaternal mortality ratiopostcesarean infectionpregnancy hypertensionpregnancy-related deathSeptic abortionsevere maternal morbiditySee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Janete Vettorazzi
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Review Article
Relation between Selenium and Female Fertility: A Systematic Review
- Luiz Gustavo Lima
,
- André Amaro Mamédio dos Santos
,
- Tiago Daniel Gueiber
,
- Ricardo Zanetti Gomes
,
- Camila Marinelli Martins
,
[ … ], - Andrielle Cristina Chaikoski
06-03-2022
Views254This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleRelation between Selenium and Female Fertility: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(7):701-709
06-03-2022- Luiz Gustavo Lima
,
- André Amaro Mamédio dos Santos
,
- Tiago Daniel Gueiber
,
- Ricardo Zanetti Gomes
,
- Camila Marinelli Martins
,
- Andrielle Cristina Chaikoski
Views254See moreAbstract
Objective
To analyze the influence of selenium in female fertility.
Conclusion
Selenium supplementation is promising in women with this micronutrient deficiency to promote improvement of the reproductive efficiency and prevent damage to the pregnancy. Further studies on this theme are still required.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Luiz Gustavo Lima
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Review Article
Clinical Features and Maternal-fetal Results of Pregnant Women in COVID-19 Times
- Ana Paula Nogueira Godoi
,
- Gilcelia Correia Santos Bernardes
,
- Leilismara Sousa Nogueira
,
- Patrícia Nessralla Alpoim
,
- Melina de Barros Pinheiro
07-30-2021
Views237This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleClinical Features and Maternal-fetal Results of Pregnant Women in COVID-19 Times
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):384-394
07-30-2021- Ana Paula Nogueira Godoi
,
- Gilcelia Correia Santos Bernardes
,
- Leilismara Sousa Nogueira
,
- Patrícia Nessralla Alpoim
,
- Melina de Barros Pinheiro
Views237See moreAbstract
Objective
Coronavirus disease 2019 (COVID-19) is a disease caused by a newly discovered coronavirus, severe acute respiratory syndrome coronavirus 2 (SARSCoV-2), which usually leads to non-specific respiratory symptoms. Although pregnant women are considered at risk for respiratory infections by other viruses, such as SARS and Middle East respiratory syndrome (MERS), little is known about their vulnerability to SARS-CoV-2. Therefore, this study aims to identify and present the main studies on the topic, including the postpartum period.
Methods
In this narrative review, articles were searched in various databases, organizations, and health entities using keywords compatible with medical subject headings (MeSH), such as: COVID-19, pregnancy, vertical transmission, coronavirus 2019, and SARS-CoV-2.
Results
The review of the scientific literature on the subject revealed that pregnant women with COVID-19 did not present clinical manifestations significantly different from those of non-pregnant women; however, there are contraindicated therapies. Regarding fetuses, studies were identified that reported that infection by SARS-CoV-2 in pregnant women can cause fetal distress, breathing difficulties and premature birth, but there is no substantial evidence of vertical transmission.
Conclusion
Due to the lack of adequate information and the limitations of the analyzed studies, it is necessary to provide detailed clinical data on pregnant women infected with SARS-CoV-2 and on the maternal-fetal repercussions caused by this infection. Thus, this review may contribute to expand the knowledge of professionals working in the area as well as to guide more advanced studies on the risk related to pregnant women and their newborns. Meanwhile, monitoring of confirmed or suspected pregnant women with COVID-19 is essential, including in the postpartum period.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Ana Paula Nogueira Godoi
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Original Article
Levels and Predictors of Anxiety and Depression in Turkish PregnantWoman During the Covid-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):100-108
04-08-2022
Views174This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleLevels and Predictors of Anxiety and Depression in Turkish PregnantWoman During the Covid-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):100-108
04-08-2022Views174See moreAbstract
Objective
In addition to being a medical phenomenon, pandemics affect the individual and society on several levels and lead to disruptions. In the pandemic process, different groups in the population, including pregnant women as a defenseless group, are subjected to psychological threat. The present study aimed to determine the levels of anxiety and depression and related factors in pregnant women during the the coronavirus disease 2019 (Covid-19) pandemic.
Methods
The present cross-sectional study was conducted with 269 pregnant women through face-to-face interviews held in Istanbul, Turkey. Regarding the data collection tools, the Cronbach α reliability coefficient was of 0.90 for the Beck Anxiety Inventory, and of 0.85 for the Beck Depression Inventory.
Results
Among the participating pregnant women, 30.5% had mild, 17.5% had moderate, and 5.9% had severe anxiety symptoms, whereas 35.3% had mild, 16.7% had moderate, and 2.2% had severe depression symptoms. We found that those who were concerned about their health had 5.36 times (p=0.04) more risk of developing anxiety, and 4.82 times (p=0.01) more risk of developing depression than those who were not concerned. Those who had a history of psychiatric disease had 3.92 times (p=0.02) more risk of developing anxiety than those without it.
Conclusion
We determined that about half of the pregnant women included in the study had some degree of anxiety and depression during the COVID-19 pandemic. The risk factors for anxiety and depression among the pregnant women were determined as smoking, concerns about health and getting infectedwith the coronavirus, history of psychiatric disease, and undergoing regular antenatal care.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article
Risk Factors Associated with Uterine Rupture and Dehiscence: A Cross-Sectional Canadian Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(11):820-825
01-12-2021
Views182This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleRisk Factors Associated with Uterine Rupture and Dehiscence: A Cross-Sectional Canadian Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(11):820-825
01-12-2021Views182See moreAbstract
Objective
To compare maternal and perinatal risk factors associated with complete uterine rupture and uterine dehiscence.
Methods
Cross-sectional study of patients with uterine rupture/dehiscence from January 1998 to December 2017 (30 years) admitted at the Labor and Delivery Unit of a tertiary teaching hospital in Canada.
Results
There were 174 (0.1%) cases of uterine disruption (29 ruptures and 145 cases of dehiscence) out of 169,356 deliveries. There were associations between dehiscence and multiparity (odds ratio [OR]: 3.2; p=0.02), elevated maternal body mass index (BMI; OR: 3.4; p=0.02), attempt of vaginal birth after a cesarian section (OR: 2.9; p=0.05) and 5-minute low Apgar score (OR: 5.9; p<0.001). Uterine rupture was associated with preterm deliveries (36.5 ± 4.9 versus 38.2 ± 2.9; p=0.006), postpartum hemorrhage (OR: 13.9; p<0.001), hysterectomy (OR: 23.0; p=0.002), and stillbirth (OR: 8.2; p<0.001). There were no associations between uterine rupture and maternal age, gestational age, onset of labor, spontaneous or artificial rupture of membranes, use of oxytocin, type of uterine incision, and birthweight.
Conclusion
This large cohort demonstrated that there are different risk factors associated with either uterine rupture or dehiscence. Uterine rupture still represents a great threat to fetal-maternal health and, differently from the common belief, uterine dehiscence can also compromise perinatal outcomes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Editorial
Placenta Accreta Spectrum Disorders and Cesarean Scar Pregnancy Screening: Are we Asking the Right Questions?
- Conrado Milani Coutinho
,
- Laure Noel
,
- Veronica Giorgione
,
- Lígia Conceição Assef Marçal
,
- Amar Bhide
,
[ … ], - Basky Thilaganathan
07-30-2021
Views150This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
EditorialPlacenta Accreta Spectrum Disorders and Cesarean Scar Pregnancy Screening: Are we Asking the Right Questions?
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):347-350
07-30-2021- Conrado Milani Coutinho
,
- Laure Noel
,
- Veronica Giorgione
,
- Lígia Conceição Assef Marçal
,
- Amar Bhide
,
- Basky Thilaganathan
Views150What are the Relevant Risk Factors for Pas Screening?Numeroushistorical risk factors have been associated with the occurrence of PAS, including maternal obesity, advanced maternal age and parity, previous uterine surgery (including illegal terminations of pregnancy), and use of assisted reproductive technologies. However, there is no doubt that the concomitance of the only risk factor related […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Conrado Milani Coutinho
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Review Article
Main Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review
- Camilla Olivares Figueira
,
- Fernanda Garanhani Surita
,
- Kleber Fertrin
,
- Guilherme de Moraes Nobrega
,
- Maria Laura Costa
02-09-2022
Views247This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleMain Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(6):593-601
02-09-2022- Camilla Olivares Figueira
,
- Fernanda Garanhani Surita
,
- Kleber Fertrin
,
- Guilherme de Moraes Nobrega
,
- Maria Laura Costa
Views247See moreAbstract
Sickle cell disease (SCD) is the most common monogenic disease worldwide, with a variable prevalence in each continent. A single nucleotide substitution leads to an amino-acid change in the β-globin chain, altering the normal structure of hemoglobin, which is then called hemoglobin S inherited in homozygosity (HbSS) or double heterozygosity (HbSC, HbSβ), and leads to chronic hemolysis, vaso-occlusion, inflammation, and endothelium activation. Pregnant women with SCD are at a higher risk of developing maternal and perinatal complications. We performed a narrative review of the literature considering SCD and pregnancy, the main clinical and obstetrical complications, the specific antenatal care, and the follow-up for maternal and fetal surveillance. Pregnant women with SCD are at a higher risk of developing clinical and obstetric complications such as pain episodes, pulmonary complications, infections, thromboembolic events, preeclampsia, and maternal death. Their newborns are also at an increased risk of developing neonatal complications: fetal growth restriction, preterm birth, stillbirth. Severe complications can occur in patients of any genotype. We concluded that SCD is a high-risk condition that increases maternal and perinatal morbidity and mortality. A multidisciplinary approach during pregnancy and the postpartum period is key to adequately diagnose and treat complications.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Camilla Olivares Figueira
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