Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):319-323
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):324-330
DOI 10.1590/S0100-72032006000600002
PURPOSE: to compare the maternal factors, clinical aspects and perinatal results in placental abruption during two periods. METHODS: retrospective analysis of placental abruption cases that occurred from January 1, 1994 through December 31, 1997 (period 94-97), and from April 4, 2001 through March 3, 2005 (period 01-05), in singleton delivery with birthweight higher than 500 g and after 20 weeks of gestation. The following factors were analyzed: maternal age, previous obstetric history, prenatal care, premature rupture of membranes, obstetric and/or clinical intercurrent events, vaginal bleeding, uterine tonus, fetal anomaly, mode of delivery, hemoamnion and maternal complication (hysterectomy, uterine atony, disseminated intravascular coagulation, acute renal failure, and maternal death), and the perinatal results. RESULTS: the rate of placental abruption was 0.78% (60 cases) in the period 94-97 (n=7692 deliveries), and 0.59% (51 cases) in the period 01-05 (n=8644 deliveries), without significant difference. A significant difference was observed between the periods 94-97 and 01-05 regarding mean number of previous gestations (3.5±2.4 and 2.6±1.8, p=0.04), patients without prenatal care (13.3 and 2.0%, p=0.03) and maternal intercurrences (38.3 and 64.7%, p=0.01). No significant difference was observed related to vaginal bleeding, tonus abnormalities and perinatal results, between the periods, but a higher proportion of hemoamnion in 94-97 was found when compared to 01-05 (28.3 and 11.8%, p=0.03). CONCLUSIONS: in spite of obstetrical advances, maternal complications and perinatal results were similar in the analyzed periods. The severity and the unexpected results emphasize the importance of prevention and adequate control of associated factors, when this pathology is approached.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):331-339
DOI 10.1590/S0100-72032006000600003
PURPOSE: to evaluate the impact of supplementary ferrous sulfate and dietary counseling on hemoglobin levels in pregnant women. METHODS: a total of 197 pregnant women were evaluated during antenatal care at a health center. The treatment group consisted of 105 women who were prescribed 60 mg dietary iron per day, received dietary counseling and had hemoglobin measured by a portable photometer between the 14th and 20th week of pregnancy. The treatment group was reevaluated according to hemoglobin levels and food intake by a semiquantitative food frequency questionnaire after the 34th week of pregnancy. The control group consisted of 92 women in a cross-sectional study, at no less than 34 weeks of pregnancy. Hemoglobin was analyzed by a portable photometer and anemia was defined concentrations of less than 11 g/dL. All pregnant women had their weight and height measured. Hierarchical logistic regression model was developed for the multivariate analysis. RESULTS: prevalence of anemia at the end of the third trimester was 31.6% in the treatment group and 26.1% in the control group (p=0.43). Use of the prescribed supplement was reported by 65% of women in the treatment group, of which 67.7% interrupted the treatment at some point. Principal reasons for interrupting treatment were forgetting (43.2%) and nausea or vomiting (27.2%). Risk of anemia in the third trimester was three times higher in women with less than 8 years of schooling. CONCLUSIONS: use of ferrous sulfate was not shown to be associated with lower prevalence of anemia. The results suggest that structural changes in socioeconomic conditions are needed in order to alter the current situation regarding iron deficiency anemia.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):340-344
DOI 10.1590/S0100-72032006000600004
PURPOSE: the study the effects of maternal cigarette smoking during pregnancy on placental maturation (calcifications) and the placental-uterine circulation, evaluated through umbilical and uterine Doppler. METHODS: prospective cohort study involving 244 pregnant women, 210 of them non-smokers and 34 smokers. Participants were submitted to four serial sonograms. The first was performed up to the 16th week of pregnancy to determine gestational age, and the other three at 28, 32 and 36 weeks for fetal biometry, evaluation of placental texture and Doppler studies of the uterine and umbilical arteries. Premature placental calcification was defined as grade III before 36 weeks. The chi2 and Fisher exact tests were used to compare placental grading, and the Mann-Whitney test to evaluate the resistance index of uterine and umbilical arteries. RESULTS: the frequency of grade III placenta and the resistance of the uterine arteries did not differ significantly between smokers and non-smokers, at all gestational ages. Umbilical artery Doppler was significantly higher in smokers than in non-smokers at 32 weeks. CONCLUSIONS: no association was found between cigarette smoking and premature placental calcification. Smoking was associated with increased umbilical artery resistance at 32 weeks.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):345-351
DOI 10.1590/S0100-72032006000600005
PURPOSE: to evaluate association between CD4+ cell count and cervical intraepithelial lesion severity in HIV-infected women. METHODS: cross-sectional study of 87 HIV-infected patients which were confirmed by previous serologic examinations. All had cervical HPV diagnosed by polymerase chain reaction (PCR). All patients underwent anamnesis, physical examinations and colposcopy. Cervix biopsy was performed when indicated by colposcopical examination. Histopathological results followed Richart's classification, adapted by Wright, and CD4+ cell count and cervical intraepithelial lesion severity association was analysed by comparison of means using analysis using analysis of variance (ANOVA). RESULTS: among 60 biopsied women 24 were found (40.0%) with CIN I, eight (13.3%) with CIN II, three (5%) with CIN III, 14 (23.3%) with chronic cervicitis and 11 with cytopathic effect of HPV, without cell polarity loss. This corresponds to 35 (58.3%) women with intraepithelial lesion of low grade (CIN I + HPV) and 11 (18.3%) with intraepithelial lesion of high grade (CIN II + CIN III). There was no significant association between CD4+ cell count mean and cervical intraepithelial lesion severity (p=0.901). CONCLUSIONS: there was no association between CD4+ cell count and cervical intraepithelial lesion severity diagnosed by histopathological examination.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):352-357
DOI 10.1590/S0100-72032006000600006
PURPOSE: to analyze the impact of urinary incontinence on women's quality of life, submitted or not to surgical treatment. METHODS: sixty women with urinary incontinence during stress were interviewed and divided into two groups classified as: S-CIR group, including 30 women not yet submitted to specific surgical treatment for urinary incontinence, and C-CIR group, including 30 women who had already undergone surgery. The scores obtained after the addition of values attributed to each question of the questionnaires were compared between the two groups. The number of patients who showed any impairment on quality of life due to specific symptoms of incontinence was also compared between groups. Data were analyzed by the variance test and the chi-square test, when applicable. RESULTS: symptoms, limitations and concerns related to urinary incontinence exhibited a strong negative impact on quality of life in patients from the S-CIR group. Impairment during physical exercises, domestic activities and daily working activities was the most important affected aspect in patients of the S-CIR group. Furtherimore, patients of the S-CIR group reported more fatigue, embarrassment, and excessive nervousness. Urine loss during stress followed by urgency were also significantly relevant aspects when groups were compared. CONCLUSIONS: the study allowed the identification and quantification of the derangements of quality of life due to urinary incontinence and demonstrated that these derangements either become less important or even disappear in women submitted to surgery.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):358-364
DOI 10.1590/S0100-72032006000600007
PURPOSE: to assess the frequency of stress and anxiety levels in infertile women, in order to obtain data for specific psychological intervention. METHODS: a cross-sectional study involving 152 infertile (mean age 30.3±5.4 years), and 150 healthy control women (25.7±7.9 years). All patients were evaluated with the Lipp's Inventory of Stress Symptoms and the State-Trait Anxiety Inventory. Considered dependent variables were: stress frequency and anxiety scores (state and trait). Statistical analysis was performed by the chi2 and Mann-Whitney tests, and logistical regression to test associations between response variables and considered risk factors. Statistical significance was defined as p<0.05. RESULTS: the stress was more frequent in the infertile group than in the control group (61.8 and 36.0%, respectively); however, no significant differences were observed between groups in relation to stress phases and predominant symptoms. With respect to anxiety, there were no significant differences between infertile and control groups as to median state scores (39.5 and 41.0, respectively) and anxiety trait scores (44.0 and 42.0, respectively). Factors significantly associated with greater risk for high anxiety scores in the infertile group were: unawareness of the causal factor, diagnostic phase investigation, and lack of children from other marriages. CONCLUSIONS: it can be concluded that infertile women are more vulnerable to stress; however, they are capable of adapting themselves to stressful events without serious physical or psychological compromise.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2006;28(6):365-372
DOI 10.1590/S0100-72032006000600008
As therapeutic approaches for oncologic diseases are being improved and an increase in the survival rates are being achieved, long-term complications of these therapies, initially infrequent, assume these days an important place when considering life quality. Among the long term repercussions appears the premature ovarian failure. According to the recommendations of the American Society of Clinical Oncology recently published, the only procedures available nowadays considered to be effective for female fertility preservation are: embryo cryopreservation, conservative gynecological surgery and oophoropexy in cases of local radiotherapy. All the other proposed techniques, surch as: ovarian suppression and oocyte and ovarian tissue cryopreservation, although present promising results, are still considered as experimental options. The best choice for fertility preservation in each specific case depends on patient's age, type of treatment, existence of a partner, time available until chemo- or radiotherapy beginning, and the ovarian metastatic potential of the tumor. In the present manuscript, the available and experimental techniques for fertility preservation are revised and discussed.