osteoporosis Archives - Revista Brasileira de Ginecologia e Obstetrícia
Summary
Rev Bras Ginecol Obstet. 2008;30(8):379-383
DOI 10.1590/S0100-72032008000800002
PURPOSE: to verify the association of osteoporosis with periodontal disease. METHODS: the study has included 39 postmenopausal women divided in three groups according to bone mass categories, through evaluation of mineral bone density (MBD), measured by X-ray double emission absorbimetry in the lumbar area (L1-L4): ): normal bone; osteopenia and osteoporosis. In all the participants the Clinical Insertion Level (CIL) index has been determined at the research onset and after one year, by the same examiner. The periodontal situation data have been submitted to statistical analysis with the paired t-Student test. RESULTS: the periodontal exam has shown that postmenopausal women in the osteopenia presented lower CIL at the initial periodontal clinical exam (2.1±1.1 mm), while the ones in the normal bone showed less teeth support tissue loss after one year (3.1±1.6 mm). The statistical analysis has shown that there was no significant difference for the periodontal situation in the normal bone, but there was significant statistical difference for the osteopenia and osteoporosis patients, when CIL values from both evaluation periods were compared. CONCLUSIONS: it is concluded that postmenopausal osteoporosis may be a possible risk factor for periodontal disease.
Summary
Rev Bras Ginecol Obstet. 2008;30(8):379-383
DOI 10.1590/S0100-72032008000800002
PURPOSE: to verify the association of osteoporosis with periodontal disease. METHODS: the study has included 39 postmenopausal women divided in three groups according to bone mass categories, through evaluation of mineral bone density (MBD), measured by X-ray double emission absorbimetry in the lumbar area (L1-L4): ): normal bone; osteopenia and osteoporosis. In all the participants the Clinical Insertion Level (CIL) index has been determined at the research onset and after one year, by the same examiner. The periodontal situation data have been submitted to statistical analysis with the paired t-Student test. RESULTS: the periodontal exam has shown that postmenopausal women in the osteopenia presented lower CIL at the initial periodontal clinical exam (2.1±1.1 mm), while the ones in the normal bone showed less teeth support tissue loss after one year (3.1±1.6 mm). The statistical analysis has shown that there was no significant difference for the periodontal situation in the normal bone, but there was significant statistical difference for the osteopenia and osteoporosis patients, when CIL values from both evaluation periods were compared. CONCLUSIONS: it is concluded that postmenopausal osteoporosis may be a possible risk factor for periodontal disease.
Summary
Rev Bras Ginecol Obstet. 2000;22(4):239-241
DOI 10.1590/S0100-72032000000400009
Osteoporosis is an important disease which can affect millions of patients all over the world, leading to complications, often even to death. Prevention and the early diagnosis may help in the success of treatment but there are diseases which can occur at the same time. Primary hyperparathyroidism is a diagnosis which must be remembered in women after the menopause.
Summary
Rev Bras Ginecol Obstet. 2000;22(4):239-241
DOI 10.1590/S0100-72032000000400009
Osteoporosis is an important disease which can affect millions of patients all over the world, leading to complications, often even to death. Prevention and the early diagnosis may help in the success of treatment but there are diseases which can occur at the same time. Primary hyperparathyroidism is a diagnosis which must be remembered in women after the menopause.
Summary
Rev Bras Ginecol Obstet. 2004;26(1):71-75
DOI 10.1590/S0100-72032004000100011
PURPOSE: to determine daily calcium ingestion and its correlation with bone density in patients with anorexia nervosa. PATIENTS AND METHODS: fourteen women with anorexia nervosa recorded their 24 h food ingestion in a standardized diary and were submitted to bone densitometry. Data were analyzed statistically by the c² test and the Pearson correlation, with the level of significance set at p<0.05. RESULTS: mean bone density in the lumbar spine and in the femur were 0.95 ± 0.15 and 0.88 ± 0.26, respectively. There was a significant correlation between time of amenorrhea and bone mass loss both in the lumbar spine (r=-0.65; p=0.01) and in the femur (r=-0.71; p=0.006). All patients but one presented lower calcium ingestion than the recommended dietary allowances, with a mean of 554.5 mg/day (range from 120 to 840 mg/day). Sixty-four percent of the patients presented some degree of bone mass loss (osteopenia or osteoporosis) in the spine and 57% in the femur. None of the six patients with a deficit in calcium ingestion of less than 60% presented osteoporosis; on the other hand, three of eight patients who had deficit in calcium ingestion higher than 60% presented osteoporosis. CONCLUSION: patients with anorexia nervosa had a low calcium ingestion and a significant bone mass loss, which were directly intercorrelated. Low bone density was also correlated with time of amenorrhea.
Summary
Rev Bras Ginecol Obstet. 2004;26(1):71-75
DOI 10.1590/S0100-72032004000100011
PURPOSE: to determine daily calcium ingestion and its correlation with bone density in patients with anorexia nervosa. PATIENTS AND METHODS: fourteen women with anorexia nervosa recorded their 24 h food ingestion in a standardized diary and were submitted to bone densitometry. Data were analyzed statistically by the c² test and the Pearson correlation, with the level of significance set at p<0.05. RESULTS: mean bone density in the lumbar spine and in the femur were 0.95 ± 0.15 and 0.88 ± 0.26, respectively. There was a significant correlation between time of amenorrhea and bone mass loss both in the lumbar spine (r=-0.65; p=0.01) and in the femur (r=-0.71; p=0.006). All patients but one presented lower calcium ingestion than the recommended dietary allowances, with a mean of 554.5 mg/day (range from 120 to 840 mg/day). Sixty-four percent of the patients presented some degree of bone mass loss (osteopenia or osteoporosis) in the spine and 57% in the femur. None of the six patients with a deficit in calcium ingestion of less than 60% presented osteoporosis; on the other hand, three of eight patients who had deficit in calcium ingestion higher than 60% presented osteoporosis. CONCLUSION: patients with anorexia nervosa had a low calcium ingestion and a significant bone mass loss, which were directly intercorrelated. Low bone density was also correlated with time of amenorrhea.
Summary
Rev Bras Ginecol Obstet. 2003;25(7):507-512
DOI 10.1590/S0100-72032003000700007
PURPOSE: to evaluate the prevalence of osteoporosis in climacteric women and analyze the influence of general and reproductive risk factors on bone mineral density. METHODS: a cross-sectional study with the evaluation of the 473 hospital records of climacteric women followed up at the Menopause Outpatient Facility of CAISM/Unicamp, between 03/28/2000 and 04/17/2001. These women were at least 12 months in amenorrhea and presented the results of a bone densitometry study performed at the Nuclear Medicine Department of HC/Unicamp. The following variables were evaluated: age, color, body mass index, level of education, smoking, use of medication, age at menopause, parity, use and length of hormone replacement therapy and its effect on bone mineral density. Statistical analyses were performed using logistic regression ajusted by age and hormone replacement therapy use. RESULTS: the mean age of the studied women was 53.9 years (± 7.1 SD) with mean age at menopause being 45.9 years (± 6.9 SD). Osteoporosis occurred in 14.7% and osteopenia in 38% of the cases in the lumbar vertebrae (L2-L4 interspace) and in 3.8 and 32.7% in the femur, respectively. Logistic regression adjusted to age and hormone therapy showed an association between the following variables: level of education, age at menopause and body mass index. CONCLUSION: there was a high prevalence of osteoporosis and osteopenia in the studied population. Advanced age, lower level of education, late menarche, early menopause and lower body mass index were identified as risk factors for developing decreased bone mass in the studied population.
Summary
Rev Bras Ginecol Obstet. 2003;25(7):507-512
DOI 10.1590/S0100-72032003000700007
PURPOSE: to evaluate the prevalence of osteoporosis in climacteric women and analyze the influence of general and reproductive risk factors on bone mineral density. METHODS: a cross-sectional study with the evaluation of the 473 hospital records of climacteric women followed up at the Menopause Outpatient Facility of CAISM/Unicamp, between 03/28/2000 and 04/17/2001. These women were at least 12 months in amenorrhea and presented the results of a bone densitometry study performed at the Nuclear Medicine Department of HC/Unicamp. The following variables were evaluated: age, color, body mass index, level of education, smoking, use of medication, age at menopause, parity, use and length of hormone replacement therapy and its effect on bone mineral density. Statistical analyses were performed using logistic regression ajusted by age and hormone replacement therapy use. RESULTS: the mean age of the studied women was 53.9 years (± 7.1 SD) with mean age at menopause being 45.9 years (± 6.9 SD). Osteoporosis occurred in 14.7% and osteopenia in 38% of the cases in the lumbar vertebrae (L2-L4 interspace) and in 3.8 and 32.7% in the femur, respectively. Logistic regression adjusted to age and hormone therapy showed an association between the following variables: level of education, age at menopause and body mass index. CONCLUSION: there was a high prevalence of osteoporosis and osteopenia in the studied population. Advanced age, lower level of education, late menarche, early menopause and lower body mass index were identified as risk factors for developing decreased bone mass in the studied population.
Summary
Rev Bras Ginecol Obstet. 2000;22(8):475-479
DOI 10.1590/S0100-72032000000800002
Purpose: to evaluate the bone mineral density of postmenopausal women with previous hysterectomy and with bilateral ovarian conservation compared to a group of nonhysterectomized naturally menopausal women. Methods: this is a cross-sectional study of bone densitometry (Lunar DPX) in 30 menopausal women hysterectomized when in the premenopause compared with 102 naturally postmenopausal women. Results: the mean age, body mass index, color of the skin, smoking habits, educational level, menarche, parity and previous tubal ligation were similar in the studied groups. Bone mineral density average and the T-score of the three femural sites analyzed by the Bonferroni test did not show significant differences. The bone mineral density average and the T-score of the lumbar spine were analyzed by the Student t test and did not show statistical differences. Conclusion: these findings suggest that premenopausal hysterectomy with bilateral ovarian conservation does not cause an additional reduction in bone mineral content when evaluated in the postmenopause.
Summary
Rev Bras Ginecol Obstet. 2000;22(8):475-479
DOI 10.1590/S0100-72032000000800002
Purpose: to evaluate the bone mineral density of postmenopausal women with previous hysterectomy and with bilateral ovarian conservation compared to a group of nonhysterectomized naturally menopausal women. Methods: this is a cross-sectional study of bone densitometry (Lunar DPX) in 30 menopausal women hysterectomized when in the premenopause compared with 102 naturally postmenopausal women. Results: the mean age, body mass index, color of the skin, smoking habits, educational level, menarche, parity and previous tubal ligation were similar in the studied groups. Bone mineral density average and the T-score of the three femural sites analyzed by the Bonferroni test did not show significant differences. The bone mineral density average and the T-score of the lumbar spine were analyzed by the Student t test and did not show statistical differences. Conclusion: these findings suggest that premenopausal hysterectomy with bilateral ovarian conservation does not cause an additional reduction in bone mineral content when evaluated in the postmenopause.
Summary
Rev Bras Ginecol Obstet. 2001;23(10):621-626
DOI 10.1590/S0100-72032001001000002
Purpose: to compare bone mineral density (BMD) of postmenopausal women with and without the antecedent of tubal ligation, as well as to evaluate the associated factors that affect the bone mineral density of femur and lumbar spine of both groups. Methods: 70 postmenopausal women in each group were analyzed at CAISM-UNICAMP, during the year of 1998. All women answered a questionnaire about some clinical and reproductive characteristics and underwent bone densitometry (Lunar DPX) to measure bone mineral density of the femur and lumbar spine. Statistical analyses were performed using Student's t-test, Fisher`s exact test, Pearson c² test, Bonferroni`s test and multiple regression analysis. Results: mean age of patients was 53.2 years and for controls it was 52.6 years. Mean age of 48 years at menopause was similar in both groups. Mean age at tubal ligation surgery was 33.7 years and time since surgery was 18 years. The multiple comparison of the average bone mineral density of femur and lumbar spine did not show statistical differences between the groups. The percentage distribution of the T-score categories of femur and lumbar spine, classified into normal and altered, also did not show statistical differences between both groups. Multiple regression analysis showed that bone mineral density of femur was directly associated with body mass index, but age was indirectly associated. The variables dark skin, parity, age at menopause, educational level and body mass index were directly associated with bone mineral density of lumbar spine, but age at menarche was inversely associated. Conclusion: these findings suggest that tubal ligation does not seem to cause an additional reduction in bone mineral density when evaluated in postmenopause.
Summary
Rev Bras Ginecol Obstet. 2001;23(10):621-626
DOI 10.1590/S0100-72032001001000002
Purpose: to compare bone mineral density (BMD) of postmenopausal women with and without the antecedent of tubal ligation, as well as to evaluate the associated factors that affect the bone mineral density of femur and lumbar spine of both groups. Methods: 70 postmenopausal women in each group were analyzed at CAISM-UNICAMP, during the year of 1998. All women answered a questionnaire about some clinical and reproductive characteristics and underwent bone densitometry (Lunar DPX) to measure bone mineral density of the femur and lumbar spine. Statistical analyses were performed using Student's t-test, Fisher`s exact test, Pearson c² test, Bonferroni`s test and multiple regression analysis. Results: mean age of patients was 53.2 years and for controls it was 52.6 years. Mean age of 48 years at menopause was similar in both groups. Mean age at tubal ligation surgery was 33.7 years and time since surgery was 18 years. The multiple comparison of the average bone mineral density of femur and lumbar spine did not show statistical differences between the groups. The percentage distribution of the T-score categories of femur and lumbar spine, classified into normal and altered, also did not show statistical differences between both groups. Multiple regression analysis showed that bone mineral density of femur was directly associated with body mass index, but age was indirectly associated. The variables dark skin, parity, age at menopause, educational level and body mass index were directly associated with bone mineral density of lumbar spine, but age at menarche was inversely associated. Conclusion: these findings suggest that tubal ligation does not seem to cause an additional reduction in bone mineral density when evaluated in postmenopause.