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Original Article07-22-2019
Estimation of the Costs of Invasive Cervical Cancer Treatment in Brazil: A Micro-Costing Study
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(6):387-393
Abstract
Original ArticleEstimation of the Costs of Invasive Cervical Cancer Treatment in Brazil: A Micro-Costing Study
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(6):387-393
Views163See moreAbstract
Objective
Themain objective of the present study was to estimate the annual treatment costs of invasive cervical cancer (ICC) per patient at an oncology center in Brazil from a societal perspective by considering direct medical, direct nonmedical, and indirect costs.
Methods
A cost analysis descriptive study, in which direct medical, direct nonmedical, and indirect costs were collected using a microcosting approach, was conducted between May 2014 and July 2016 from a societal perspective. The study population consisted of women diagnosed with ICC admitted to a tertiary hospital in Recife, state of Pernambuco, Brazil. The annual cost per patient was estimated in terms of the value of American Dollars (US$) in 2016.
Results
From a societal perspective, the annual ICC treatment cost per patient was US $ 2,219.73. Direct medical costs were responsible for 81.2% of the total value, of which radiotherapy and outpatient chemotherapy had the largest share. Under the base-case assumption, the estimated cost to the national budget of a year of ICC treatment in the Brazilian population was US$ 25,954,195.04.
Conclusion
We found a high economic impact of health care systems treating ICC in a poor region of Brazil. These estimates could be applicable to further evaluations of the cost-effectiveness of preventing and treating ICC.
Views163
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleEstimation of the Costs of Invasive Cervical Cancer Treatment in Brazil: A Micro-Costing Study
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(6):387-393
Views163See moreAbstract
Objective
Themain objective of the present study was to estimate the annual treatment costs of invasive cervical cancer (ICC) per patient at an oncology center in Brazil from a societal perspective by considering direct medical, direct nonmedical, and indirect costs.
Methods
A cost analysis descriptive study, in which direct medical, direct nonmedical, and indirect costs were collected using a microcosting approach, was conducted between May 2014 and July 2016 from a societal perspective. The study population consisted of women diagnosed with ICC admitted to a tertiary hospital in Recife, state of Pernambuco, Brazil. The annual cost per patient was estimated in terms of the value of American Dollars (US$) in 2016.
Results
From a societal perspective, the annual ICC treatment cost per patient was US $ 2,219.73. Direct medical costs were responsible for 81.2% of the total value, of which radiotherapy and outpatient chemotherapy had the largest share. Under the base-case assumption, the estimated cost to the national budget of a year of ICC treatment in the Brazilian population was US$ 25,954,195.04.
Conclusion
We found a high economic impact of health care systems treating ICC in a poor region of Brazil. These estimates could be applicable to further evaluations of the cost-effectiveness of preventing and treating ICC.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article07-22-2019
Interest In and Practices Related to Gynecologic Oncology among Members of the Brazilian Federation of Associations of Gynecology and Obstetrics
- Arilto Eleutério da Silva Júnior,
- Jesus Paula Carvalho,
- Sophie Françoise Mauricette Derchain,
- Angélica Nogueira Rodrigues,
- Renato Moretti, [ ... ],
- Agnaldo Lopes da Silva Filho
Abstract
Original ArticleInterest In and Practices Related to Gynecologic Oncology among Members of the Brazilian Federation of Associations of Gynecology and Obstetrics
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(6):394-399
- Arilto Eleutério da Silva Júnior,
- Jesus Paula Carvalho,
- Sophie Françoise Mauricette Derchain,
- Angélica Nogueira Rodrigues,
- Renato Moretti,
- Eduardo Batista Cândido,
- Ricardo dos Reis,
- Aline Evangelista Santiago,
- Agnaldo Lopes da Silva Filho
Views149See moreAbstract
Objective
The present study aims to obtain basic demographic information, the level of interest and of training in gynecology oncology among Brazilian obstetricians and gynecologists (OB-GYNs) to create a professional profile.
Methods
An online questionnaire was sent to 16,008 gynecologists affiliated to the Brazilian Federation of Associations of Gynecology and Obstetrics (FEBRASGO, in the Portuguese acronym). We considered gynecologists dedicated to gynecologic oncology (OB-GYNs ONCO) those who self-reported that > 50% of their daily practice consists in working with women’s cancer care.
Results
A total of 1,608 (10%) of 16,008 FEBRASGO members responded. The OBGYNs are concentrated in the southern and southeastern states of Brazil. Gynecologic oncology was considered the 8th greatest area of interest in gynecology among the OBGYNs. A total of 95 (5.9%) of the OB-GYNs were considered OB-GYNs ONCO. Obstetricians and gynecologists are actively engaged in cancer care: > 60% of them dedicate up to 25% of their daily practice to oncology. The role of the physicians in screening and prevention, diagnosis, in the treatment of precancerous lesions, and in low complexity surgical procedures is notably high. Gynecologists dedicated to gynecologic oncology in Brazil have a heterogeneous, nonstandardized and short training period in gynecologic oncology. These professionals had a more significantly role in performing medium- and high-complexity operations compared with OB-GYNs (65.2% versus 34%, and 47.3% versus 8.4%, respectively).
Conclusion
The role of OB-GYNs and of OB-GYNs ONCO appears to be complementary. Obstetricians and gynecologists actmore often in screening and prevention and in low-complexity surgical procedures, whereas OB-GYNs ONCO are more involved in highly complex cases. Strategies to raise standards in cancer training and to encourage the recognition of gynecologic oncology as a subspecialty should be adopted in Brazil.
Views149This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleInterest In and Practices Related to Gynecologic Oncology among Members of the Brazilian Federation of Associations of Gynecology and Obstetrics
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(6):394-399
- Arilto Eleutério da Silva Júnior,
- Jesus Paula Carvalho,
- Sophie Françoise Mauricette Derchain,
- Angélica Nogueira Rodrigues,
- Renato Moretti,
- Eduardo Batista Cândido,
- Ricardo dos Reis,
- Aline Evangelista Santiago,
- Agnaldo Lopes da Silva Filho
Views149See moreAbstract
Objective
The present study aims to obtain basic demographic information, the level of interest and of training in gynecology oncology among Brazilian obstetricians and gynecologists (OB-GYNs) to create a professional profile.
Methods
An online questionnaire was sent to 16,008 gynecologists affiliated to the Brazilian Federation of Associations of Gynecology and Obstetrics (FEBRASGO, in the Portuguese acronym). We considered gynecologists dedicated to gynecologic oncology (OB-GYNs ONCO) those who self-reported that > 50% of their daily practice consists in working with women’s cancer care.
Results
A total of 1,608 (10%) of 16,008 FEBRASGO members responded. The OBGYNs are concentrated in the southern and southeastern states of Brazil. Gynecologic oncology was considered the 8th greatest area of interest in gynecology among the OBGYNs. A total of 95 (5.9%) of the OB-GYNs were considered OB-GYNs ONCO. Obstetricians and gynecologists are actively engaged in cancer care: > 60% of them dedicate up to 25% of their daily practice to oncology. The role of the physicians in screening and prevention, diagnosis, in the treatment of precancerous lesions, and in low complexity surgical procedures is notably high. Gynecologists dedicated to gynecologic oncology in Brazil have a heterogeneous, nonstandardized and short training period in gynecologic oncology. These professionals had a more significantly role in performing medium- and high-complexity operations compared with OB-GYNs (65.2% versus 34%, and 47.3% versus 8.4%, respectively).
Conclusion
The role of OB-GYNs and of OB-GYNs ONCO appears to be complementary. Obstetricians and gynecologists actmore often in screening and prevention and in low-complexity surgical procedures, whereas OB-GYNs ONCO are more involved in highly complex cases. Strategies to raise standards in cancer training and to encourage the recognition of gynecologic oncology as a subspecialty should be adopted in Brazil.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article06-27-2019
Prevalence and Association of Congenital Anomalies According to the Maternal Body Mass Index: Cross-Sectional Study
- Carolina Leão de Moraes ,
- Carolina Rodrigues Mendonça,
- Natália Cruz e Melo,
- Waldemar Naves do Amaral
Abstract
Original ArticlePrevalence and Association of Congenital Anomalies According to the Maternal Body Mass Index: Cross-Sectional Study
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):280-290
- Carolina Leão de Moraes ,
- Carolina Rodrigues Mendonça,
- Natália Cruz e Melo,
- Waldemar Naves do Amaral
Views190See moreAbstract
Objective
To evaluate and compare the prevalence of structural congenital anomalies (CAs) according to maternal body mass index (BMI).
Methods
The present cross-sectional study involved pregnant women with fetuses diagnosed with structural CAs through morphological ultrasonography between November 2014 and January 2016. The nutritional status of the pregnant women was classified according to the gross value of the body mass index. The pregnant women were categorized into four groups: low weight, adequate weight, overweight, and obesity. Statistical analysis was performed using Stata/SE version 12.0 (Stata Corporation, College Station, TX), with values of p ≤ 0.05 considered statistically significant.
Results
A total of 223 pregnant women had fetuses diagnosed with CAs. The prevalence of structural CAs in pregnant women with lowweight was of 20.18%, of 43.50% in pregnant women with adequate weight, of 22.87% in pregnant women with overweight, and of 13.45% in pregnant women with obesity. The prevalence of central nervous system (CNS) anomalies and of genitourinary systemanomalieswas high for the four groups of pregnant women. A positive association was observed between multiple anomalies in pregnant women with adequate weight (prevalence ratio [PR] = 1.65; p ≤ 0.004) and between anomalies of the lymphatic system in obese pregnant women (PR = 4.04, p ≤ 0.000).
Conclusion
The prevalence of CNS and genitourinary systemanomalies was high in all of the BMI categories. Obese pregnancies were associated with lymphatic system anomalies. Therefore, screening and identification of the risk factors for CAs are important, regardless of the maternal BMI. Our findings reinforce the importance of discussing with pregnant women maternal nutrition and its effect on fetal development and on neonatal outcome.
Views190This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePrevalence and Association of Congenital Anomalies According to the Maternal Body Mass Index: Cross-Sectional Study
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):280-290
- Carolina Leão de Moraes ,
- Carolina Rodrigues Mendonça,
- Natália Cruz e Melo,
- Waldemar Naves do Amaral
Views190See moreAbstract
Objective
To evaluate and compare the prevalence of structural congenital anomalies (CAs) according to maternal body mass index (BMI).
Methods
The present cross-sectional study involved pregnant women with fetuses diagnosed with structural CAs through morphological ultrasonography between November 2014 and January 2016. The nutritional status of the pregnant women was classified according to the gross value of the body mass index. The pregnant women were categorized into four groups: low weight, adequate weight, overweight, and obesity. Statistical analysis was performed using Stata/SE version 12.0 (Stata Corporation, College Station, TX), with values of p ≤ 0.05 considered statistically significant.
Results
A total of 223 pregnant women had fetuses diagnosed with CAs. The prevalence of structural CAs in pregnant women with lowweight was of 20.18%, of 43.50% in pregnant women with adequate weight, of 22.87% in pregnant women with overweight, and of 13.45% in pregnant women with obesity. The prevalence of central nervous system (CNS) anomalies and of genitourinary systemanomalieswas high for the four groups of pregnant women. A positive association was observed between multiple anomalies in pregnant women with adequate weight (prevalence ratio [PR] = 1.65; p ≤ 0.004) and between anomalies of the lymphatic system in obese pregnant women (PR = 4.04, p ≤ 0.000).
Conclusion
The prevalence of CNS and genitourinary systemanomalies was high in all of the BMI categories. Obese pregnancies were associated with lymphatic system anomalies. Therefore, screening and identification of the risk factors for CAs are important, regardless of the maternal BMI. Our findings reinforce the importance of discussing with pregnant women maternal nutrition and its effect on fetal development and on neonatal outcome.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Carolina Leão de Moraes
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Original Article06-27-2019
Knowledge of Pregnant Adolescents about Human Papillomavirus
- Erika Zambrano Tanaka ,
- Sílvia Souza Kamizaki,
- Silvana Maria Quintana,
- Rodolfo de Carvalho Pacagnella,
- Fernanda Garanhani Surita
Abstract
Original ArticleKnowledge of Pregnant Adolescents about Human Papillomavirus
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):291-297
- Erika Zambrano Tanaka ,
- Sílvia Souza Kamizaki,
- Silvana Maria Quintana,
- Rodolfo de Carvalho Pacagnella,
- Fernanda Garanhani Surita
Views165See moreAbstract
Objective
To evaluate the level of information possessed by pregnant adolescents regarding the human papillomavirus (HPV).
Methods
Descriptive study developed in the adolescent prenatal outpatient clinic of a tertiary hospital fromthe state of São Paulo, Brazil. Data were collected between June and December 2017 following approval from the ethics and research committee (CAAE: 1.887.892/2017). Pregnant adolescents, ≤18 years old, who attended the abovementioned outpatient section, composed the sample. Those diagnosed with a psychiatric disorder and those with hearing or cognitive disabilities were excluded. After acceptance to participate in the present study, the pregnant adolescents signed an Informed Consent Form. Regarding the statistical analysis, the chi-squared test and the Fisher exact test were used.
Results
Regarding the knowledge about HPV, 123 (80.92%) of the participants had already heard about the subject; for 77 (50.66%), their schools had been the source of the information; 101 (66.45%) did not know how they could be infected by the virus. Age variation did not influence their knowledge on how to prevent themselves from HPV (p = 0.2562). The variable vaccine is associated with HPV prevention (p < 0.0001).
Conclusion
The pregnant adolescents composing the sample have shown to have knowledge about HPV. However, they do not prevent themselves from it appropriately, given that little more than half of the sample was vaccinated, had not reported an understanding that the use of preservatives and vaccination are effective means of prevention, and did not correlate HPV with uterine cervical cancer.
Views165This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleKnowledge of Pregnant Adolescents about Human Papillomavirus
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):291-297
- Erika Zambrano Tanaka ,
- Sílvia Souza Kamizaki,
- Silvana Maria Quintana,
- Rodolfo de Carvalho Pacagnella,
- Fernanda Garanhani Surita
Views165See moreAbstract
Objective
To evaluate the level of information possessed by pregnant adolescents regarding the human papillomavirus (HPV).
Methods
Descriptive study developed in the adolescent prenatal outpatient clinic of a tertiary hospital fromthe state of São Paulo, Brazil. Data were collected between June and December 2017 following approval from the ethics and research committee (CAAE: 1.887.892/2017). Pregnant adolescents, ≤18 years old, who attended the abovementioned outpatient section, composed the sample. Those diagnosed with a psychiatric disorder and those with hearing or cognitive disabilities were excluded. After acceptance to participate in the present study, the pregnant adolescents signed an Informed Consent Form. Regarding the statistical analysis, the chi-squared test and the Fisher exact test were used.
Results
Regarding the knowledge about HPV, 123 (80.92%) of the participants had already heard about the subject; for 77 (50.66%), their schools had been the source of the information; 101 (66.45%) did not know how they could be infected by the virus. Age variation did not influence their knowledge on how to prevent themselves from HPV (p = 0.2562). The variable vaccine is associated with HPV prevention (p < 0.0001).
Conclusion
The pregnant adolescents composing the sample have shown to have knowledge about HPV. However, they do not prevent themselves from it appropriately, given that little more than half of the sample was vaccinated, had not reported an understanding that the use of preservatives and vaccination are effective means of prevention, and did not correlate HPV with uterine cervical cancer.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Erika Zambrano Tanaka
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Original Article06-27-2019
Profile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns
- Maria da Glória Rodrigues Tavares ,
- Érika Sales Lopes,
- Rosy Anne de Jesus Pereira Araújo Barros,
- Rossana Santiago de Sousa Azulay,
- Manuel dos Santos Faria
Abstract
Original ArticleProfile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):298-305
- Maria da Glória Rodrigues Tavares ,
- Érika Sales Lopes,
- Rosy Anne de Jesus Pereira Araújo Barros,
- Rossana Santiago de Sousa Azulay,
- Manuel dos Santos Faria
Views155See moreAbstract
Objective
Gestational diabetes mellitus (GDM) is associated with a higher risk of perinatal morbidity and mortality, and its main complication is the occurrence of large for gestational age (LGA) newborns. The present study aims to characterize pregnant women with GDM and to identify factors associated with the occurrence of LGA newborns in this population.
Methods
A cross-sectional study was performed based on medical records of women whose prenatal care and delivery were performed at the Maternal and Child Unit of the HospitalUniversitário of theUniversidade Federal doMaranhão, state of Maranhão, Brazil.A total of 116 pregnant women diagnosed with GDMwere included according to the criteria of the International Association of Diabetes and Pregnancy Study Groups (IADPSG).
Results
The variables associated with LGA newborns after multivariate analysis were: obesity prior to pregnancy (OR = 11.6; 95% CI: 1.40-95.9), previous macrosomia (OR = 34.7; 95% CI: 4.08-295.3), high blood glucose levels in the 3rd trimester (OR = 2,67; 95% CI: 1.01-7.12) and combined change in the oral glucose tolerance test (OGTT) (fasting + postdextrose) (OR = 3.53;95%CI:1.25-14.2) = 1.17-10.6).Otherwise, insufficientweight gain during pregnancy reduced the risk for LGA newborns (OR = 0.04; 95% CI: 0.01-0.32).
Conclusion
Obesity prior to pregnancy, previous macrosomia, high blood glucose levels in the 3rd trimester, and combined change in the OGTT were independent predictive factors for LGA newborns in pregnant women with GDM.
Views155This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleProfile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):298-305
- Maria da Glória Rodrigues Tavares ,
- Érika Sales Lopes,
- Rosy Anne de Jesus Pereira Araújo Barros,
- Rossana Santiago de Sousa Azulay,
- Manuel dos Santos Faria
Views155See moreAbstract
Objective
Gestational diabetes mellitus (GDM) is associated with a higher risk of perinatal morbidity and mortality, and its main complication is the occurrence of large for gestational age (LGA) newborns. The present study aims to characterize pregnant women with GDM and to identify factors associated with the occurrence of LGA newborns in this population.
Methods
A cross-sectional study was performed based on medical records of women whose prenatal care and delivery were performed at the Maternal and Child Unit of the HospitalUniversitário of theUniversidade Federal doMaranhão, state of Maranhão, Brazil.A total of 116 pregnant women diagnosed with GDMwere included according to the criteria of the International Association of Diabetes and Pregnancy Study Groups (IADPSG).
Results
The variables associated with LGA newborns after multivariate analysis were: obesity prior to pregnancy (OR = 11.6; 95% CI: 1.40-95.9), previous macrosomia (OR = 34.7; 95% CI: 4.08-295.3), high blood glucose levels in the 3rd trimester (OR = 2,67; 95% CI: 1.01-7.12) and combined change in the oral glucose tolerance test (OGTT) (fasting + postdextrose) (OR = 3.53;95%CI:1.25-14.2) = 1.17-10.6).Otherwise, insufficientweight gain during pregnancy reduced the risk for LGA newborns (OR = 0.04; 95% CI: 0.01-0.32).
Conclusion
Obesity prior to pregnancy, previous macrosomia, high blood glucose levels in the 3rd trimester, and combined change in the OGTT were independent predictive factors for LGA newborns in pregnant women with GDM.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Maria da Glória Rodrigues Tavares
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Original Article06-27-2019
Laparoscopic Approach in Surgical Staging of Endometrial Cancer
- Mariana Mouraz ,
- Cátia Sofia Ferreira,
- Sónia Gonçalves,
- Nuno Nogueira Martins,
- Francisco Nogueira Martins
Abstract
Original ArticleLaparoscopic Approach in Surgical Staging of Endometrial Cancer
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):306-311
- Mariana Mouraz ,
- Cátia Sofia Ferreira,
- Sónia Gonçalves,
- Nuno Nogueira Martins,
- Francisco Nogueira Martins
Views195See moreAbstract
Objective
To compare laparoscopy with laparotomy for surgical staging of endometrial cancer.
Methods
A cohort of women with preoperative diagnosis of endometrial cancer who underwent surgical staging was retrospectively evaluated. The main study end points were: morbidity and mortality, hospital length of stay, perioperative adverse events and recurrence rate. Data analysis was performed with the software SPSS v25 (IBM Corp., Armonk, NY, USA), categorical variables using a Chi-square and Fisher test, and continuous variables using the Student t-test.
Results
Atotal of 162 patientswere analyzed. 138 patientsmet the inclusion criteria, 41of whom underwent staging by laparoscopy and 97 by laparotomy. Conversions from laparoscopy to laparotomy happened in 2 patients (4.9%) and were secondary to technical difficulties and poor exposure. Laparoscopy had fewer postoperative adverse events when compared with laparotomy (7.3% vs 23.7%, respectively; p = 0.005), but similar rates of intraoperative complications, despite having a significantly longer operative time (median, 175 vs 130 minutes, respectively; p < 0.001). Hospital stay was significantly lower in laparoscopy versus laparotomy patients (median, 3 vs 7 days, respectively; p < 0.001). No difference in recurrence or mortality rates were observed.
Conclusion
Laparoscopic surgical staging for endometrial cancer is feasible and safe. Patients have lower postoperative complication rates and shorter hospital stays when compared with the approach by laparotomy.
Views195This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleLaparoscopic Approach in Surgical Staging of Endometrial Cancer
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):306-311
- Mariana Mouraz ,
- Cátia Sofia Ferreira,
- Sónia Gonçalves,
- Nuno Nogueira Martins,
- Francisco Nogueira Martins
Views195See moreAbstract
Objective
To compare laparoscopy with laparotomy for surgical staging of endometrial cancer.
Methods
A cohort of women with preoperative diagnosis of endometrial cancer who underwent surgical staging was retrospectively evaluated. The main study end points were: morbidity and mortality, hospital length of stay, perioperative adverse events and recurrence rate. Data analysis was performed with the software SPSS v25 (IBM Corp., Armonk, NY, USA), categorical variables using a Chi-square and Fisher test, and continuous variables using the Student t-test.
Results
Atotal of 162 patientswere analyzed. 138 patientsmet the inclusion criteria, 41of whom underwent staging by laparoscopy and 97 by laparotomy. Conversions from laparoscopy to laparotomy happened in 2 patients (4.9%) and were secondary to technical difficulties and poor exposure. Laparoscopy had fewer postoperative adverse events when compared with laparotomy (7.3% vs 23.7%, respectively; p = 0.005), but similar rates of intraoperative complications, despite having a significantly longer operative time (median, 175 vs 130 minutes, respectively; p < 0.001). Hospital stay was significantly lower in laparoscopy versus laparotomy patients (median, 3 vs 7 days, respectively; p < 0.001). No difference in recurrence or mortality rates were observed.
Conclusion
Laparoscopic surgical staging for endometrial cancer is feasible and safe. Patients have lower postoperative complication rates and shorter hospital stays when compared with the approach by laparotomy.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Mariana Mouraz
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Original Article06-27-2019
Quality of Life among University Students with Premenstrual Syndrome
- Fernanda Figueira Victor,
- Ariani Impieri Souza,
- Cynthia Danúbia Tavares Barreiros,
- João Lucas Nunes de Barros,
- Flavia Anchielle Carvalho da Silva, [ ... ],
- Ana Laura Carneiro Gomes Ferreira
Abstract
Original ArticleQuality of Life among University Students with Premenstrual Syndrome
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):312-317
- Fernanda Figueira Victor,
- Ariani Impieri Souza,
- Cynthia Danúbia Tavares Barreiros,
- João Lucas Nunes de Barros,
- Flavia Anchielle Carvalho da Silva,
- Ana Laura Carneiro Gomes Ferreira
Views269Abstract
Objective
To evaluate the quality of life among university students with premenstrual syndrome (PMS).
Methods
The cross-sectional study was conducted at the Faculdade Pernambucana de Saúde, in Recife, Brazil, between August 2016 and July 2017. Sociodemographic, gynecological, and lifestyle variables, and PMS occurrence, were investigated among 642 students. The short form of the World Health Organization Quality of Life (WHOQOL Bref) questionnaire was used to evaluate four domains of the quality of life of the students: physical, mental, social relationships, and environmental. The American College of Obstetricians and Gynecologists’ criteria were used to define PMS.
Results
Of the 642 students, 49.9% had PMS, 23.3% had mild PMS and 26.6% had premenstrual dysphoric disorder (PMDD). Most of the students were between 18 and 24 years old, had regular menstrual cycles, and practiced physical activity. Regarding the physical and mental domains of the WHOQOL-Bref questionnaire, a statisticallysignificant difference was observed between the students who did not have and those who had mild or PMDD (p < 0.001). A difference was also found between the students who did not have PMS and those who had mild PMS in the social relationships (p = 0.001) and environmental domains (p = 0.009).
Conclusion
Mild PMS and PMDD are prevalent among university students on healthrelated courses, and the syndrome can affect the students’ self-assessment of all the domains of quality of life.
Key-words medical studentMenstruation disturbancespremenstrual dysphoric disorderPremenstrual syndromeQuality of lifeSee moreViews269This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleQuality of Life among University Students with Premenstrual Syndrome
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):312-317
- Fernanda Figueira Victor,
- Ariani Impieri Souza,
- Cynthia Danúbia Tavares Barreiros,
- João Lucas Nunes de Barros,
- Flavia Anchielle Carvalho da Silva,
- Ana Laura Carneiro Gomes Ferreira
Views269Abstract
Objective
To evaluate the quality of life among university students with premenstrual syndrome (PMS).
Methods
The cross-sectional study was conducted at the Faculdade Pernambucana de Saúde, in Recife, Brazil, between August 2016 and July 2017. Sociodemographic, gynecological, and lifestyle variables, and PMS occurrence, were investigated among 642 students. The short form of the World Health Organization Quality of Life (WHOQOL Bref) questionnaire was used to evaluate four domains of the quality of life of the students: physical, mental, social relationships, and environmental. The American College of Obstetricians and Gynecologists’ criteria were used to define PMS.
Results
Of the 642 students, 49.9% had PMS, 23.3% had mild PMS and 26.6% had premenstrual dysphoric disorder (PMDD). Most of the students were between 18 and 24 years old, had regular menstrual cycles, and practiced physical activity. Regarding the physical and mental domains of the WHOQOL-Bref questionnaire, a statisticallysignificant difference was observed between the students who did not have and those who had mild or PMDD (p < 0.001). A difference was also found between the students who did not have PMS and those who had mild PMS in the social relationships (p = 0.001) and environmental domains (p = 0.009).
Conclusion
Mild PMS and PMDD are prevalent among university students on healthrelated courses, and the syndrome can affect the students’ self-assessment of all the domains of quality of life.
Key-words medical studentMenstruation disturbancespremenstrual dysphoric disorderPremenstrual syndromeQuality of lifeSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article06-19-2019
Evaluation of Immunological Parameters in Pregnant Women: Low Levels of B and NK Cells
- Juliana Araújo de Carvalho Schettini ,
- Thomás Virgílio Gomes,
- Claudeir Dias da Silva Júnior,
- Sandra de Andrade Heráclio,
- Isabela Cristina Coutinho de Albuquerque Neiva Coelho, [ ... ],
- Leuridan Cavalcante Torres
Abstract
Original ArticleEvaluation of Immunological Parameters in Pregnant Women: Low Levels of B and NK Cells
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(4):213-219
- Juliana Araújo de Carvalho Schettini ,
- Thomás Virgílio Gomes,
- Claudeir Dias da Silva Júnior,
- Sandra de Andrade Heráclio,
- Isabela Cristina Coutinho de Albuquerque Neiva Coelho,
- Leuridan Cavalcante Torres
Views185See moreAbstract
Objective
To describe the immunological and hematological reference intervals of low-risk pregnant women.
Methods
A cross-sectional retrospective database analysis of a basic and translational study analyzing the hematological evaluation blood counts and immunophenotyping of TCD3 + , TCD4 + , TCD8 + , B, and natural killer (NK) cells of the peripheral blood in 79 low-risk pregnant women and of 30 control women from the state of Pernambuco, Brazil, was performed.
Results
No significant differences were detected between the hematological profiles of the 2nd and 3rd trimesters. Nevertheless, the median level of B cells decreased significantly in the 2nd (174 x 103 μL; p < 0.002) and 3rd trimesters (160 x 103 μL; p < 0.001), compared with the control group (296 x 103 μL). Similarly, the median level of NK cells was lower in the 2nd (134 x 103 μL; p < 0.0004) and 3rd trimesters (100 x 103 μL, p < 0.0004), compared with the control group (183 x 103 μL). In contrast, relative TCD4+ and TCD8+ levels increased in the 2nd and 3rd trimesters compared with the controls (TCD4 + : 2nd trimester = 59%; p < 0.001; 3rd trimester = 57%; p < 0.01; control = 50%; and TCD8 + : 2nd trimester = 31%; p < 0.001; 3rd trimester = 36%; p < 0.01; control = 24%).
Conclusion
Low-risk pregnant women have ~ 40% less B and NK cells in the peripheral blood, compared with non-pregnant women. These parameters may improve health assistance for mothers and contribute to define reference values for normal pregnancies.
Views185This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleEvaluation of Immunological Parameters in Pregnant Women: Low Levels of B and NK Cells
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(4):213-219
- Juliana Araújo de Carvalho Schettini ,
- Thomás Virgílio Gomes,
- Claudeir Dias da Silva Júnior,
- Sandra de Andrade Heráclio,
- Isabela Cristina Coutinho de Albuquerque Neiva Coelho,
- Leuridan Cavalcante Torres
Views185See moreAbstract
Objective
To describe the immunological and hematological reference intervals of low-risk pregnant women.
Methods
A cross-sectional retrospective database analysis of a basic and translational study analyzing the hematological evaluation blood counts and immunophenotyping of TCD3 + , TCD4 + , TCD8 + , B, and natural killer (NK) cells of the peripheral blood in 79 low-risk pregnant women and of 30 control women from the state of Pernambuco, Brazil, was performed.
Results
No significant differences were detected between the hematological profiles of the 2nd and 3rd trimesters. Nevertheless, the median level of B cells decreased significantly in the 2nd (174 x 103 μL; p < 0.002) and 3rd trimesters (160 x 103 μL; p < 0.001), compared with the control group (296 x 103 μL). Similarly, the median level of NK cells was lower in the 2nd (134 x 103 μL; p < 0.0004) and 3rd trimesters (100 x 103 μL, p < 0.0004), compared with the control group (183 x 103 μL). In contrast, relative TCD4+ and TCD8+ levels increased in the 2nd and 3rd trimesters compared with the controls (TCD4 + : 2nd trimester = 59%; p < 0.001; 3rd trimester = 57%; p < 0.01; control = 50%; and TCD8 + : 2nd trimester = 31%; p < 0.001; 3rd trimester = 36%; p < 0.01; control = 24%).
Conclusion
Low-risk pregnant women have ~ 40% less B and NK cells in the peripheral blood, compared with non-pregnant women. These parameters may improve health assistance for mothers and contribute to define reference values for normal pregnancies.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Juliana Araújo de Carvalho Schettini
Original Article Archives - Page 3 of 201 - Revista Brasileira de Ginecologia e Obstetrícia
