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Artigos Originais
Precocious and late pregnancy in adolescents: is there a difference comparing the obstetric risks?
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):446-452
12-05-2006
Summary
Artigos OriginaisPrecocious and late pregnancy in adolescents: is there a difference comparing the obstetric risks?
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):446-452
12-05-2006DOI 10.1590/S0100-72032006000800002
Views154See morePURPOSE: to describe the obstetric outcomes in pregnant adolescents at a tertiary hospital and to compare the maternal and labor outcomes between precocious and late adolescents. METHODS: in a transversal analytical study, 2058 cases were evaluated, considering 322 (15.65%) from the precocious group and 1736 (84.35%) from the late group that delivered at the "Maternidade Escola Assis Chateaubriand/UFC" from January 1, 2000 to December 31, 2000. The clinical complications in the prenatal period, kind of delivery, indications for cesarean section, birth gestational age at birth, birth weight, comparison of birth weight and gestational age, Apgar score at the first and fifth minute, presence of malformations, and neonatal death were analyzed. The exact Fisher and the chi2 tests were used to compare both groups. The prevalence ratio was calculated. RESULTS: from of total of deliveries, 25.95% belonged to adolescents. The average age was 17.19 years. Prenatal visits were made by 88% of the patients, but 60% had an insufficient number of visits. The most frequent clinical situations were preeclampsia (14.72%), anemia (12.97%) and urinary tract infections (6.37%), with no statistical difference between the groups. Thirty-one and three percent of the births were by cesarean section, preeclampsia being the main indication in the two age groups (25 and 23%, respectively). The frequency of an Apgar score less than 7 at the first minute was 19,9% in the precocious adolescent group and 14,2% in the late adolescent group (x²=6,96, p=0.008). There was no statistical difference regarding prematurity rate (20.2 vs 16.1%), low-birth weight infants (12.4 vs 10.4%), low Apgar score at the fifth minute (5.3 vs 3.3%), congenital malformations (3.1 vs 2.7%), and neonatal death (5.3 vs 3.3%). CONCLUSIONS: the precocious and late pregnant adolescents presented similar pregnancy evolution and obstetric outcomes, except for the differences of the first minute Apgar scores.
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Artigos Originais
Fetal heart rate and umbilical artery Dopplervelocimetry between the 18th and 20th weeks of gestation in pregnancies complicated by pregestational diabetes mellitus
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):453-459
12-05-2006
Summary
Artigos OriginaisFetal heart rate and umbilical artery Dopplervelocimetry between the 18th and 20th weeks of gestation in pregnancies complicated by pregestational diabetes mellitus
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):453-459
12-05-2006DOI 10.1590/S0100-72032006000800003
Views74PURPOSE: to analyze the fetal heart rate (FHR) and umbilical artery Dopplervelocimetry between 18th and 20th weeks of gestation in pregnant women complicated by pregestational diabetes mellitus. METHODS: twenty-eight pregnancies with pregestational diabetes and 27 normal pregnant women were analyzed prospectively, in a cross-sectional and case-control study. The inclusion criteria were the following: singleton pregnancy between 18 and 29 weeks, no other associated maternal diseases and no fetal abnormality. Ultrasonography was performed and FHR was calculated by the interval between the beginnings of two consecutive cardiac cycles, in the three umbilical artery Doppler sonograms, obtained in the umbilical cord near to the placental insertion, using color Doppler. Five consecutive FHR cycles from each sonogram were measured, to analyze mean FHR and its variation. The following Doppler indices were studied: systolic/diastolic ratio, pulsatility index (PI) and resistance index (RI). Student's t test and Mann-Whitney Utest were applied to comparative study. p values were considered significant when p<0.05. Results: no significant difference was observed in mean FHR between the studied groups (diabetic group: 149.2 bpm, control group: 147.2 bpm; p = 0.12). FHR variation revealed similar results between the groups (diabetic group: 5.3 bpm; control group: 5.3 bpm; p=0.50). No significant difference was found in the Doppler indices S/D (p=0.79), PI (p=0.25) and RI (p=0.71) between the groups. CONCLUSIONS: the absence of differences in FHR characteristics between the 18th and 20th gestational weeks indicates similar neurological maturation of FHR regulatory systems in this period, between fetuses of diabetic mothers and controls. Abnormalities in the uteroplacental resistance were not identified in the studied period, in pregnancies complicated by pregestational diabetes.
Key-words Diabetes mellitusDopplerfetalHeart rateLaser-doppler flowmetryUltrasonographyUmbilical arteriesSee more -
Artigos Originais
Lamellar body count versus the shake test in the assessment of fetal lung maturity in diabetics
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):460-466
12-05-2006
Summary
Artigos OriginaisLamellar body count versus the shake test in the assessment of fetal lung maturity in diabetics
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):460-466
12-05-2006DOI 10.1590/S0100-72032006000800004
Views143PURPOSE: to assess the performance of lamellar body count compared to the shake (Clements) test in the prediction of fetal lung maturity in diabetics. METHODS: prospective study of 62 patients who underwent amniocentesis between the 26th and 39th week of pregnancy. Immediately after collection, the amniotic fluid sample was submitted to the shake test and lamellar body count. Deliveries occurred within three days of amniocentesis. Immature test results (absence of a complete bubble ring in the third tube for the shake test and less than 50,000 lamellar bodies) were confronted with the occurrence of pulmonary immaturity in the neonate (respiratory distress syndrome). The performance of both tests was compared using the chi2 test and p<0.05 was considered to be significant. RESULTS: seven infants had respiratory distress syndrome (11.3%). The lamellar body count and shake test were similar regarding sensitivity (100 vs 71.4%, respectively) and negative predictive value (100 vs 93.5%). Lamellar body count was superior as regards specificity (87.3 vs 52.7%, p=0.0001), positive predictive value (50 vs 16.1%, p=0.017), and accuracy (88.7 vs 54.8%, p<0.001). CONCLUSIONS: lamellar body count is a simple and accurate method of assessing fetal lung maturity. It performs slightly better than the shake test in terms of specificity, positive predictive value and accuracy, with the advantage of not requiring manipulation or reagents. Similar to the shake test, lamellar body count has a high-negative predictive value: mature results (50,000 or more) indicate thar the infant will not have hyaline membrane.
Key-words Amniotic fluidDiabetes mellitusFetal organ maturityLungNewbornPregnancy in diabeticsRespiratory distress syndromeSee more -
Artigos Originais
Human T-cell lymphotropic virus type I seroprevalence among pregnant women in Goiânia, GO, Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):467-472
12-05-2006
Summary
Artigos OriginaisHuman T-cell lymphotropic virus type I seroprevalence among pregnant women in Goiânia, GO, Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):467-472
12-05-2006DOI 10.1590/S0100-72032006000800005
Views78PURPOSE: to assess human T-cell lymphotropic virus type I (HTLV-I) seroprevalence among pregnant women attended at Public Health Units in Goiânia-Goiás and some epidemiologic characteristics of the studied group. METHODS: from September/2003 to December/2004, 15,485 pregnant women were submitted to enzyme-linked immunoabsorbent assays (ELISA), to screen HTLV-I, using filter paper - dried blood in, and to confirm the infection, polymerase chain reaction (PCR) of whole blood was performed. The epidemiologic factors evaluated were: average age, age of 30 years and above, schooling less than nine years, marital status and number of pregnancies. The factors average age, age of 30 years and above, and schooling less than nine years were compared between the infected and non-infected pregnant group. Statistical analysis used Fisher's exact test and Student's t test. RESULTS: the found prevalence was 0.1%. The average age among the infected pregnant group was 26.4 years, 43.7% of them being 30 years old and above, and 62.5% with schooling less than nine years. The non-infected group showed an average age of 24.4 years, 15.4% of them being ³ 30 years old and above, and only 41.5% with schooling less than nine years. Significant statistical difference was noticed only regarding age of 30 years and above and schooling less than nine years. CONCLUSION: the study shows that HTLV-I seroprevalence among pregnant women in Goiânia during the studied period was 0.1%. It occurred more among pregnant women who were 30 years old and above and those with schooling of less than nine years.
Key-words Disease transmissionHuman T-lymphotropic virus 1infectiousPregnancy complicationsPregnant womenSeroepidemiologic studiesverticalSee more -
Artigos Originais
Application of a levonorgestrel-releasing intrauterine device prior to in vitro fertilization cycles in women with adenomyosis
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):473-478
12-05-2006
Summary
Artigos OriginaisApplication of a levonorgestrel-releasing intrauterine device prior to in vitro fertilization cycles in women with adenomyosis
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(8):473-478
12-05-2006DOI 10.1590/S0100-72032006000800006
Views125See morePURPOSE: to verify the effects of intrauterine levonorgestrel device (IUD) in women with adenomyosis, with implantation failure in previous in vitro fertilization (IVF) cycles. METHODS: eighty infertile women with ages up to 38 years, who had adenomyosis diagnosed by ultrasonography and MRI were selected. All the women presented antecedents of one or more tormer IVF attempts without success due to implantation failure. The women were subdivided into IUD Group, composed of 40 women with an IUD that released 20 µg of levonorgestrel/day during six months, preceding a new IVF cycle, and IVF Group, also composed of 40 women, who were directly submitted to a new IVF cycle without previous adenomyosis treatment. In the IUD Group the uterine volume, thickness and hypersignal foci of the junctional zone were assessed before and after treatment, as well as the pregnancy rates in the new IVF cycle, compared to the data obtained with the IVF Group. Statistical analyses were performed adopting the significance level of 5% (p<0,05), using the Mann-Whitney and Sudent's t tests. RESULTS: after treatment, there was a reduction of 77.7% in the cases of focal adenomyosis, in addition to a significant reduction of the uterine volume and of the mean thickness of the junctional zone from 128.8 to 93.6 ml and from 12.3 to 11.3 mm, respectively. In the IUD Group, pregnancy rate reached 30%, which was higher than, but not significantly different from that of the IVF group, which was 17.5%. CONCLUSION: the use of an IUD with levonorgestrel may be administered prior to IVF cycles in patients with adenomyosis who suffered previous implantation failure.
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Artigos Originais
Maternal factors and perinatal results in placental abruption: a comparative study of two periods
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):324-330
10-20-2006
Summary
Artigos OriginaisMaternal factors and perinatal results in placental abruption: a comparative study of two periods
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):324-330
10-20-2006DOI 10.1590/S0100-72032006000600002
Views109See morePURPOSE: to compare the maternal factors, clinical aspects and perinatal results in placental abruption during two periods. METHODS: retrospective analysis of placental abruption cases that occurred from January 1, 1994 through December 31, 1997 (period 94-97), and from April 4, 2001 through March 3, 2005 (period 01-05), in singleton delivery with birthweight higher than 500 g and after 20 weeks of gestation. The following factors were analyzed: maternal age, previous obstetric history, prenatal care, premature rupture of membranes, obstetric and/or clinical intercurrent events, vaginal bleeding, uterine tonus, fetal anomaly, mode of delivery, hemoamnion and maternal complication (hysterectomy, uterine atony, disseminated intravascular coagulation, acute renal failure, and maternal death), and the perinatal results. RESULTS: the rate of placental abruption was 0.78% (60 cases) in the period 94-97 (n=7692 deliveries), and 0.59% (51 cases) in the period 01-05 (n=8644 deliveries), without significant difference. A significant difference was observed between the periods 94-97 and 01-05 regarding mean number of previous gestations (3.5±2.4 and 2.6±1.8, p=0.04), patients without prenatal care (13.3 and 2.0%, p=0.03) and maternal intercurrences (38.3 and 64.7%, p=0.01). No significant difference was observed related to vaginal bleeding, tonus abnormalities and perinatal results, between the periods, but a higher proportion of hemoamnion in 94-97 was found when compared to 01-05 (28.3 and 11.8%, p=0.03). CONCLUSIONS: in spite of obstetrical advances, maternal complications and perinatal results were similar in the analyzed periods. The severity and the unexpected results emphasize the importance of prevention and adequate control of associated factors, when this pathology is approached.
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Artigos Originais
Low educational level as a limiting factor in the fight against anemia in pregnant women
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):331-339
10-20-2006
Summary
Artigos OriginaisLow educational level as a limiting factor in the fight against anemia in pregnant women
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):331-339
10-20-2006DOI 10.1590/S0100-72032006000600003
Views88PURPOSE: to evaluate the impact of supplementary ferrous sulfate and dietary counseling on hemoglobin levels in pregnant women. METHODS: a total of 197 pregnant women were evaluated during antenatal care at a health center. The treatment group consisted of 105 women who were prescribed 60 mg dietary iron per day, received dietary counseling and had hemoglobin measured by a portable photometer between the 14th and 20th week of pregnancy. The treatment group was reevaluated according to hemoglobin levels and food intake by a semiquantitative food frequency questionnaire after the 34th week of pregnancy. The control group consisted of 92 women in a cross-sectional study, at no less than 34 weeks of pregnancy. Hemoglobin was analyzed by a portable photometer and anemia was defined concentrations of less than 11 g/dL. All pregnant women had their weight and height measured. Hierarchical logistic regression model was developed for the multivariate analysis. RESULTS: prevalence of anemia at the end of the third trimester was 31.6% in the treatment group and 26.1% in the control group (p=0.43). Use of the prescribed supplement was reported by 65% of women in the treatment group, of which 67.7% interrupted the treatment at some point. Principal reasons for interrupting treatment were forgetting (43.2%) and nausea or vomiting (27.2%). Risk of anemia in the third trimester was three times higher in women with less than 8 years of schooling. CONCLUSIONS: use of ferrous sulfate was not shown to be associated with lower prevalence of anemia. The results suggest that structural changes in socioeconomic conditions are needed in order to alter the current situation regarding iron deficiency anemia.
Key-words AnemiaEducational statusFerrous sulfateHemoglobinsPregnancySupplementary feedingTreatment outcomeSee more -
Artigos Originais
Effects of maternal smoking on placental ultrasound and uterine-placental Doppler
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):340-344
10-20-2006
Summary
Artigos OriginaisEffects of maternal smoking on placental ultrasound and uterine-placental Doppler
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):340-344
10-20-2006DOI 10.1590/S0100-72032006000600004
Views63See morePURPOSE: the study the effects of maternal cigarette smoking during pregnancy on placental maturation (calcifications) and the placental-uterine circulation, evaluated through umbilical and uterine Doppler. METHODS: prospective cohort study involving 244 pregnant women, 210 of them non-smokers and 34 smokers. Participants were submitted to four serial sonograms. The first was performed up to the 16th week of pregnancy to determine gestational age, and the other three at 28, 32 and 36 weeks for fetal biometry, evaluation of placental texture and Doppler studies of the uterine and umbilical arteries. Premature placental calcification was defined as grade III before 36 weeks. The chi2 and Fisher exact tests were used to compare placental grading, and the Mann-Whitney test to evaluate the resistance index of uterine and umbilical arteries. RESULTS: the frequency of grade III placenta and the resistance of the uterine arteries did not differ significantly between smokers and non-smokers, at all gestational ages. Umbilical artery Doppler was significantly higher in smokers than in non-smokers at 32 weeks. CONCLUSIONS: no association was found between cigarette smoking and premature placental calcification. Smoking was associated with increased umbilical artery resistance at 32 weeks.