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Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(4):255-260
DOI 10.1590/S0100-72032003000400006
PURPOSE: to compare maternal morbidity, neonatal results and some clinical and epidemiological characteristics among primiparous women who had one previous cesarean section, according to the performance of elective cesarean (EC) section or trial of labor (TL) during the second delivery. PATIENTS AND METHODS: this is a retrospective cross-sectional study on the second delivery of women who previously had a cesarean section and were assisted at the Center for Integral Assistance to Women's Health (CAISM/UNICAMP), from 1986 to 1998. Data were collected from 2068 clinical records corresponding to 322 cases of EC and 1746 of TL. Data analysis was performed through percentage distribution of the EC and TL cases and also the distribution of variables between these two groups, using the chi2, chi2 for trend and Fisher exact tests to evaluate the statistical difference, with a significance level of 95%. RESULTS: the indication of EC decreased progressively with time, from 22.6% in 1986 to 5% in 1998. Maternal morbity was similar and low in both groups (1.24% and 1.21%). There was no significant difference between groups regarding Apgar score and stillbirths, but there was a significantly higher proportion of premature newborns and with birth weight below 2.500 g and above 4.000 g in the group who underwent EC. The prevalence of EC was significantly higher in women 35 or more years old, with previous or current history of hypertensive disorder, diabetes or with a first dead child, as well as with changes in the volume of amniotic fluid. CONCLUSIONS: performing TL progressively increased during this period of thirteen years, without any increase of maternal and/or neonatal morbidity. The indication for EC followed medical criteria related to unfavorable maternal and/or fetal clinical conditions for vaginal delivery.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(4):255-260
DOI 10.1590/S0100-72032003000400006
PURPOSE: to compare maternal morbidity, neonatal results and some clinical and epidemiological characteristics among primiparous women who had one previous cesarean section, according to the performance of elective cesarean (EC) section or trial of labor (TL) during the second delivery. PATIENTS AND METHODS: this is a retrospective cross-sectional study on the second delivery of women who previously had a cesarean section and were assisted at the Center for Integral Assistance to Women's Health (CAISM/UNICAMP), from 1986 to 1998. Data were collected from 2068 clinical records corresponding to 322 cases of EC and 1746 of TL. Data analysis was performed through percentage distribution of the EC and TL cases and also the distribution of variables between these two groups, using the chi2, chi2 for trend and Fisher exact tests to evaluate the statistical difference, with a significance level of 95%. RESULTS: the indication of EC decreased progressively with time, from 22.6% in 1986 to 5% in 1998. Maternal morbity was similar and low in both groups (1.24% and 1.21%). There was no significant difference between groups regarding Apgar score and stillbirths, but there was a significantly higher proportion of premature newborns and with birth weight below 2.500 g and above 4.000 g in the group who underwent EC. The prevalence of EC was significantly higher in women 35 or more years old, with previous or current history of hypertensive disorder, diabetes or with a first dead child, as well as with changes in the volume of amniotic fluid. CONCLUSIONS: performing TL progressively increased during this period of thirteen years, without any increase of maternal and/or neonatal morbidity. The indication for EC followed medical criteria related to unfavorable maternal and/or fetal clinical conditions for vaginal delivery.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(4):255-258
DOI 10.1590/S0100-72032001000400009
We report a malignant case of breast neoplasm, with the diagnosis of leiomyosarcoma. This rare neoplasm has a less aggressive biological behavior than the other types of breast sarcomas. That is the reason why we emphasize the correct diagnosis, and the necessity of graduating the neoplasm, for the patient's best follow-up. In our case, after 2 years of follow-up the patient continued with no relapse of the disease.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(4):255-258
DOI 10.1590/S0100-72032001000400009
We report a malignant case of breast neoplasm, with the diagnosis of leiomyosarcoma. This rare neoplasm has a less aggressive biological behavior than the other types of breast sarcomas. That is the reason why we emphasize the correct diagnosis, and the necessity of graduating the neoplasm, for the patient's best follow-up. In our case, after 2 years of follow-up the patient continued with no relapse of the disease.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(6):255-257
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(6):255-257
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(4):256-263
The hypothesis of fetal origins to adult diseases proposes that metabolic chronic disorders, including cardiovascular diseases, diabetes, and hypertension originate in the developmental plasticity due to intrauterine insults. These processes involve an adaptative response by the fetus to changes in the environmental signals, which can promote the reset of hormones and of the metabolism to establish a “thrifty phenotype”. Metabolic alterations during intrauterine growth restriction can modify the fetal programming. The present nonsystematic review intended to summarize historical and current references that indicated that developmental origins of health and disease (DOHaD) occur as a consequence of altered maternal and fetal metabolic pathways. The purpose is to highlight the potential implications of growth factors and adipokines in “developmental programming”, which could interfere in the development by controlling fetal growth patterns. These changes affect the structure and the functional capacity of various organs, including the brain, the kidneys, and the pancreas. These investigations may improve the approach to optimizing antenatal as well as perinatal care aimed to protect newborns against long-termchronic diseases.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(4):256-263
The hypothesis of fetal origins to adult diseases proposes that metabolic chronic disorders, including cardiovascular diseases, diabetes, and hypertension originate in the developmental plasticity due to intrauterine insults. These processes involve an adaptative response by the fetus to changes in the environmental signals, which can promote the reset of hormones and of the metabolism to establish a “thrifty phenotype”. Metabolic alterations during intrauterine growth restriction can modify the fetal programming. The present nonsystematic review intended to summarize historical and current references that indicated that developmental origins of health and disease (DOHaD) occur as a consequence of altered maternal and fetal metabolic pathways. The purpose is to highlight the potential implications of growth factors and adipokines in “developmental programming”, which could interfere in the development by controlling fetal growth patterns. These changes affect the structure and the functional capacity of various organs, including the brain, the kidneys, and the pancreas. These investigations may improve the approach to optimizing antenatal as well as perinatal care aimed to protect newborns against long-termchronic diseases.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(3):256-256
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(3):256-256
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(3):256-256
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(3):256-256
, , Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(4):256-263
, , To investigate the association between prenatal care (PNC) adequacy indexes and the low birth weigth (LBW) outcome.
A total of 368,093 live term singleton births in the state of Rio de Janeiro (Brazil) from 2015 to 2016 were investigated using data from the Brazilian Live Birth Information System (Sistema de Informações sobre Nascidos Vivos, SINASC, in Portuguese). Seven PNC adequacy indexes were evaluated: four developed by Brazilian authors (Ciari Jr. et al., Coutinho et al., Takeda, and an index developed and used by the Brazilian Ministry of Health - MS) and three by authors from other countries (Kessner et al., the Adequacy of Prenatal Care Utilization index - APNCU, and the Graduated Prenatal Care Utilization Index - GINDEX). Adjusted odds ratios were estimated for the PNC adequacy indexes by means of multivariate logistic regression models using maternal, gestational and newborn characteristics as covariates.
When the PNC is classified as “inadequate”, the adjusted odds ratios to the LBWoutcome increase between 42% and 132%, depending on which adequacy index is evaluated. Younger (15 to 17 years old) and older (35 to 45 years old) mothers, those not married, of black or brown ethnicity, with low schooling (who did not finish Elementary School), primiparous, with preterm births, as well as female newborns had increasing odds for LBW. The models presented areas under the receiver operating characteristic (ROC) curve between 80.4% and 81.0%, and sensitivity and specificity that varied, respectively, between 57.7% and 58.6% and 94.3% and 94.5%.
Considering all PNC adequacy indexes evaluated, the APNCU had the best discriminatory power and the best ability to predict the LBW outcome.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(4):256-263
, , To investigate the association between prenatal care (PNC) adequacy indexes and the low birth weigth (LBW) outcome.
A total of 368,093 live term singleton births in the state of Rio de Janeiro (Brazil) from 2015 to 2016 were investigated using data from the Brazilian Live Birth Information System (Sistema de Informações sobre Nascidos Vivos, SINASC, in Portuguese). Seven PNC adequacy indexes were evaluated: four developed by Brazilian authors (Ciari Jr. et al., Coutinho et al., Takeda, and an index developed and used by the Brazilian Ministry of Health - MS) and three by authors from other countries (Kessner et al., the Adequacy of Prenatal Care Utilization index - APNCU, and the Graduated Prenatal Care Utilization Index - GINDEX). Adjusted odds ratios were estimated for the PNC adequacy indexes by means of multivariate logistic regression models using maternal, gestational and newborn characteristics as covariates.
When the PNC is classified as “inadequate”, the adjusted odds ratios to the LBWoutcome increase between 42% and 132%, depending on which adequacy index is evaluated. Younger (15 to 17 years old) and older (35 to 45 years old) mothers, those not married, of black or brown ethnicity, with low schooling (who did not finish Elementary School), primiparous, with preterm births, as well as female newborns had increasing odds for LBW. The models presented areas under the receiver operating characteristic (ROC) curve between 80.4% and 81.0%, and sensitivity and specificity that varied, respectively, between 57.7% and 58.6% and 94.3% and 94.5%.
Considering all PNC adequacy indexes evaluated, the APNCU had the best discriminatory power and the best ability to predict the LBW outcome.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(5):256-256
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(5):256-256