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Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(11):834-839
, , , It has been suggested that excess body weight could represent a risk factor for infertility outcomes. The present study aimed to evaluate the association of overweight and anovulation among infertile women with regular menstrual cycles.
We conducted a retrospective case-control study with consistently anovulatory patients undergoing assisted reproduction treatment. The patients were stratified into normal weight (body mass index [BMI]: 18.5-24.9kg/m2) and overweight (BMI: 25.0- 29.9kg/m2).Those with polycystic ovary syndrome or obesity were excluded. The groups were matched for age, duration of infertility, prolactin, follicle stimulating hormone (FSH), thydroid stimulating hormone (TSH), luteinizing hormone (LH), and estradiol levels.
Overweight was significantly associated with anovulation, when using the World Health Organization (WHO) criteria for anovulation: progesterone levels>5.65 ng/ml and ultrasonography evidence of follicle collapse (odds ratio [OR]: 2.69; 95% confidence interval [CI95%]: 1.04-6.98).
Body mass index above the normal range jeopardizes ovulation among non-obese infertile women with regular menstrual cycles.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(11):834-839
, , , It has been suggested that excess body weight could represent a risk factor for infertility outcomes. The present study aimed to evaluate the association of overweight and anovulation among infertile women with regular menstrual cycles.
We conducted a retrospective case-control study with consistently anovulatory patients undergoing assisted reproduction treatment. The patients were stratified into normal weight (body mass index [BMI]: 18.5-24.9kg/m2) and overweight (BMI: 25.0- 29.9kg/m2).Those with polycystic ovary syndrome or obesity were excluded. The groups were matched for age, duration of infertility, prolactin, follicle stimulating hormone (FSH), thydroid stimulating hormone (TSH), luteinizing hormone (LH), and estradiol levels.
Overweight was significantly associated with anovulation, when using the World Health Organization (WHO) criteria for anovulation: progesterone levels>5.65 ng/ml and ultrasonography evidence of follicle collapse (odds ratio [OR]: 2.69; 95% confidence interval [CI95%]: 1.04-6.98).
Body mass index above the normal range jeopardizes ovulation among non-obese infertile women with regular menstrual cycles.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(10):625-630
Improving infrastructural conditions of the in vitro fertilization laboratory, such as the air quality, has profound positive effects on embryo culture. Poor environmental conditions reduce the rate of embryo formation and, therefore, of pregnancy. This review article presents important publications regarding the impact of air quality in human reproduction laboratories on embryo quality, pregnancy success, and live births. The studies demonstrate that the replacing the air filtration system improves significantly the environmental air quality, and, consequently, improves laboratory parameters, such as the fertilization rate, the number of blastocysts, the embryo implantation rate, and the number of live births. On the other hand, improving air quality decreases the number of abortions. Therefore, environmental parameters that improve embryo quality and increase healthy child birth ratesmust be themain targets for the assisted reproduction laboratory quality control.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(10):625-630
Improving infrastructural conditions of the in vitro fertilization laboratory, such as the air quality, has profound positive effects on embryo culture. Poor environmental conditions reduce the rate of embryo formation and, therefore, of pregnancy. This review article presents important publications regarding the impact of air quality in human reproduction laboratories on embryo quality, pregnancy success, and live births. The studies demonstrate that the replacing the air filtration system improves significantly the environmental air quality, and, consequently, improves laboratory parameters, such as the fertilization rate, the number of blastocysts, the embryo implantation rate, and the number of live births. On the other hand, improving air quality decreases the number of abortions. Therefore, environmental parameters that improve embryo quality and increase healthy child birth ratesmust be themain targets for the assisted reproduction laboratory quality control.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(10):647-651
DOI 10.1590/S0100-72032000001000008
Purpose: to study the effects of ciprofloxacin on abortion percentage, maternal weight gain during pregnancy, fetal and maternal death, gross fetal malformation, newborn number, weight and neurological reflexes. Methods: we used 30 Wistar rats, divided into three groups: D50-treated (ciprofloxacin, 50 mg/kg); D100-treated (ciprofloxacin 100 mg/kg) and control group which received physiological saline per os, from the 1st to the 7th day after mating. We studied abortion percentage, maternal weight gain during pregnancy, fetal and maternal death, gross fetal malformation, newborn number and weight at 1st, 3rd, 5th and 10th day of life and newborn neurological reflexes at 1st, 3rd, 5th and 10th day of life. Results: there was no difference between groups in the number of rats that became pregnant. The same was found for maternal weight gain and newborn number. There was a difference in newborn mean weight on day 3rd, 5th and 10th (p = 0.006, 0.01 and 0.03, respectively). The D100 newborn group was the one with less weight gain up to the 10th day of life. We found a significant difference (p = 0.002) in the newborn orientation reflex on the 1st day of life, that disappeared afterwards. No abortion or gross malformation was found in this study. Conclusions: ciprofloxacin modified the newborn weight and reflex on the first days of life. In conclusion, we consider that the use of ciprofloxacin should be restricted during the pregnancy.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(10):647-651
DOI 10.1590/S0100-72032000001000008
Purpose: to study the effects of ciprofloxacin on abortion percentage, maternal weight gain during pregnancy, fetal and maternal death, gross fetal malformation, newborn number, weight and neurological reflexes. Methods: we used 30 Wistar rats, divided into three groups: D50-treated (ciprofloxacin, 50 mg/kg); D100-treated (ciprofloxacin 100 mg/kg) and control group which received physiological saline per os, from the 1st to the 7th day after mating. We studied abortion percentage, maternal weight gain during pregnancy, fetal and maternal death, gross fetal malformation, newborn number and weight at 1st, 3rd, 5th and 10th day of life and newborn neurological reflexes at 1st, 3rd, 5th and 10th day of life. Results: there was no difference between groups in the number of rats that became pregnant. The same was found for maternal weight gain and newborn number. There was a difference in newborn mean weight on day 3rd, 5th and 10th (p = 0.006, 0.01 and 0.03, respectively). The D100 newborn group was the one with less weight gain up to the 10th day of life. We found a significant difference (p = 0.002) in the newborn orientation reflex on the 1st day of life, that disappeared afterwards. No abortion or gross malformation was found in this study. Conclusions: ciprofloxacin modified the newborn weight and reflex on the first days of life. In conclusion, we consider that the use of ciprofloxacin should be restricted during the pregnancy.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(7):459-462
DOI 10.1590/S0100-72032001000700008
Purpose: to compare the performance in tests between students with and without premenstrual syndrome (PMS), and between students with PMS in and outside the premenstrual period. Methods: the present study had a before-after design (quasi-experimental), to which 40 control patients without PMS were added. A total of 40 students from high school and courses for admission to the University were evaluated using, a standardized questionnaire. The students were divided, according to the scores obtained, into three groups: A) PMS group in the premenstrual period; B) PMS group outside the premenstrual period; C) control group (no PMS). The marks obtained in Physics and Math tests by the groups with and without PMS were analyzed by the Mann-Whitney test. The marks of the group PMS in and outside the premenstrual period were evaluated by the signal test. Results: of 4438 questionnaires applied, 29 from students with PMS and 29 from controls were selected. Comparing the medians of the marks obtained by the students from the PMS group in and outside the premenstrual period, there was no significant difference. There was also no significant difference between the marks of the PMS and control groups. Also, when the scores were evaluated, there was no difference in and outside the period, in the PMS group. Conclusion: PMS was not able to modify significantly the students' marks or scores in this study.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(7):459-462
DOI 10.1590/S0100-72032001000700008
Purpose: to compare the performance in tests between students with and without premenstrual syndrome (PMS), and between students with PMS in and outside the premenstrual period. Methods: the present study had a before-after design (quasi-experimental), to which 40 control patients without PMS were added. A total of 40 students from high school and courses for admission to the University were evaluated using, a standardized questionnaire. The students were divided, according to the scores obtained, into three groups: A) PMS group in the premenstrual period; B) PMS group outside the premenstrual period; C) control group (no PMS). The marks obtained in Physics and Math tests by the groups with and without PMS were analyzed by the Mann-Whitney test. The marks of the group PMS in and outside the premenstrual period were evaluated by the signal test. Results: of 4438 questionnaires applied, 29 from students with PMS and 29 from controls were selected. Comparing the medians of the marks obtained by the students from the PMS group in and outside the premenstrual period, there was no significant difference. There was also no significant difference between the marks of the PMS and control groups. Also, when the scores were evaluated, there was no difference in and outside the period, in the PMS group. Conclusion: PMS was not able to modify significantly the students' marks or scores in this study.
