Trabalhos Originais Archives - Revista Brasileira de Ginecologia e Obstetrícia

  • Trabalhos Originais

    Toxoplasmosis: seroprevalence in postpartum women attended by SUS (Brazilian Public Health System)

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):627-632
    11-23-2004

    Summary

    Trabalhos Originais

    Toxoplasmosis: seroprevalence in postpartum women attended by SUS (Brazilian Public Health System)

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):627-632
    11-23-2004

    DOI 10.1590/S0100-72032004000800006

    Views94

    OBJECTIVE: to establish the rate of toxoplasmosis soroprevalence in postpartum women, attended in two hospitals of the Public Health System (SUS) in Cuiabá, and its correlation with age, previous abortion and women's knowledge of the disease. METHODS: a cross-sectional study including 205 women with ages from 14 to 43 (mean 22.4) years old, attended in these hospitals for two months, in the first or second days postpartum. Each woman answered a short questionnaire and had peripheral blood sample collected. Blood samples were stored at 20°C until assay. The seroprevalence was determined by quantitative detection of specific IgG antibody against Toxoplasma gondii, using a microparticle enzyme immunoassay. All samples were assayed at the same time. RESULTS: The average number of pregnancies in the women included in this study was 2.2, and the majority of them was pregnant for the first time. The seroprevalence found was 70.7% (165 of 205 women). No statistical correlation was found between seroprevalence and age (p = 0.967) or previous abortion (p = 0.82). Most of the women in this study (78%) did not know about toxoplasmosis and no statistical correlation was found between this condition and seroprevalence (p = 0.49). CONCLUSION: the high seroprevalence found in the present study is in accordance with surveys previously reported in our country and other developing countries. Among the women included in this study, an expressive number (29.3%) is still under risk of contamination. The lack of statistical correlation between seroprevalence and women's age, lack of knowledge about the disease and report of previous abortion is in accordance with some previous studies and in disagreement with others.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Trabalhos Originais

    Social indicators of pregnant adolescents: a case control study

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):633-639
    11-23-2004

    Summary

    Trabalhos Originais

    Social indicators of pregnant adolescents: a case control study

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):633-639
    11-23-2004

    DOI 10.1590/S0100-72032004000800007

    Views114

    PURPOSE: to check whether there were differences in some social indicators between adolescent and adult pregnant women in the city of Ribeirão Preto, from January 1992 to December 1996. METHODS: the information was obtained from hospital discharge forms and was analyzed at the Hospital Data Processing Center of the FMRP-USP. The analyzed parameters were: number and types of deliveries, category of hospital admission, occupation, and obstetric diagnosis. The 6.04a text processor Epi-Info System, a data bank and statistics of epidemiology produced by the Centers of Disease Control and Prevention (Atlanta, GA, USA), and Dbase IV were used to process the information. The association between variables was tested by the chi² test, with level of significance set at 5%, using the GraphPad Prism version 2.0, 1995 software. RESULTS: a total of 43,253 deliveries occurred during this period, among which 7,134 (16.5%) corresponded to adolescent deliveries, while 36,119 (83.5%) to adult deliveries. The number of deliveries by adolescent girls increased 25.5% along this period. The proportion of adolescent deliveries in the unified health system category of admission increased, and it was higher than that of the adults'. Only 14.1% of the adolescents belonged to the economically active population, comparing with 34.8% of the adults. Only 6.8% of the adolescents were students, while 79.0% were house-workers or had a nonpaid occupation. In the analyzed period, the ratio of vaginal delivery increased among the adolescents, as compared to that of the adults. The ratio of cesarean delivery persisted stable and higher among the adults. Premature delivery and false labor were significantly more frequent among the adolescents. CONCLUSION: the number of deliveries increased among the adolescents, and most of them were normal. The ratio of admission by the unified health system category and that of vaginal delivery were higher among the adolescents. There were more adolescents without an economically active work. Thus, we recommend strategies to prevent adolescent pregnancy, mainly among the poor population.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Trabalhos Originais

    Venous-arterial indices in the prediction of acidemia at birth in pregnancies with placental insufficiency

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):641-647
    11-23-2004

    Summary

    Trabalhos Originais

    Venous-arterial indices in the prediction of acidemia at birth in pregnancies with placental insufficiency

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):641-647
    11-23-2004

    DOI 10.1590/S0100-72032004000800008

    Views177

    OBJECTIVE: to investigate whether it is possible to predict acidemia at birth in pregnancies with placental insufficiency using venous-arterial indices: pulsatility index for vein (PIV) of the ductus venosus (DV) over PI of the middle cerebral artery (MCA) and PIV of the DV over PI of the umbilical artery, and establish cut-off values for this prediction. PATIENTS AND METHODS: this was a prospective cross-sectional study involving forty-seven patients with placental insufficiency (umbilical artery resistance and pulsatility indices above the 95th percentile for gestational age) who were submitted to Dopplervelocimetry in the last 24 hours before delivery. All pregnancies were singleton, over 26 weeks of age and without structural or chromosome anomalies. Arterial cord blood was obtained for gasometry immediately after birth. Acidemia was defined as umbilical arterial pH < 7.20 in the absence of uterine contractions and pH < 7.15 in the presence of contractions. Metabolic or mixed acidemia at birth were considered pathological. A ROC curve was calculated for the venous-arterial indices: PIV DV/PI umbilical artery (UA) and PIV DV/PI MCA. A cut-off value was established and sensitivity, specificity, accuracy, positive and negative predictive values and positive and negative likelihood ratios were calculated. RESULTS: The DV/UA PI index was not a good predictor of acidemia at birth. The DV/MCA PI index was related to acidemia at birth (area under the curve 0,785, p = 0,004). The cut-off value was: 0,582, sensitivity 66,7%, specificity 77,1 and accuracy 74,5%. CONCLUSION: the PIV DV/PI MCA ratio is adequate for predicting acidemia at birth in pregnancies with placental insufficiency. The cut-off value was: 0,582.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Trabalhos Originais

    Noninvasive fetal anemia diagnosis by middle cerebral artery peak systolic velocity waveform measurement

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):649-653
    11-23-2004

    Summary

    Trabalhos Originais

    Noninvasive fetal anemia diagnosis by middle cerebral artery peak systolic velocity waveform measurement

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):649-653
    11-23-2004

    DOI 10.1590/S0100-72032004000800009

    Views107

    PURPOSE: to assess the correlation between middle cerebral artery peak systolic velocity and umbilical cord blood hemoglobin concentration and to determine its diagnostic value. PATIENTS AND METHODS: a cross-sectional prospective study was performed from January 2000 to May 2003. Forty-four isoimmunized pregnant women underwent a protocol for the identification of fetal hemolysis. When intrauterine transfusions were indicated, the umbilical cord blood hemoglobin concentration was measured at the beginning of the procedure. Each intrauterine transfusion preceded by Doppler velocimetry of the middle cerebral artery was regarded as one case, summing up eighty-three procedures. In all cases, the middle cerebral artery Doppler examinations were performed within the three hours preceding fetal blood sample collection. The systolic velocity peak was recorded and considered abnormal when its value was above 1.5 times the median for the corresponding gestational age. Hemocue® (B-Hemoglobin Photometer Hemocue AB; Angelholm, Sweden) was the device used to measure fetal hemoglobin concentration. The relationship between middle cerebral artery peak systolic velocity and cord blood hemoglobin was obtained by the chi2 test, considered significant at p<0.05. RESULTS: in thirty-three cases the cord blood hemoglobin concentration was below 10.0 g/dL. There was a strong correlation between the two measured variables (p<0.001). The middle cerebral artery peak systolic velocity with values above 1.5 times the median was associated with cord blood hemoglobin concentration below 10 g/mL (p<0,001). The sensitivity of an increased middle cerebral artery peak systolic velocity was 75.8% for the detection of a cord blood hemoglobin level of 10 g/dL or lower. CONCLUSION: the middle cerebral artery peak systolic velocity can be used as a noninvasive method for the diagnosis of fetal anemia.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Trabalhos Originais

    Direct determinants of elective preterm birth and neonatal results

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):655--6662
    11-23-2004

    Summary

    Trabalhos Originais

    Direct determinants of elective preterm birth and neonatal results

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(8):655--6662
    11-23-2004

    DOI 10.1590/S0100-72032004000800010

    Views54

    OBJECTIVE: to characterize the features of pregnant women who had elective preterm delivery, and correlate clinical and obstetrical diagnosis with neonatal results. METHOD: A total of 100 pregnant women admitted in the Obstetric Clinic ward and their respective newborns has been evaluated. The inclusion criteria were: single pregnancy, confirmed gestational age by an early scan, absence of labor symptoms and the presence of a maternal or fetal condition leading to preterm delivery indication. The direct causes of elective preterm delivery were classified in groups, to relate them to the neonatal results, taking into account the gestational age. To assess the neonatal results, the following criteria were analyzed: acidosis; 1st and 5st minute Apgar score lower than 7; intracranial hemorrhage; neonatal death; sepsis and respiratory distress syndrome. Statistical analysis used to correlate the causes of delivery and the gestational age to the neonatal results was done by log-linear models. RESULTS: One patient was excluded from the study due to fetal malformation. The most common direct causes of delivery were prenatal fetal distress (49.5%), hypertensive syndromes (21.2%), intra uterine growth restriction (13.1%) and others (16.2%). Among the main neonatal complications there were asphyxia (33.3%), acidosis (30.4%), respiratory distress syndrome (RDS) (26.3%), sepsis (22.2%), intracranial hemorrhage (21.2%) and neonatal death (13.1%). The cause of delivery was associated with acidosis and RDS by log-linear models and the gestational age was associated with RDS, 1st minute Apgar <7, sepsis, intracranial hemorrhage and neonatal death. CONCLUSIONS: the cause of delivery influences the neonatal results. Nevertheless, the most severe complications are directly dependent on the gestational age of delivery. Therefore, the prenatal diagnosis should be rigorously evaluated by the obstetrician, so that the decision to interrupt the pregnancy could be taken at the suitable moment, thus avoiding neonatal complications.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Trabalhos Originais

    Prevalence of vaginal and anorectal colonization by group B streptococcus in pregnant women in the last three months of gestation

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):543-549
    10-15-2004

    Summary

    Trabalhos Originais

    Prevalence of vaginal and anorectal colonization by group B streptococcus in pregnant women in the last three months of gestation

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):543-549
    10-15-2004

    DOI 10.1590/S0100-72032004000700006

    Views110

    PURPOSE: to study the prevalence of colonization by group B Streptococcus in pregnant women in the last three months of gestation, and to evaluate the association of colonization with demographic and clinical maternal variables. METHODS: from October 8, 2002 to March 26, 2003, a transversal study of prevalence of colonization by group B Streptococcus was carried out in 309 pregnant women in the last three months of gestation. Samples of vaginal and anorectal secretions were collected and were tested for presumptive identification of group B Streptococcus. The pregnant women were studied according to race, age, level of instruction, family income, number of gestations, gestational age, history of urinary tract infection during present pregnancy, premature rupture of membranes and duration of ruptured membranes, intrapartum fever, chorioamnionitis, meconium in the amniotic fluid, spontaneous or cesarean section delivery, postpartum fever, and postpartum endometritis. RESULTS: fourty-six pregnant women were diagnosed with group B Streptococcus: 26 of them (56.5%) had positive vaginal culture, 8 (17.4%) positive anorectal culture and 12 (26.5%) had both vaginal and anorectal positive cultures. None of the maternal variables were statistically significant with respect to group B Streptococcus colonization. The results were submitted to chi2 bivariate analysis and, when appropriate, Fisher's exact test. CONCLUSION: the prevalence rate of vaginal and anorectal colonization by group B Streptococcus in pregnant women in the last three months of gestation, in Londrina - Paraná, was 14.9%.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Trabalhos Originais

    Diagnostic accuracy of hysterosalpingography and transvaginal sonography to evaluate uterine cavity diseases in patients with recurrent miscarriage

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):527-533
    10-14-2004

    Summary

    Trabalhos Originais

    Diagnostic accuracy of hysterosalpingography and transvaginal sonography to evaluate uterine cavity diseases in patients with recurrent miscarriage

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):527-533
    10-14-2004

    DOI 10.1590/S0100-72032004000700004

    Views112

    PURPOSE: to evaluate the diagnostic accuracy of hysterosalpingography (HSG) and transvaginal sonography (TVS) in terms of detecting uterovaginal anomalies in women with a history of recurrent miscarriage. METHODS: eighty patients who presented two or more consecutive miscarriages were submitted to HSG, TVS and hysteroscopy (HSC). The following diagnoses were considered separately: uterine malformations, intrauterine adhesions and polypoid lesions. Hysteroscopy was the gold standard. The matching among the different methods was evaluated by the kappa coefficient and its significance was tested. The significance level was 0.05 (alpha=5%). Sensitivity, specificity, positive and negative predictive values, with 95% of statistical confidence interval, were calculated. RESULTS: uterovaginal anomalies were detected in 29 (36.3%) patients: 11 (13.7%) were uterine malformations, 17 (21.3%) intrauterine adhesions and one (1.3%) a polypoid lesion. The global matching between HSG and HSC was 85.5%, while between TVS and HSC it was only 78.7%. The best accuracy of HSG appeared to be for the diagnosis of uterine malformations and intrauterine adhesions (diagnostic accuracy of 97.5 and 95%, respectively). For the diagnosis of polypoid lesions, HSG had a diagnostic accuracy of only 92.5%, due to the low rate of positive predictive value (14.3%). TVS had a worse accuracy for all diagnoses, 93.7% for the diagnosis of uterine malformations and 85% for intrauterine adhesions, due to low sensitivity. CONCLUSIONS: histerosalpingography showed a good diagnostic accuracy for the diagnosis of uterine cavity diseases. TVS had good specificity, but with low sensitivity.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • Trabalhos Originais

    Diagnosis of fetal growth restriction by transverse cerebellar diameter/abdominal circumference ratio

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):535-541
    10-14-2004

    Summary

    Trabalhos Originais

    Diagnosis of fetal growth restriction by transverse cerebellar diameter/abdominal circumference ratio

    Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):535-541
    10-14-2004

    DOI 10.1590/S0100-72032004000700005

    Views83

    PURPOSE: to evaluate the validity of transverse cerebellar diameter (TCD)/abdominal circumference (AC) ratio in the diagnosis of fetal growth restriction (FGR), determining its best cutoff value and accuracy in symmetric and asymmetric FGR. METHOD: a prospective cross-sectional study, carried out in 250 pregnant women with singleton pregnancies, gestational age between 20 and 42 weeks, with ultrasound confirmation. The TCD measurement was obtained by placing the calipers at the outer margins of the cerebellum, after its localization in the posterior fossa, and slightly rotating the transducer below the plane of the thalami. The abdominal circumference was measured at the on junction of the left portal and umbilical veins. The best TCD/AC cutoff ratio was established by the receiver operator characteristic (ROC) curve. Neonates with TCD/AC ratio greater than the cutoff value were diagnosed as having FGR. We classified as gold standard for FGR the newborn infants who presented birth weight below the 10th percentile. Neonates showing FGR and Rohrer ponderal index between 2.2 and 3 were labeled as symmetric and below 2.2, asymmetric. RESULTS: the cutoff value calculated by the ROC curve for TCD/AC ratio was 16.15. The sensitivity, specificity, accuracy, positive and negative predictive values, and likelihood ratio for positive and negative tests were 77.4, 82.6, 38.7, 96.3, 82, 4.5 and 3.7%, respectively. In the symmetric FGR, sensitivity and specificity were 80.8 and 81.7%, respectively. In the asymmetric FGR, sensitivity and specificity were 60 and 75%, respectively. CONCLUSION: TCD/AC ratio is an effective method in symmetric and asymmetric FGR diagnosis.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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