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Editorial
Ética em pesquisa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(9):494-494
04-09-1998
Views45This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
EditorialÉtica em pesquisa
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(9):494-494
04-09-1998This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Estudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):424-424
04-09-1998
Views40This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesEstudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):424-424
04-09-1998DOI 10.1590/S0100-72031998000700011
Views40Estudo Controlado e Randomizado para Prevenção de Infecção Pós-Cesárea com Penicilina e Cefalotina […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Estudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-423
04-09-1998
Views35This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesEstudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-423
04-09-1998DOI 10.1590/S0100-72031998000700009
Views35Estudo Morfológico e Morfométrico do Endométrio de Mulheres na Pós-Menopausa Durante Terapêutica Estrogênica Contínua, Associada ao Acetato de Medroxiprogesterona a Cada Dois, Três e Quatro Meses[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Sangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada – Recife (PE)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-424
04-09-1998
Views39This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesSangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada – Recife (PE)
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):423-424
04-09-1998DOI 10.1590/S0100-72031998000700010
Views39Sangramento e Endometrite em Pacientes Portadoras de DIU Pós-Placentário na Maternidade de Encruzilhada Recife (PE) […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Relato de Caso
Complete Mole in Twin Pregnancy: a Case Report
- Izildinha Maestá,
- Iracema M.P. Calderon,
- Marilza V.C. Rudge,
- Magaly M. Sales,
- Fabiano P. Saggioro, [ … ],
- José Carlos Peraçoli
04-09-1998
Views72This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Relato de CasoComplete Mole in Twin Pregnancy: a Case Report
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):415-419
04-09-1998DOI 10.1590/S0100-72031998000700008
- Izildinha Maestá,
- Iracema M.P. Calderon,
- Marilza V.C. Rudge,
- Magaly M. Sales,
- Fabiano P. Saggioro,
- José Carlos Peraçoli
Views72Twin pregnancy in which a normal fetus and a complete mole develop at the same time is a rare event. Clinical complications and malignancy are frequent in this type of disease.This report is about a case of a late diagnosis due to the presence of the fetus. The diagnosis was made when the pregnancy was interrupted and then confirmed by histopathological study and flow cytometry. The pregnancy was terminated transpelvically due to massive uterine hemorrhage. The post-molar follow-up showed the persistence of high levels of bhCG. The patient’s complete recovery was achieved after the administration of methotrexate. The diagnosis, natural history, and procedures for this rare disease are discussed in view of this case.
Key-words ChemotherapyComplete hydatidiform moleGestational trophoblastic diseaseHemorrhagePregnancy complicationsTwin pregnancyUltrasonographySee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Relato de Caso
Clear Cell Adenocarcinoma of the Endocervix in a 7-year-old Child
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):411-414
04-09-1998
Views86This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Relato de CasoClear Cell Adenocarcinoma of the Endocervix in a 7-year-old Child
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):411-414
04-09-1998DOI 10.1590/S0100-72031998000700007
Views86See moreClear cell adenocarcinoma of the vagina and cervix is a rare disease associated commonly with the use of diethylstilbestrol (DES) during pregnancy. The most commom complaint is irregular vaginal bleeding, which could be confused with vaginitis in children and abnormalities in the hypothalamic-pituitary axis in adolescents. We report a case of clear cell adenocarcinoma of the endocervix in a 7-year-old child who was attended at the Children and Adolescent Gynecology Sector, and we call attention to the diagnosis of genital cancer which, in spite of its rarity at this age, must be considered in children with genital bleeding.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Equipamentos e Métodos
Endometrial Resection by Video-Hysteroscopy: experience in a Teaching Hospital
- Caio Parente Barbosa,
- Marcelo Ettruri Santos,
- Ana Cristina Napolitano,
- Paula Harue Tamanaka,
- Emerson Barchi Cordts
04-09-1998
Views78This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Equipamentos e MétodosEndometrial Resection by Video-Hysteroscopy: experience in a Teaching Hospital
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):405-410
04-09-1998DOI 10.1590/S0100-72031998000700006
- Caio Parente Barbosa,
- Marcelo Ettruri Santos,
- Ana Cristina Napolitano,
- Paula Harue Tamanaka,
- Emerson Barchi Cordts
Views78See moreObjective: to demonstrate the effectiveness of video-hysteroscopic endometrial resection in the treatment of abnormal uterine bleeding. Patients and method: The authors studied 60 records of patients with abnormal uterine bleeding who did not respond to clinical treatment. Results: eighty-eight percent of the patients had adequate response to the treatment (53% oligomenorrhea and 35% amenorrhea). The complication rate was 8.3% (5 uterine perforations). Conclusion: video-hysteroscopic endometrial resection is an effective technique to treat abnormal uterine bleeding which failed to respond to clinical management. The intra and postoperative complication rates are low.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Maternal Mortality in São Paulo City in 1996
- Luis Carlos Pazero,
- Paulo Afonso Ferrigno Marcus,
- Carlos Eduardo Pereira Vega,
- Krikor Boyaciyan,
- Sônia Antonini Barbosa
04-09-1998
Views103This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisMaternal Mortality in São Paulo City in 1996
Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(7):395-403
04-09-1998DOI 10.1590/S0100-72031998000700005
- Luis Carlos Pazero,
- Paulo Afonso Ferrigno Marcus,
- Carlos Eduardo Pereira Vega,
- Krikor Boyaciyan,
- Sônia Antonini Barbosa
Views103Purpose: to establish a list of diseases promoting maternal death according to frequency. Methods: In 1996, 65,406 deaths were recorded in the City of São Paulo, 26,778 of which were of women. Of these, 4591 were within the 10-49 year age bracket. We analyzed the latter group, regarding at the field “Cause of Death” in the Death Certificate, trying to establish some correlation between the described pathology, and the pregnancy-puerperium cycle. We separated for a further study 293 Death Certificates, from which we selected, after hospital survey and/or home visits, a total of 119 positive cases for maternal death. The positive cases for maternal death were then tabulated, grouped and analyzed according to age and pathology, using the great medical care groups. Results: as regards the 119 positive cases for maternal death, we did not find any reference to the pregnancy-puerperium state in 53 of them (that is, 40.54% subnotifying). The cases were grouped according to pathology, where we found a predominance of eclampsia/pre-eclampsia cases (18.02%), followed by cases resulting from hemorrhagic complications in the third quarter and puerperium (12.61%), abortion complications (12.61%), puerperal infection (9.91%) and cardiopathies (9.91%). Conclusions: for the first time, we are publishing the Late Maternal Mortality Coefficient for the City of São Paulo, which was 51.33/100,000 born alive. However, we used for the official publication the Maternal Mortality Coefficient for death within up to 42 days of puerperium, which was, 48.03/100,000 born alive for the city of São Paulo. We should bear in mind that no correction factor should be applied to these figures since we have made an active search of cases.
Key-words Cardiopathy in pregnancyEclampsiaHemorrhagic complications in pregnancyMaternal mortalityMaternal mortality coefficientPregnancy complicationsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article
Screening and prevention of preterm birth: how is it done in clinical practice?
- Roberta Bulsing dos Santos
,
- Janete Vettorazzi
,
- Marcos Wengrover Rosa
,
- Ellen Machado Arlindo
,
- Edimárlei Gonsales Valério
04-09-2024
Summary
Original ArticleScreening and prevention of preterm birth: how is it done in clinical practice?
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo32
04-09-2024- Roberta Bulsing dos Santos
,
- Janete Vettorazzi
,
- Marcos Wengrover Rosa
,
- Ellen Machado Arlindo
,
- Edimárlei Gonsales Valério
Views486Abstract
Objective:
To ascertain how screening for preterm birth is performed among obstetricians working in public and private practice in a middle-income country.
Methods:
Cross-sectional study of 265 obstetrician-gynecologists employed at public and private facilities. An online questionnaire was administered, with items designed to collect data on prematurity screening and prevention practices.
Results:
The mean age of respondents was 44.5 years; 78.5% were female, and 97.7% had completed a medical residency program. Universal screening (i.e., by ultrasound measurement of cervical length) was carried out by only 11.3% of respondents in public practice; 43% request transvaginal ultrasound if the manual exam is abnormal, and 74.6% request it in pregnant women with risk factors for preterm birth. Conversely, 60.7% of respondents in private practice performed universal screening. This difference in screening practices between public and private practice was highly significant (p < 0.001). Nearly all respondents (90.6%) reported prescribing vaginal progesterone for short cervix.
Conclusion:
In the setting of this study, universal ultrasound screening to prevent preterm birth was used by just over half of doctors in private practice. In public facilities, screening was even less common. Use of vaginal progesterone in cervical shortening was highly prevalent. There is an unmet need for formal protocols for screening and prevention of preterm birth in middle-income settings.
Key-words attitudes, practiceCervical length measurementgynecologistshealth knowledgeInfant, prematureobstetriciansPreterm birthPreventionScreeningsurveys and questionnairesSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Roberta Bulsing dos Santos
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Original Article
Transforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis
- Andreia Jacobo
,
- Renata Fogaça Borges
,
- Carlos Augusto Bastos de Souza
,
- Vanessa Krebs Genro
,
- João Sabino Cunha-Filho
04-09-2024
Views460This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleTransforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo31
04-09-2024- Andreia Jacobo
,
- Renata Fogaça Borges
,
- Carlos Augusto Bastos de Souza
,
- Vanessa Krebs Genro
,
- João Sabino Cunha-Filho
Views460See moreAbstract
Objective:
To compare Transforming growth factor beta-1 (TGF-β1) expression in patients with and without adenomyosis.
Methods:
A prospective design was performed including 49 patients submitted to hysterectomy. Immunohistochemistry was performed on anatomopathological samples staged in paraffin blocks from patients with and without adenomyosis. The sample contained 28 adenomyosis cases and 21 controls. Student’s t-test and multivariate logistic regression tests were used for statistical analysis. Associations were considered significant at p < 0.05.
Results:
We found no significant association between adenomyosis and: smoking (p = 0.75), miscarriage (p = 0.29), number of previous pregnancies (p = 0.85), curettage (p = 0.81), pelvic pain (p = 0.72) and myoma (p = 0.15). However, we did find a relationship between adenomyosis and abnormal uterine bleeding (AUB) (p = 0.02) and previous cesarean section (p = 0.02). The mean TGF-β1 intensity (mean ± SD) in the ectopic endometrium of women with adenomyosis showed no significant association (184.17 ± 9.4 vs.184.66 ± 16.08, p = 0.86) from the topic endometrium of women without adenomyosis.
Conclusion:
TGF-β1 expression was not increased in the ectopic endometrium of women with adenomyosis.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Andreia Jacobo
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Original Article
Prevalence and factors associated with anxiety, depression and burnout in gynecology and obstetrics residents during the COVID-19 pandemic
- Maria Luiza de Castro Amaral
,
- Isabela Michel da Silva
,
- Alexandre Ferreira Bello
,
- Franciele Cascaes da Silva
,
- Gustavo Salata Romão
,
[ … ], - Alberto Trapani Júnior
00-00-2024
Views457This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticlePrevalence and factors associated with anxiety, depression and burnout in gynecology and obstetrics residents during the COVID-19 pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo17
00-00-2024- Maria Luiza de Castro Amaral
,
- Isabela Michel da Silva
,
- Alexandre Ferreira Bello
,
- Franciele Cascaes da Silva
,
- Gustavo Salata Romão
,
- Alberto Trapani Júnior
Views457Abstract
Objective:
To determine the prevalence of anxiety, depression and burnout in residents of Gynecology and Obstetrics during COVID-19 pandemic in Brazil and its associated factors.
Methods:
Cross-sectional study involving all regions of Brazil, through the application of a sociodemographic questionnaire, the Hospital Anxiety and Depression Scale (HAD) and the Maslach Burnout Inventory (MBI-HSS) instrument. Multivariate analysis was performed after adjusting the Poisson model.
Results:
Among the 719 participating medical residents, screening was positive for anxiety in 75.7% and for depression in 49.8% of cases. Burnout syndrome was evidenced in 41.3% of the physicians studied. Those with depression are more likely to have anxiety (OR 0.797; 95%CI 0.687 – 0.925) and burnout syndrome (OR 0.847 95%CI 0.74 – 0.97). Residents with anxiety (OR 0.805; 95%CI 0.699 – 0.928) and burnout (OR 0.841; 95%CI 0.734 – 0.963) are more likely to have depression.
Conclusion:
High prevalence of anxiety, depression and burnout were found in residents of Gynecology and Obstetrics in Brazil, in addition to important correlations between anxiety-depression and depression-burnout.
Key-words AnxietyBrazilBurnout, psychologicalCOVID-19DepressionGynecologyinternship and residencymedical residencyMental healthObstetricspandemicsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Maria Luiza de Castro Amaral
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Original Article
Gender affirming hormone therapy and transgender women fertility: Histologic predictors of germ cell presence
- Lina Rigodanzo Marins
,
- Tiago Elias Rosito
,
- Lucia Maria Kliemann
,
- Edson Capp
,
- Helena von Eye Corleta
04-09-2024
Views455This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleGender affirming hormone therapy and transgender women fertility: Histologic predictors of germ cell presence
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo33
04-09-2024- Lina Rigodanzo Marins
,
- Tiago Elias Rosito
,
- Lucia Maria Kliemann
,
- Edson Capp
,
- Helena von Eye Corleta
Views455Abstract
Objective:
Evaluate histological changes in testicular parameters after hormone treatment in transgender women.
Methods:
Cross-section study with patients who underwent gonadectomy at Hospital de Clínicas de Porto Alegre from 2011 to 2019. Hormone treatment type, route of administration, age at initiation and duration were recorded. Atrophy parameters were observed: testicular volume, tubular diameter, basal membrane length, presence of spermatogonia and spermatids (diploid and haploid spermatozoid precursors).
Results:
Eighty-six patients were included. Duration of hormone treatment is associated with testicular atrophy and spermatogenesis arrest. Other characteristics of hormone treatment such as age of initiation, route of administration and type of treatment were not associated with testicular histological changes. Testicular volume may predict spermatogenesis arrest. Basal membrane length and tubular diameter ratio is an interesting predictor of germ cell presence.
Conclusion:
Cross-sex hormone treatment affects testicular germ cell presence. Basal membrane length and tubular diameter ratio reduces inter variability of measurements and better exemplify how atrophic seminiferous tubules are. Fertility preservation should be addressed by healthcare providers in order to recognize gender affirming treatment impact on transgender health.
Key-words FertilityFertility preservationGonadal steroid hormonesHormone treatmentSpermatogenesisTransgender personsTransgender womenSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Lina Rigodanzo Marins
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Original Article
Association of placental histopathological findings with COVID-19 and its predictive factors
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo3
00-00-2024
Views447This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleAssociation of placental histopathological findings with COVID-19 and its predictive factors
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo3
00-00-2024Views447See moreAbstract
Objective:
The aims of the study are to describe the association of coronavirus disease (COVID-19) with the abnormal histopathological findings in human placenta and to highlight the potential predictors of these histopathological findings.
Methods:
A retrospective cohort study, held in two obstetric units from January 2021- 2022, 34 patients who were confirmed cases of COVID- 19 were followed up till the time of delivery as their placenta were sent for histopathology. Patients diagnosed with other viral infections, chorioamnionitis, or were known case of as pre-term or term pre labour rupture of membrans (PROM) were excluded as well as pre exisiting diabetes mellitus or pre-eclampsia. Data analysis were performed using STATA software version 16.
Result:
Specific histopatological findings (fetal vascular malperfusion, maternal vascular malperfusion, inflammatory pathology and thrombotic finding) were significantly high among 13 (38.2%) of the study group who got infected earlier in pregnancy (P<0.001). The period between the diagnosis of COVID-19 and the delivery significantly increases the odds of the presence of pathological findings by 2.75 times for each week the patients getting infected earlier.
Conclusion:
Association of abnormal placental histopathological findings with COVID-19 infection in pregnancy and the potential predictor for the occurrence of placental findings is the longer duration between the diagnosis of the infection and the delivery.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article
Translation, cross-cultural adaptation to Brazilian Portuguese and measurement properties of the WaLIDD score
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo16
00-00-2024
Summary
Original ArticleTranslation, cross-cultural adaptation to Brazilian Portuguese and measurement properties of the WaLIDD score
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo16
00-00-2024Views434See moreAbstract
Objective:
Dysmenorrhea is the pain related to menstruation; to screen for the symptoms, a working ability, location, intensity of days of pain, and dysmenorrhea (WaLIDD) score was created. The purpose of this work was to culturally adapt and assess the measurement properties of the WaLIDD score for dysmenorrhea in Brazilian women.
Methods:
In this cross-sectional online study, we evaluated women with and without dysmenorrhea. Criterion validity and construct validity were assessed, respectively, by the Receiver Operator Characteristic (ROC) curve and correlations with the bodily pain and social functioning domains of medical outcomes study 36-item short-form health survey (SF-36), self-report of absenteeism and Stanford Presenteeism Scale for presenteeism. Test-retest reliability and measurement errors were assessed, respectively, by intraclass correlation coefficient (ICC) and Bland and Altman Graph.
Results:
430 women completed the test, 238 (55.4%) women had dysmenorrhea, and 199 (46.3%) answered the questionnaire twice for the retest. The cutoff points ≥4, ≥5, and ≥5 could discriminate between women with and without dysmenorrhea, absenteeism, and presenteeism related to dysmenorrhea, respectively. Correlations between SF-36 – pain and social functioning domains and WaLIDD score were weak to strong and negative. For WaLIDD total Score, ICC was 0.95 and the limits of agreement were −1.54 and 1.62.
Conclusion:
WaLIDD score is a short, valid and reliable instrument to screen and predict dysmenorrhea and could predict absenteeism and presenteeism related to dysmenorrhea in Brazilian women.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article
Postpartum hemorrhage in electronic health records: risk factors at admission and in-hospital occurrence
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo14
00-00-2024
Views429This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticlePostpartum hemorrhage in electronic health records: risk factors at admission and in-hospital occurrence
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo14
00-00-2024Views429Abstract
Objective:
Postpartum hemorrhage (PPH) is the leading cause of maternal death globally. Therefore, prevention strategies have been created. The study aimed to evaluate the occurrence of PPH and its risk factors after implementing a risk stratification at admission in a teaching hospital.
Methods:
A retrospective cohort involving a database of SISMATER® electronic medical record. Classification in low, medium, or high risk for PPH was performed through data filled out by the obstetrician-assistant. PPH frequency was calculated, compared among these groups and associated with the risk factors.
Results:
The prevalence of PPH was 6.8%, 131 among 1,936 women. Sixty-eight (51.9%) of them occurred in the high-risk group, 30 (22.9%) in the medium-risk and 33 (25.2%) in the low-risk group. The adjusted-odds ratio (OR) for PPH were analyzed using a confidence interval (95% CI) and was significantly higher in who presented multiple pregnancy (OR 2.88, 95% CI 1.28 to 6.49), active bleeding on admission (OR 6.12, 95% CI 1.20 to 4.65), non-cephalic presentation (OR 2.36, 95% CI 1.20 to 4.65), retained placenta (OR 9.39, 95% CI 2.90 to 30.46) and placental abruption (OR 6.95, 95% CI 2.06 to 23.48). Vaginal delivery figured out as a protective factor (OR 0.58, 95% CI 0.34 to 0.98).
Conclusion:
Prediction of PPH is still a challenge since its unpredictable factor arrangements. The fact that the analysis did not demonstrate a relationship between risk category and frequency of PPH could be attributable to the efficacy of the strategy: Women classified as “high-risk” received adequate medical care, consequently.
Key-words Electronic health recordsMaternal mortalityPostpartum hemorrhagePuerperal disordersRisk factorsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article
Vascular contraction of umbilical arteries of pregnant women with preeclampsia
- Gabriela Morelli Zampieri
,
- Priscila Rezeck Nunes
,
- Joelcio Francisco Abbade
,
- Carlos Alan Dias Junior
,
- Valeria Cristina Sandrim
00-00-2024
Views413This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleVascular contraction of umbilical arteries of pregnant women with preeclampsia
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo2
00-00-2024- Gabriela Morelli Zampieri
,
- Priscila Rezeck Nunes
,
- Joelcio Francisco Abbade
,
- Carlos Alan Dias Junior
,
- Valeria Cristina Sandrim
Views413See moreAbstract
Objective:
Potassium channels have an important role in the vascular adaptation during pregnancy and a reduction in the expression of adenosine triphosphate-sensitive potassium channels (Katp) has been linked to preeclampsia. Activation of Katp induces vasodilation; however, no previous study has been conducted to evaluate the effects of the inhibition of these channels in the contractility of preeclamptic arteries. Glibenclamide is an oral antihyperglycemic agent that inhibits Katp and has been widely used in vascular studies.
Methods:
To investigate the effects of the inhibition of Katp, umbilical arteries of preeclamptic women and women with healthy pregnancies were assessed by vascular contractility experiments, in the presence or absence of glibenclamide. The umbilical arteries were challenged with cumulative concentrations of potassium chloride (KCl) and serotonin.
Results:
There were no differences between the groups concerning the maternal age and gestational age of the patients. The percentage of smokers, caucasians and primiparae per group was also similar. On the other hand, blood pressure parameters were elevated in the preeclamptic group. In addition, the preeclamptic group presented a significantly higher body mass index. The newborns of both groups presented similar APGAR scores and weights.
Conclusion:
In the presence of glibenclamide, there was an increase in the KCl-induced contractions only in vessels from the PE group, showing a possible involvement of these channels in the disorder.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Gabriela Morelli Zampieri
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Original Article
Habits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
- Marcela Grigol Bardin
,
- Paulo César Giraldo
,
- Cristina Laguna Benetti-Pinto
,
- José Marcos Sanches
,
- Camila Carvalho de Araujo
,
[ … ], - Rose Luce Gomes do Amaral
04-08-2022
Views281This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleHabits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):169-177
04-08-2022- Marcela Grigol Bardin
,
- Paulo César Giraldo
,
- Cristina Laguna Benetti-Pinto
,
- José Marcos Sanches
,
- Camila Carvalho de Araujo
,
- Rose Luce Gomes do Amaral
Views281See moreAbstract
Objective
To evaluate genital hygiene among women with and without bacterial vaginosis (BV) and/or vulvovaginal candidiasis (VVC).
Methods
A cross-sectional study of reproductive-aged women who underwent gynecological and laboratory tests and fulfilled a genital hygiene questionnaire.
Results
This study evaluated 166 healthy controls and 141 women diagnosed with either BV (n=72), VVC (n=61), or both (n=8). The use of intimate soap and moist wipes after urination was more frequent among healthy women (p=0.042 and 0.032, respectively). Compared to controls, bactericidal soap was more used by women with BV (p=0.05).
Conclusion
Some hygiene habits were associated to BV and/or VVC. Clinical trials should address this important issue in women’s health.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Marcela Grigol Bardin
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Original Article
Temporal Evolution of Maternal Mortality: 1980-2019
- Janete Vettorazzi
,
- Edimárlei Gonsales Valério
,
- Maria Alexandrina Zanatta
,
- Mariana Hollmann Scheffler
,
- Sergio Hofmeister de Almeida Martins Costa
,
[ … ], - José Geraldo Lopes Ramos
11-29-2021
Views184This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleTemporal Evolution of Maternal Mortality: 1980-2019
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(9):662-668
11-29-2021- Janete Vettorazzi
,
- Edimárlei Gonsales Valério
,
- Maria Alexandrina Zanatta
,
- Mariana Hollmann Scheffler
,
- Sergio Hofmeister de Almeida Martins Costa
,
- José Geraldo Lopes Ramos
Views184Abstract
Objective
To determine the profile of maternal deaths occurred in the period between 2000 and 2019 in the Hospital de Clínicas de Porto Alegre (HCPA, in the Portuguese acronym) and to compare it with maternal deaths between 1980 and 1999 in the same institution.
Methods
Retrospective study that analyzed 2,481 medical records of women between 10 and 49 years old who died between 2000 and 2018. The present study was approved by the Ethics Committee (CAAE 78021417600005327).
Results
After reviewing 2,481 medical records of women who died in reproductive age, 43 deaths had occurred during pregnancy or in the postpartum period. Of these, 28 were considered maternal deaths. The maternal mortality ratio was 37.6 per 100,000 live births. Regarding causes, 16 deaths (57.1%) were directly associated with pregnancy, 10 (35.1%) were indirectly associated, and 2 (7.1%) were unrelated. The main cause of death was hypertension during pregnancy (31.2%) followed by acute liver steatosis during pregnancy (25%). In the previous study, published in 2003 in the same institution4, the mortality rate was 129 per 100,000 live births, and most deaths were related to direct obstetric causes (62%). The main causes of death in this period were due to hypertensive complications (17.2%), followed by postcesarean infection (16%).
Conclusion
Compared with data before the decade of 2000, there was an important reduction in maternal deaths due to infectious causes.
Key-words acute fatty liver of pregnancyMaternal mortalitymaternal mortality ratiopostcesarean infectionpregnancy hypertensionpregnancy-related deathSeptic abortionsevere maternal morbiditySee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Janete Vettorazzi
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Review Article
Relation between Selenium and Female Fertility: A Systematic Review
- Luiz Gustavo Lima
,
- André Amaro Mamédio dos Santos
,
- Tiago Daniel Gueiber
,
- Ricardo Zanetti Gomes
,
- Camila Marinelli Martins
,
[ … ], - Andrielle Cristina Chaikoski
06-03-2022
Views254This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleRelation between Selenium and Female Fertility: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(7):701-709
06-03-2022- Luiz Gustavo Lima
,
- André Amaro Mamédio dos Santos
,
- Tiago Daniel Gueiber
,
- Ricardo Zanetti Gomes
,
- Camila Marinelli Martins
,
- Andrielle Cristina Chaikoski
Views254See moreAbstract
Objective
To analyze the influence of selenium in female fertility.
Conclusion
Selenium supplementation is promising in women with this micronutrient deficiency to promote improvement of the reproductive efficiency and prevent damage to the pregnancy. Further studies on this theme are still required.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Luiz Gustavo Lima
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Review Article
Clinical Features and Maternal-fetal Results of Pregnant Women in COVID-19 Times
- Ana Paula Nogueira Godoi
,
- Gilcelia Correia Santos Bernardes
,
- Leilismara Sousa Nogueira
,
- Patrícia Nessralla Alpoim
,
- Melina de Barros Pinheiro
07-30-2021
Views237This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleClinical Features and Maternal-fetal Results of Pregnant Women in COVID-19 Times
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):384-394
07-30-2021- Ana Paula Nogueira Godoi
,
- Gilcelia Correia Santos Bernardes
,
- Leilismara Sousa Nogueira
,
- Patrícia Nessralla Alpoim
,
- Melina de Barros Pinheiro
Views237See moreAbstract
Objective
Coronavirus disease 2019 (COVID-19) is a disease caused by a newly discovered coronavirus, severe acute respiratory syndrome coronavirus 2 (SARSCoV-2), which usually leads to non-specific respiratory symptoms. Although pregnant women are considered at risk for respiratory infections by other viruses, such as SARS and Middle East respiratory syndrome (MERS), little is known about their vulnerability to SARS-CoV-2. Therefore, this study aims to identify and present the main studies on the topic, including the postpartum period.
Methods
In this narrative review, articles were searched in various databases, organizations, and health entities using keywords compatible with medical subject headings (MeSH), such as: COVID-19, pregnancy, vertical transmission, coronavirus 2019, and SARS-CoV-2.
Results
The review of the scientific literature on the subject revealed that pregnant women with COVID-19 did not present clinical manifestations significantly different from those of non-pregnant women; however, there are contraindicated therapies. Regarding fetuses, studies were identified that reported that infection by SARS-CoV-2 in pregnant women can cause fetal distress, breathing difficulties and premature birth, but there is no substantial evidence of vertical transmission.
Conclusion
Due to the lack of adequate information and the limitations of the analyzed studies, it is necessary to provide detailed clinical data on pregnant women infected with SARS-CoV-2 and on the maternal-fetal repercussions caused by this infection. Thus, this review may contribute to expand the knowledge of professionals working in the area as well as to guide more advanced studies on the risk related to pregnant women and their newborns. Meanwhile, monitoring of confirmed or suspected pregnant women with COVID-19 is essential, including in the postpartum period.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Ana Paula Nogueira Godoi
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Original Article
Levels and Predictors of Anxiety and Depression in Turkish PregnantWoman During the Covid-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):100-108
04-08-2022
Views174This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleLevels and Predictors of Anxiety and Depression in Turkish PregnantWoman During the Covid-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):100-108
04-08-2022Views174See moreAbstract
Objective
In addition to being a medical phenomenon, pandemics affect the individual and society on several levels and lead to disruptions. In the pandemic process, different groups in the population, including pregnant women as a defenseless group, are subjected to psychological threat. The present study aimed to determine the levels of anxiety and depression and related factors in pregnant women during the the coronavirus disease 2019 (Covid-19) pandemic.
Methods
The present cross-sectional study was conducted with 269 pregnant women through face-to-face interviews held in Istanbul, Turkey. Regarding the data collection tools, the Cronbach α reliability coefficient was of 0.90 for the Beck Anxiety Inventory, and of 0.85 for the Beck Depression Inventory.
Results
Among the participating pregnant women, 30.5% had mild, 17.5% had moderate, and 5.9% had severe anxiety symptoms, whereas 35.3% had mild, 16.7% had moderate, and 2.2% had severe depression symptoms. We found that those who were concerned about their health had 5.36 times (p=0.04) more risk of developing anxiety, and 4.82 times (p=0.01) more risk of developing depression than those who were not concerned. Those who had a history of psychiatric disease had 3.92 times (p=0.02) more risk of developing anxiety than those without it.
Conclusion
We determined that about half of the pregnant women included in the study had some degree of anxiety and depression during the COVID-19 pandemic. The risk factors for anxiety and depression among the pregnant women were determined as smoking, concerns about health and getting infectedwith the coronavirus, history of psychiatric disease, and undergoing regular antenatal care.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article
Risk Factors Associated with Uterine Rupture and Dehiscence: A Cross-Sectional Canadian Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(11):820-825
01-12-2021
Views182This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleRisk Factors Associated with Uterine Rupture and Dehiscence: A Cross-Sectional Canadian Study
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(11):820-825
01-12-2021Views182See moreAbstract
Objective
To compare maternal and perinatal risk factors associated with complete uterine rupture and uterine dehiscence.
Methods
Cross-sectional study of patients with uterine rupture/dehiscence from January 1998 to December 2017 (30 years) admitted at the Labor and Delivery Unit of a tertiary teaching hospital in Canada.
Results
There were 174 (0.1%) cases of uterine disruption (29 ruptures and 145 cases of dehiscence) out of 169,356 deliveries. There were associations between dehiscence and multiparity (odds ratio [OR]: 3.2; p=0.02), elevated maternal body mass index (BMI; OR: 3.4; p=0.02), attempt of vaginal birth after a cesarian section (OR: 2.9; p=0.05) and 5-minute low Apgar score (OR: 5.9; p<0.001). Uterine rupture was associated with preterm deliveries (36.5 ± 4.9 versus 38.2 ± 2.9; p=0.006), postpartum hemorrhage (OR: 13.9; p<0.001), hysterectomy (OR: 23.0; p=0.002), and stillbirth (OR: 8.2; p<0.001). There were no associations between uterine rupture and maternal age, gestational age, onset of labor, spontaneous or artificial rupture of membranes, use of oxytocin, type of uterine incision, and birthweight.
Conclusion
This large cohort demonstrated that there are different risk factors associated with either uterine rupture or dehiscence. Uterine rupture still represents a great threat to fetal-maternal health and, differently from the common belief, uterine dehiscence can also compromise perinatal outcomes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Editorial
Placenta Accreta Spectrum Disorders and Cesarean Scar Pregnancy Screening: Are we Asking the Right Questions?
- Conrado Milani Coutinho
,
- Laure Noel
,
- Veronica Giorgione
,
- Lígia Conceição Assef Marçal
,
- Amar Bhide
,
[ … ], - Basky Thilaganathan
07-30-2021
Views150This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
EditorialPlacenta Accreta Spectrum Disorders and Cesarean Scar Pregnancy Screening: Are we Asking the Right Questions?
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):347-350
07-30-2021- Conrado Milani Coutinho
,
- Laure Noel
,
- Veronica Giorgione
,
- Lígia Conceição Assef Marçal
,
- Amar Bhide
,
- Basky Thilaganathan
Views150What are the Relevant Risk Factors for Pas Screening?Numeroushistorical risk factors have been associated with the occurrence of PAS, including maternal obesity, advanced maternal age and parity, previous uterine surgery (including illegal terminations of pregnancy), and use of assisted reproductive technologies. However, there is no doubt that the concomitance of the only risk factor related […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Conrado Milani Coutinho
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Review Article
Main Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review
- Camilla Olivares Figueira
,
- Fernanda Garanhani Surita
,
- Kleber Fertrin
,
- Guilherme de Moraes Nobrega
,
- Maria Laura Costa
02-09-2022
Views247This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleMain Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(6):593-601
02-09-2022- Camilla Olivares Figueira
,
- Fernanda Garanhani Surita
,
- Kleber Fertrin
,
- Guilherme de Moraes Nobrega
,
- Maria Laura Costa
Views247See moreAbstract
Sickle cell disease (SCD) is the most common monogenic disease worldwide, with a variable prevalence in each continent. A single nucleotide substitution leads to an amino-acid change in the β-globin chain, altering the normal structure of hemoglobin, which is then called hemoglobin S inherited in homozygosity (HbSS) or double heterozygosity (HbSC, HbSβ), and leads to chronic hemolysis, vaso-occlusion, inflammation, and endothelium activation. Pregnant women with SCD are at a higher risk of developing maternal and perinatal complications. We performed a narrative review of the literature considering SCD and pregnancy, the main clinical and obstetrical complications, the specific antenatal care, and the follow-up for maternal and fetal surveillance. Pregnant women with SCD are at a higher risk of developing clinical and obstetric complications such as pain episodes, pulmonary complications, infections, thromboembolic events, preeclampsia, and maternal death. Their newborns are also at an increased risk of developing neonatal complications: fetal growth restriction, preterm birth, stillbirth. Severe complications can occur in patients of any genotype. We concluded that SCD is a high-risk condition that increases maternal and perinatal morbidity and mortality. A multidisciplinary approach during pregnancy and the postpartum period is key to adequately diagnose and treat complications.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Camilla Olivares Figueira
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