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Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(10):588-593
DOI 10.1590/S0100-72032005001000004
PURPOSE: to evaluate the prevalence of intrauterine adhesions after manual vacuum aspiration for the treatment of abortion. METHODS: a prospective, descriptive study, with group comparison was carried out between November 2000 and August 2001 on 80 women between 15 and 48 years old, admitted to a public hospital for abortion care. Manual vacuum aspiration consisted of extracting the uterine content by suction using a Karman syringe connected to plastic cannulas. Intrauterine adhesions were screened by hysteroscopy, performed 40-60 days after the aspiration. Statistical analysis was performed using Fisher exact test, ANOVA and estimation of prevalence risk, when indicated. RESULTS: hysteroscopy identified intrauterine adhesions in 13 patients (prevalence = 16.3%), most of them of the mucosal type (9 of 13), minimal severity (11 of 13) and lateral location in the uterus (5 of 13). Adhesions were more frequent at a gestational age more than 8 weeks (24.4 vs 3.7%; prevalence risk of 6.6) as well as in missed abortion (41.7 vs 12.1% ; prevalence risk of 3.54). CONCLUSIONS: prevalence of intrauterine adhesions after manual vacuum aspiration was 16.3%. Missed abortion and advanced gestational age seem to be associated with the occurrence of adhesions.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(10):588-593
DOI 10.1590/S0100-72032005001000004
PURPOSE: to evaluate the prevalence of intrauterine adhesions after manual vacuum aspiration for the treatment of abortion. METHODS: a prospective, descriptive study, with group comparison was carried out between November 2000 and August 2001 on 80 women between 15 and 48 years old, admitted to a public hospital for abortion care. Manual vacuum aspiration consisted of extracting the uterine content by suction using a Karman syringe connected to plastic cannulas. Intrauterine adhesions were screened by hysteroscopy, performed 40-60 days after the aspiration. Statistical analysis was performed using Fisher exact test, ANOVA and estimation of prevalence risk, when indicated. RESULTS: hysteroscopy identified intrauterine adhesions in 13 patients (prevalence = 16.3%), most of them of the mucosal type (9 of 13), minimal severity (11 of 13) and lateral location in the uterus (5 of 13). Adhesions were more frequent at a gestational age more than 8 weeks (24.4 vs 3.7%; prevalence risk of 6.6) as well as in missed abortion (41.7 vs 12.1% ; prevalence risk of 3.54). CONCLUSIONS: prevalence of intrauterine adhesions after manual vacuum aspiration was 16.3%. Missed abortion and advanced gestational age seem to be associated with the occurrence of adhesions.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(2):51-57
DOI 10.1590/S0100-72032005000200002
PURPOSE: to estimate the validity of visual inspection of cervical intraepithelial neoplasia (CIN) and HPV-induced lesion screening, after acetic acid application (VIA), and to compare its performance with that of colpocytology and colposcopy. METHODS: a diagnostic test validation study involving 893 women aged 18 to 65 years, simultaneously screened with colpocytology, VIA and colposcopy was carried out at a public health unit in Recife, PE. VIA was performed by applying 5% acetic acid onto the cervix and observing it with the help of a clinical spotlight. The finding of any aceto-white lesion on the cervix was considered positive. The gold standard was the histopathology of cervical biopsy, carried out whenever any of the three test results was abnormal. Validity indicators were estimated for each test, within 95% confidence intervals. The analysis of agreement between test results was done by the kappa coefficient. RESULTS: of 303 women submitted to biopsy, the histopathological study was abnormal in 24. Among this total, VIA was positive in 22, yielding an estimated 91.7% sensibility, 68.9% specificity, and 7.5% positive predictive value and 99.7% negative predictive value. Comparing 95% confidence intervals, VIA was more sensitive than colpocytology, despite a lower specificity and positive predictive value. There was poor agreement between VIA and colpocytology (k=0.02) and excellent agreement with colposcopy (k=0.93). CONCLUSION: VIA was much more sensitive than colpocytology in the screening of CIN and HPV-induced lesions and presented a performance similar to colposcopy. Its low specificity determined a high number of false-positive results.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(2):51-57
DOI 10.1590/S0100-72032005000200002
PURPOSE: to estimate the validity of visual inspection of cervical intraepithelial neoplasia (CIN) and HPV-induced lesion screening, after acetic acid application (VIA), and to compare its performance with that of colpocytology and colposcopy. METHODS: a diagnostic test validation study involving 893 women aged 18 to 65 years, simultaneously screened with colpocytology, VIA and colposcopy was carried out at a public health unit in Recife, PE. VIA was performed by applying 5% acetic acid onto the cervix and observing it with the help of a clinical spotlight. The finding of any aceto-white lesion on the cervix was considered positive. The gold standard was the histopathology of cervical biopsy, carried out whenever any of the three test results was abnormal. Validity indicators were estimated for each test, within 95% confidence intervals. The analysis of agreement between test results was done by the kappa coefficient. RESULTS: of 303 women submitted to biopsy, the histopathological study was abnormal in 24. Among this total, VIA was positive in 22, yielding an estimated 91.7% sensibility, 68.9% specificity, and 7.5% positive predictive value and 99.7% negative predictive value. Comparing 95% confidence intervals, VIA was more sensitive than colpocytology, despite a lower specificity and positive predictive value. There was poor agreement between VIA and colpocytology (k=0.02) and excellent agreement with colposcopy (k=0.93). CONCLUSION: VIA was much more sensitive than colpocytology in the screening of CIN and HPV-induced lesions and presented a performance similar to colposcopy. Its low specificity determined a high number of false-positive results.