vaginismus Archives - Revista Brasileira de Ginecologia e Obstetrícia

  • Original Article

    Comparative Study of 150 vs. 200 Units of Botulinum Toxin as Treatment for Vaginismus

    Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(9):854-865

    Summary

    Original Article

    Comparative Study of 150 vs. 200 Units of Botulinum Toxin as Treatment for Vaginismus

    Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(9):854-865

    DOI 10.1055/s-0042-1751287

    Views9

    Abstract

    Objective

    To comparatively evaluate the outcome of treatment with 150 versus 200 units (U) of botulinum toxin in achieving pain-free intercourse and relieving muscle contraction in order to allow gynecological examination.

    Methods

    In this comparative prospective observational study, 99 patients with vaginismus were treated with botulinum toxin injections from September 2016 to August 2021. Diagnosis and grading of vaginismus severity were assessed using a Female Sexual Function Index (FSFI) questionnaire. Under local or general anesthesia, botulinum toxin diluted with preservative-free saline (150 U and 200 U) was injected into, above, and below the right and left bulbospongiosus muscle and the lateral submucosal areas of the introitus and perineal body using an insulin syringe. Patients were recalled after 2 weeks, and the postoperative outcome was recorded using a similar preoperative questionnaire.

    Results

    Overall, the mean age of patients was 30.2 years. The baseline and clinical characteristics were comparable between the 2 groups (p > 0.05). Significant improvements were seen in the pain and anxiety scores of finger penetration, dilator use, intercourse, and cotton swab in individual groups. The intergroup comparisons between 150 U and 200 U of Botox were not statistically significant (p > 0.05).

    Conclusion

    Low-dose Botox (150 U) is equally effective as high dose Botox injections (200 U) in vaginismus patients. Therefore, Botox-150 U can be used to treat vaginismus as an alternative to high doses of the same substance.

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    Comparative Study of 150 vs. 200 Units of Botulinum Toxin as Treatment for Vaginismus
  • Review Articles

    Female Genito-Pelvic Pain/Penetration Disorder: Review of the Related Factors and Overall Approach

    Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(12):787-793

    Summary

    Review Articles

    Female Genito-Pelvic Pain/Penetration Disorder: Review of the Related Factors and Overall Approach

    Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(12):787-793

    DOI 10.1055/s-0038-1675805

    Views15

    Abstract

    Genito-pelvic pain/penetration disorder (GPPPD) can be an extremely bothersome condition for patients, and a tough challenge for professionals regarding its assessment and treatment. The goal of the present paper is to review the etiology, assessment, and treatment of GPPPD, especially focusing on the cognitive aspects of the disease and cognitive-behavioral treatment options, through a non-systematic review of articles indexed to the Medline, Scopus and Web of Science databases, using the following MeSH queries: pelvic pain; dyspareunia; vaginismus; vulvodynia; and cognitive therapy. Altogether, 36 articles discussing the etiology, diagnosis and management of GPPPD were selected. We provide an overview of GPPPD based on biological, psychological and relational factors, emphasizing the last two. We also summarize the available medical treatments and provide strategies to approach the psychological trigger and persisting factors for the patient and the partner. Professionals should be familiarized with the factors underlining the problem, and should be able to provide helpful suggestions to guide the couple out of the GPPPD fear-avoidance circle.

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    Female Genito-Pelvic Pain/Penetration Disorder: Review of the Related Factors and Overall Approach

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