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9 articles
  • Editorial

    Syphilis in Pregnancy and Congenital Syphilis: Why Can We not yet Face This Problem?

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):425-427

    Summary

    Editorial

    Syphilis in Pregnancy and Congenital Syphilis: Why Can We not yet Face This Problem?

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):425-427

    DOI 10.1055/s-0036-1593603

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    The increased occurrence of syphilis during pregnancy, and its severe repercussions to the fetal environment, has been a cause for concern among health care professionals. It is hard to comprehend why congenital syphilis has not yet been controlled, since its agent, the spirochaete Treponema pallidum, is well known and is highly susceptible to penicillin, a […]
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  • Original Article

    Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):428-435

    Summary

    Original Article

    Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):428-435

    DOI 10.1055/s-0036-1593410

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    Abstract

    Objectives

    This study was done to evaluate the normal fetal cerebral lateral ventricle dimensions with transabdominal ultrasonography. The atrial width (AW), ventricle-tochoroid measurement (V-C), ventricle-to-hemisphere ratio (VHR), and combined anterior horn measurement (CAHM) were taken.

    Methods

    This was a cross-sectional study involving 400 normal singleton pregnant subjects whose gestational ages were between 14 and 40 weeks. Transabdominal sonography was performed to obtain the values of the fetal cerebral lateral ventricle (FCLV) parameters. Data were reported as mean standard deviation (SD) for continuous variables. The degrees of correlation between FCLV parameters and the estimated gestational age (EGA) were obtained using Pearson's correlation. Regression equations were used to generate the reference limits for the FCLV measurements.

    Results

    The values of AW, V-C measurements and CAHM increased with advancing gestation. The mean values of the AW, V-C and CAHM from 14 to 40 weeks increased from 6.60 0.94 mm to 9.75 0.07 mm (R2 = 0.114), 0.80 0.00 mm to 1.90 0.14 mm (R2= 0.266), and 6.95 0.06 mm to 23.07 4.02 mm (R2= 0.692) respectively, while the mean VHR decreased from 61.20 1.60% to 42.84 2.91% (R2 = 0.706) over the same period.

    Conclusion

    The AW, V-C, and CAHM increase, while VHR decreases with advancing gestation.

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    Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography
  • Original Article

    Neurological Outcome in Fetuses with Mild and Moderate Ventriculomegaly

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):436-442

    Summary

    Original Article

    Neurological Outcome in Fetuses with Mild and Moderate Ventriculomegaly

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):436-442

    DOI 10.1055/s-0036-1592315

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    Abstract

    Introduction

    Ventriculomegaly (VM) is one the most frequent anomalies detected on prenatal ultrasound. Magnetic resonance imaging (MRI) may enhance diagnostic accuracy and prediction of developmental outcome in newborns.

    Purpose

    The aim of this study was to assess the correlation between ultrasound and MRI in fetuses with isolated mild and moderate VM. The secondary aim was to report the neurodevelopmental outcome at 4 years of age.

    Methods

    Fetuses with a prenatal ultrasound (brain scan) diagnosis of VM were identified over a 4-year period. Ventriculomegaly was defined as an atrial width of 10- 15 mm that was further divided as mild (10.1-12.0 mm) and moderate (12.1-15.0 mm). Fetuses with VM underwent antenatal as well as postnatal follow-ups by brain scan and MRI. Neurodevelopmental outcome was performed using the Griffiths Mental Development Scales and conducted, where indicated, until 4 years into the postnatal period.

    Results

    Sixty-two fetuses were identified. Ventriculomegaly was bilateral in 58% of cases. A stable dilatation was seen in 45% of cases, progression was seen in 13%, and regression of VM was seen in 4.5% respectively. Fetal MRI was performed in 54 fetuses and was concordant with brain scan findings in 85% of cases. Abnormal neurodevelopmental outcomes were seen in 9.6% of cases.

    Conclusion

    Fetuses in whom a progression of VM is seen are at a higher risk of developing an abnormal neurodevelopmental outcome. Although brain scan and MRI are substantially in agreement in defining the grade of ventricular dilatation, a low correlation was seen in the evaluation of VM associated with central nervous system (CNS) or non-CNS abnormalities.

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    Neurological Outcome in Fetuses with Mild and Moderate Ventriculomegaly
  • Original Article

    Cultural Adaptation of the Patient Satisfaction Questionnaire and Validation of Its Use in the Portuguese Language for Women with Chronic Pelvic Pain

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):443-449

    Summary

    Original Article

    Cultural Adaptation of the Patient Satisfaction Questionnaire and Validation of Its Use in the Portuguese Language for Women with Chronic Pelvic Pain

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):443-449

    DOI 10.1055/s-0036-1592344

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    Abstract

    Objectives

    to translate and adapt the Patient Satisfaction Questionnaire (PSQ) to Portuguese and to assess its psychometric properties based on internal consistency, test-retest, factor analysis and divergent and convergent construct validities.

    Methods

    The study involved 218 participants and was approved by the local Research Ethics Committee. All participants gave written informed consent and their anonymity was ensured. The instrument was translated and culturally adapted for use in the Portuguese language. The internal consistency and factorial analysis were assessed by patients and physicians. Convergent and divergent validities were also assessed specifically for the patient group, as well as test-retest reliability. The Portuguese versions of the Patient Health Questionnaire (PHQ-9) and State-Trait Anxiety Inventory (STAI) were used for the analysis of the convergent validity. In addition, we applied a questionnaire of clinical and demographic data for the analysis of the divergent validity.

    Results

    The adapted version of the PSQ showed good Cronbach’s α and test-retest values, and the results of the convergent construct validity between the PSQ and the PHQ-9 (r = 0.34; p = 0.02) and the STAI (r = 0.47; p = 0.001) were negative, significant and moderate correlations. Divergent validity showed significant correlations only with race and education. The Brazilian Portuguese versionof the PSQ proved to be a valid and reliable instrument, with psychometric properties suitable for the assessment of satisfaction among patients with chronic pelvic pain and their physicians in Brazil. The questionnairemay allow the homogenization of reports on this topic in the international literature.

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    Cultural Adaptation of the Patient Satisfaction Questionnaire and Validation of Its Use in the Portuguese Language for Women with Chronic Pelvic Pain
  • Original Article

    Early Experience of Robotic Hysterectomy for Treatment of Benign Uterine Disease

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):450-455

    Summary

    Original Article

    Early Experience of Robotic Hysterectomy for Treatment of Benign Uterine Disease

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):450-455

    DOI 10.1055/s-0036-1592345

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    Abstract

    Objectives

    To demonstrate the initial experience of robotic hysterectomy to treat benign uterine disease at a university hospital in Brazil.

    Methods

    A cross-sectional study was conducted to review data from the first twenty patients undergoing robotic hysterectomy at our hospital. The surgeries were performed from November 2013 to August 2014, all of them by the same surgeon. The patients were reviewed for preoperative characteristics, including age, body mass index (BMI), indications for the hysterectomy and previous surgeries. Data of operative times, complications, postoperative pain and length of hospital stay were also collected.

    Results

    The total operating room time was 252.9 minutes, while the operative time was 180.7 minutes and the console time was 136.6 minutes. Docking time was 4.2 minutes, and the average undocking time was 1.9 minutes. There was a strong correlation between the operative time and the patient's BMI (r = 0.670 ; p = 0.001). The console time had significant correlation with the uterine weight and the patient's BMI (r = 0.468; p = 0.037). A learning curve was observed during docking and undocking times.

    Conclusion

    Despite its high cost, the robotic surgery is gaining more space in gynecological surgery. By the results obtained in our hospital, this surgical proposal proved to be feasible and safe. Our initial experience demonstrated a learning curve in some ways.

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    Early Experience of Robotic Hysterectomy for Treatment of Benign Uterine Disease
  • Original Article

    Creation of a Neovagina by Laparoscopic Modified Vecchietti Technique: Anatomic and Functional Results

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):456-464

    Summary

    Original Article

    Creation of a Neovagina by Laparoscopic Modified Vecchietti Technique: Anatomic and Functional Results

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):456-464

    DOI 10.1055/s-0036-1593775

    Views5

    Abstract

    Purpose

    To evaluate the anatomic and functional results of a laparoscopic modified Vecchietti technique for the creation of a neovagina in patients with congenital vaginal aplasia.

    Methods

    Retrospective study of nine patients with congenital vaginal aplasia submitted to the laparoscopic Vecchietti procedure, in our department, between 2006 and 2013. The anatomical results were evaluated by assessing the length, width and epithelialization of the neovagina at the postoperative visits. The functional outcome was evaluated using the Rosen Female Sexual Function Index (FSFI) questionnaire and comparing the patients' results to those of a control group of 20 healthy women. The statistical analysis was performed using SPSS Statistics version 19.0 (IBM, Armonk, NY, USA), Student t-test, Mann-Whitney U test and Fisher exact test.

    Results

    The condition underlying the vaginal aplasia was Mayer-Rokitansky-KüsterHauser syndrome in eight cases, and androgen insensitivity syndrome in one case. The average preoperative vaginal length was 2.9 cm. At surgery, the mean age of the patients was 22.2 years. The surgery was performed successfully in all patients and no intra or postoperative complications were recorded. At the first postoperative visit (6 to 8 weeks after surgery), the mean vaginal length was 8.1 cm. In all cases, the neovagina was epithelialized and had an appropriate width. The mean FSFI total and single domain scores did not differ significantly from those of the control group: 27.5 vs. 30.6 ( total); 4.0 vs. 4.2 (desire); 4.4 vs. 5.2 (arousal); 5.2 vs. 5.3 (lubrication); 4.2 vs. 5.0 ( orgasm); 5.3 vs. 5.5 (satisfaction) and 4.4 vs. 5.4 ( comfort ).

    Conclusions

    This modified laparoscopic Vecchietti technique is a simple, safe and effective procedure, which allows patients with congenital vaginal aplasia to have a satisfactory sexual activity, comparable to that of normal controls.

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    Creation of a Neovagina by Laparoscopic Modified Vecchietti Technique: Anatomic and Functional Results
  • Original Article

    Association between Number of Formed Embryos, Embryo Morphology and Clinical Pregnancy Rate after Intracytoplasmic Sperm Injection

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):465-470

    Summary

    Original Article

    Association between Number of Formed Embryos, Embryo Morphology and Clinical Pregnancy Rate after Intracytoplasmic Sperm Injection

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):465-470

    DOI 10.1055/s-0036-1592338

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    Abstract

    Introduction

    Infertility has a high prevalence in the general population, affecting 5 to 15% of couples in reproductive age. The assisted reproduction techniques ( ART ) include in vitro manipulation of gametes and embryos and are an important treatment indicated to these couples. It is well accepted that the implantation rate is positively influenced by the morphology of transferred embryos. However, we question if, apart from the assessment of embryo morphology, the number of produced embryos per cycle is also related to pregnancy rates in the first fresh transfer cycle.

    Purpose

    To evaluate the clinical pregnancy rate according to the number of formed embryos and the transfer of top quality embryos ( TQEs ).

    Methods

    In a retrospective cohort study, between January 2011 and December 2012 , we evaluated women who underwent intracytoplasmic sperm injection (ICSI), aged < 40 years, andwith at least 1 formed embryo fresh transferred in cleavagestage. These women were stratified into 3 groups according to the number of formed embryos (1 embryo, 2-3 and ≥ 4 embryos). Each group was divided into 2 subgroups according to the presence or not of at least 1 transferred TQE (1 with TQE; 1 without TQE; 2-3 with TQE, 2-3 without TQE; ≥4with TQE; ≥4withoutTQE). The clinicalpregnancy rateswerecomparedineach subgroup based on the presence or absence of at least one transferred TQE.

    Results

    During the study period, 636 women had at least one embryo to be transferred in thefirst fresh cycle (17.8% had 1 formed embryo [32.7% with TQEversus 67.3% without TQE], 42.1% of women had 2-3 formed embryos [55.6% with TQE versus 44.4% without TQE], and 40.1%ofpatientshad ≥4 formedembryos[73.7%withTQEversus26.3%withoutTQE]).The clinical pregnancy rate was significantly higher in the subgroup with ≥4 formed embryos with at least 1 transfered TQE (45.2%) compared with the subgroup without TQE (28.4%).

    Conclusions

    Having at least two available embryos and at least one TQE for embryo transfer are predictors of the pregnancy rates.

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  • Case Report

    Giant Condyloma (Buschke-Loewenstein Tumor) in a 16-year-old Patient: Case Report

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):471-476

    Summary

    Case Report

    Giant Condyloma (Buschke-Loewenstein Tumor) in a 16-year-old Patient: Case Report

    Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(9):471-476

    DOI 10.1055/s-0036-1593776

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    Abstract

    The Buschke-Loewenstein tumor is characterized by excessive growth of verrucous lesions on the genitals and/or perianal region. It is considered benign despite the high rate of recurrence and the possibility of malignant transformation. It is commonly associated with subtypes 6 and 11 of the human papillomavirus (HPV), and host 's immunity plays an important role in the development of the disease. Surgical excision is the recommended treatment in most cases. We present the case of a 16 years old female patient with extensive vulvar lesions successfully treated surgically.

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    Giant Condyloma (Buschke-Loewenstein Tumor) in a 16-year-old Patient: Case Report

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