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8 articles
  • Editorial

    Infections by rapidly growing mycobacteria resistant to disinfectants: a national matter?

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):529-533

    Summary

    Editorial

    Infections by rapidly growing mycobacteria resistant to disinfectants: a national matter?

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):529-533

    DOI 10.1590/S0100-72032009001100001

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    Rapidly growing mycobacteria (RGM) are opportunistic microorganisms and widely distributed into aqueous environment and soil. Human RGM infections are usually associated with contaminated solutions or medical instruments used during invasive procedures. RGM postsurgical infections have recently emerged in Brazil and have caused national alert, considering the risk factors and epidemiological aspects. This study aimed at analysing the main factors linked to the recent RGM outbreaks, with focus on the national epidemic of Mycobacterium massiliense infections related to the BRA100 strains resistant to 2% glutaraldehyde commercial solutions commonly used for preoperative high-level disinfection. Based on previous studies and laboratorial results of assays and colaborations, it has been observed that the cases have been associated with videolaparoscopy for different applications and elective esthetic procedures, such as lipoaspiration and mammary prosthesis implant. Furthermore, outbreaks between 2004 and 2008 and the epidemic in Rio de Janeiro state may be considered particular Brazilian events. Although there are a few epidemiological published studies, some hypotheses based on common aspects related to most national nosocomial occurrences are possible, such as lack of protocols for cleaning and high-level disinfection, use of 2% glutaraldehyde as high-level disinfectant for surgical instruments, and dissemination of M. massiliense BRA100 by unknown mechanisms.

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  • Artigos Originais

    Orbital territory hyperperfusion in pregnant women with systemic lupus erythematosus

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):534-539

    Summary

    Artigos Originais

    Orbital territory hyperperfusion in pregnant women with systemic lupus erythematosus

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):534-539

    DOI 10.1590/S0100-72032009001100002

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    PURPOSE: to analyze the ophthalmic artery functioning in pregnant women with systemic lupus erythematosus (PL) without active renal disease as compared to non-pregnant women with lupus (NPL) without active renal disease, and to normal pregnant women (PN). METHODS: observational study that analyzed ophthalmic artery dopplervelocimetric variables of 20 PN, 10 PL and 17 NPL women. The variables analyzed were: pulsatility index (PI), final diastolic velocity (FDV) and velocity peak ratio (VPR). Mean and standard deviation of these indexes were calculated. For group mean comparison, analysis of variance (ANOVA) and the post-hoc Tukey test have been used, with confidence interval of 95% (p<0.05). RESULTS: the PN group showed the following means and standard deviations of ophthalmic artery parameters: PI=2,4±0,3; VPR=0,5±0,1 e FDV=5,1±2,1 cm/s. The PL and NPL groups showed the following values, respectively: PI=2,0±0,4 and 1,9±0,4; VPR=0,6±0,1 and 0,6±0,1; FDV=9,7±3,9 cm/s and 8,1±4,3 cm/s. There was not significant mean difference between the PL and NPL groups for PI, VPR or FDV. However, statistically significant mean differences were observed between PN and PL for PI, VPR and FDV, with higher values of FDV and VPR in the PL group. CONCLUSIONS: there was a reduction of ophthalmic artery vascular impedance with orbital hyperfusion in the two groups of women with lupus erythematosus as compared to normal pregnant women. These results may help to improve the understanding on pathophysiology of systemic lupus erythematosus. In addition, the present method may be applied in future studies as a complementary procedure for the differential diagnosis between pre-eclampsia and renal failure due to lupus.

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    Orbital territory hyperperfusion in pregnant women with systemic lupus erythematosus
  • Artigos Originais

    Fetal bilateral obstructive uropathies: ultrasound findings during pregnancy and postnatal outcomes

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):540-546

    Summary

    Artigos Originais

    Fetal bilateral obstructive uropathies: ultrasound findings during pregnancy and postnatal outcomes

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):540-546

    DOI 10.1590/S0100-72032009001100003

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    PURPOSE: to verify the association between ultrasonographic signs during gestation and post-delivery evolution in fetuses with bilateral obstructive uropathies, followed up in an expectant way. METHODS: fetuses with bilateral obstructive uropathies presenting severe oligoamnios and narrow thorax have been compared with fetuses with bilateral obstructive uropathies without those alterations, concerning the presence or absence of cysts in both kidneys, and the presence or absence of parenchymal hyperechogenicity in both kidneys. Cases of neonatal death were compared with cases of neonatal discharge from the nursery, regarding the same renal echographic aspects mentioned above, the presence of severe oligoamnios and narrow thorax. The sensitivity, specificity, positive and negative predictive value of the presence of bilateral renal cysts, bilateral renal hyperechogenicity, severe oligoamnios and narrow fetal thorax for the neonatal death were calculated. RESULTS: severe oligoamnios and narrow thorax were more frequent (p=0.03; p<0.001) in fetuses with bilateral renal cysts, as compared to those with echographically normal renal parenchyma. Neonatal death was more frequent among cases with severe oligoamnios (p<0.001), narrow thorax (p<0.001) and bilateral renal cysts (p<0.002), when respectively compared with cases without those alterations. The best values of sensitivity, specificity, positive and negative predictive value for the death of neonatal/breastfeeding infants were obtained using the echographic aspect of narrow thorax, and were 81.8, 100, 100 and 79.3%, respectively. CONCLUSIONS: in cases of fetuses with bilateral obstructive uropathies followed up in an expectant way, the ultrasonographic signs more associated to bad prognosis are severe oligoamnios, narrow fetal thorax and presence of bilateral renal cysts.

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  • Artigos Originais

    Computerized cardiotocography analysis of fetal heart response to acoustic stimulation

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):547-551

    Summary

    Artigos Originais

    Computerized cardiotocography analysis of fetal heart response to acoustic stimulation

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):547-551

    DOI 10.1590/S0100-72032009001100004

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    PURPOSE: to study the effect of acoustic stimulation in the fetal cardiac response, according to parameters from computerized cardiotocography in low risk pregnancies. METHODS: twenty low risk pregnant women were included in the study, according to the following criteria: age over 18; single gestation, living fetus; gestational age between 36 and 40 weeks; amniotic liquid index over 8.0 cm and absence of fetal malformation. Cases with post-natal diagnosis of fetal anomaly were excluded. Computerized cardiotocography was performed for 20 minutes, before and after fetal acoustic stimulation. Results were analyzed by the t test for dependent samples, with significance level at p<0.05. RESULTS: acoustic stimulation was successfully performed in all cases analyzed. By the analysis of the cardiotocographic parameters, there was no significant difference when the pre and post-stimulation parameters were compared: average number of fetal movements per hour (55.6 versus 71.9, p=0.1); mean basal fetal heart rate (FHR) (135.2 versus 137.5 bpm, p=0.3); mean FHR increases>10 bpm (6.5 versus 6.8, p=0.7); mean FHR increases>15 bpm (3.8 versus 4.3, p=0.5); mean duration of high FHR variation episodes (11.4 versus 10.9 min, p=0.7); mean duration of low FHR variation episodes (2.5 versus 1.1 min, p=0.2), and mean short-term variation (10.6 versus 10.9 ms, p=0.6). CONCLUSIONS: in low risk gestations at term, computerized cardiotocography has not evidenced differences in the FHR parameters after the fetal sonic stimulation.

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  • Artigos Originais

    Transdermal nitroglycerin versus oral nifedipine administration for tocolysis: a randomized clinical trial

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):552-558

    Summary

    Artigos Originais

    Transdermal nitroglycerin versus oral nifedipine administration for tocolysis: a randomized clinical trial

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):552-558

    DOI 10.1590/S0100-72032009001100005

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    PURPOSE: to compare the effectiveness of transdermal nitroglycerin with oral nifedipine in the inhibition of preterm delivery. METHODS: a clinical essay has been performed with 50 women in preterm delivery, randomly divided into two groups, 24 receiving oral nifedipine (20 mg), and 26, transdermal nitroglycerin (10 mg patch). Patients with a single gestation, between the 24th and the 34th weeks and diagnosis of preterm delivery were selected. Women with fetal malformation and clinical or obstetric diseases were excluded. The variables analyzed were: effective tocolysis, time needed for tocolysis, recurrence frequency, progression to preterm delivery, and side effects. RESULTS: tocolysis efficacy in the first 12 hours was similar between the groups (nitroglycerin: 84.6% versus nifedipine: 87.5%; p=0.50). The time average time needed for tocolysis was also similar (6.6 versus 5.8 hours; p=0.30). There was no difference between the groups, concerning the recurrence of preterm delivery (26.9 versus 16.7%; p=0.30), and neither in the rate of preterm delivery within 48 hours (15.4 versus 12.5%; p=0.50). Nevertheless, the cephalea rate was significantly higher in the Nitroglycerin Group (30.8 versus 8.3%; p=0.04). CONCLUSIONS: transdermal nitroglycerin has presented similar effectiveness to oral nifedipine to inhibit preterm delivery in the first 48 hours, however with higher cephalea frequency.

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    Transdermal nitroglycerin versus oral nifedipine administration for tocolysis: a randomized clinical trial
  • Artigos Originais

    Comparison of two methods for the investigation of maternal mortality in a municipality of the Brazilian Southeast

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):559-565

    Summary

    Artigos Originais

    Comparison of two methods for the investigation of maternal mortality in a municipality of the Brazilian Southeast

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):559-565

    DOI 10.1590/S0100-72032009001100006

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    PURPOSE: to compare maternal death data from the National Death Information System (DIS), with a death survey of 10 to 49 year-old women at reproductive age (RAMOS), in order to identify sub-notification and to search for causes of maternal death (MD) from 1999 to 2006. METHODS: population based temporal series taken from death certificate (DC) information from Fundação Sistema Estadual de Análise de Dados (SEADE) database, with the death causes codified by the International Classification of Diseases (ICD), tenth revision, and the number of born alive babies (BA). Death was categorized into declared, presumptive MD and non-maternal. The identification of cases was done from a list with both the birth and death dates in the municipal morgues, and further information was obtained in the epidemiological sector of the Municipal Committee of Surveillance of Maternal Death (MCSMD). Information on MD was raised in the DIS. Sub-notification rates in cases of declared and non-declared MD were identified, maternal official death rates (MDR) and the adjusted factor for the period were calculated and corrected, and MD cases were reviewed and classified. RESULTS: twelve MD were identified, six of them declared and six non-declared. Sub-notification rate was 50%, giving an adjusting factor equal to 2. The official MDR was 14.7 and the corrected one was 29.4 deaths by 100,000 born alive. In most of the cases, the basic causes of death were mistaken. Direct obstetric causes were more prevalent, among them eclampsia and HELLP syndrome, followed by infections. CONCLUSIONS: political and administrative measures are needed for the effective action of MD survey committees. The prevalence of direct obstetric causes indicates failures in maternal and perinatal care.

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  • Artigos Originais

    Maternal mortality due to pre-eclampsia/eclampsia in a state in Southern Brazil

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):566-573

    Summary

    Artigos Originais

    Maternal mortality due to pre-eclampsia/eclampsia in a state in Southern Brazil

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):566-573

    DOI 10.1590/S0100-72032009001100007

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    PURPOSE: to identify the profile, tendency and causes of maternal death by pre-eclampsia/eclampsia in Paraná. METHODS: descriptive, transversal cohort study on maternal death by pre-eclampsia/eclampsia from 1997 to 2005. Data were obtained from case studies prepared by Maternal Death Committees that employ the Reproductive Age Mortality Survey Method to examine all the cases of death among women in fertile age. The general and specific maternal death rate (MDR) by pre-eclampsia/eclampsia were considered. To evaluate the tendency, triennial periods have been compared, two by two, taking into consideration the MDR of each period (p<0.05). In the triennial period from 2003 to 2005, 56 deaths by pre-eclampsia/eclampsia were analyzed. The variables focused were: age, income, schooling, gestation number and complications, pre-natal conditions, signs and symptoms related to the condition, delivery route, the time gestation was interrupted, the newborn conditions, access and treatment, ability to avoid and prevention measures. RESULTS: the general triennial MDR has presented significant decline, with 64.3/100,000 born-alive babies. There has been stability along the period for MDR by hypertensive disorder, with MDR of 11.8/100,000 born-alive. Primiparous women, women over 40 and with low socio-economical status have presented higher risks. In relation to the treatment, there has been underuse or inadequate use of conventional medicines for severe pre-eclampsia and eclampsia. The committees' analysis indicated that all the maternal death due to these conditions could have been avoided. CONCLUSIONS: actions aiming at minimizing the set of causes that lead to death by pre-eclampsia in Paraná should be enforced, including the training and monitoring of health professionals in order to apply the treatment protocols, besides the formalization of a reference net of clinics and hospitals, qualified for the care of high risk pregnancy and its intercurrences, to which pre-natal pregnant women are enrolled.

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  • Artigos Originais

    Condom use intention among young students in Belo Horizonte: an alert to gynecologists

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):574-580

    Summary

    Artigos Originais

    Condom use intention among young students in Belo Horizonte: an alert to gynecologists

    Revista Brasileira de Ginecologia e Obstetrícia. 2009;31(11):574-580

    DOI 10.1590/S0100-72032009001100008

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    PURPOSE: to investigate factors that motivate safe sex practice, searching for antecedents of the intention to use condom among the population of young students in Belo Horizonte. METHODS: a survey based on the Theory of Planned Behavior (TPB) has been carried out in a sample of 732 students, with ages from 18 to 19 years old. Using the multiple regression analysis on data obtained from an anonymous questionnaire, the importance of antecedents of the intention to use condom, such as: attitude, subjective norm, moral norm, resistance to temptation and perceived control, was investigated. Differences in behavior and attitudes between high and low social classes and between men and women were also assessed, through the t-test for means' comparison between independent samples. RESULTS: in the overall sample, the significant association of attitude and behavioral intention was not detected In the TPB, a higher percent of the intention variance was explained when only one of the partners was responsible for the decision of using the condom (intention-me), than when it was a joint decision of the couple (intention-us). There has been no significant difference between high and low social class groups, but differences have been found between men and women. Men have shown less resistance to the temptation of not using condom. In the evaluation of social pressure (subjective norm), medical doctors and mothers seem to have more influence on the intention to use condom, especially among women. The inclusion of the moral norm antecedent has increased the explained variance in the intention to use condom from 22 to 31%. CONCLUSIONS: attitude differences between men, less resistant to the temptation of not using condom, and women, who highlight the importance of gynecologists and parents' influence in advising about safe sex, may guide campaigns to promote the regular use of condoms.

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    Condom use intention among young students in Belo Horizonte: an alert to gynecologists

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