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  • Original Article

    Performance of Cervical Canal and Vaginal Cul-de-sac Samples for the Diagnosis of Cervical Neoplasia

    Rev Bras Ginecol Obstet. 2000;22(3):129-134

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    Original Article

    Performance of Cervical Canal and Vaginal Cul-de-sac Samples for the Diagnosis of Cervical Neoplasia

    Rev Bras Ginecol Obstet. 2000;22(3):129-134

    DOI 10.1590/S0100-72032000000300002

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    Purpose: to compare the performance of cervical canal and vaginal cul-de-sac samples for colpocytology testing, in order to diagnose cervical neoplasia. Methods: three sequential groups were constituted: group 1 - 10,048 women with ectocervix and cul-de-sac samples collected with the use of an Ayre spatula; group 2 - 3,847 women with ectocervix, cul-de-sac and cervical canal samples taken with an Ayre spatula and a cytobrush, and group 3 -- 4,059 women with ectocervix and cervical canal samples, using an Ayre spatula and a cytobrush. ANOVA (analysis of variance) and comparison of proportions were utilized for the statistical analysis. Results: the rates of abnormal tests in groups 2 (2.6%) and 3 (2.4%), including all squamous and glandular lesions, were significantly higher than in group 1 (2.0%). The diagnosis rates of low-grade squamous intraepithelial lesion (LGSIL) were not statistically different between the three groups (1.27, 1.25 and 1.07%). On the other hand, the diagnosis rates of high-grade squamous intraepithelial lesion (HGSIL) were statistically higher in groups 2 (0.81%) and 3 (0.77%) than in group 1 (0.54%). The difference between the rates of the second and the third groups did not present any statistical significance. Conclusions: the cervical canal sampling improves the performance of cytologic testing for the diagnosis of HGSIL, while cul-de-sac sampling does not change significantly the performance in diagnosing cervical neoplasia.

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    Performance of Cervical Canal and Vaginal Cul-de-sac Samples for the Diagnosis of Cervical Neoplasia

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