-
Review Article
Perinatal Outcomes after Fetal Endoscopic Tracheal Occlusion for Isolated Congenital Diaphragmatic Hernia: Rapid Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(1):74-82
02-28-2022
Summary
Review ArticlePerinatal Outcomes after Fetal Endoscopic Tracheal Occlusion for Isolated Congenital Diaphragmatic Hernia: Rapid Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(1):74-82
02-28-2022Views153Abstract
Objective
To compare the perinatal outcomes of fetuses with isolated congenital diaphragmatic hernia after fetal endoscopic tracheal occlusion (FETO) and antenatal expectant management.
Data sources
In this rapid review, searches were conducted in the MEDLINE, PMC, EMBASE and CENTRAL databases between August 10th and September 4th, 2020. Randomized controlled trials (RCTs), quasi-RCTs or cluster-RCTs published in English in the past ten years were included.
Study selection
We retrieved 203 publications; 180 studies were screened by abstract. Full-text selection was performed for eight studies, and 1 single center RCTmet the inclusion criteria (41 randomized women; 20 in the FETO group, and 21 in the control group).
Data collection
Data collection was performed independently, by both authors, in two steps (title and abstract and full-text reading).
Data synthesis
There were no cases of maternal mortality. The mean gestational age at delivery was of 35.6±2.4 weeks in the intervention group, and of 37.4±1.9 weeks among the controls (p<0.01). Survival until 6 months of age was reported in 50% of the intervention group, and in 5.8% of the controls (p<0.01; relative risk: 10.5; 95% confidence interval [95%CI]: 1.5-74.7). Severe postnatal pulmonary hypertension was found in 50% of the infants in the intervention group, and in 85.7% of controls (p=0.02; relative risk: 0.6; 95%CI: 0.4-0.9). An analysis of the study indicated some concerns of risk of bias. The quality of evidence was considered moderate to low.
Conclusion
Current evidence is limited but suggests that FETO may be an effective intervention to improve perinatal outcomes.
Key-words congenital diaphragmatic herniasPrenatal ultrasonographyPrognosissystematic reviewultrasound diagnosisSee moreViews153
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticlePerinatal Outcomes after Fetal Endoscopic Tracheal Occlusion for Isolated Congenital Diaphragmatic Hernia: Rapid Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(1):74-82
02-28-2022Views153Abstract
Objective
To compare the perinatal outcomes of fetuses with isolated congenital diaphragmatic hernia after fetal endoscopic tracheal occlusion (FETO) and antenatal expectant management.
Data sources
In this rapid review, searches were conducted in the MEDLINE, PMC, EMBASE and CENTRAL databases between August 10th and September 4th, 2020. Randomized controlled trials (RCTs), quasi-RCTs or cluster-RCTs published in English in the past ten years were included.
Study selection
We retrieved 203 publications; 180 studies were screened by abstract. Full-text selection was performed for eight studies, and 1 single center RCTmet the inclusion criteria (41 randomized women; 20 in the FETO group, and 21 in the control group).
Data collection
Data collection was performed independently, by both authors, in two steps (title and abstract and full-text reading).
Data synthesis
There were no cases of maternal mortality. The mean gestational age at delivery was of 35.6±2.4 weeks in the intervention group, and of 37.4±1.9 weeks among the controls (p<0.01). Survival until 6 months of age was reported in 50% of the intervention group, and in 5.8% of the controls (p<0.01; relative risk: 10.5; 95% confidence interval [95%CI]: 1.5-74.7). Severe postnatal pulmonary hypertension was found in 50% of the infants in the intervention group, and in 85.7% of controls (p=0.02; relative risk: 0.6; 95%CI: 0.4-0.9). An analysis of the study indicated some concerns of risk of bias. The quality of evidence was considered moderate to low.
Conclusion
Current evidence is limited but suggests that FETO may be an effective intervention to improve perinatal outcomes.
Key-words congenital diaphragmatic herniasPrenatal ultrasonographyPrognosissystematic reviewultrasound diagnosisSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
-
Review Article
Efficacy of Transversus Abdominis Plane Block in the Reduction of Pain and Opioid Requirement in Laparoscopic and Robot-assisted Hysterectomy: A Systematic Review and Meta-analysis
- Claudia López-Ruiz
, - Jerutsa Catalina Orjuela ,
- Diego Fernando Rojas-Gualdrón ,
- Marcela Jimenez-Arango ,
- José Fernando de los Ríos , [ ... ],
- Claudia Vargas
02-28-2022
Summary
Review ArticleEfficacy of Transversus Abdominis Plane Block in the Reduction of Pain and Opioid Requirement in Laparoscopic and Robot-assisted Hysterectomy: A Systematic Review and Meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(1):55-66
02-28-2022- Claudia López-Ruiz ,
- Jerutsa Catalina Orjuela ,
- Diego Fernando Rojas-Gualdrón ,
- Marcela Jimenez-Arango ,
- José Fernando de los Ríos ,
- Elsa Maria Vásquez-Trespalacios ,
- Claudia Vargas
Views351Abstract
Objective
To summarize the available evidence of TAP Block in efficacy in laparoscopic or robotic hysterectomy.
Data Sources
We searched databases and gray literature for randomized controlled trials in which transversus abdominis plane (TAP) block was compared with placebo or with no treatment in patients who underwent laparoscopic or robot-assisted hysterectomy.
Method of Study
Selection Two researchers independently evaluated the eligibility of the selected articles. Tabulation, Integration, and Results Seven studies were selected, involving 518 patients. Early postoperative pain showed a difference in the mean mean difference (MD): - 1.17 (95% confidence interval [CI]: - 1.87-0.46) in pain scale scores (I2=68%), which was statistically significant in favor of using TAP block, but without clinical relevance; late postoperative pain: DM 0.001 (95%CI: - 0.43-0.44; I2=69%); opioid requirement: DM 0.36 (95%CI: - 0.94-1.68; I2=80%); and incidence of nausea and vomiting with a difference of 95%CI=- 0.11 (- 0.215-0.006) in favor of TAP.
Conclusion
With moderate strength of evidence, due to the high heterogeneity and imbalance in baseline characteristics among studies, the results indicate that TAP block should not be considered as a clinically relevant analgesic technique to improve postoperative pain in laparoscopic or robotic hysterectomy, despite statistical significance in early postoperative pain scale scores.
Key-words laparoscopic hysterectomyOpioidPainrobotic-assisted hysterectomytransversus abdominis plane blockSee moreViews351This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleEfficacy of Transversus Abdominis Plane Block in the Reduction of Pain and Opioid Requirement in Laparoscopic and Robot-assisted Hysterectomy: A Systematic Review and Meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(1):55-66
02-28-2022- Claudia López-Ruiz ,
- Jerutsa Catalina Orjuela ,
- Diego Fernando Rojas-Gualdrón ,
- Marcela Jimenez-Arango ,
- José Fernando de los Ríos ,
- Elsa Maria Vásquez-Trespalacios ,
- Claudia Vargas
Views351Abstract
Objective
To summarize the available evidence of TAP Block in efficacy in laparoscopic or robotic hysterectomy.
Data Sources
We searched databases and gray literature for randomized controlled trials in which transversus abdominis plane (TAP) block was compared with placebo or with no treatment in patients who underwent laparoscopic or robot-assisted hysterectomy.
Method of Study
Selection Two researchers independently evaluated the eligibility of the selected articles. Tabulation, Integration, and Results Seven studies were selected, involving 518 patients. Early postoperative pain showed a difference in the mean mean difference (MD): - 1.17 (95% confidence interval [CI]: - 1.87-0.46) in pain scale scores (I2=68%), which was statistically significant in favor of using TAP block, but without clinical relevance; late postoperative pain: DM 0.001 (95%CI: - 0.43-0.44; I2=69%); opioid requirement: DM 0.36 (95%CI: - 0.94-1.68; I2=80%); and incidence of nausea and vomiting with a difference of 95%CI=- 0.11 (- 0.215-0.006) in favor of TAP.
Conclusion
With moderate strength of evidence, due to the high heterogeneity and imbalance in baseline characteristics among studies, the results indicate that TAP block should not be considered as a clinically relevant analgesic technique to improve postoperative pain in laparoscopic or robotic hysterectomy, despite statistical significance in early postoperative pain scale scores.
Key-words laparoscopic hysterectomyOpioidPainrobotic-assisted hysterectomytransversus abdominis plane blockSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- Claudia López-Ruiz
-
Review Article
Underestimation Rate in the Percutaneous Diagnosis of Radial Scar/Complex Sclerosing Lesion of the Breast: Systematic Review
- Ana Beatrice Bonganha Zanon ,
- Jonathan Yugo Maesaka ,
- Bruna Bello Chequin ,
- Ana Gabriela de Siqueira Santos ,
- Edmund Chada Baracat , [ ... ],
- José Roberto Filassi
02-28-2022
Summary
Review ArticleUnderestimation Rate in the Percutaneous Diagnosis of Radial Scar/Complex Sclerosing Lesion of the Breast: Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(1):67-73
02-28-2022- Ana Beatrice Bonganha Zanon ,
- Jonathan Yugo Maesaka ,
- Bruna Bello Chequin ,
- Ana Gabriela de Siqueira Santos ,
- Edmund Chada Baracat ,
- José Roberto Filassi
Views127See moreAbstract
Objective
To evaluate the underestimation rate in breast surgical biopsy after the diagnosis of radial scar/complex sclerosing lesion through percutaneous biopsy.
Data Sources
A systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. The PubMed, SciELO, Cochrane, and Embase databases were consulted, with searches conducted through November 2020, using specific keywords (radial scar OR complex sclerosing lesion, breast cancer, anatomopathological percutaneous biopsy AND/OR surgical biopsy).
Data collection
Study selection was conducted by two researchers experienced in preparing systematic reviews. The eight selected articles were fully read, and a comparative analysis was performed.
Study selection
A total of 584 studies was extracted, 8 of which were selected. One of them included women who had undergone a percutaneous biopsy with a histological diagnosis of radial scar/complex sclerosing lesion and subsequently underwent surgical excision; the results were used to assess the underestimation rate of atypical and malignant lesions.
Data synthesis
The overall underestimation rate in the 8 studies ranged from 1.3 to 40% and the invasive lesion underestimation rate varied from 0 to 10.5%.
Conclusion
The histopathological diagnosis of a radial scar/complex sclerosing lesion on the breast is not definitive, and it may underestimate atypical andmalignant lesions, which require a different treatment, making surgical excision an important step in diagnostic evaluation.
Views127This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleUnderestimation Rate in the Percutaneous Diagnosis of Radial Scar/Complex Sclerosing Lesion of the Breast: Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(1):67-73
02-28-2022- Ana Beatrice Bonganha Zanon ,
- Jonathan Yugo Maesaka ,
- Bruna Bello Chequin ,
- Ana Gabriela de Siqueira Santos ,
- Edmund Chada Baracat ,
- José Roberto Filassi
Views127See moreAbstract
Objective
To evaluate the underestimation rate in breast surgical biopsy after the diagnosis of radial scar/complex sclerosing lesion through percutaneous biopsy.
Data Sources
A systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. The PubMed, SciELO, Cochrane, and Embase databases were consulted, with searches conducted through November 2020, using specific keywords (radial scar OR complex sclerosing lesion, breast cancer, anatomopathological percutaneous biopsy AND/OR surgical biopsy).
Data collection
Study selection was conducted by two researchers experienced in preparing systematic reviews. The eight selected articles were fully read, and a comparative analysis was performed.
Study selection
A total of 584 studies was extracted, 8 of which were selected. One of them included women who had undergone a percutaneous biopsy with a histological diagnosis of radial scar/complex sclerosing lesion and subsequently underwent surgical excision; the results were used to assess the underestimation rate of atypical and malignant lesions.
Data synthesis
The overall underestimation rate in the 8 studies ranged from 1.3 to 40% and the invasive lesion underestimation rate varied from 0 to 10.5%.
Conclusion
The histopathological diagnosis of a radial scar/complex sclerosing lesion on the breast is not definitive, and it may underestimate atypical andmalignant lesions, which require a different treatment, making surgical excision an important step in diagnostic evaluation.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- Ana Beatrice Bonganha Zanon
-
Review Article
Deficiency and Insufficiency of Vitamin D in Women of Childbearing Age: A Systematic Review and Meta-analysis
- Rosa Camila Lucchetta ,
- Isabele Held Lemos ,
- Ana Luísa Rodriguez Gini ,
- Sophia de Andrade Cavicchioli ,
- Marcela Forgerini , [ ... ],
- Patricia de Carvalho Mastroianni
02-24-2022
Summary
Review ArticleDeficiency and Insufficiency of Vitamin D in Women of Childbearing Age: A Systematic Review and Meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(4):409-424
02-24-2022- Rosa Camila Lucchetta ,
- Isabele Held Lemos ,
- Ana Luísa Rodriguez Gini ,
- Sophia de Andrade Cavicchioli ,
- Marcela Forgerini ,
- Fabiana Rossi Varallo ,
- Mariane Nunes de Nadai ,
- Fernando Fernandez-Llimos ,
- Patricia de Carvalho Mastroianni
Views261Abstract
Objective
To estimate the prevalence of inadequate vitamin D level and its associated factors for women of childbearing age in Brazil.
Methods
A systematic reviewwas conducted (last updatedMay 2020).Meta-analyses were performed using the inverse-variance for fixed models with summary proportion calculation by Freeman-Tukey double arcsine. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies.
Results
Our review identified 31 studies, comprising 4,006 participants. All the studies had at least one weakness, mainly due to the use of convenience sampling and small sample size. The overall prevalence of vitamin D deficiency, insufficiency, and both deficiency and insufficiency were 35% (confidence interval, 95%CI: 34-37%), 42% (95%CI: 41-44%), and 72% (95%CI: 71-74%), respectively.
Conclusion
Although the magnitude of the prevalence of inadequate levels of vitamin D is uncertain, the evidence suggests that presence of vitamin D deficiency or insufficiency in women of reproductive age can cause moderate to severe problems.
Key-words cholecalciferolMaternal nutritionnutritional epidemiologyvitamin D deficiencyWomen's healthSee moreViews261This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleDeficiency and Insufficiency of Vitamin D in Women of Childbearing Age: A Systematic Review and Meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(4):409-424
02-24-2022- Rosa Camila Lucchetta ,
- Isabele Held Lemos ,
- Ana Luísa Rodriguez Gini ,
- Sophia de Andrade Cavicchioli ,
- Marcela Forgerini ,
- Fabiana Rossi Varallo ,
- Mariane Nunes de Nadai ,
- Fernando Fernandez-Llimos ,
- Patricia de Carvalho Mastroianni
Views261Abstract
Objective
To estimate the prevalence of inadequate vitamin D level and its associated factors for women of childbearing age in Brazil.
Methods
A systematic reviewwas conducted (last updatedMay 2020).Meta-analyses were performed using the inverse-variance for fixed models with summary proportion calculation by Freeman-Tukey double arcsine. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies.
Results
Our review identified 31 studies, comprising 4,006 participants. All the studies had at least one weakness, mainly due to the use of convenience sampling and small sample size. The overall prevalence of vitamin D deficiency, insufficiency, and both deficiency and insufficiency were 35% (confidence interval, 95%CI: 34-37%), 42% (95%CI: 41-44%), and 72% (95%CI: 71-74%), respectively.
Conclusion
Although the magnitude of the prevalence of inadequate levels of vitamin D is uncertain, the evidence suggests that presence of vitamin D deficiency or insufficiency in women of reproductive age can cause moderate to severe problems.
Key-words cholecalciferolMaternal nutritionnutritional epidemiologyvitamin D deficiencyWomen's healthSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Rosa Camila Lucchetta
-
Review Article
Prevalence of Preeclampsia in Brazil: An Integrative Review
- José Paulo de Siqueira Guida ,
- Beatriz Gadioli de Andrade ,
- Luis Gabriel Ferreira Pissinatti ,
- Bruna Fagundes Rodrigues ,
- Caio Augusto Hartman , [ ... ],
- Maria Laura Costa
02-09-2022
Summary
Review ArticlePrevalence of Preeclampsia in Brazil: An Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(7):686-691
02-09-2022- José Paulo de Siqueira Guida ,
- Beatriz Gadioli de Andrade ,
- Luis Gabriel Ferreira Pissinatti ,
- Bruna Fagundes Rodrigues ,
- Caio Augusto Hartman ,
- Maria Laura Costa
Views279See moreAbstract
Objective
To review literature and estimate the occurrence of preeclampsia and its complications in Brazil.
Methods
We performed an integrative review of the literature, and included observational studies published until August 2021 on the SciELO and PubMed databases that evaluated preeclampsia among pregnant women in Brazil. Other variables of interests were maternal death, neonatal death, hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, and eclampsia. Three independent reviewers evaluated all retrieved studies and selected those that met inclusion criteria. A metanalysis of the prevalence of preeclampsia and eclampsia was also performed, to estimate a pooled frequency of those conditions among the studies included.
Results
We retrieved 304 studies after the initial search; of those, 10 were included in the final analysis, with a total of 52,986 women considered. The pooled prevalence of preeclampsia was of 6.7%, with a total of 2,988 cases reported. The frequency of eclampsia ranged from 1.7% to 6.2%, while the occurrence of HELLP syndrome was underreported. Prematurity associated to hypertensive disorders ranged from 0.5% to 1.72%.
Conclusion
The frequency of preeclampsia was similar to that reported in other international studies, and it is increasing in Brazil, probably due to the adoption of new diagnostic criteria. The development of a national surveillance network would be essential to understand the problem of hypertensive disorders of pregnancy in Brazil.
Views279This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticlePrevalence of Preeclampsia in Brazil: An Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(7):686-691
02-09-2022- José Paulo de Siqueira Guida ,
- Beatriz Gadioli de Andrade ,
- Luis Gabriel Ferreira Pissinatti ,
- Bruna Fagundes Rodrigues ,
- Caio Augusto Hartman ,
- Maria Laura Costa
Views279See moreAbstract
Objective
To review literature and estimate the occurrence of preeclampsia and its complications in Brazil.
Methods
We performed an integrative review of the literature, and included observational studies published until August 2021 on the SciELO and PubMed databases that evaluated preeclampsia among pregnant women in Brazil. Other variables of interests were maternal death, neonatal death, hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, and eclampsia. Three independent reviewers evaluated all retrieved studies and selected those that met inclusion criteria. A metanalysis of the prevalence of preeclampsia and eclampsia was also performed, to estimate a pooled frequency of those conditions among the studies included.
Results
We retrieved 304 studies after the initial search; of those, 10 were included in the final analysis, with a total of 52,986 women considered. The pooled prevalence of preeclampsia was of 6.7%, with a total of 2,988 cases reported. The frequency of eclampsia ranged from 1.7% to 6.2%, while the occurrence of HELLP syndrome was underreported. Prematurity associated to hypertensive disorders ranged from 0.5% to 1.72%.
Conclusion
The frequency of preeclampsia was similar to that reported in other international studies, and it is increasing in Brazil, probably due to the adoption of new diagnostic criteria. The development of a national surveillance network would be essential to understand the problem of hypertensive disorders of pregnancy in Brazil.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - José Paulo de Siqueira Guida
-
Review Article
Main Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review
- Camilla Olivares Figueira ,
- Fernanda Garanhani Surita ,
- Kleber Fertrin ,
- Guilherme de Moraes Nobrega ,
- Maria Laura Costa
02-09-2022
Summary
Review ArticleMain Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(6):593-601
02-09-2022- Camilla Olivares Figueira ,
- Fernanda Garanhani Surita ,
- Kleber Fertrin ,
- Guilherme de Moraes Nobrega ,
- Maria Laura Costa
Views249See moreAbstract
Sickle cell disease (SCD) is the most common monogenic disease worldwide, with a variable prevalence in each continent. A single nucleotide substitution leads to an amino-acid change in the β-globin chain, altering the normal structure of hemoglobin, which is then called hemoglobin S inherited in homozygosity (HbSS) or double heterozygosity (HbSC, HbSβ), and leads to chronic hemolysis, vaso-occlusion, inflammation, and endothelium activation. Pregnant women with SCD are at a higher risk of developing maternal and perinatal complications. We performed a narrative review of the literature considering SCD and pregnancy, the main clinical and obstetrical complications, the specific antenatal care, and the follow-up for maternal and fetal surveillance. Pregnant women with SCD are at a higher risk of developing clinical and obstetric complications such as pain episodes, pulmonary complications, infections, thromboembolic events, preeclampsia, and maternal death. Their newborns are also at an increased risk of developing neonatal complications: fetal growth restriction, preterm birth, stillbirth. Severe complications can occur in patients of any genotype. We concluded that SCD is a high-risk condition that increases maternal and perinatal morbidity and mortality. A multidisciplinary approach during pregnancy and the postpartum period is key to adequately diagnose and treat complications.
Views249This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleMain Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(6):593-601
02-09-2022- Camilla Olivares Figueira ,
- Fernanda Garanhani Surita ,
- Kleber Fertrin ,
- Guilherme de Moraes Nobrega ,
- Maria Laura Costa
Views249See moreAbstract
Sickle cell disease (SCD) is the most common monogenic disease worldwide, with a variable prevalence in each continent. A single nucleotide substitution leads to an amino-acid change in the β-globin chain, altering the normal structure of hemoglobin, which is then called hemoglobin S inherited in homozygosity (HbSS) or double heterozygosity (HbSC, HbSβ), and leads to chronic hemolysis, vaso-occlusion, inflammation, and endothelium activation. Pregnant women with SCD are at a higher risk of developing maternal and perinatal complications. We performed a narrative review of the literature considering SCD and pregnancy, the main clinical and obstetrical complications, the specific antenatal care, and the follow-up for maternal and fetal surveillance. Pregnant women with SCD are at a higher risk of developing clinical and obstetric complications such as pain episodes, pulmonary complications, infections, thromboembolic events, preeclampsia, and maternal death. Their newborns are also at an increased risk of developing neonatal complications: fetal growth restriction, preterm birth, stillbirth. Severe complications can occur in patients of any genotype. We concluded that SCD is a high-risk condition that increases maternal and perinatal morbidity and mortality. A multidisciplinary approach during pregnancy and the postpartum period is key to adequately diagnose and treat complications.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Camilla Olivares Figueira
-
Review Article
Use of Corticosteroids in Prenatal Treatment of Congenital Pulmonary Adenomatoid Malformation: Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):304-310
02-02-2022
Summary
Review ArticleUse of Corticosteroids in Prenatal Treatment of Congenital Pulmonary Adenomatoid Malformation: Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):304-310
02-02-2022Views127Abstract
Objective
To review data on the use of corticosteroids for the treatment of fetuses with high-risk congenital pulmonary adenomatoid malformation (CPAM).
Methods
Integrative review based on the literature available onMEDLINE and LILACS, including articles published until November, 2020.
Results
The initial search resulted in 87 articles, 4 of which were selected for analysis, with all of them being retrospective descriptive observational studies. In the group of fetuses that received only a single corticosteroid cycle, the hydrops resolution rate was 70%, and the survival rate was 83.8%. In fetuses treated with 2 or more cycles of corticosteroids, there was an improvement in the condition of hydrops or edema in a single body compartment in 47%, and survival of 81.8% of the fetuses.
Conclusion
The use of corticosteroids for the prenatal treatment of high-risk CPAM appears to be associated with an improvement in perinatal outcomes.
Key-words Betamethasonecongenital pulmonary adenomatoid malformationcorticosteroidFetal treatmenthydropsSee moreViews127This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleUse of Corticosteroids in Prenatal Treatment of Congenital Pulmonary Adenomatoid Malformation: Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):304-310
02-02-2022Views127Abstract
Objective
To review data on the use of corticosteroids for the treatment of fetuses with high-risk congenital pulmonary adenomatoid malformation (CPAM).
Methods
Integrative review based on the literature available onMEDLINE and LILACS, including articles published until November, 2020.
Results
The initial search resulted in 87 articles, 4 of which were selected for analysis, with all of them being retrospective descriptive observational studies. In the group of fetuses that received only a single corticosteroid cycle, the hydrops resolution rate was 70%, and the survival rate was 83.8%. In fetuses treated with 2 or more cycles of corticosteroids, there was an improvement in the condition of hydrops or edema in a single body compartment in 47%, and survival of 81.8% of the fetuses.
Conclusion
The use of corticosteroids for the prenatal treatment of high-risk CPAM appears to be associated with an improvement in perinatal outcomes.
Key-words Betamethasonecongenital pulmonary adenomatoid malformationcorticosteroidFetal treatmenthydropsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article
Health of the Newborn and Breastfeeding during the COVID-19 Pandemic: A Literature Review
- Carmen Amelia Salvador-Pinos ,
- Edson Zangiacomi Martinez ,
- Susana Eulalia Dueñas-Matute ,
- Rosa Romero de Aguinaga ,
- Juan Carlos Jácome , [ ... ],
- Valheria Cárdenas-Morales
01-31-2022
Summary
Review ArticleHealth of the Newborn and Breastfeeding during the COVID-19 Pandemic: A Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):311-318
01-31-2022- Carmen Amelia Salvador-Pinos ,
- Edson Zangiacomi Martinez ,
- Susana Eulalia Dueñas-Matute ,
- Rosa Romero de Aguinaga ,
- Juan Carlos Jácome ,
- Stephanie Michelena-Tupiza ,
- Valheria Cárdenas-Morales
Views228See moreAbstract
Objective
The present article presents a literature review concerning the microbiota of breast milk and the influence of epigenetics in the susceptibility to COVID-19.
Methods
A literature review.
Results
Breastfeeding transfers microbiota, nutrients, diverse white blood cells, prebiotics, hormones, and antibodies to the baby, which provide short- and longterm immunological protection against several infectious, gastrointestinal, and respiratory illnesses. The little evidence available shows that breast milk very rarely carries the SARS-CoV-2 virus, and even in those cases, it has been discarded as the source of contagion.
Conclusion
The reviewed studies show evidence of a beneficial effect of breastfeeding and highlights its importance on the current pandemic due to the immune reinforcement that it provides. Breastfed individuals showed better clinical response due to the influence on the microbiota and to the nutritional and immune contribution provided by breast milk, compared with those who were not breastfed.
Views228This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleHealth of the Newborn and Breastfeeding during the COVID-19 Pandemic: A Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):311-318
01-31-2022- Carmen Amelia Salvador-Pinos ,
- Edson Zangiacomi Martinez ,
- Susana Eulalia Dueñas-Matute ,
- Rosa Romero de Aguinaga ,
- Juan Carlos Jácome ,
- Stephanie Michelena-Tupiza ,
- Valheria Cárdenas-Morales
Views228See moreAbstract
Objective
The present article presents a literature review concerning the microbiota of breast milk and the influence of epigenetics in the susceptibility to COVID-19.
Methods
A literature review.
Results
Breastfeeding transfers microbiota, nutrients, diverse white blood cells, prebiotics, hormones, and antibodies to the baby, which provide short- and longterm immunological protection against several infectious, gastrointestinal, and respiratory illnesses. The little evidence available shows that breast milk very rarely carries the SARS-CoV-2 virus, and even in those cases, it has been discarded as the source of contagion.
Conclusion
The reviewed studies show evidence of a beneficial effect of breastfeeding and highlights its importance on the current pandemic due to the immune reinforcement that it provides. Breastfed individuals showed better clinical response due to the influence on the microbiota and to the nutritional and immune contribution provided by breast milk, compared with those who were not breastfed.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Carmen Amelia Salvador-Pinos
Review Article Archives - Page 8 of 16 - Revista Brasileira de Ginecologia e Obstetrícia
