Original Article Archives - Page 3 of 53 - Revista Brasileira de Ginecologia e Obstetrícia

  • Original Article

    Validation of Brazilian Version of the Sexual Desire Inventory 2 (SDI-2)

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo78

    Summary

    Original Article

    Validation of Brazilian Version of the Sexual Desire Inventory 2 (SDI-2)

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo78

    DOI 10.61622/rbgo/2024rbgo78

    Views81

    ABSTRACT

    Objective:

    To traslate and validate of the Brazilian version of the SDI-2.

    Methods:

    This was a cross-sectional study. The cultural adaptation considered the stages of initial translation, synthesis of translations, evaluation by a committee of experts from different regions of Brazil, back-translation, and pre-test. The content validity and psychometric proprieties was assessed.

    Results:

    Ten specialists participated in the cultural adaptation of the SDI-2. The content validity showed a Content Validity Ratio (CVR) ≥ 0.75 (p = 0.05). A total of 674 subjects participated in the field study. The Exploratory Factorial Analysis (EFA) presented factor loads ≥ 0.445, and commonalities ≥ 0.40; and two dimensions represented 77% of the total variance explained. The Confirmatory Factorial Analysis CFA presented X2/df = 4.265; the Root Mean Square Error of Approximation RMSEA = 0.110; the Non-Normed Fit Index NNFI = 0.946; the Comparative Fit Index (CFI) = 0.963; the Goodness of Fit Index GFI = 0.986; and the Adjusted Goodness of Fit Index AGFI = 0.979 for a two-factor model. The coefficient values for the total SDI-2 score were 0.91 for Cronbach's alpha, 0.91 for McDonald's Omega, and 0.97 for the Greatest Lower Bound GLB coefficients. The invariance between sexes was 0.01 for the ΔCFI and ΔRMSEA, showing model stability for these two populations.

    Conclusion:

    The Brazilian version of the SDI-2 is self-report, valid, reliable and invariant across sex.

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    Validation of Brazilian Version of the Sexual Desire Inventory 2 (SDI-2)
  • Original Article

    Assessment of risk factors associated with post-molar gestational trophoblastic neoplasia: a retrospective cohort

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo83

    Summary

    Original Article

    Assessment of risk factors associated with post-molar gestational trophoblastic neoplasia: a retrospective cohort

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo83

    DOI 10.61622/rbgo/2024rbgo83

    Views63

    ABSTRACT

    Objective:

    Evaluate the risk factors for the development of post-molar gestational trophoblastic neoplasia.

    Methods:

    Retrospective cohort study with 320 women with gestational trophoblastic disease (GTD) followed in a tertiary hospital from January 2005 to January 2020. Data referring to the women's sociodemographic profile, clinical, laboratory and treatment aspects and types of GTD were analyzed.

    Results:

    The mean age of women with the benign form was 26.4±8.6 years and with the malignant forms 26.9±8.5 years (p=0.536). Most women with malignant forms came from regions further away from reference center (p=0.012), had vesicle elimination at the time of diagnosis (p=0.028) and needed more than one uterine evacuation (p<0.001) when compared to the benign forms. There was no difference between laboratory tests in both forms. Being between 30 and 39 years old increased the chance of developing invasive mole by 2.5 (p=0.004; 95%CI:1.3–4.9) and coming from regions far from reference center by 4.01 (p=0.020; CI95%: 1.2-12.9). The women with the highest risk of malignant forms were those with the longest time of become normal on human gonadotrophic hormone (hCG) testing (each week the risk increases 1.3 times; p<0.001, 95%CI: 1.2-1.3).

    Conclusion:

    The prolonged hCG fall curve is the main indicator of an increased chance of GTN. Women from regions further away from reference center have a greater chance of developing malignant forms, probably due to the difficulty in accessing the reference center and, therefore, adequate follow-up that would allow early identification of more serious cases.

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    Assessment of risk factors associated with post-molar gestational trophoblastic neoplasia: a retrospective cohort
  • Original Article

    Access and adequacy of antenatal care in a city in Brazil during two phases of the COVID-19 pandemic

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo87

    Summary

    Original Article

    Access and adequacy of antenatal care in a city in Brazil during two phases of the COVID-19 pandemic

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo87

    DOI 10.61622/rbgo/2024rbgo87

    Views51

    Abstract

    Objective:

    To compare access and suitability of antenatal care between years 2020 and 2022 among postpartum individuals at a Hospital in Florianopolis, and evaluate factors associated with antenatal suitability.

    Methods:

    Observational, cross-sectional, and quantitative study carried out in 2022. Collected data were compared with the database of a previous similar study carried out in the same setting in 2020. Data were extracted from medical records and prenatal booklets, in addition to a face-to-face questionnaire. Adequacy was measured using the Carvalho and Novaes index and health access was qualitatively evaluated. Socio-demographic and antenatal variables were analyzed. A statistical significance level of 0.05 was considered. Open-ended questions were categorized for analysis.

    Results:

    395 postpartum individuals were included. Antenatal care was adequate for 48.6% in 2020 and 69.1% in 2022. Among the barriers to access, 56% reported difficulty in scheduling appointments and/or exams and 23% complained of reduced healthcare staff due to strikes, COVID-19, among others. Adequate antenatal care was associated with being pregnant in 2022, being referred to high-risk units (PNAR), and not reporting difficulties in access. Also, it was associated with twice the chance of investigation for gestational diabetes (GDM) and syphilis.

    Conclusion:

    The 2022 post-vaccination period showed higher antenatal adequacy. The main difficulty for postpartum individuals was scheduling appointments and/or exams. Having antenatal care in 2022, no reports of difficulty in access, and follow-up at a high-risk unit were associated with antenatal adequacy.

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  • Original Article

    Nipple-sparing mastectomy in young versus elderly patients

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo90

    Summary

    Original Article

    Nipple-sparing mastectomy in young versus elderly patients

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo90

    DOI 10.61622/rbgo/2024rbgo90

    Views53

    Abstract

    Objective:

    In this study, we compared indications and outcomes of 115 young (< 40 years) versus 40 elderly (> 60 years) patients undergoing nipple-sparing mastectomy (NSM) as risk-reducing surgery or for breast cancer (BC) treatment.

    Methods:

    Between January 2004 and December 2018, young and elderly patients undergoing NSM with complete data from at least 6 months of follow-up were included.

    Results:

    BC treatment was the main indication for NSM, observed in 85(73.9%) young versus 33(82.5%) elderly patients, followed by risk-reducing surgery in 30(26.1%) young versus 7(17.5%) elderly patients. Complication rates did not differ between the age groups. At a median follow-up of 43 months, the overall recurrence rate was higher in the younger cohort (p = 0.04). However, when stratified into local, locoregional, contralateral, and distant metastasis, no statistical difference was observed. During the follow-up, only 2(1.7%) young patients died.

    Conclusion:

    Our findings elucidate a higher recurrence rate of breast cancer in younger patients undergoing NSM, which may correlate with the fact that age is an independent prognostic factor. High overall survival and low complication rates were evidenced in the two groups showing the safety of NSM for young and elderly patients.

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    Nipple-sparing mastectomy in young versus elderly patients
  • Original Article

    The role of HIV as an independent risk factor to cervical HSIL recurrence

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo85

    Summary

    Original Article

    The role of HIV as an independent risk factor to cervical HSIL recurrence

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo85

    DOI 10.61622/rbgo/2024rbgo85

    Views67

    ABSTRACT

    Objective:

    To evaluate the role of being human immunodeficiency virus (HIV) positive for predicting the risk of recurrence in women with a cervical high grade squamous intraepithelial lesion (HSIL) diagnosis.

    Methods:

    Retrospective observational case-control study, comprising HIV positive (case) and HIV negative (control) women in a 1:4 ratio. Women assisted by the Erasto Gaertner Hospital, between 2009-2018, with cervical HSIL diagnosis, submitted to treatment by Loop electrosurgical excision procedure (LEEP), and with a minimum follow-up of 18 months, were included. The immunological status, number and time to recurrence were analyzed, with p<0.05 considered significant. In a second analysis, only patients with free margins were evaluated.

    Results:

    The sample consisted of 320 women (64 cases and 256 controls). Presence of HIV, CD4 levels <200 and detectable viral load (CV) were associated with high risk of recurrence, with odds ratio (OR) of 5.4 (p<0.001/95CI:2.8-10); 3.6 (p<0.001 /IC95:0.6-21.1) and 1.8 (p=0.039 /IC95:0.3-9.3), respectively. In the sample with free margins (n=271), this risk was also higher among seropositive patients, with OR 4.18 (p=0.001/95CI:1.8-9.2).

    Conclusion:

    HIV is an independent risk factor for cervical HSIL recurrence and reduced disease-free survival time. Glandular involvement, compromised margins, undetectable CV and CD4<200 also increase the risk of relapse.

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  • Original Article

    Multidisciplinary team training in postpartum hemorrhage: impact on the use of blood products

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo67

    Summary

    Original Article

    Multidisciplinary team training in postpartum hemorrhage: impact on the use of blood products

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo67

    DOI 10.61622/rbgo/2024rbgo67

    Views63

    Abstract

    Objective

    Compare the number of puerperal women submitted to blood transfusion before and after the implementation of a care protocol for postpartum hemorrhage (PPH) with multidisciplinary team training.

    Methods

    Cross-sectional study in a university hospital, analyzing births from 2015 to 2019, compared the use of blood products before and after the adoption of a PPH protocol with multidisciplinary training.

    Results

    Between 2015 and 2019, there were 17,731 births, with 299 (1.7%) postpartum women receiving blood products and 278 postpartum women were considered for this analysis, 128 (0.7%) at Time 1 and 150 (0.8%) at Time 2. After the multiprofessional team training (T2), there was a difference in the complete use of the PPH protocol (use of oxytocin, misoprostol and tranexamic acid) (T1 = 5.1% x T2 = 49.5%, p≤0.0001). An individual categorized analysis revealed that, in the T2 period, there was lower use of blood component units per patient compared to T1 (Mann-Whitney, p=0.006). It should be noted that at T1 and T2, 54% and 24% respectively received two units of blood products. It is important to highlight that after the multidisciplinary team training for the PPH protocol, the goal of zero maternal death due to hemorrhage was reached.

    Conclusion

    The adoption of a specific protocol for PPH, combined with the training of a multidisciplinary team, had an impact on the ability to identify women at high risk of hemorrhage, resulting in a decrease in the use of blood components.

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    Multidisciplinary team training in postpartum hemorrhage: impact on the use of blood products
  • Original Article

    A new screening of preterm birth in gestation with short cervix after pessary plus progesterone

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo39i

    Summary

    Original Article

    A new screening of preterm birth in gestation with short cervix after pessary plus progesterone

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo39i

    DOI 10.61622/rbgo/2024rbgo39i

    Views125

    Abstract

    Objective

    This study aims to create a new screening for preterm birth < 34 weeks after gestation with a cervical length (CL) ≤ 30 mm, based on clinical, demographic, and sonographic characteristics.

    Methods

    This is a post hoc analysis of a randomized clinical trial (RCT), which included pregnancies, in middle-gestation, screened with transvaginal ultrasound. After observing inclusion criteria, the patient was invited to compare pessary plus progesterone (PP) versus progesterone only (P) (1:1). The objective was to determine which variables were associated with severe preterm birth using logistic regression (LR). The area under the curve (AUC), sensitivity, specificity, and positive predictive value (PPV) and negative predictive value (NPV) were calculated for both groups after applying LR, with a false positive rate (FPR) set at 10%.

    Results

    The RCT included 936 patients, 475 in PP and 461 in P. The LR selected: ethnics white, absence of previous curettage, previous preterm birth, singleton gestation, precocious identification of short cervix, CL < 14.7 mm, CL in curve > 21.0 mm. The AUC (CI95%), sensitivity, specificity, PPV, and PNV, with 10% of FPR, were respectively 0.978 (0.961-0.995), 83.4%, 98.1%, 83.4% and 98.1% for PP < 34 weeks; and 0.765 (0.665-0.864), 38.7%, 92.1%, 26.1% and 95.4%, for P < 28 weeks.

    Conclusion

    Logistic regression can be effective to screen preterm birth < 34 weeks in patients in the PP Group and all pregnancies with CL ≤ 30 mm.

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    A new screening of preterm birth in gestation with short cervix after pessary plus progesterone
  • Original Article

    Association between dietary patterns and infant birth weight in brazilian pregnancy women with gestational diabetes: a cross-sectional study

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo68

    Summary

    Original Article

    Association between dietary patterns and infant birth weight in brazilian pregnancy women with gestational diabetes: a cross-sectional study

    Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo68

    DOI 10.61622/rbgo/2024rbgo68

    Views71

    Abstract

    Objective

    To evaluate the association between the dietary patterns (DPs) of pregnant women with GDM (gestational diabetes mellitus) and the birth weight (BW) of the infants.

    Methods

    Cross-sectional study with 187 adult pregnant women with GDM attended at a maternity in Rio de Janeiro from 2011 to 2014. Dietary intake was assessed in the third trimester using a semiquantitative food frequency questionnaire (FFQ). The outcomes were BW and weight adequacy for gestational age (GA). Reduced Rank Regression (RRR) was used to explain the following response variables: density of carbohydrates, fibres, and saturated fatty acids. Statistical analyzes included multinomial logistic regression models.

    Results

    The mean BW was 3261.9 (± 424.5) g. Three DPs were identified, with DP 3 (high consumption of refined carbohydrates, fast foods/snacks, whole milk, sugars/sweets, and soft drinks and low consumption of beans, vegetables, and low-fat milk and derivatives) being the main pattern, explaining 48.37% of the response variables. In the multinomial logistic regression analysis no statistically significant association was found between the tertiles of DPs and BW or the adequacy of weight for GA, even after adjustments of confounding covariates.

    Conclusion

    No significant associations were found between maternal DPs in the third trimester of pregnancy and infant BW or adequacy of weight for GA.

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    Association between dietary patterns and infant birth weight in brazilian pregnancy women with gestational diabetes: a cross-sectional study

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