Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(6):255-261
DOI 10.1590/S0100-72032013000600004
PURPOSE: To evaluate the level of stress in men and women seeking treatment for infertility and to identify the associated variables. METHODS: A cross-sectional study with 101 men and 101 women consulting for the first time at the Human Reproduction Unit. Participants completed the Brazilian version of the Fertility Problem Inventory (FPI) based on four domains: "social relationships", "life without children"; "marital relationship/sexual" and "maternity/paternity" and a structured questionnaire with socioeconomic and reproductive variables. Bivariate analysis was performed using the Chi-square and Fisher exact tests, considering p<0.05. Afterwards the multivariate correspondence analysis was done with variables with p<0.20. RESULTS: Overall, the participants presented a high level of stress in all domains, except in the "life without children" domain. Multivariate analysis of correspondence showed that variables associated with a high level of stress in the "social relationships" domains were: to be a woman, to have the infertility problem, and to consider the quality of the marital relationship to be regular. In the "life without children" domain the variables that approached the high stress were: to be woman, age between 18 and 24 years, and to have the infertility problem. To be a man, to consider adoption, parents/in-laws and other people knowing about the difficulty to become pregnant, and to consider the quality of the marital relationship to be excellent were the variables associated with high level of stress in "marital/sexual relationship" domain. For "maternity/paternity" domain the variables associated were to be women, consider marital relationship quality regular, age between 25 and 35 years, be evangelical or protestant were the variables associated with a high level of stress. CONCLUSION:Men and women seeking treatment for infertility present a high level of stress and it can be suggested that psychosocial support is important and should be different for men and women.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(6):262-267
DOI 10.1590/S0100-72032013000600005
PURPOSE: To correlate preoperative serum cancer antigen 125 (Ca-125) levels and laparoscopic findings in women with pelvic pain symptoms suggestive of endometriosis. METHODS: A retrospective study was conducted including all women with pelvic pain symptoms suspected for endometriosis operated by laparoscopy from January 2010 to March 2013. Patients were divided into 2 groups according to preoperative Ca-125 level (<35 U/mL and >35 U/mL). Subsequently, patients with ovarian endometriomas were excluded and a further analysis was conducted again according to the preoperative Ca-125 level. The following parameters were compared between groups: presence of ovarian endometrioma, presence and number of deep infiltrating endometriosis (DIE) lesions and American Society for Reproductive Medicine score. The statistical analysis was performed with Statistica version 8.0, using the Fisher exact test, Student's t-test and Mann-Whitney test, when needed. A p value of <0.05 was considered to be statistically significant. RESULTS: During the study period, a total of 350 women were submitted to laparoscopic treatment of endometriosis. One hundred thirty patients (37.1%) had Ca-125>35 U/mL and 220 (62.9%) had Ca-12<35 U/mL. The presence of ovarian endometriomas (47.7 versus 15.9%), DIE lesions (99.6 versus 78.6%) and intestinal DIE lesions (60 versus 30.9%) was more frequent, and the AFSr score was higher (34 versus 6) in the former group. In the second analysis, excluding the patients with ovarian endometriomas (>35 U/mL=68 patients and <35 U/mL=185 patients), similar results were obtained. The presence of DIE lesions (91.2 versus 76.2%), intestinal DIE lesions (63.2 versus 25.4%), bladder DIE lesions (20.6 versus 4.8%) and ureteral DIE lesions (7.3 versus 1.6%) was more frequent, and the AFSr score was higher (10 versus 6) in the Ca-125 >35 U/mL group. CONCLUSIONS: Investigation for DIE is mandatory in women with pelvic pain symptoms suggestive of endometriosis with a preoperative Ca-125 level >35 U/mL, especially when an ovarian endometrioma is not present.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(6):268-273
DOI 10.1590/S0100-72032013000600006
PURPOSE: To describe the anthropometric and pregnancy characteristics of women with HIV/AIDS, assisted by the Brazilian National Health System and the birth weight of their newborns. METHODS: The participants were women assisted at public STD/AIDS clinics of the Municipal Health system of São Paulo. The anthropometric characteristics were evaluated by trained nutritionists and other information was obtained from the medical records. For comparison of the survey data to those of the general population, secondary maternal and pregnancy data were obtained from live birth certificates through the Live Birth Information System. Continuous variables were summarized as mean and standard deviation or as the 25th, 50th and 75th percentiles and minimum and maximum values. The other variables are presented as percentages. Means were compared by the Student's t-test or Kruskal-Wallis test depending on the fulfillment of assumptions, with the decision based on the p value. RESULTS: We found the presence of inadequate maternal nutrition according to triceps skinfold (60.9%). The BMI/gestational age showed the presence of underweight (18.5%) and overweight or obesity (40%). There was no association between disease status (HIV or AIDS) and weight, height, and lean or fat mass. Mean newborn birth weight was lower than the value for the general population without infection or disease. The results of this study indicate the need to develop adapted curves to allow a more accurate nutritional assessment of this population group.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(6):274-280
DOI 10.1590/S0100-72032013000600007
PURPOSE: To analyze the perinatal and pediatric outcome of fetuses that showed nuchal translucency (NT) above the 95th percentile (P95) and a normal karyotype in order to obtain data allowing better maternal prenatal counseling. METHODS: fetuses from a tertiary obstetric service with an NT above P95 and a normal karyotype were analyzed between 2005 and 2011. We analyzed gestational ultrasound follow-up, fetal and postnatal echocardiography (ECHO), weight, length and Apgar score at birth, and neuropsychomotor development by the Ages and Stages Questionnaire (ASQ) up to July 2012. RESULTS: During this period, there were 116 cases of nuchal translucency above the 95th percentile, and the fetal karyotype was determined in 79 of them (68%). Forty-three analyses were normal (54.4%) and 36 were altered (45.6%). Among the fetuses with a normal karyotype, one was miscarried at 15 weeks of gestation with Cantrel pentalogy and one died at 24 weeks with several structural abnormalities. There was one neonatal death of unknown cause and two cases of intraventricular communication (IVC) detected by fetal ECHO. Postnatal echocardiography revealed the persistence of IVC in one case and one case of atrial septal defect (ASD) and patent ductus arteriosus (PDA). Of the 40 surviving children, only 1 showed delayed speech development and another presented autism. The remaining cases resulted in normal neurodevelopment. CONCLUSION: During the monitoring of fetuses with increased NT and a normal karyotype, parents can be best advised that when a 2nd trimester morphological-echocardiography ultrasound study is normal, the probability of the child being born alive and well is high (93.5%).
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(6):281-285
DOI 10.1590/S0100-72032013000600008
PURPOSE: It was to describe and compare the preference of nulliparous and primiparous women for a particular mode of delivery and to determine whether the previous experience of childbirth influences the delivery process. METHODS: We conducted a prospective cross-sectional study. One-hundred interviews were held with 56 nulliparous and 44 primiparous women using previously prepared questionnaires. The quantitative and categorical data were evaluated by the chi-square or Fisher's Exact Test. RESULTS: 60.7% of nulliparous women and 70.5% of primiparous women reported to prefer vaginal delivery. When analyzing the answers about receiving sufficient information about the type of delivery, the presence or absence of influence on the choice of route of delivery and the preferred route of delivery by the partner, there were no statistically significant differences between the two groups. The level of significance used for the tests was 0.05. CONCLUSIONS: This study permitted us to conclude that the previous experience of delivery does not influence the expectation of the delivery process or the choice for a specific mode of delivery. When choosing the route of delivery, women seek to ensure the health of mother and neonate, as well as to avoid the process of pain and suffering.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(5):199-204
DOI 10.1590/S0100-72032013000500002
PURPOSE: To determine the prevalence and associated factors of the hospitalization of pregnant women for treatment of urinary tract infection and the repercussions on the health of the newborn, and the absence of a urine exam during the prenatal period. METHODS: A cross-sectional design, where were eligible all mothers of newborns with births occurring between January 1st and December 31, 2010 in Rio Grande (RS). Mothers were interviewed in the two maternity hospitals in the city. Information was collected regarding hospitalization for urinary tract infection, the prenatal assistance and sociodemographic conditions. Statistical analyses were performed by levels and controlled for confounding using Poisson regression. RESULTS: Of the 2,288 women eligible for the study, 2.9% were hospitalized for treatment of urinary tract infection and was higher, after adjustment, in woman with lowest economic status (3.1% the lowest and 2.1% the highest), younger (4.0% in adolescents and 1.8% in those over 30 years), had less education (3.1% had seven years or less of studying and 1.2% had 12 years or more) and did not live with a partner (4.3% living without partner and 2.6% living with partner). Pathologies of the newborn associated with hospitalization, were preterm birth (4.1% in pre-term and 2.7% in those at term) and low birth weight (6.4% in low and 2.6% in those in normal). Of the women who underwent prenatal care, 23.6% had not done the urine test as recommended and, after adjustment, and the risk for not done the test was higher among those with lower socioeconomic status (34.4% in lower and 14.4% in the highest level), less educated (32.3% with seven years or less of studying and 11.0% with 12 years or more) and not living with a partner (32.7% living without partner and 22.0% living with partner). CONCLUSIONS: The high rate of hospitalization reflects the lack of effectiveness of screening for urinary tract infection during pregnancy. The socioeconomic profile of women who required hospitalization and who did not undergo adequate screening of urinary tract infection in prenatal care, demonstrate the need of more careful attention to pregnant women with the features found.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(5):205-209
DOI 10.1590/S0100-72032013000500003
PURPOSE: To investigate the impact of pregnancy on female sexual function. METHODS: An analytical, cross-sectional study was conducted on 181 non-pregnant and 177 pregnant women aged 18 to 45 years. The study included premenopausal, sexually active women with a steady partner and excluded those taking antidepressants or with a diagnosis of depression. Eleven of these women (6.2%) were in the first trimester, 50 (28.2%), in the second trimester and 116 (65.5%), in the third trimester of pregnancy. The evaluation consisted of an interview in which the Female Sexual Function Index (FSFI) was applied. The data were analyzed using the Statistical Package for the Social Sciences (SPSS) software, version 16.0. The nonparametric Mann-Whitney test was used to compare the mean FSFI values of pregnant and non-pregnant women. RESULTS: Sexual dysfunction was 40.4% among pregnant women and 23.3% among non-pregnant women, with a significant difference between the scores of the studied groups (p=0.01). The difference in the mean global FSFI values between the groups was also significant (p<0.0001). There were significant differences between pregnant and non-pregnant women regarding desire (p<0.0001), excitation (p=0.003), lubrication (p=0.02), orgasm (p=0.005) and satisfaction (p=0.03). The same was not observed regarding pain. CONCLUSION: We conclude that pregnancy negatively influences female sexual function, particularly the desire and excitement domains, revealing the importance of addressing the issue by professionals dealing with pregnant women.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(5):210-214
DOI 10.1590/S0100-72032013000500004
PURPOSE: To determine the relationship between the level of physical activity and the incidence of premenstrual syndrome. METHODS: A cross-sectional design was conducted on 71 apparently healthy university students (24.4±4.8 yrs; 61.5±8.7 kg; 1.63±0.06 m). The level of physical activity was determined with a questionnaire and the presence of premenstrual syndrome was verified based on daily symptoms self-reported in a diary during two consecutive menstrual cycles. 17 premenstrual symptoms are considered in the diary, which should be scored on a 5-point scale (0-4) according to their occurrence, so that a score can be calculated in each cycle. The occurrence of premenstrual syndrome was considered if three or more symptoms were reported up to six days before menstruation (premenstrual period) and were absent up to six days after menstruation (postmenstrual period). RESULTS: The Spearman correlation coefficient showed a significant and negative relationship between the level of physical activity and premenstrual syndrome score (r=-0.506; 95%CI -0.335 to -0.678; p<0.001). When the participants were divided into a group with a positive diagnosis of premenstrual syndrome (n=31) and a healthy group (n=40), the Mann-Whitney test showed higher habitual physical activity in the healthy group than in the premenstrual syndrome group (7.96±1.17 and 6.63±1.20, respectively) (p<0.001). CONCLUSIONS: There is a negative relationship between the level of physical activity and the incidence of premenstrual syndrome, with women with a positive diagnosis of premenstrual syndrome having a lower level of physical activity than healthy women.