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Original Article
Association between Single Nucleotide Polymorphisms and Endometriosis in a Brazilian Population
- Paula Coelho Silva Viana
, - Ana Carolina Delgado Malvaccini Mendes ,
- Lucas Farah Delgado ,
- Gustavo Tostes ,
- Lidiane Gonçalves , [ ... ],
- Pamela Souza Almeida Silva Gerheim
04-22-2020
Summary
Original ArticleAssociation between Single Nucleotide Polymorphisms and Endometriosis in a Brazilian Population
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):146-151
04-22-2020- Paula Coelho Silva Viana ,
- Ana Carolina Delgado Malvaccini Mendes ,
- Lucas Farah Delgado ,
- Gustavo Tostes ,
- Lidiane Gonçalves ,
- Homero Gonçalves Júnior ,
- Nádia Rezende Barbosa Raposo ,
- Geraldo Sérgio Farinazzo Vitral ,
- Pamela Souza Almeida Silva Gerheim
Views249See moreAbstract
Objective
To investigate the association between genetic polymorphisms in candidate genes or candidate regions and the development of endometriosis in Brazilian women.
Methods
A total of 30 women between 25 and 64 years old with a diagnosis of endometriosis participated in the present study, as well as 30 matched control women from the same age group, asymptomatic and without family history of the disease. The patients genotypic and allelic frequencies of polymorphisms in the GREB1 gene (rs13394619) and in the intergenic region at position 7p15.2 (rs12700667) were analyzed and compared.
Results
There was no significant difference in the frequency of genotypes for the A > G polymorphism (rs13394619) in the GREB1 gene between the two groups. However, the distribution frequencies of the genotypes for the A > G polymorphism (rs12700667) in an intergenic region on chromosome 7 were different for control patients and for patients with endometriosis, with higher frequency of the AG genotype compared to the GG between patients with the disease (odds ratio [OR] = 3.49; confidence interval [CI] = 1.47–8.26).
Conclusion
The present study suggests that the polymorphism in the intergenic region of chromosome 7 is associated with the risk of developing endometriosis in a population of Brazilian women from Juiz de Fora.
Views249
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleAssociation between Single Nucleotide Polymorphisms and Endometriosis in a Brazilian Population
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):146-151
04-22-2020- Paula Coelho Silva Viana ,
- Ana Carolina Delgado Malvaccini Mendes ,
- Lucas Farah Delgado ,
- Gustavo Tostes ,
- Lidiane Gonçalves ,
- Homero Gonçalves Júnior ,
- Nádia Rezende Barbosa Raposo ,
- Geraldo Sérgio Farinazzo Vitral ,
- Pamela Souza Almeida Silva Gerheim
Views249See moreAbstract
Objective
To investigate the association between genetic polymorphisms in candidate genes or candidate regions and the development of endometriosis in Brazilian women.
Methods
A total of 30 women between 25 and 64 years old with a diagnosis of endometriosis participated in the present study, as well as 30 matched control women from the same age group, asymptomatic and without family history of the disease. The patients genotypic and allelic frequencies of polymorphisms in the GREB1 gene (rs13394619) and in the intergenic region at position 7p15.2 (rs12700667) were analyzed and compared.
Results
There was no significant difference in the frequency of genotypes for the A > G polymorphism (rs13394619) in the GREB1 gene between the two groups. However, the distribution frequencies of the genotypes for the A > G polymorphism (rs12700667) in an intergenic region on chromosome 7 were different for control patients and for patients with endometriosis, with higher frequency of the AG genotype compared to the GG between patients with the disease (odds ratio [OR] = 3.49; confidence interval [CI] = 1.47–8.26).
Conclusion
The present study suggests that the polymorphism in the intergenic region of chromosome 7 is associated with the risk of developing endometriosis in a population of Brazilian women from Juiz de Fora.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Paula Coelho Silva Viana
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Original Article
Junctional Zone in Infertile Women: A Three-dimensional Ultrasound Study
- Vanessa Silva ,
- Flávia Fundora Ramos ,
- Ana Filipa Matos Brás ,
- Ricardo Filipe Sousa Santos ,
- Maria Sofia Dantas Pinto Lobo Xavier, [ ... ],
- Rui Filipe Oliveira Miguelote
04-22-2020
Summary
Original ArticleJunctional Zone in Infertile Women: A Three-dimensional Ultrasound Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):152-159
04-22-2020- Vanessa Silva ,
- Flávia Fundora Ramos ,
- Ana Filipa Matos Brás ,
- Ricardo Filipe Sousa Santos ,
- Maria Sofia Dantas Pinto Lobo Xavier,
- Rui Filipe Oliveira Miguelote
Views179See moreAbstract
Objective
To analyze the interobserver and intraobserver reproducibility of the visualization and continuity of the juncional zone (JZ) by three-dimensional (3D) ultrasound in infertile women, and to evaluate the sociodemographic, hormonal, and structural factors that influence these assessments.
Methods
A prospective study conducted at the Assisted Reproductive Technology Unit of Hospital Senhora da Oliveira, in the city of Guimarães, Portugal. Transvaginal 3D ultrasonography was performed, and 2 volumes were generated per case. Two observers who were blinded to each other's work analyzed these volumes, choosing the best coronal section. Four months later, one of the observers performed the same methodology. The JZ visualization was classified as optimal, satisfactory, and unsatisfactory, and the JZ continuity, as continuous and discontinuous. The interobserver and intraobserver agreements were analyzed. The influence of hormonal, structural, and sociodemographic factors on the JZ was evaluated.
Results
In total, 65 women were included in the present study. The interobserver reproducibility was substantial for JZ visualization and continuity (k = 0.635 and 0.753 respectively), and the intraobserver reproducibility was very good for JZ visualization and continuity (k = 0.884 and 0.816 respectively). Trilaminar endometrial pattern was associated with optimal JZ visualization (p = 0.012). The increase of 1 unit in the level of serum estradiol represents a 9.9% decrease in the odds of unsatisfactory visualization of the JZ (odds ratio [OR] = 0.9; 95% confidence interval [95%CI] = 0.814–0.996; p = 0.042). Endometriosis increases the odds of unsatisfactory visualization by 24 times (OR = 23.7; 95%CI = 1.262–437.057; p = 0.034). The prevalence of discontinuous JZs was of 60%. Myomas and endometriosis were associated with discontinuous JZs (p = 0.034 and 0.016 respectively).
Conclusion
The assessment of JZ visualization and continuity by 3D ultrasound is reproducible enough to be used in the clinical practice.
Views179This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleJunctional Zone in Infertile Women: A Three-dimensional Ultrasound Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):152-159
04-22-2020- Vanessa Silva ,
- Flávia Fundora Ramos ,
- Ana Filipa Matos Brás ,
- Ricardo Filipe Sousa Santos ,
- Maria Sofia Dantas Pinto Lobo Xavier,
- Rui Filipe Oliveira Miguelote
Views179See moreAbstract
Objective
To analyze the interobserver and intraobserver reproducibility of the visualization and continuity of the juncional zone (JZ) by three-dimensional (3D) ultrasound in infertile women, and to evaluate the sociodemographic, hormonal, and structural factors that influence these assessments.
Methods
A prospective study conducted at the Assisted Reproductive Technology Unit of Hospital Senhora da Oliveira, in the city of Guimarães, Portugal. Transvaginal 3D ultrasonography was performed, and 2 volumes were generated per case. Two observers who were blinded to each other's work analyzed these volumes, choosing the best coronal section. Four months later, one of the observers performed the same methodology. The JZ visualization was classified as optimal, satisfactory, and unsatisfactory, and the JZ continuity, as continuous and discontinuous. The interobserver and intraobserver agreements were analyzed. The influence of hormonal, structural, and sociodemographic factors on the JZ was evaluated.
Results
In total, 65 women were included in the present study. The interobserver reproducibility was substantial for JZ visualization and continuity (k = 0.635 and 0.753 respectively), and the intraobserver reproducibility was very good for JZ visualization and continuity (k = 0.884 and 0.816 respectively). Trilaminar endometrial pattern was associated with optimal JZ visualization (p = 0.012). The increase of 1 unit in the level of serum estradiol represents a 9.9% decrease in the odds of unsatisfactory visualization of the JZ (odds ratio [OR] = 0.9; 95% confidence interval [95%CI] = 0.814–0.996; p = 0.042). Endometriosis increases the odds of unsatisfactory visualization by 24 times (OR = 23.7; 95%CI = 1.262–437.057; p = 0.034). The prevalence of discontinuous JZs was of 60%. Myomas and endometriosis were associated with discontinuous JZs (p = 0.034 and 0.016 respectively).
Conclusion
The assessment of JZ visualization and continuity by 3D ultrasound is reproducible enough to be used in the clinical practice.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Vanessa Silva
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Original Article
Use of Intensive Care Unit in Women with Severe Maternal Morbidity and Maternal Death: Results from a National Multicenter Study
- Fabiano M. Soares ,
- José Paulo Guida ,
- Rodolfo Carvalho Pacagnella ,
- João Paulo Souza ,
- Mary Ângela Parpinelli , [ ... ],
- José Guilherme Cecatti
04-22-2020
Summary
Original ArticleUse of Intensive Care Unit in Women with Severe Maternal Morbidity and Maternal Death: Results from a National Multicenter Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):124-132
04-22-2020- Fabiano M. Soares ,
- José Paulo Guida ,
- Rodolfo Carvalho Pacagnella ,
- João Paulo Souza ,
- Mary Ângela Parpinelli ,
- Samira Maerrawi Haddad ,
- José Guilherme Cecatti
Views193See moreAbstract
Objective
To assess the use of the intensive care unit (ICU) and its effect on maternal mortality (MM) among women with severe maternal morbidity (SMM).
Materials and Methods
A secondary analysis of a cross-sectional study on surveillance of SMM in 27 Brazilian obstetric referral centers. The analysis focused on the association between ICU use and maternal death according to individual characteristics and disease severity. Two multivariate regressions considering use of the ICU, age, ethnicity, adequacy of care and the human development index were performed to identify the factors associated to maternal death and maternal near-miss.
Results
Out of 82,388 deliveries during the period, there were 9,555 (11.6%) women with SMM, and the MM ratio was of 170.4/100 thousand live births. In total, 8,135 (85.1%) patients were managed in facilities in which ICUs were available; however, only 2,059 (25.3%) had been admitted to the ICU. On the multivariate analysis, when the severity of the maternal disease was measured by the maternal severity score (MMS), the strength of the association between the use of the ICU and maternal death was greatly reduced, along with inadequate care and non-availability of the ICU at the facility. On the assessment of only the more critical cases (SMO, severe maternal outcome), the same pattern of association between ICU and MM was observed. In the models used, only inadequate care and MSS were significantly associated with MM.
Conclusion
The current study indicates that the main variables associated with maternal death are the severity and adequacy of the case management, which is more frequent in ICU admissions. The use of the ICU without the stratification of the patients by severity may not produce the expected benefits for part of the women.
Views193This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleUse of Intensive Care Unit in Women with Severe Maternal Morbidity and Maternal Death: Results from a National Multicenter Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):124-132
04-22-2020- Fabiano M. Soares ,
- José Paulo Guida ,
- Rodolfo Carvalho Pacagnella ,
- João Paulo Souza ,
- Mary Ângela Parpinelli ,
- Samira Maerrawi Haddad ,
- José Guilherme Cecatti
Views193See moreAbstract
Objective
To assess the use of the intensive care unit (ICU) and its effect on maternal mortality (MM) among women with severe maternal morbidity (SMM).
Materials and Methods
A secondary analysis of a cross-sectional study on surveillance of SMM in 27 Brazilian obstetric referral centers. The analysis focused on the association between ICU use and maternal death according to individual characteristics and disease severity. Two multivariate regressions considering use of the ICU, age, ethnicity, adequacy of care and the human development index were performed to identify the factors associated to maternal death and maternal near-miss.
Results
Out of 82,388 deliveries during the period, there were 9,555 (11.6%) women with SMM, and the MM ratio was of 170.4/100 thousand live births. In total, 8,135 (85.1%) patients were managed in facilities in which ICUs were available; however, only 2,059 (25.3%) had been admitted to the ICU. On the multivariate analysis, when the severity of the maternal disease was measured by the maternal severity score (MMS), the strength of the association between the use of the ICU and maternal death was greatly reduced, along with inadequate care and non-availability of the ICU at the facility. On the assessment of only the more critical cases (SMO, severe maternal outcome), the same pattern of association between ICU and MM was observed. In the models used, only inadequate care and MSS were significantly associated with MM.
Conclusion
The current study indicates that the main variables associated with maternal death are the severity and adequacy of the case management, which is more frequent in ICU admissions. The use of the ICU without the stratification of the patients by severity may not produce the expected benefits for part of the women.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Fabiano M. Soares
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Original Article
The Role of Ischemia-modified Albumin as a Biomarker in Preeclampsia
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):133-139
04-22-2020
Summary
Original ArticleThe Role of Ischemia-modified Albumin as a Biomarker in Preeclampsia
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):133-139
04-22-2020Views133See moreAbstract
Objective
Ischemia-modified albumin (IMA)is a modified type of albumin protein that is formed under oxidative stress. This study aims to compare the levels of serum IMA between normotensive and preeclamptic pregnancies and to evaluate the relationship between the severity of the disease.
Methods
A total of 90 pregnant women aged between 18 and 45 years participated in this cross-sectional study. The levels of serum IMA were measured by enzyme-linked immunosorbent assay in 30 preeclamptic pregnant women with the severe signs of the disease, 30 preeclamptic pregnant women, and 30 normotensive pregnant women.. The study was designed as a cross-sectional clinical study.
Results
When the demographic characteristics were examined, statistically significant differences were found between the groups in terms of age, gestational week at birth and blood pressure. Age was higher in the preeclampsia with signs of severity group than in the normotensive group (p = 0.033). Pregnancy week was significantly the lowest in the preeclampsia with the severity signs group (p = 0.004). In normotensive patients, IMA levels were lower than in the preeclampsia groups (p = 0.001) but there was no significant difference in terms of severity of disease (p = 0.191). According to laboratory data; only the creatinine level was significantly different between the groups.
Conclusion
The levels of serum IMA were higher in patients with preeclampsia than in healthy pregnancies. However, there was no significant correlation in terms of preeclampsia severity; more extensive, prospective and long-term studies are needed.
Views133This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleThe Role of Ischemia-modified Albumin as a Biomarker in Preeclampsia
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):133-139
04-22-2020Views133See moreAbstract
Objective
Ischemia-modified albumin (IMA)is a modified type of albumin protein that is formed under oxidative stress. This study aims to compare the levels of serum IMA between normotensive and preeclamptic pregnancies and to evaluate the relationship between the severity of the disease.
Methods
A total of 90 pregnant women aged between 18 and 45 years participated in this cross-sectional study. The levels of serum IMA were measured by enzyme-linked immunosorbent assay in 30 preeclamptic pregnant women with the severe signs of the disease, 30 preeclamptic pregnant women, and 30 normotensive pregnant women.. The study was designed as a cross-sectional clinical study.
Results
When the demographic characteristics were examined, statistically significant differences were found between the groups in terms of age, gestational week at birth and blood pressure. Age was higher in the preeclampsia with signs of severity group than in the normotensive group (p = 0.033). Pregnancy week was significantly the lowest in the preeclampsia with the severity signs group (p = 0.004). In normotensive patients, IMA levels were lower than in the preeclampsia groups (p = 0.001) but there was no significant difference in terms of severity of disease (p = 0.191). According to laboratory data; only the creatinine level was significantly different between the groups.
Conclusion
The levels of serum IMA were higher in patients with preeclampsia than in healthy pregnancies. However, there was no significant correlation in terms of preeclampsia severity; more extensive, prospective and long-term studies are needed.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article
Description of Referrals for Colposcopy in a Hospital in Brazil
- Stephanie Hein de Carvalho ,
- Dayana Aparecida Nacimento Rosa ,
- André Luis Ferreira Santos ,
- Andréa Paula Peneluppi de Medeiros
04-22-2020
Summary
Original ArticleDescription of Referrals for Colposcopy in a Hospital in Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):140-145
04-22-2020- Stephanie Hein de Carvalho ,
- Dayana Aparecida Nacimento Rosa ,
- André Luis Ferreira Santos ,
- Andréa Paula Peneluppi de Medeiros
Views157See moreAbstract
Objective
To describe the referral for colposcopy in a Hospital in Brazil and the relative frequency of patients who benefited from it, considering the correct indications for the examination and its final diagnoses.
Methods
A retrospective study was performed in the colposcopy service database of the Hospital Universitário de Taubaté, Taubaté, state of São Paulo, Brazil. The frequency validated in the analysis of the medical records of women referred for clinical indication or cytological alteration, attended from March 2015 to March 2017. The population selected and analyzed included 256 results that were correlated to the cytological, clinical data and the result of the colposcopy.
Results
Of the women referred, 45% presented out of the age of screening according to the guidelines of cervical cancer screening, 8.6% being adolescents and young adults < 25 years old, and 36.4% of the patients being ≥ 65 years old. A total of 50% of the patients had no indication of colposcopy, that is, normal cytologies, benign changes, ectopia, cervicitis, atypical squamous cells of indeterminate significance (ASC-US) and low-grade intraepithelial lesion (LSIL) without persistence and normal clinical appearance. A total of 39.84% who underwent colposcopy had high-grade lesion or cancer results, thus benefiting from the adequate referral.
Conclusion
Most (60.16%) of the patients referred to the colposcopy service did not benefit from the referral for results without changes, such as negative colposcopies, histologies with no cervical intraepithelial neoplasm (CIN) or only CIN 1, or were out of the age for screening. These findings therefore demonstrate a significant number of unnecessary and inadequate referrals.
Views157This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleDescription of Referrals for Colposcopy in a Hospital in Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(3):140-145
04-22-2020- Stephanie Hein de Carvalho ,
- Dayana Aparecida Nacimento Rosa ,
- André Luis Ferreira Santos ,
- Andréa Paula Peneluppi de Medeiros
Views157See moreAbstract
Objective
To describe the referral for colposcopy in a Hospital in Brazil and the relative frequency of patients who benefited from it, considering the correct indications for the examination and its final diagnoses.
Methods
A retrospective study was performed in the colposcopy service database of the Hospital Universitário de Taubaté, Taubaté, state of São Paulo, Brazil. The frequency validated in the analysis of the medical records of women referred for clinical indication or cytological alteration, attended from March 2015 to March 2017. The population selected and analyzed included 256 results that were correlated to the cytological, clinical data and the result of the colposcopy.
Results
Of the women referred, 45% presented out of the age of screening according to the guidelines of cervical cancer screening, 8.6% being adolescents and young adults < 25 years old, and 36.4% of the patients being ≥ 65 years old. A total of 50% of the patients had no indication of colposcopy, that is, normal cytologies, benign changes, ectopia, cervicitis, atypical squamous cells of indeterminate significance (ASC-US) and low-grade intraepithelial lesion (LSIL) without persistence and normal clinical appearance. A total of 39.84% who underwent colposcopy had high-grade lesion or cancer results, thus benefiting from the adequate referral.
Conclusion
Most (60.16%) of the patients referred to the colposcopy service did not benefit from the referral for results without changes, such as negative colposcopies, histologies with no cervical intraepithelial neoplasm (CIN) or only CIN 1, or were out of the age for screening. These findings therefore demonstrate a significant number of unnecessary and inadequate referrals.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Stephanie Hein de Carvalho
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Original Article
Gestational Diabetes in the Population Served by Brazilian Public Health Care. Prevalence and Risk Factors
- Pâmela Antoniazzi dos Santos ,
- José Mauro Madi ,
- Emerson Rodrigues da Silva ,
- Daiane de Oliveira Pereira Vergani ,
- Breno Fauth de Araújo , [ ... ],
- Rosa Maria Rahmi Garcia
03-27-2020
Summary
Original ArticleGestational Diabetes in the Population Served by Brazilian Public Health Care. Prevalence and Risk Factors
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):12-18
03-27-2020- Pâmela Antoniazzi dos Santos ,
- José Mauro Madi ,
- Emerson Rodrigues da Silva ,
- Daiane de Oliveira Pereira Vergani ,
- Breno Fauth de Araújo ,
- Rosa Maria Rahmi Garcia
Views258See moreAbstract
Objective
To assess the prevalence of gestational diabetes mellitus and the main associated risk factors in the population served by the Brazilian Unified Health System in the city of Caxias do Sul, state of Rio Grande do Sul.
Materials and Methods
A descriptive, cross-sectional and retrospective study was conducted. Maternal variables were collected from the medical records of all pregnant women treated at the basic health units in 2016. Hyperglycemia during pregnancy (pregestational diabetes, overt diabetes and gestational diabetes mellitus) was identified by analyzing the results of a 75-g oral glucose tolerance test, as recommended by the Brazilian Ministry of Health. Based on the data, the women were allocated into two groups: the gestational diabetes group and the no gestational diabetes group.
Results
The estimated prevalence of gestational diabetes among 2,313 pregnant women was of 5.4% (95% confidence interval [95%CI]: 4.56-6.45). Pregnant women with 3 or more pregnancies had twice the odds of having gestational diabetes compared with primiparous women (odds ratio [OR]=2.19; 95%CI: 1.42-3.37; p<0.001). Pregnant women aged 35 years or older had three times the odds of having gestational diabetes when compared with younger women (OR=3.01; 95%CI: 1.97-4.61; p<0.001). Overweight pregnant women were 84% more likely to develop gestational diabetes than those with a body mass index lower than 25 kg/m2 (OR =1.84; 95%CI: 1.25-2.71; p=0.002). A multivariable regression analysis showed that being overweight and being 35 years old or older were independent variables.
Conclusion
In this population, the prevalence of gestational diabetes mellitus was of 5.4%. Age and being overweight were predictive factors for gestational diabetes.
Views258This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleGestational Diabetes in the Population Served by Brazilian Public Health Care. Prevalence and Risk Factors
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):12-18
03-27-2020- Pâmela Antoniazzi dos Santos ,
- José Mauro Madi ,
- Emerson Rodrigues da Silva ,
- Daiane de Oliveira Pereira Vergani ,
- Breno Fauth de Araújo ,
- Rosa Maria Rahmi Garcia
Views258See moreAbstract
Objective
To assess the prevalence of gestational diabetes mellitus and the main associated risk factors in the population served by the Brazilian Unified Health System in the city of Caxias do Sul, state of Rio Grande do Sul.
Materials and Methods
A descriptive, cross-sectional and retrospective study was conducted. Maternal variables were collected from the medical records of all pregnant women treated at the basic health units in 2016. Hyperglycemia during pregnancy (pregestational diabetes, overt diabetes and gestational diabetes mellitus) was identified by analyzing the results of a 75-g oral glucose tolerance test, as recommended by the Brazilian Ministry of Health. Based on the data, the women were allocated into two groups: the gestational diabetes group and the no gestational diabetes group.
Results
The estimated prevalence of gestational diabetes among 2,313 pregnant women was of 5.4% (95% confidence interval [95%CI]: 4.56-6.45). Pregnant women with 3 or more pregnancies had twice the odds of having gestational diabetes compared with primiparous women (odds ratio [OR]=2.19; 95%CI: 1.42-3.37; p<0.001). Pregnant women aged 35 years or older had three times the odds of having gestational diabetes when compared with younger women (OR=3.01; 95%CI: 1.97-4.61; p<0.001). Overweight pregnant women were 84% more likely to develop gestational diabetes than those with a body mass index lower than 25 kg/m2 (OR =1.84; 95%CI: 1.25-2.71; p=0.002). A multivariable regression analysis showed that being overweight and being 35 years old or older were independent variables.
Conclusion
In this population, the prevalence of gestational diabetes mellitus was of 5.4%. Age and being overweight were predictive factors for gestational diabetes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Pâmela Antoniazzi dos Santos
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Original Article
Self-care and Health Care in Postpartum Women with Obesity: A Qualitative Study
- Débora Bicudo Faria-Schützer ,
- Fernanda Garanhani Surita ,
- Larissa Rodrigues ,
- Daiane Sofia de Morais Paulino ,
- Egberto Ribeiro Turato
03-27-2020
Summary
Original ArticleSelf-care and Health Care in Postpartum Women with Obesity: A Qualitative Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):19-25
03-27-2020- Débora Bicudo Faria-Schützer ,
- Fernanda Garanhani Surita ,
- Larissa Rodrigues ,
- Daiane Sofia de Morais Paulino ,
- Egberto Ribeiro Turato
Views100See moreAbstract
Objective
To explore the experiences of women with obesity regarding self-care and the care provided by their families and health team after childbirth.
Methods
A clinical qualitative study performed at the Postnatal Outpatient Clinic of Hospital da Mulher, Universidade Estadual de Campinas, Brazil. The sample was selected using the saturation criteria, with 16 women with obesity up to 6 months after childbirth.
Results
The analysis comprised three categories: 1) postnatal self-care; 2) family support for woman after childbirth; and 3) postnatal health care service for women with obesity.
Conclusion
Women with obesity need support from the health team and from their families after childbirth, when they are overwhelmed by the exhausting care for the newborn. The present study reveals how important it is for health care professionals to broaden their perception and care provided after childbirth for women with obesity so they may experience an improvement in their quality of health and of life.
Views100This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleSelf-care and Health Care in Postpartum Women with Obesity: A Qualitative Study
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):19-25
03-27-2020- Débora Bicudo Faria-Schützer ,
- Fernanda Garanhani Surita ,
- Larissa Rodrigues ,
- Daiane Sofia de Morais Paulino ,
- Egberto Ribeiro Turato
Views100See moreAbstract
Objective
To explore the experiences of women with obesity regarding self-care and the care provided by their families and health team after childbirth.
Methods
A clinical qualitative study performed at the Postnatal Outpatient Clinic of Hospital da Mulher, Universidade Estadual de Campinas, Brazil. The sample was selected using the saturation criteria, with 16 women with obesity up to 6 months after childbirth.
Results
The analysis comprised three categories: 1) postnatal self-care; 2) family support for woman after childbirth; and 3) postnatal health care service for women with obesity.
Conclusion
Women with obesity need support from the health team and from their families after childbirth, when they are overwhelmed by the exhausting care for the newborn. The present study reveals how important it is for health care professionals to broaden their perception and care provided after childbirth for women with obesity so they may experience an improvement in their quality of health and of life.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Débora Bicudo Faria-Schützer
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Original Article
Construct and Criterion Validity of the Postmenopause Sexuality Questionnaire – PMSQ
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):26-34
03-27-2020
Summary
Original ArticleConstruct and Criterion Validity of the Postmenopause Sexuality Questionnaire – PMSQ
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):26-34
03-27-2020Views43See moreAbstract
Objective
To assess the construct and criterion validity of the Postmenopause Sexuality Questionnaire (PMSQ).
Methods
The present methodological questionnaire validation study included postmenopausal women. The construct validity was tested by factor analysis and the criterion validity was performed using the correlation between the PMSQ and the Female Sexual Function Index (FSFI). The ROC curve was used to verify sensitivity, specificity and to determine the cutoff point of the PMSQ.
Results
A total of 181 women with amean age of 56.4 ± 5.7 years old were evaluated. The exploratory factor analysis showed that the PMSQ presented Kaiser test = 0.88 and χ2 = 3293.7 (p < 0.001), commonalities ≥ 0.5, and extraction of 9 factors with eigenvalue ≥ 1; explaining 66.3% of the total variance. The PMSQ presented factor loadings between 0.4 and 0.8. A strong correlation between the 2 questionnaires (r = 0.79; p = 0.000) was shown. The cutoff point of the PMSQ was ≤ 55.5, assuming 87.9% sensitivity and 78.9% specificity (p < 0.001).
Conclusion
Since the PMSQ showed a strong correlation with the FSFI questionnaire, it presented good psychometric properties to assess the sexuality in postmenopausal women. Based on these results, the PMSQ could be widely tested as a specific instrument to examine the sexual function in postmenopausal women. Future studies, designed to examine the PMSQ instrument in different populations, are needed.
Views43This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleConstruct and Criterion Validity of the Postmenopause Sexuality Questionnaire – PMSQ
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(1):26-34
03-27-2020Views43See moreAbstract
Objective
To assess the construct and criterion validity of the Postmenopause Sexuality Questionnaire (PMSQ).
Methods
The present methodological questionnaire validation study included postmenopausal women. The construct validity was tested by factor analysis and the criterion validity was performed using the correlation between the PMSQ and the Female Sexual Function Index (FSFI). The ROC curve was used to verify sensitivity, specificity and to determine the cutoff point of the PMSQ.
Results
A total of 181 women with amean age of 56.4 ± 5.7 years old were evaluated. The exploratory factor analysis showed that the PMSQ presented Kaiser test = 0.88 and χ2 = 3293.7 (p < 0.001), commonalities ≥ 0.5, and extraction of 9 factors with eigenvalue ≥ 1; explaining 66.3% of the total variance. The PMSQ presented factor loadings between 0.4 and 0.8. A strong correlation between the 2 questionnaires (r = 0.79; p = 0.000) was shown. The cutoff point of the PMSQ was ≤ 55.5, assuming 87.9% sensitivity and 78.9% specificity (p < 0.001).
Conclusion
Since the PMSQ showed a strong correlation with the FSFI questionnaire, it presented good psychometric properties to assess the sexuality in postmenopausal women. Based on these results, the PMSQ could be widely tested as a specific instrument to examine the sexual function in postmenopausal women. Future studies, designed to examine the PMSQ instrument in different populations, are needed.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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