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  • Original Article

    Modulation by progesterone of pain sensitivity to mechanical and ischemic stimuli in young and healthy women

    Rev Bras Ginecol Obstet. 2008;30(6):306-311

    Summary

    Original Article

    Modulation by progesterone of pain sensitivity to mechanical and ischemic stimuli in young and healthy women

    Rev Bras Ginecol Obstet. 2008;30(6):306-311

    DOI 10.1590/S0100-72032008000600007

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    PURPOSE: to investigate the relationship between pain perception (experimental pain threshold and tolerance, in response to ischemia and pressure) in young and healthy young women and female sexual hormone seric levels (estradiol and progesterone). METHODS: 18 volunteers have participated of this study, during three consecutive menstrual cycles. A pressure algometer and a manual dynamometer have been used to measure painful responses to pressure and ischemia algesic stimuli. Blood has been collected for assessment of both hormonal and painful variables, during three menstrual cycles, whose characterization was based on daily oral temperature record, a diary of the menstrual cycles with the onset and end of each cycle, and on estradiol and progesterone plasmatic levels. The average for the algesic variables measured has been compared by analysis of variance (ANOVA) and the Tukey-Kramer's post-test, among the menstrual cycle phases (follicular, periovulatory, early luteal, late luteal and menstrual). The Pearson's test has been used for correlation analysis between algesic and hormonal variables. Statistical significance has been defined as p<0.05. RESULTS: no significant change in pain parameters among the menstrual cycle phases has been observed. Nevertheless, there have been significant negative correlations between progesterone and ischemic threshold (r=-0.23; p<0.01), and pressure tolerance (r=-0.23; p<0.01) at the early luteal phase. CONCLUSIONS: these results indicate that the increase in progesterone levels correlates with a decrease of ischemic threshold and pressure tolerance, suggesting that progesterone plays a role in the pain modulation during the early luteal phase.

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    Modulation by progesterone of pain sensitivity to mechanical and ischemic stimuli in young and healthy women
  • Original Article

    Sexual dysfunction in obese women is more affected by psychological domains than that of non-obese

    Rev Bras Ginecol Obstet. 2015;37(12):552-558

    Summary

    Original Article

    Sexual dysfunction in obese women is more affected by psychological domains than that of non-obese

    Rev Bras Ginecol Obstet. 2015;37(12):552-558

    DOI 10.1590/SO100-720320155443

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    Abstract

    PURPOSE:

    To compare differences in the occurrence and changed domains of sexual dysfunction in obese and non-obese Brazilian women.

    METHODS:

    Female Sexual Function Index, based on six domains, to investigate 31 sexual dysfunction incidence for obese compared to 32 non-obese women, was used. Statistical analysis using ANOVA and MANOVA were performed to compare total scores of Female Sexual Function Index among groups and to identify the differences among domains, Student t -test was used. Statistical significant level was established for all tests for p<0.05.

    RESULTS:

    No difference in female sexual dysfunction frequency between obese (25.8%) and non-obese women (22.5%) was found. However, an important distinction in which aspects of sexual life were affected was found. While the obese group was impaired in three domains of sexual life (desire, orgasm, and arousal), in the control group five aspects were dysfunctional (desire, orgasm, arousal, pain and lubrication). Future research exploring psychological outcomes in obese females, such as body image and measures of positive and negative effect, might better characterize the female sexual dysfunction in this group.

    CONCLUSIONS:

    Obesity does not appear to be an independent factor for allow quality of female sexual life. However, disturbance associated to obesity indicates a low frequency of disorder in physical domains, suggesting that psychological factors seem to be mainly involved in the sexual dysfunction in obese women.

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