Articles - Revista Brasileira de Ginecologia e Obstetrícia

Editorial
Ética em pesquisa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(9):494-494
04-09-1998

Views43

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Summary
Editorial
Ética em pesquisa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(9):494-494
04-09-1998
DOI 10.1590/S0100-72031998000900001
Views43
Ética em Pesquisa […]
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Resumos de Teses
Estudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina
- Moisés Mendonça Neto
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):424-424
04-09-1998

Views37

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Resumos de Teses
Estudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):424-424
04-09-1998
DOI 10.1590/S0100-72031998000700011
Moisés Mendonça Neto
Views37
Estudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina […]
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Resumos de Teses
Estudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses
- Cláudia de Carvalho Ramos Bortoletto
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-423
04-09-1998

Views33

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Resumos de Teses
Estudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-423
04-09-1998
DOI 10.1590/S0100-72031998000700009
Cláudia de Carvalho Ramos Bortoletto
Views33
Estudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses[…]
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Resumos de Teses
Sangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada – Recife (PE)
- Welkovic Stefan
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-424
04-09-1998

Views37

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Summary
Resumos de Teses
Sangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada – Recife (PE)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-424
04-09-1998
DOI 10.1590/S0100-72031998000700010
Welkovic Stefan
Views37
Sangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada Recife (PE) […]
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Relato de Caso
Complete Mole in Twin Pregnancy: a Case Report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):415-419
04-09-1998

Views72

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Summary
Relato de Caso
Complete Mole in Twin Pregnancy: a Case Report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):415-419
04-09-1998
DOI 10.1590/S0100-72031998000700008
Izildinha Maestá,
Iracema M.P. Calderon,
Marilza V.C. Rudge,
Magaly M. Sales,
Fabiano P. Saggioro,
José Carlos Peraçoli
Views72
Twin pregnancy in which a normal fetus and a complete mole develop at the same time is a rare event. Clinical complications and malignancy are frequent in this type of disease.This report is about a case of a late diagnosis due to the presence of the fetus. The diagnosis was made when the pregnancy was interrupted and then confirmed by histopathological study and flow cytometry. The pregnancy was terminated transpelvically due to massive uterine hemorrhage. The post-molar follow-up showed the persistence of high levels of bhCG. The patient’s complete recovery was achieved after the administration of methotrexate. The diagnosis, natural history, and procedures for this rare disease are discussed in view of this case.

Key-words Chemotherapy Complete hydatidiform mole Gestational trophoblastic disease Hemorrhage Pregnancy complications Twin pregnancy Ultrasonography
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Relato de Caso
Clear Cell Adenocarcinoma of the Endocervix in a 7-year-old Child
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):411-414
04-09-1998

Views84

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Summary
Relato de Caso
Clear Cell Adenocarcinoma of the Endocervix in a 7-year-old Child
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):411-414
04-09-1998
DOI 10.1590/S0100-72031998000700007
Marta Francis Benevides Rehme,
Mauro Fernando Kürten Ihlenfeld,
Ana Carolina Silva Chuery
Views84
Clear cell adenocarcinoma of the vagina and cervix is a rare disease associated commonly with the use of diethylstilbestrol (DES) during pregnancy. The most commom complaint is irregular vaginal bleeding, which could be confused with vaginitis in children and abnormalities in the hypothalamic-pituitary axis in adolescents. We report a case of clear cell adenocarcinoma of the endocervix in a 7-year-old child who was attended at the Children and Adolescent Gynecology Sector, and we call attention to the diagnosis of genital cancer which, in spite of its rarity at this age, must be considered in children with genital bleeding.

Key-words Carcinoma Childhood and adolescence Uterine cervix Vaginal cancer
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Equipamentos e Métodos
Endometrial Resection by Video-Hysteroscopy: experience in a Teaching Hospital
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):405-410
04-09-1998

Views76

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Summary
Equipamentos e Métodos
Endometrial Resection by Video-Hysteroscopy: experience in a Teaching Hospital
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):405-410
04-09-1998
DOI 10.1590/S0100-72031998000700006
Caio Parente Barbosa,
Marcelo Ettruri Santos,
Ana Cristina Napolitano,
Paula Harue Tamanaka,
Emerson Barchi Cordts
Views76
Objective: to demonstrate the effectiveness of video-hysteroscopic endometrial resection in the treatment of abnormal uterine bleeding. Patients and method: The authors studied 60 records of patients with abnormal uterine bleeding who did not respond to clinical treatment. Results: eighty-eight percent of the patients had adequate response to the treatment (53% oligomenorrhea and 35% amenorrhea). The complication rate was 8.3% (5 uterine perforations). Conclusion: video-hysteroscopic endometrial resection is an effective technique to treat abnormal uterine bleeding which failed to respond to clinical management. The intra and postoperative complication rates are low.

Key-words Endometrial hyperplanaresection Hysteroscopy
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Trabalhos Originais
Maternal Mortality in São Paulo City in 1996
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):395-403
04-09-1998

Views100

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Summary
Trabalhos Originais
Maternal Mortality in São Paulo City in 1996
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):395-403
04-09-1998
DOI 10.1590/S0100-72031998000700005
Luis Carlos Pazero,
Paulo Afonso Ferrigno Marcus,
Carlos Eduardo Pereira Vega,
Krikor Boyaciyan,
Sônia Antonini Barbosa
Views100
Purpose: to establish a list of diseases promoting maternal death according to frequency. Methods: In 1996, 65,406 deaths were recorded in the City of São Paulo, 26,778 of which were of women. Of these, 4591 were within the 10-49 year age bracket. We analyzed the latter group, regarding at the field “Cause of Death” in the Death Certificate, trying to establish some correlation between the described pathology, and the pregnancy-puerperium cycle. We separated for a further study 293 Death Certificates, from which we selected, after hospital survey and/or home visits, a total of 119 positive cases for maternal death. The positive cases for maternal death were then tabulated, grouped and analyzed according to age and pathology, using the great medical care groups. Results: as regards the 119 positive cases for maternal death, we did not find any reference to the pregnancy-puerperium state in 53 of them (that is, 40.54% subnotifying). The cases were grouped according to pathology, where we found a predominance of eclampsia/pre-eclampsia cases (18.02%), followed by cases resulting from hemorrhagic complications in the third quarter and puerperium (12.61%), abortion complications (12.61%), puerperal infection (9.91%) and cardiopathies (9.91%). Conclusions: for the first time, we are publishing the Late Maternal Mortality Coefficient for the City of São Paulo, which was 51.33/100,000 born alive. However, we used for the official publication the Maternal Mortality Coefficient for death within up to 42 days of puerperium, which was, 48.03/100,000 born alive for the city of São Paulo. We should bear in mind that no correction factor should be applied to these figures since we have made an active search of cases.

Key-words Cardiopathy in pregnancy Eclampsia Hemorrhagic complications in pregnancy Maternal mortality Maternal mortality coefficient Pregnancy complications
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Original Article
Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo9
00-00-2024

Views400

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Summary
Original Article
Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo9
00-00-2024
DOI 10.61622/rbgo/2024AO09
Thaís Loureiro Felipe ,
Patrícia Paula da Fonseca Grili ,
Camila Vilarinho Vidigal ,
Ben-Hur Albergaria ,
Geise Ferreira da Cruz ,
José Luiz Marques-Rocha ,
Valdete Regina Guandalini
Views400
Abstract

Objective:

To analyze the amount of muscle and the presence of sarcopenia in postmenopausal women using different methods, verifying the agreement between them as to skeletal muscle mass (SMM).

Methods:

This cross-sectional observational study was conducted with postmenopausal women aged ≥ 50 years. SMM was obtained from a predictive equation, Bioelectrical Impedance (BIA), and Dual Energy X-Ray Absorptiometry (DXA). The skeletal muscle mass index (SMI) and the appendicular skeletal muscle mass index (ASMI) were calculated. The cut-off point of SMI was determined for the population itself. The agreement between the SMI obtained using the different methods was verified. Sarcopenia was diagnosed according to the criteria proposed by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2). The significance level adopted for all tests was 5.0%.

Results:

A total of 112 women were evaluated, with an average age of 66.1 ± 5.65 years. Among them, 51.8% were sufficiently active and 43.8% were overweight and obese. The SMI cut-offs were 6.46 kg/m² for the predictive equation and 7.66 kg/m² for BIA, with high sensitivity and specificity. There was an excellent agreement in the identification of SMM by the predictive equation (0.89 [0.824-0.917], p < 0.001) and BIA (0.92 [0.883-0.945], p < 0.001), in reference to DXA. The prevalence of sarcopenia was 0.9%, 1.8%, and 2.7% according to BIA, DXA, and the predictive equation, respectively.

Conclusion:

The predictive equation showed the expected agreement in estimating skeletal muscle mass in postmenopausal women, offering a viable and accurate alternative.

Key-words Anthropometry Bioelectrical impedance Body composition Muscle mass Obesity Overweight Postmenopause sarcopenia Skeletal Muscle
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Original Article/Infertility
The Role of Thyroid Hormones, Vitamins, and Microelements in Female Infertility
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(11):683-688
12-05-2023

Views394

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Summary
Original Article/Infertility
The Role of Thyroid Hormones, Vitamins, and Microelements in Female Infertility
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(11):683-688
12-05-2023
DOI 10.1055/s-0043-1772478
Aghayeva Sveta ,
Murat Sonmezer ,
Yavuz Emre Şükür ,
Aytaj Jafarzade
Views394
Abstract

Objective

It is well known that female infertility is multifactorial. Therefore, we aimed to compare the effects of thyroid dysfunction, vitamin deficiency, and microelement deficiency in fertile and infertile patients.

Materials and Methods

Between May 1st, 2017, and April 1st, 2019, we conducted a retrospective case-control study with of 380 infertile and 346 pregnant patients (who normally fertile and able to conceive spontaneously). The fertile patients were selected among those who got pregnant spontaneously without treatment, had a term birth, and did not have systemic or obstetric diseases. The levels of thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), anti-thyroid peroxidase (anti-TPO), vitamin D, vitamin B12, folic acid, ferritin, and zinc of both groups were compared.

Results

There was no difference between patients in the infertile and pregnant groups in terms of low normal and high serum T3 and T4 levels (p = 0.938; p > 0.05) respectively, nor in terms of normal and high anti-TPO levels (p = 0.182; p > 0.05) respectively. There was no significant difference regarding patients with low, insufficient, and sufficient vitamin D levels in the infertile and pregnant groups (p = 0.160; p >0.05) respectively. The levels of folic acid, ferritin, and zinc of the infertile group were significantly lower than those of the pregnant group.

Conclusion

The serum levels of folic acid, ferritin, and zinc in infertile patients presenting to our outpatient clinic were lower than those o the fertile patients.

Key-words ferritin Folic acid Infertility thyroid hormones Vitamin B12 vitamin D zinc
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Original Article
Sociodemographic and reproductive risk factors associated with metabolic syndrome in a population of Brazilian women from the city of Ribeirão Preto: a cross-sectional study
- Ênio Luis Damaso ,
- Heloisa Bettiol ,
- Viviane Cunha Cardoso ,
- Mariane Nunes de Nadai ,
- Elaine Christine Dantas Moisés ,
- Ricardo Carvalho Cavalli
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo8
00-00-2024

Views393

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Summary
Original Article
Sociodemographic and reproductive risk factors associated with metabolic syndrome in a population of Brazilian women from the city of Ribeirão Preto: a cross-sectional study
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo8
00-00-2024
DOI 10.61622/rbgo/2024AO08
Ênio Luis Damaso ,
Heloisa Bettiol ,
Viviane Cunha Cardoso ,
Mariane Nunes de Nadai ,
Elaine Christine Dantas Moisés ,
Carolina Sales Vieira ,
Ricardo Carvalho Cavalli
Views393
Abstract

Objective:

To identify sociodemographic and reproductive risk factors associated with MetS in women in their fourth decade of life.

Methods:

Cohort study conducted on women born from June 1978 to May 1979 in Ribeirão Preto, Brazil. Sociodemographic, clinical, and obstetric data were collected by interview and clinical evaluation. Univariable and multivariable binomial logistic regression models were constructed to identify the risk factors of metabolic syndrome and the adjusted relative risk (RR) was calculated.

Results:

The cohort included 916 women, and 286 (31.2%) of them have metabolic syndrome. MetS was associated with lack of paid work (RR 1.49; 95% CI 1.14-1.95), marital status of without a partner (RR 1.33; 95% CI 1.03-1.72), low educational level (less than 8 years of schooling [RR 1.72; 95% CI 1.23-2.41], 8 to 12 years of schooling [RR 1.37; 95% CI 1.06-1.76], when compared with more than 12 years of schooling), and teenage pregnancy (RR 2.00; 95% CI 1.45-2.77). There was no association between MetS, and the other covariates studied.

Conclusion:

Metabolic syndrome in a population of women in the fourth decade of life was associated with lack of employment, lack of a partner, low educational level, and teenage pregnancy.

Key-words cohort study metabolic syndrome Obesity Risk factors
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Editorial
RBGO – A journal to support gynecology and obstetrics research in Latin America
- Marcos Felipe Silva de Sá
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgoedt1
00-00-2024

Views393

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Summary
Editorial
RBGO – A journal to support gynecology and obstetrics research in Latin America
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgoedt1
00-00-2024
DOI 10.61622/rbgo/2024EDT01
Marcos Felipe Silva de Sá
Views393
In 2016, the Brazilian Federation of the Gynecology and Obstetrics Associations – FEBRASGO began a major restructuring process of the RBGO – Revista Brasileira de Ginecologia e Obstetrícia with significant changes in its editorial policy. Since that date, after the editorial board was reformulated, the articles began to be published in English with absolute regularity […]
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Original Article
Impact of doula’s continuous support on serotonin release in parturients: a pilot randomized clinical trial
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo27
04-09-2024

Views389

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Impact of doula’s continuous support on serotonin release in parturients: a pilot randomized clinical trial
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo27
04-09-2024
DOI 10.61622/rbgo/2024rbgo27
Eleonora de Deus Vieira de Moraes ,
Mayara Segundo Ribeiro ,
Cíntia Erbert ,
Caio Antonio de Campos Prado ,
Elaine Christine Dantas Moisés
Views389
Abstract

Objective:

To evaluate whether the continuous support provided by doulas influences the endogenous release of serotonin in parturients.

Methods:

This pilot study included 24 primigravidae at term. Of these, 12 women received continuous doula support (Experimental Group), whereas the other 12 received the usual assistance without doula support (Control Group). Blood samples were collected from all the women at the active and expulsion stages of labor and at the fourth period of labor (Greenberg period) for evaluation of their serotonin levels using high-performance liquid chromatography.

Results:

The average serotonin concentrations in the control and experimental groups were respectively 159.33 and 150.02 ng/mL at the active stage, 179.13 and 162.65 ng/mL at the expulsion stage, and 198.94 and 221.21 ng/mL at the Greenberg period. There were no statistically significant differences in serotonin concentrations between the two groups at the active and expulsion stages of labor. By contrast, within the experimental group, a significant increase in serotonin concentration was observed in the Greenberg period compared with the levels in the active and expulsion stages (p < 0.05).

Conclusion:

The novelty of this study relies on the ability to correlate the influence of the continuous support offered by doulas with the release of serotonin in parturients, with the results suggesting that the assistance received during labor can modulate the levels of hormone release in the Greenberg period.

Brazilian Registry of Clinical Trials:

RBR-4zjjm4h

Key-words Doulas Humanized delivery Labor Pregnant women Serotonin
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Original Article
Outcomes after elevation of serratus anterior fascia flap versus serratus muscle flap in direct-to-implant breast reconstruction following mastectomy: a prospective study
- Lilian de Sá Paz Ramos ,
- Jorge Villanova Biazús
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo13
00-00-2024

Views372

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Outcomes after elevation of serratus anterior fascia flap versus serratus muscle flap in direct-to-implant breast reconstruction following mastectomy: a prospective study
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo13
00-00-2024
DOI 10.61622/rbgo/2024AO13
Lilian de Sá Paz Ramos ,
Jorge Villanova Biazús
Views372
Abstract

Objective:

The purpose of this study was to compare postoperative pain between SF flap and serratus anterior muscle (SM) in direct-to-implant breast reconstruction.

Methods:

This is a prospective cohort study that included 53 women diagnosed with breast cancer who underwent mastectomy and one-stage implant-based breast reconstruction from January 2020 to March 2021. Twenty-nine patients (54.7%) had SF elevation, and 24 patients (45.3%) underwent SM elevation. We evaluated patient-reported early postoperative pain on the first day after surgery. Also, it was reported that all surgical complications in the first month and patient reported outcomes (PROs) were measured with the BRECON 23 questionnaire.

Results:

The serratus fascia group used implants with larger volumes, 407.6 ± 98.9 cc (p < 0.01). There was no significant difference between the fascial and muscular groups regarding the postoperative pain score reported by the patients (2 versus 3; p = 0.30). Also, there was no difference between the groups regarding early surgical complications and PROs after breast reconstruction.

Conclusion:

The use of SF seems to cause less morbidity, which makes the technique an alternative to be considered in breast reconstruction. Although there was no statistical difference in postoperative pain scores between the fascia and serratus muscle groups.

Key-words Breast implants Breast neoplasms breast reconstruction Fascia Mastectomy Pain Postoperative period
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Original Article
Screening of Perinatal Depression Using the Edinburgh Postpartum Depression Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(5):452-457
03-04-2022

Views371

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Screening of Perinatal Depression Using the Edinburgh Postpartum Depression Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(5):452-457
03-04-2022
DOI 10.1055/s-0042-1743095
Tenilson Amaral Oliveira ,
Guilherme Guarany Cardoso Magalhães Luzetti ,
Márcia Maria Auxiliadora Rosalém ,
Corintio Mariani Neto
Views371
Abstract

Objective

To detect depression during pregnancy and in the immediate postpartum period using the Edinburgh postpartum depression scale (EPDS).

Methods

Cross sectional study of 315 women, aged between 14 and 44 years, who received perinatal care at the Leonor Mendes de Barros Hospital, in São Paulo, between July 1st, 2019 and October 30th, 2020. The cutoff point suggesting depression was ≥ 12.

Results

The screening indicated 62 (19.7%) patients experiencing depression. Low family income, multiparity, fewer prenatal appointments, antecedents of emotional disorders, dissatisfaction with the pregnancy, poor relationship with the partner, and psychological aggression were all risk factors associated with depression in pregnancy or in the immediate postpartum period. Antecedents of depression and psychology aggression during pregnancy were significant variables for predicting perinatal depression in the multivariate analysis.

Conclusion

There is a significant association between the occurrence of perinatal depression and the aforementioned psychosocial factors. Screening patients with the EPDS during perinatal and postpartum care could facilitate establishing a line of care to improve the wellbeing of mother and infant.

Key-words Depression Postpartum period Pregnancy Prenatal care Risk factors
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Review Article
The Female Athlete Triad/Relative Energy Deficiency in Sports (RED-S)
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):395-402
07-30-2021

Views369

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Review Article
The Female Athlete Triad/Relative Energy Deficiency in Sports (RED-S)
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):395-402
07-30-2021
DOI 10.1055/s-0041-1730289
Alexandra Ruivo Coelho ,
Gonçalo Cardoso ,
Marta Espanhol Brito ,
Inês Neves Gomes ,
Maria João Cascais
Views369
Abstract

In a healthy athlete, the caloric intake is sufficient for sports energy needs and body physiological functions, allowing a balance between energy availability, bone metabolism, andmenstrual cycle.Onthe other hand, an imbalance causedby low energy availability dueto a restrictive diet, eating disorders or long periods of energy expenditure leads to multisystemic deregulation favoring the essential functions of the body. This phenomenon, described as the female athlete triad, occurs in a considerable percentage of high-performance athletes, with harmful consequences for their future. The present review was carried out based on a critical analysis of themost recent publications available and aims to provide a global perception of the topic relative energy deficit in sport (RED-S). The objective is to promote theacquisition ofmore consolidated knowledgeon an undervaluedtheme, enabling the acquisition of preventive strategies, early diagnosis and/or appropriate treatment.

Key-words Amenorrhea bone health female athlete low energy availability menstrual dysfunction
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Review Article
Efficacy of Hormonal and Nonhormonal Approaches to Vaginal Atrophy and Sexual Dysfunctions in Postmenopausal Women: A Systematic Review
- Ayane Cristine Alves Sarmento ,
- Ana Paula Ferreira Costa ,
- Juliana Lírio ,
- José Eleutério Jr ,
- Pedro Vieira Baptista ,
- Ana Katherine Gonçalves
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(10):986-994
01-23-2022

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Review Article
Efficacy of Hormonal and Nonhormonal Approaches to Vaginal Atrophy and Sexual Dysfunctions in Postmenopausal Women: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(10):986-994
01-23-2022
DOI 10.1055/s-0042-1756148
Ayane Cristine Alves Sarmento ,
Ana Paula Ferreira Costa ,
Juliana Lírio ,
José Eleutério Jr ,
Pedro Vieira Baptista ,
Ana Katherine Gonçalves
Views292
Abstract

Objective

To evaluate the efficacy of the hormonal and nonhormonal approaches to symptoms of sexual dysfunction and vaginal atrophy in postmenopausal women.

Data Sources

We conducted a search on the PubMed, Embase, Scopus, Web of Science, SciELO, the Cochrane Central Register of Controlled Trials (CENTRAL), and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases, as well as on clinical trial databases. We analyzed studies published between 1996 and May 30, 2020. No language restrictions were applied.

Selection of Studies

We selected randomized clinical trials that evaluated the treatment of sexual dysfunction in postmenopausal women.

Data Collection

Three authors (ACAS, APFC, and JL) reviewed each article based on its title and abstract. Relevant data were subsequently taken from the full-text article. Any discrepancies during the review were resolved by consensus between all the listed authors.

Data Synthesis

A total of 55 studies were included in the systematic review. The approaches tested to treat sexual dysfunction were as follows: lubricants and moisturizers (18 studies); phytoestrogens (14 studies); dehydroepiandrosterone (DHEA; 8 studies); ospemifene (5 studies); vaginal testosterone (4 studies); pelvic floor muscle exercises (2 studies); oxytocin (2 studies); vaginal CO₂ laser (2 studies); lidocaine (1 study); and vitamin E vaginal suppository (1 study).

Conclusion

We identified literature that lacks coherence in terms of the proposed treatments and selected outcome measures. Despite the great diversity in treatment modalities and outcome measures, the present systematic review can shed light on potential targets for the treatment, which is deemed necessary for sexual dysfunction, assuming that most randomized trials were evaluated with a low risk of bias according to the Cochrane Collaboration risk of bias tool. The present review is registered with the International Prospective Register of Systematic Reviews (PROSPERO; CRD42018100488).

Key-words Dyspareunia Estrogens Menopause orgasm Therapeutics
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Review Article
Placental Findings in Preterm and Term Preeclampsia: An Integrative Review of the Literature
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(7):560-569
10-18-2021

Views206

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Review Article
Placental Findings in Preterm and Term Preeclampsia: An Integrative Review of the Literature
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(7):560-569
10-18-2021
DOI 10.1055/s-0041-1730292
Luciana Pietro ,
José Paulo de Siqueira Guida ,
Guilherme de Moraes Nobrega ,
Arthur Antolini-Tavares ,
Maria Laura Costa
Views206
Abstract

Introduction

Preeclampsia (PE) is a pregnancy complication associated with increased maternal and perinatal morbidity and mortality. The disease presents with recent onset hypertension (after 20 weeks of gestation) and proteinuria, and can progress to multiple organ dysfunction, with worse outcomes among early onset preeclampsia (EOP) cases (<34 weeks). The placenta is considered the root cause of PE; it represents the interface between the mother and the fetus, and acts as a macromembrane between the two circulations, due to its villous and vascular structures. Therefore, in pathological conditions, macroscopic and microscopic evaluation can provide clinically useful information that can confirm diagnosis and enlighten about outcomes and future therapeutic benefit.

Objective

To perform an integrative review of the literature on pathological placental findings associated to preeclampsia (comparing EOP and late onset preeclampsia [LOP]) and its impacts on clinical manifestations.

Results:

Cases of EOP presented worse maternal and perinatal outcomes, and pathophysiological and anatomopathological findings were different between EOP and LOP placentas, with less placental perfusion, greater placental pathological changes with less villous volume (villous hypoplasia), greater amount of trophoblastic debris, syncytial nodules, microcalcification, villous infarcts, decidual arteriolopathy in EOP placentas when compared with LOP placentas. Clinically, the use of low doses of aspirin has been shown to be effective in preventing PE, as well asmagnesium sulfate in preventing seizures in cases of severe features.

Conclusion

The anatomopathological characteristics between EOP and LOP are significantly different, with large morphological changes in cases of EOP, such as

Key-words anatomopathological characteristics maternal mortality and morbidity Placenta preeclampsia early onset preeclampsia late onset
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Case Report
Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations
- Arlley Cleverson Belo da Silva ,
- Jurandir Piassi Passos ,
- Roney Cesar Signorini Filho ,
- Antonio Braga ,
- Rosiane Mattar ,
- Sue Yazaki Sun
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(4):323-328
06-18-2021

Views170

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Case Report
Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(4):323-328
06-18-2021
DOI 10.1055/s-0041-1725054
Arlley Cleverson Belo da Silva ,
Jurandir Piassi Passos ,
Roney Cesar Signorini Filho ,
Antonio Braga ,
Rosiane Mattar ,
Sue Yazaki Sun
Views170
Abstract

Complete hydatidiform mole (CHM) is a rare type of pregnancy, in which 15 to 20% of the cases may develop into gestational trophoblastic neoplasia (GTN). The diagnostic of GTN must be done as early as possible through weekly surveillance of serum hCG after uterine evacuation.We report the case of 23-year-old primigravida, with CHM but without surveillance of hCG after uterine evacuation. Two months later, the patient presented to the emergency with vaginal bleeding and was referred to the Centro de Doenças Trofoblásticas do Hospital São Paulo. She was diagnosed with high risk GTN stage/score III:7 as per The International Federation of Gynecology and Obstetrics/World Health Organization (FIGO/WHO). The sonographic examination revealed enlarged uterus with a heterogeneous mass constituted of multiple large vessels invading and causing disarrangement of the myometrium. The patient evolved with progressive worsening of vaginal bleeding after chemotherapy with etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO) regimen. She underwent blood transfusion and embolization of uterine arteries due to severe vaginal hemorrhage episodes, with complete control of bleeding. The hCG reached a negative value after the third cycle, and there was a complete regression of the anomalous vascularization of the uterus as well as full recovery of the uterine anatomy. The treatment in a reference center was essential for the appropriate management, especially regarding the uterine arteries embolization trough percutaneous femoral

Key-words EMA-CO protocol Gestational trophoblastic disease Gestational trophoblastic neoplasia High risk pregnancy Uterine artery embolization
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Review Article
Management Strategies for Sexuality Complaints after Gynecologic Cancer: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(10):962-971
09-29-2022

Views144

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Review Article
Management Strategies for Sexuality Complaints after Gynecologic Cancer: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(10):962-971
09-29-2022
DOI 10.1055/s-0042-1756312
Luciane Machado Pizetta ,
Augusto da Cunha Reis ,
Mirian Picinini Méxas ,
Vanessa de Almeida Guimarães ,
Carmen Lucia de Paula
Views144
Abstract

Objective

To explore the main sexuality complaints of gynecologic cancer survivors after treatment and to identify the care strategies provided.

Data Source

Searches were conducted in six electronic databases: Scopus, Web of Science, LILACS, MEDLINE, PsychINFO, and EMBASE.

Study Selection

Articles published between 2010 and 2020 were selected and the following descriptors were used in the English language: female genital neoplasms and gynaecological cancer. The methodological quality of the studies used the Mixed Methods Appraisal Tool (MMAT).

Data Collection

The primary data extracted were: names of the authors, year of publication, country of origin, objective and type of study, data collection instrument, sample size and age range, types of cancer, and symptoms affected with the strategies adopted.

Data Summary

A total of 34 out of 2,536 screened articles were included. The main strategies found for patient care were patient-clinician communication, practices for sexuality care, individualized care plan, multiprofessional team support, and development of rehabilitation programs. For sexuality care, the most common practices are pelvic physiotherapy sessions and the use of vaginal gels and moisturizers.

Conclusion

The main complaints identified in the scientific literature were low libido and lack of interest in sexual activity, vaginal dryness, pain during sexual intercourse, and stenosis. Different care strategies may be adopted, such as follow-up with a multidisciplinary health team and sexual health rehabilitation programs, which could minimize these symptoms and ensure the quality of life of patients.

Key-words gynecological cancer Sexuality supportive care needs Survivors
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FEBRASGO POSITION STATEMENT
Abnormal uterine bleeding and chronic iron deficiency: Number 11 – December 2022
- Venina Viana de Barros ,
- Eliane Azeka Hase ,
- Cristiano Caetano Salazar ,
- Ana Maria Kondo Igai ,
- Fernanda Andrade Orsi ,
- Paulo Francisco Ramos Margarido
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(12):1161-1168
03-24-2022

Views198

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
FEBRASGO POSITION STATEMENT
Abnormal uterine bleeding and chronic iron deficiency: Number 11 – December 2022
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(12):1161-1168
03-24-2022
DOI 10.1055/s-0042-1760235
Venina Viana de Barros ,
Eliane Azeka Hase ,
Cristiano Caetano Salazar ,
Ana Maria Kondo Igai ,
Fernanda Andrade Orsi ,
Paulo Francisco Ramos Margarido
Views198
Key points[…]
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Review Article
Non-pharmacological Interventions for Improving Sleep Quality During Pregnancy: A Systematic Review and Meta-Analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(8):776-784
05-23-2022

Views208

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Review Article
Non-pharmacological Interventions for Improving Sleep Quality During Pregnancy: A Systematic Review and Meta-Analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(8):776-784
05-23-2022
DOI 10.1055/s-0042-1746200
Daiane Sofia Morais Paulino ,
Carolina Bicudo Borrelli ,
Débora Bicudo Faria-Schützer ,
Luiz Gustavo Oliveira Brito ,
Fernanda Garanhani Surita
Views208
Abstract

Objective

To investigate the effect of non-pharmacological interventions to improve sleep quality during pregnancy.

Data sources

A search was made in the NCBI/PubMed, ClinicalTrials.gov, Embase, BVS, and Web of Science databases. There were no limitations regarding language, sample size, and type of non-pharmacological intervention. We have included prospective clinical trials between July 2014 and July 2019.

Selection of studies

This study was registered in the Prospective International Registration of Systematic Reviews (PROSPERO) database was performed. Publication bias was also assessed with funnel plots. the primary outcome was the total score in the Pittsburgh Sleep Quality Index (PSQI) before and after intervention. Risk of bias and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria were used for assessing methodological quality. From the 28 retrieved studies, we have selected 8 for qualitative analysis and 6 for meta-analysis.

Data collection

Two independent reviewers performed the study selection. In the case of disagreement, a third senior reviewer was consulted. The study was initially assessed based on the title, followed by abstract. Lastly, the full text was assessed to be included.

Data Synthesis

A significant improvement on the sleep quality (PSQI score) was observed when all interventions were grouped (MD = -3.03, 95%CI -4.15 to -1.92, n= 623, i²= 84%, p< 0.001). Analysis by subgroup (music listening: MD = -1.96, 95% CI -3.27 to -0.65, n= 207, i²= 67%, p= 0.003 and other interventions: MD = -3.66, 95% CI -4.93 to -2.40, n= 416, i2 = 80%, p< 0.001) showed an improvement, with high heterogeneity. Risk of bias has shown performance and detection bias for almost studies, and GRADE evidence was very low for all analyzed variables.

Conclusion

Non-pharmacological interventions—listening to music, physical exercise, relaxation exercises, lettuce seed, sleep hygiene, and acupressure—are effective for improving sleep quality during pregnancy.

Key-words Meta-analysis non-pharmacological interventions Pregnant women sleep quality systematic review
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Original Article
Increment of Maternal Mortality Among Admissions for Childbirth in Low-risk Pregnant Women in Brazil: Effect of COVID-19 Pandemic?
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(8):740-745
07-07-2022

Views139

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Increment of Maternal Mortality Among Admissions for Childbirth in Low-risk Pregnant Women in Brazil: Effect of COVID-19 Pandemic?
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(8):740-745
07-07-2022
DOI 10.1055/s-0042-1751059
Bruna Depieri Michels ,
Daniela Ferreira D’Agostini Marin ,
Betine Pinto Moehlecke Iser
Views139
Abstract

Objective

To assess the possible impact of the COVID-19 pandemic on maternal mortality among admissions for childbirth in 2020 in relation of the last 10 years.

Methods

An ecological study with pregnant women who underwent hospital births at the Brazilian unified public health service (SUS, in the Portuguese acronym) in Brazil from 2010 to 2020. The mortality among admissions for childbirth was obtained based on the number of admissions for childbirth with reported death as outcome divided by the total number of admissions. The underlying gestational risk and route of delivery were considered based on the national surveillance system. The average mortality for the period between 2010 and 2019 (baseline) was compared with the rate of deaths in 2020 (1^st pandemic year); the rate ratio was interpreted as the risk of death in 2020 in relation to the average of the previous period (RR), with 95% confidence intervals (CIs).

Results

In 2020, the 1^st year of the COVID-19 pandemic, 1,821,775 pregnant women were hospitalized for childbirth and 651 deaths were reported, which represents 8.7% of the total hospitalizations and 11.3% of maternal deaths between 2010 and 2020. There was an increase in maternal mortality after births in 2020 compared with the average for the period between 2010 and 2019, specially in low-risk pregnancies, both in vaginal (RR = 1.60; 95%CI:1.39–1.85) and cesarean births (RR = 1.18; 95%CI:1.04–1.34).

Conclusion

Maternal mortality among admissions for childbirth according to SUS data increased in 2020 compared with the average between 2010 and 2019, with an increment of 40% in low-risk pregnancies. The increase was of 18% after cesarean section and of 60% after vaginal delivery.

Key-words COVID-19 health impact assessment maternal Mortality Postpartum period
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Original Article
Habits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):169-177
04-08-2022

Views274

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Summary
Original Article
Habits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):169-177
04-08-2022
DOI 10.1055/s-0041-1741536
Marcela Grigol Bardin ,
Paulo César Giraldo ,
Cristina Laguna Benetti-Pinto ,
José Marcos Sanches ,
Camila Carvalho de Araujo ,
Rose Luce Gomes do Amaral
Views274
Abstract

Objective

To evaluate genital hygiene among women with and without bacterial vaginosis (BV) and/or vulvovaginal candidiasis (VVC).

Methods

A cross-sectional study of reproductive-aged women who underwent gynecological and laboratory tests and fulfilled a genital hygiene questionnaire.

Results

This study evaluated 166 healthy controls and 141 women diagnosed with either BV (n=72), VVC (n=61), or both (n=8). The use of intimate soap and moist wipes after urination was more frequent among healthy women (p=0.042 and 0.032, respectively). Compared to controls, bactericidal soap was more used by women with BV (p=0.05).

Conclusion

Some hygiene habits were associated to BV and/or VVC. Clinical trials should address this important issue in women’s health.

Key-words Bacterial vaginosis Candida albicans disbiosis hygiene Sexual behavior
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Outcomes after elevation of serratus anterior fascia flap versus serratus muscle flap in direct-to-implant breast reconstruction following mastectomy: a prospective study

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Screening of Perinatal Depression Using the Edinburgh Postpartum Depression Scale

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The Female Athlete Triad/Relative Energy Deficiency in Sports (RED-S)

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Efficacy of Hormonal and Nonhormonal Approaches to Vaginal Atrophy and Sexual Dysfunctions in Postmenopausal Women: A Systematic Review

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Placental Findings in Preterm and Term Preeclampsia: An Integrative Review of the Literature

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Conclusion

Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations

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Management Strategies for Sexuality Complaints after Gynecologic Cancer: A Systematic Review

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Abnormal uterine bleeding and chronic iron deficiency: Number 11 – December 2022

Non-pharmacological Interventions for Improving Sleep Quality During Pregnancy: A Systematic Review and Meta-Analysis

Abstract

Objective

Data sources

Selection of studies

Data collection

Data Synthesis