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Resumos de Teses
Avaliação do Tratamento Não-Medicamentoso (Orientação Verbal) das Mastalgias Cíclicas
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):459-459
10-03-2000
Views44This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesAvaliação do Tratamento Não-Medicamentoso (Orientação Verbal) das Mastalgias Cíclicas
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):459-459
10-03-2000DOI 10.1590/S0100-72032000000700010
Views44Avaliação do Tratamento Não-Medicamentoso (Orientação Verbal) das Mastalgias Cíclicas […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Relato de Caso
Angiosarcoma of the Breast: Case Report
- Renata Silva de Oliveira Viviani,
- Luiz Henrique Gebrim,
- Afonso Celso Pinto Nazário,
- Cláudio Kemp,
- Geraldo Rodrigues Lima
10-03-2000
Views94This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Relato de CasoAngiosarcoma of the Breast: Case Report
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):455-458
10-03-2000DOI 10.1590/S0100-72032000000700009
- Renata Silva de Oliveira Viviani,
- Luiz Henrique Gebrim,
- Afonso Celso Pinto Nazário,
- Cláudio Kemp,
- Geraldo Rodrigues Lima
Views94Primary angiosarcoma of the breast is a rare tumor, which appears between 14 and 82 years, with an average of 35 years of age. Its predominant clinical aspect is a painful mass with diffuse increase in the breast and violet or blackened color. Equally to other cases of sarcoma, the medium size of the lesion is approximately 5 cm at the diagnosis. Histologically, it is characterized by the proliferation of endothelial cells that form vascular channels linked to each other infiltrating glandular structures and fatty tissue. Its histological diagnosis is difficult and not always the right diagnosis is immediately established, mainly in the cases of a low malignancy degree, due to limited biopsy material. Because of the difficult diagnosis and aggressivity, it is a neoplasia with ominous prognosis, due to frequent metastasis. In our service, a 18-year-old patient presented with a painful lump which grew quickly. It was biopsied and a hemangioma was diagnosed, a wide excision being indicated. Three months later, she suffered a tumoral relapse, that was biopsied again and mastectomy was indicated, because it was an angiosarcoma with low degree of malignancy. After other relapses, chemotherapy was indicated and later, radiotherapy. During radiotherapy she developed new metastases, and died of pulmonary metastasis.
Key-words Breast neoplasmsSarcomaSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Prognostic Indicators In Lymph Node-Negative Breast Cancer: Estrogen Receptor and P53 and c-erbB-2 Protein Expression
- Adriana Harter Teixeira Bolaséll,
- Cláudio Galleano Zettler,
- Jeferson Vinholes,
- Simone Márcia Machado,
- Cláudia Kliemann
10-03-2000
Views114This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisPrognostic Indicators In Lymph Node-Negative Breast Cancer: Estrogen Receptor and P53 and c-erbB-2 Protein Expression
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):449-454
10-03-2000DOI 10.1590/S0100-72032000000700008
- Adriana Harter Teixeira Bolaséll,
- Cláudio Galleano Zettler,
- Jeferson Vinholes,
- Simone Márcia Machado,
- Cláudia Kliemann
Views114See morePurpose: to evaluate the prognostic value of estrogen receptor and p53 and c-erbB-2 proteins in lymph node-negative breast cancer. Methods: an immunohistochemical study was made in paraffin-embedded tissues from the file of the Instituto de Pesquisas Cito-Oncológicas of the Fundação Faculdade Federal de Ciências Médicas de Porto Alegre of fifty cases of postmenopausal women, who were treated at the Irmandade da Santa Casa de Misericórdia de Porto Alegre and at the Santa Rita Hospital from 1990 to 1994. For statistical analysis c² with Yates correction, as well as exact Fisher tests were used and Kaplan Meier curves compared with log-rank test. The mean follow-up of the patients was 3.6 years (3.1-4.5). Of the 50 cases, 14 showed recurrence during the period of follow-up. Results: the mean age was 61 years (46-78). Modified radical mastectomy was performed in 35 patients (70%) and 15 (30%) were submitted to lumpectomy/axillary dissection and postoperative radiation therapy. Fifty percent of the patients who showed recurrence did it in the first three years after the diagnosis. The mean size of the tumor was 2.8 cm (1.98-3.13) and the most frequent histological type was invasive ductal carcinoma of no special type (92%), according to the Bloom and Richardson graduation, 3 being stage I (6.6%), 35 stage II (76%) and 8 stage III (17.4%). In the tumors with recurrence, there was no grade I, 9 stage II (25.7%) and 3 stage III (37.5%). In relation to the prognosis, the disease-free interval was less when there was association of a poorly differentiated tumor with negative estrogen receptor (p = 0.006), positive p53 (p = 0.006) and positive c-erbB-2 (p = 0.001). Conclusion: postmenopausal women with lymph node-negative breast cancer showed worse prognosis in relation to disease-free interval when they presented poorly differentiated tumor associated with negative estrogen receptor, positive p53 and positive c-erbB-2.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Factors Related to Obesity and Android Pattern of Body Fat Distribution in Climacteric Women
- Diana Beatriz Filip Raskin,
- Aarão Mendes Pinto-Neto,
- Lúcia Helena Simões Costa Paiva,
- Analisa Raskin,
- Edson Zangiacomi Martinez
10-03-2000
Views103PlumX Metrics- Citations
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisFactors Related to Obesity and Android Pattern of Body Fat Distribution in Climacteric Women
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):435-441
10-03-2000DOI 10.1590/S0100-72032000000700006
- Diana Beatriz Filip Raskin,
- Aarão Mendes Pinto-Neto,
- Lúcia Helena Simões Costa Paiva,
- Analisa Raskin,
- Edson Zangiacomi Martinez
Views103See morePurpose: to describe sociodemographic characteristics of a group of climacteric women in order to discover the frequency and the variables associated with obesity and android profile of body fat distribution. Methods: an observational study was carried out in 518 patients aged 45 to 65 years, in a climacterium outpatient clinic. Age, color, menopausal status, duration of menopause, physical activity, smoking status, diet, alcohol intake, personal and family antecedents of arterial hypertension, diabetes mellitus, cardiovascular disease, dyslipidemia and obesity were considered. Body mass index and the waist/hip ratio were the dependent variables. For the statistical analysis Wilcoxon test, Pearson’s correlation coefficient, with a 5% level of significance, and multivariate analysis using regression model were used. Results: more than two thirds of the participants were nonobese with an android profile and postmenopausal. One fourth had physical activity and were smokers; half reported an inadequate diet and one fifth were alcoholics. Patients with an android profile presented higher mean age than women with gynecoid pattern. Personal antecedents of obesity, arterial hypertension, diabetes and family history of diabetes were related to obesity and android pattern. Postmenopausal status was significantly associated with the android profile. Conclusions: the majority of the participants were nonobese with an android profile, white, postmenopausal, sedentary, neither smokers nor alcoholics. The main factors related to obesity and android pattern were personal antecedents of obesity, arterial hypertension, diabetes, family history of diabetes and particularly, postmenopausal status with android profile.
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Gastroschisis: Prenatal Evaluation of Prognostic Factors for Postnatal Outcome
- Liliana Patroni,
- Maria de Lourdes Brizot,
- Samir A. Mustafá,
- Mário H.B. Carvalho,
- Marcos Marquês Silva, [ … ],
- Marcelo Zugaib
10-03-2000
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisGastroschisis: Prenatal Evaluation of Prognostic Factors for Postnatal Outcome
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):421-428
10-03-2000DOI 10.1590/S0100-72032000000700004
- Liliana Patroni,
- Maria de Lourdes Brizot,
- Samir A. Mustafá,
- Mário H.B. Carvalho,
- Marcos Marquês Silva,
- Seyzo Miyadahira,
- Marcelo Zugaib
Views68See morePurpose: to evaluate 24 cases of gastroschisis, in relation to the prognostic factors that interfered with postnatal outcome. Patients and Method: twenty-four pregnancies with fetal prenatal ultrasound diagnosis of gastroschisis, during an 8-year period, were analyzed. Gastroschisis was classified into isolated, when there were no other structural abnormalities, or associated, when other abnormalities were present. For both groups the following parameters were examined: ultrasound bowel dilatation (>18 mm), obstetric complications and postnatal outcome. Nonparametric Mann-Whitney and exact Fisher’s tests were used for statistical analyses. Results: in 9 cases (37.5%) gastroschisis was associated with other abnormalities, and in 15 cases it was isolated (62.5%). All cases of associated gastroschisis had a letal prognosis, therefore the overall mortality rate was 60.8%. In the group of isolated gastroschisis, all were born alive and were submitted to surgery, but the survival rate after surgical correction was 60%. The median gestational age at birth was 35 weeks and birth weight 2,365 grams. Premature delivery was observed in 10 cases, mainly as a consequence of obstetric complication. Two newborns were small for gestational age, and only 3 had birth weight >2,500 grams. Oligohydramnios was found in 46.6% and it was more frequent in the group of postnatal death (66.7%). Ultrasound assessment of bowel showed bowel dilatation in 86.6%, however, without relation to the prognosis and postnatal bowel findings. There was no significant difference between gestational age at birth and birth weight comparing the survivor and postnatal death groups. Conclusions: isolated gastroschisis had a better prognosis when compared to associated, therefore this prenatal differentiation is important. Isolated gastroschisis was often associated with prematurity, small birth weight and obstetric complications. Prenatal diagnosis allows better monitoring of fetal and obstetric conditions. Delivery should be at term, unless presenting with obstetric complications.
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Editorial
MAIS UMA META ATINGIDA
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):399-399
10-03-2000
Views59This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
EditorialMAIS UMA META ATINGIDA
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(7):399-399
10-03-2000This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Isoformas de Prolactina no Fluido Folicular de Pacientes Submetidas a FIV
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(10):658-658
07-23-2000
Views32This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesIsoformas de Prolactina no Fluido Folicular de Pacientes Submetidas a FIV
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(10):658-658
07-23-2000This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses
Avaliação Clínica e Urodinâmica de Mulheres com Instabilidade Vesical Antes e Após Eletro-estimulação Funcional do Assoalho Pélvico
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(10):658-658
07-23-2000
Views35This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Resumos de TesesAvaliação Clínica e Urodinâmica de Mulheres com Instabilidade Vesical Antes e Após Eletro-estimulação Funcional do Assoalho Pélvico
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(10):658-658
07-23-2000DOI 10.1590/S0100-72032000001000012
Views35Avaliação Clínica e Urodinâmica de Mulheres com Instabilidade Vesical Antes e Após Eletro-estimulação Funcional do Assoalho Pélvico[…]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article
Comparison of serum ischemia modified albumin levels between preeclamptic and healthy pregnant women
- Dinç Zuhal
,
- Çakar Erbil
,
- Kumru Pınar
,
- Erel Özcan
,
- Neşelioğlu Salim
,
[ … ], - Boz Gizem
01-23-2025
Summary
Original ArticleComparison of serum ischemia modified albumin levels between preeclamptic and healthy pregnant women
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo97
01-23-2025Views276See moreAbstract
Objective
Our aims to compare level of serum ischemia modified albümin(IMA) between healthy and preeclamptic pregnancies and to evaluate the relationship of IMA with preeclampsia, preeclampsia severity and perinatal outcomes.
Methods
Our study is a prospective case-control study. A total of 134 pregnant women (66 preeclamptic and 68 healthy pregnant) between 18-45 years of age and between 24- 41 gestational weeks participated. Serum IMA levels were measured by the Albumin Cobalt Binding (ACB) test.
Results
The mean IMA values were found to be significantly higher in the preeclampsia group compared to the control group (p<0,001). Patients were divided into 3 groups; severe preeclampsia(n=29), non-severe preeclampsia(n=37) and healthy pregnant(n=68). Statistically significant difference was not found between severe preeclampsia and non-severe preeclampsia (p=0.505). The performance of IMA values in predicting the development of preeclampsia among all participants was evaluated with Receiver Operating Characteristic (ROC) analysis. According to the ROC analysis, the best cut-off value at which the maximum area under the curve (AUC) was obtained was found when IMA>0.98(AUC: 0.690 95% Confidence Interval (CI): 0.600-0.781 p<0.001). When IMA threshold value of >0.98 was taken to predict preeclampsia; the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated as 65.15%, 64.71%, 64.18%, and 65.67%, respectively.
Conclusion
IMA level may be a useful new marker in recognizing and predicting preeclampsia. However, despite the power of recognizing the disease, serum IMA levels do not give an idea about the severity of the disease. More comprehensive studies are needed in order to use IMA levels in the diagnosis of preeclampsia.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Dinç Zuhal
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Original Article
Habits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
- Marcela Grigol Bardin
,
- Paulo César Giraldo
,
- Cristina Laguna Benetti-Pinto
,
- José Marcos Sanches
,
- Camila Carvalho de Araujo
,
[ … ], - Rose Luce Gomes do Amaral
04-08-2022
Views272This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleHabits of Genital Hygiene and Sexual Activity among Women with Bacterial Vaginosis and/or Vulvovaginal Candidiasis
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):169-177
04-08-2022- Marcela Grigol Bardin
,
- Paulo César Giraldo
,
- Cristina Laguna Benetti-Pinto
,
- José Marcos Sanches
,
- Camila Carvalho de Araujo
,
- Rose Luce Gomes do Amaral
Views272See moreAbstract
Objective
To evaluate genital hygiene among women with and without bacterial vaginosis (BV) and/or vulvovaginal candidiasis (VVC).
Methods
A cross-sectional study of reproductive-aged women who underwent gynecological and laboratory tests and fulfilled a genital hygiene questionnaire.
Results
This study evaluated 166 healthy controls and 141 women diagnosed with either BV (n=72), VVC (n=61), or both (n=8). The use of intimate soap and moist wipes after urination was more frequent among healthy women (p=0.042 and 0.032, respectively). Compared to controls, bactericidal soap was more used by women with BV (p=0.05).
Conclusion
Some hygiene habits were associated to BV and/or VVC. Clinical trials should address this important issue in women’s health.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Marcela Grigol Bardin
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FEBRASGO POSITION STATEMENT
Syphilis and pregnancy
- Geraldo Duarte
,
- Patrícia Pereira dos Santos Melli
,
- Angélica Espinosa Miranda
,
- Helaine Maria Besteti Pires Mayer Milanez
,
- Maria Luiza Menezes
,
[ … ], - Regis Kreitchmann
09-23-2024
Views270This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
FEBRASGO POSITION STATEMENTSyphilis and pregnancy
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS09
09-23-2024- Geraldo Duarte
,
- Patrícia Pereira dos Santos Melli
,
- Angélica Espinosa Miranda
,
- Helaine Maria Besteti Pires Mayer Milanez
,
- Maria Luiza Menezes
,
- Ana Gabriela Travassos
,
- Regis Kreitchmann
Views270See moreKey points
•Although congenital syphilis has a known etiological agent, accessible diagnosis and low-cost, effective treatment with low fetal toxicity, it continues to challenge obstetric and antenatal care services.
•The increasing rates of syphilis in the general population have direct repercussions on the increase in cases of congenital syphilis, a situation of objective interest for public health.
•Although transforming the recording of syphilis and congenital syphilis into notifiable diseases improved the records and has made it possible to measure the occurrence of these diseases and create solutions, no effects on reducing their frequency have been reached yet.
•The failure to control syphilis/congenital syphilis is multifactorial, and associates variables that range from the deficiency in teaching about these diseases in schools and in the training system of the various health professional segments, as well as the lack of rigid policies for quality control from antenatal care until the clinical follow-up of children exposed to Treponema pallidum during pregnancy.
•To date, benzathine penicillin is the only antimicrobial accepted as effective by the main health authorities on the planet for the treatment of syphilis in pregnant women.
•The fear of anaphylaxis in response to the treatment of syphilis with benzathine penicillin is an important factor hindering the prompt and correct treatment of pregnant women with syphilis, even though health authorities have made efforts to face the problem with solid arguments, still insufficient to resolve the question.
•Although specific protocols are published, the failure to control the treatment of syphilis in pregnant women is still observed with high frequency, indicating and reinforcing a failure in the quality control of these care principles.
The National Specialized Commission on Infectious Diseases of the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) endorses this document. Content production is based on scientific evidence on the proposed topic and the results presented contribute to clinical practice.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Geraldo Duarte
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Review Article
Mirabegron and Anticholinergics in the Treatment of Overactive Bladder Syndrome: A Meta-analysis
- Luisa Gracio Ferreira Sartori
,
- Bruno Monteiro Nunes
,
- Daniela Farah
,
- Leticia Maria de Oliveira
,
- Claudia Cristina Takano Novoa
,
[ … ], - Marcelo Cunio Machado Fonseca
08-04-2023
Views268This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleMirabegron and Anticholinergics in the Treatment of Overactive Bladder Syndrome: A Meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(6):337-346
08-04-2023- Luisa Gracio Ferreira Sartori
,
- Bruno Monteiro Nunes
,
- Daniela Farah
,
- Leticia Maria de Oliveira
,
- Claudia Cristina Takano Novoa
,
- Marair Gracio Ferreira Sartori
,
- Marcelo Cunio Machado Fonseca
Views268See moreAbstract
Objective
To compare the use of mirabegron with anticholinergics drugs for the treatment of overactive bladder (OB).
Data Source
Systematic searches were conducted in EMBASE, PUBMED, Cochrane, and LILACS databases from inception to September 2021. We included RCTs, women with clinically proven OB symptoms, studies that compared mirabegron to antimuscarinic drugs, and that evaluated the efficacy, safety or adherence.
Data Collection
RevMan 5.4 was used to combine results across studies. We derived risk ratios (RRs) and mean differences with 95% CIs using a random-effects meta-analytic model. Cochrane Collaboration Tool and GRADE was applied for risk of bias and quality of the evidence.
Data Synthesis
We included 14 studies with a total of 10,774 patients. Fewer total adverse events was reported in mirabegron group than in antimuscarinics group [RR 0.93 (0.89–0.98)]. The risk of gastrointestinal tract disorders and dry mouth were lower with mirabegron [RR 0,58 (0.48–0.68); 9375 patients; RR 0.44 (0.35–0.56), 9375 patients, respectively]. No difference was reported between mirabegron and antimuscarinics drugs for efficacy. The adherence to treatment was 87.7% in both groups [RR 0.99 (0.98–1.00)].
Conclusion
Mirabegron and antimuscarinics have comparable efficacy and adherence rates; however, mirabegron showed fewer total and isolated adverse events.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Luisa Gracio Ferreira Sartori
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Review Article
How can we reduce maternal mortality due to preeclampsia? The 4P rule
- Henri Augusto Korkes
,
- Ricardo Carvalho Cavalli
,
- Leandro Gustavo De Oliveira
,
- José Geraldo Lopes Ramos
,
- Sérgio Hofmeister de Almeida Martins Costa
,
[ … ], - Maria Laura Costa
06-03-2024
Views266This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleHow can we reduce maternal mortality due to preeclampsia? The 4P rule
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo43
06-03-2024- Henri Augusto Korkes
,
- Ricardo Carvalho Cavalli
,
- Leandro Gustavo De Oliveira
,
- José Geraldo Lopes Ramos
,
- Sérgio Hofmeister de Almeida Martins Costa
,
- Francisco Lázaro Pereira de Sousa
,
- Edson Vieira da Cunha Filho
,
- Maria Rita de Souza Mesquita
,
- Mário Dias Corrêa Júnior
,
- Ana Cristina Pinheiro Fernandes Araújo
,
- Alberto Carlos Moreno Zaconeta
,
- Carlos Henrique Esteves Freire
,
- Carlos Eduardo Poli de Figueiredo
,
- Edilberto Alves Pereira da Rocha Filho
,
- Nelson Sass
,
- José Carlos Peraçoli
,
- Maria Laura Costa
Views266See moreAbstract
In low and middle-income countries such as Brazil, most maternal deaths are related to hypertensive complications. Preeclampsia is the leading cause of maternal mortality and morbidity. Significant proportion is associated with the following factors: lack of identification of high-risk women, lack of adequate prevention, difficulty in maintaining a high-risk prenatal follow-up, delayed diagnosis, insecurity and low use of magnesium sulphate, delayed pregnancy interruption and lack of postpartum follow-up of these high-risk cases. Four major actions are proposed to minimize this alarming clinical picture and reduce the mortality rates due to preeclampsia, called the “4 P Rule” (Adequate Prevention – Vigilant Prenatal Care – Timely Delivery (Parturition) – Safe Postpartum). From this simple “rule” we can open a range of important processes and reminders that may help in the guidance of preeclampsia management.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Henri Augusto Korkes
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Review Article
Prevalence of Preeclampsia in Brazil: An Integrative Review
- José Paulo de Siqueira Guida
,
- Beatriz Gadioli de Andrade
,
- Luis Gabriel Ferreira Pissinatti
,
- Bruna Fagundes Rodrigues
,
- Caio Augusto Hartman
,
[ … ], - Maria Laura Costa
02-09-2022
Views261This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticlePrevalence of Preeclampsia in Brazil: An Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(7):686-691
02-09-2022- José Paulo de Siqueira Guida
,
- Beatriz Gadioli de Andrade
,
- Luis Gabriel Ferreira Pissinatti
,
- Bruna Fagundes Rodrigues
,
- Caio Augusto Hartman
,
- Maria Laura Costa
Views261See moreAbstract
Objective
To review literature and estimate the occurrence of preeclampsia and its complications in Brazil.
Methods
We performed an integrative review of the literature, and included observational studies published until August 2021 on the SciELO and PubMed databases that evaluated preeclampsia among pregnant women in Brazil. Other variables of interests were maternal death, neonatal death, hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, and eclampsia. Three independent reviewers evaluated all retrieved studies and selected those that met inclusion criteria. A metanalysis of the prevalence of preeclampsia and eclampsia was also performed, to estimate a pooled frequency of those conditions among the studies included.
Results
We retrieved 304 studies after the initial search; of those, 10 were included in the final analysis, with a total of 52,986 women considered. The pooled prevalence of preeclampsia was of 6.7%, with a total of 2,988 cases reported. The frequency of eclampsia ranged from 1.7% to 6.2%, while the occurrence of HELLP syndrome was underreported. Prematurity associated to hypertensive disorders ranged from 0.5% to 1.72%.
Conclusion
The frequency of preeclampsia was similar to that reported in other international studies, and it is increasing in Brazil, probably due to the adoption of new diagnostic criteria. The development of a national surveillance network would be essential to understand the problem of hypertensive disorders of pregnancy in Brazil.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - José Paulo de Siqueira Guida
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Review Article
Online scientific research on placentophagy: a bibliometric analysis
- Paloma Elisama de Oliveira Morais
,
- Melissa Santos Nassif
,
- Andreia Cristina Barbosa Costa
,
- Patrícia Scotini Freitas
,
- Rômulo Severo Sampaio
,
[ … ], - Isabelle Cristinne Pinto Costa
03-14-2024
Views260This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleOnline scientific research on placentophagy: a bibliometric analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo4
03-14-2024- Paloma Elisama de Oliveira Morais
,
- Melissa Santos Nassif
,
- Andreia Cristina Barbosa Costa
,
- Patrícia Scotini Freitas
,
- Rômulo Severo Sampaio
,
- Isabelle Cristinne Pinto Costa
Views260See moreAbstract
Objective:
To classify the bibliometric indicators of online scientific research on placentophagy.
Methods:
A bibliometric study was conducted to quantify the scientific production of authors and institutions with the aim of highlighting the growth and impact of these publications nationally and internationally. The Bradford Law, network maps, and textual statistics were used, with searches conducted in libraries and databases in October 2021.
Results:
The sample consisted of 64 articles, whose primary authors were associated with 49 institutions, and mostly with degrees in anthropology. The United States of America was the country that published the most papers on the theme, and most studies were reviews with individual production. Through the term analysis, it was found that the predominant themes regarding placentophagy were the following: Alternative therapy for women’s health, methodologies used for research in this area, period of placenta ingestion (postpartum period), and its benefits.
Conclusion:
The bibliometric indicators found are essential for the development of future research.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Paloma Elisama de Oliveira Morais
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Original Article
Cervical Cancer Screening with HPV Testing: Updates on the Recommendation
- Carla Fabrine Carvalho
,
- Julio Cesar Teixeira
,
- Joana Froes Bragança
,
- Sophie Derchain
,
- Luiz Carlos Zeferino
,
[ … ], - Diama Bhadra Vale
02-15-2022
Views259This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleCervical Cancer Screening with HPV Testing: Updates on the Recommendation
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):264-271
02-15-2022- Carla Fabrine Carvalho
,
- Julio Cesar Teixeira
,
- Joana Froes Bragança
,
- Sophie Derchain
,
- Luiz Carlos Zeferino
,
- Diama Bhadra Vale
Views259Abstract
The present update is a reassessment of the 2018 ‘Guidelines for HPV-DNA Testing for Cervical Cancer Screening in Brazil’ (Zeferino et al.)9, according to the changes observed in new international guidelines and knowledge updates. The most relevant and recent guidelines were assessed. Questions regarding the clinical practice were formulated, and the answers considered the perspective of the public and private sectors of the Brazilian health system. The review addressed risk-based strategies regarding age to start and stop screening, the use of cytology and colposcopy to support management decisions, treatment, follow-up strategies, and screening in specific groups, including vaccinated women. The update aims to improve the prevention of cervical cancer and to reduce overtreatment and the misuse of HPV testing.
Key-words accessibility of health servicesearly detection of cancerhuman papillomavirus DNA testsMass screeningUterine cervical neoplasmsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Carla Fabrine Carvalho
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Review Article
Commercial Surrogacy: An Overview
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(12):1141-1158
03-24-2022
Views310This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleCommercial Surrogacy: An Overview
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(12):1141-1158
03-24-2022Views310See moreAbstract
Objective
Surrogacy is the process in which a woman carries and delivers a baby to other person or couple, known as intended parents. When carriers are paid for surrogacy, this is known as commercial surrogacy. The objective of the present work is to review the legal, ethical, social, and cultural aspects of commercial surrogacy, as well as the current panorama worldwide.
Methods
This is a review of the literature published in the 21st century on commercial surrogacy.
Results
A total of 248 articles were included as the core of the present review. The demand for surrogate treatments by women without uterus or with important uterine disorders, single men and same-sex male couples is constantly increasing worldwide. This reproductive treatment has important ethical dilemmas. In addition, legislation defers widely worldwide and is in constant change. Therefore, patients look more and more for treatments abroad, which can lead to important legal problems between countries with different laws. Commercial surrogacy is practiced in several countries, in most of which there is no specific legislation. Some countries have taken restrictive measures against this technique because of reports of exploitation of carriers.
Conclusion
Commercial surrogacy is a common practice, despite important ethical and legal dilemmas. As a consequence of diverse national legislations, patients frequently resort to international commercial surrogacy programs. As of today, there is no standard international legal context, and this practice remains largely unregulated.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article
The Female Athlete Triad/Relative Energy Deficiency in Sports (RED-S)
- Alexandra Ruivo Coelho
,
- Gonçalo Cardoso
,
- Marta Espanhol Brito
,
- Inês Neves Gomes
,
- Maria João Cascais
07-30-2021
Views364PlumX Metrics- Citations
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleThe Female Athlete Triad/Relative Energy Deficiency in Sports (RED-S)
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):395-402
07-30-2021- Alexandra Ruivo Coelho
,
- Gonçalo Cardoso
,
- Marta Espanhol Brito
,
- Inês Neves Gomes
,
- Maria João Cascais
Views364See moreAbstract
In a healthy athlete, the caloric intake is sufficient for sports energy needs and body physiological functions, allowing a balance between energy availability, bone metabolism, andmenstrual cycle.Onthe other hand, an imbalance causedby low energy availability dueto a restrictive diet, eating disorders or long periods of energy expenditure leads to multisystemic deregulation favoring the essential functions of the body. This phenomenon, described as the female athlete triad, occurs in a considerable percentage of high-performance athletes, with harmful consequences for their future. The present review was carried out based on a critical analysis of themost recent publications available and aims to provide a global perception of the topic relative energy deficit in sport (RED-S). The objective is to promote theacquisition ofmore consolidated knowledgeon an undervaluedtheme, enabling the acquisition of preventive strategies, early diagnosis and/or appropriate treatment.
PlumX Metrics- Citations
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Alexandra Ruivo Coelho
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Original Article
Screening of Perinatal Depression Using the Edinburgh Postpartum Depression Scale
- Tenilson Amaral Oliveira
,
- Guilherme Guarany Cardoso Magalhães Luzetti
,
- Márcia Maria Auxiliadora Rosalém
,
- Corintio Mariani Neto
03-04-2022
Views367This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleScreening of Perinatal Depression Using the Edinburgh Postpartum Depression Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(5):452-457
03-04-2022- Tenilson Amaral Oliveira
,
- Guilherme Guarany Cardoso Magalhães Luzetti
,
- Márcia Maria Auxiliadora Rosalém
,
- Corintio Mariani Neto
Views367See moreAbstract
Objective
To detect depression during pregnancy and in the immediate postpartum period using the Edinburgh postpartum depression scale (EPDS).
Methods
Cross sectional study of 315 women, aged between 14 and 44 years, who received perinatal care at the Leonor Mendes de Barros Hospital, in São Paulo, between July 1st, 2019 and October 30th, 2020. The cutoff point suggesting depression was ≥ 12.
Results
The screening indicated 62 (19.7%) patients experiencing depression. Low family income, multiparity, fewer prenatal appointments, antecedents of emotional disorders, dissatisfaction with the pregnancy, poor relationship with the partner, and psychological aggression were all risk factors associated with depression in pregnancy or in the immediate postpartum period. Antecedents of depression and psychology aggression during pregnancy were significant variables for predicting perinatal depression in the multivariate analysis.
Conclusion
There is a significant association between the occurrence of perinatal depression and the aforementioned psychosocial factors. Screening patients with the EPDS during perinatal and postpartum care could facilitate establishing a line of care to improve the wellbeing of mother and infant.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Tenilson Amaral Oliveira
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Original Article
Prevalence of Premenstrual Syndrome and Associated Factors Among Academics of a University in Midwest Brazil
- Ana Paula Rodrigues Rezende
,
- Fernanda Rassi Alvarenga
,
- Marcelo Ramos
,
- Débora Luiza Franken
,
- Juvenal Soares Dias da Costa
,
[ … ], - Vera Maria Vieira Paniz
04-08-2022
Views283This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticlePrevalence of Premenstrual Syndrome and Associated Factors Among Academics of a University in Midwest Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(2):133-141
04-08-2022- Ana Paula Rodrigues Rezende
,
- Fernanda Rassi Alvarenga
,
- Marcelo Ramos
,
- Débora Luiza Franken
,
- Juvenal Soares Dias da Costa
,
- Marcos Pascoal Pattussi
,
- Vera Maria Vieira Paniz
Views283Abstract
Objective
To investigate the prevalence of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) in university students, the factors associated with PMS, the most prevalent symptoms, and the interference of symptoms in academic, family, social, and work activities.
Methods
This cross-sectional study included 1,115 university students aged ≥ 18 years from the University of Rio Verde, Goiás. Premenstrual syndrome and PMDD were identified using the Premenstrual Symptoms Screening Tool. Associations with sociodemographic, behavioral, reproductive, nutritional, and health factors were investigated using the Poisson regression.
Results
The prevalence of PMS was 46.9% (95% confidence interval [CI] 44.0-49.8), and of PMDD, 11.1% (95% CI 9.3-13.0). The most prevalent symptoms were physical, such as breast tenderness, bloating, e weight gain (73%); followed by psychological ones such as overeating/food cravings, tearful/more sensitive to rejection (> 60%). More than 30% of the patients reported that the symptoms interfered in a moderate-tosevere way in their social and academic activities. After adjusted analysis, PMS was more prevalent in those who were attending the 1st/2nd semester of college (prevalence ratio [PR] 1.44; 95% CI 1.14-1.80), those who consumed alcohol in the last 30 days (PR 1.23; 95% CI 1.04-1.47), and those who had depression (PR 1.49; 95% CI 1.30-1.71).
Conclusion
Almost half of the university students had PMS and ~ 11%, PMDD. Physical symptoms were themost common and interfered in amoderate-to-severe way in various aspects of life. Attending the first semesters, consuming alcohol, and having depression were risk factors for PMS. The identification of risk factors for PMS is essential to prevent symptoms and reduce the impact of the syndrome.
Key-words Cross-sectional studiespremenstrual dysphoric disorderPremenstrual syndromeRisk factorsStudentsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Ana Paula Rodrigues Rezende
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Review Article
Cognitive Behavioral Therapy in Endometriosis, Psychological Based Intervention: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):295-303
06-27-2022
Views288This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleCognitive Behavioral Therapy in Endometriosis, Psychological Based Intervention: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):295-303
06-27-2022Views288Abstract
Introduction
Endometriosis is an inflammatory disease that affects women of reproductive age, causing pain and the possibility of infertility. Endometriosis was associated to low life quality and research shows the impact of endometriosis in several areas of life, justifying how these patients are more likely to develop depression, anxiety, and stress.
Objective
The aim of the present systematic review was to explore the field of psychology in endometriosis, identifying studies that used the cognitive behavioral therapy technique as a treatment for endometriosis and chronic pelvic pain.
Methods
The keywords used were Endometriosis and Behavioral Therapy; Behavioral Disciplines and Activities; Cognitive Behavioral Therapy; Mental Health; Psychological Techniques; Psychology; Psychotherapy; Mental Health Services; and the search was performed in the following databases: PubMed/Medline, Scielo, Lilacs, and Capes. The study followed the PRISMA guidelines and all studies whose intervention strategy used was related to cognitive-behavioral therapy were considered.
Results
Of the 129 articles found, only 5 were selected, and it was possible to identify that the psychological intervention whose approach brought cognitive-behavioral therapy techniques promoted a decrease in the sensation of pain, improvements in the scores of depression and stress, and significant changes in aspects of quality of life such as vitality, physical and social functioning, emotional well-being, control, and autonomy.
Conclusion
Cognitive-behavioral therapy can be very promising to take care of the emotional side of those who have endometriosis However, the present systematic review highlights the need to develop more structured studies with consistent, clear and replicablemethods to reach a psychological intervention protocol for patients who live with this gynecological-physical-emotional condition.
Key-words Chronic pelvic paincognitive behavioral therapyEndometriosispsychological interventionQuality of lifesystematic reviewsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article
Interventions among Pregnant Women in the Field of Music Therapy: A Systematic Review
- Bruna Mayumi Omori Shimada
,
- Magda da Silva Oliveira Menezes dos Santos
,
- Mayara Alvares Cabral
,
- Vanessa Oliveira Silva
,
- Gislaine Cristina Vagetti
07-30-2021
Views330PlumX Metrics- Citations
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleInterventions among Pregnant Women in the Field of Music Therapy: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):403-413
07-30-2021- Bruna Mayumi Omori Shimada
,
- Magda da Silva Oliveira Menezes dos Santos
,
- Mayara Alvares Cabral
,
- Vanessa Oliveira Silva
,
- Gislaine Cristina Vagetti
Views330See moreAbstract
Objective
To investigate in the literature the studies on the benefits ofmusic therapy interventions among pregnant women in the prenatal, delivery and postpartum periods.
Data Sources
The search for articles was carried out in the following electronic databases: VHL, LILACS, SciELO, Portal CAPES, PsycINFO, ERIC, PubMed/Medline, and journals specialized in this field: Revista Brasileira de Musicoterapia (“Brazilian Journal of Music Therapy”) and Voices.
Study Selection
Descriptors in Portuguese (musicoterapia, gravidez, gestantes, revisão), English (music therapy, pregnancy, pregnant women, review) and Spanish (musicoterapia, embarazo, mujeres embarazadas, revisión) were used. The search was delimited between January 2009 and June 2019. The process of selection and evaluation of the articles was performed through peer review.
Data Collectio
n The following data were extracted: article title, year of publication, journal, author(s), database, country and date of collection, purpose of the study, sample size, type of care, intervention, instruments used, results, and conclusion. The data were organized in chronological order based on the year of publication of thestudy.
Summary of the Data
In total, 146 articles were identified, and only 23 studies were included in this systematic review. The articles found indicate among their results relaxation, decreased levels of anxiety, psychosocial stress and depression, decreased pain, increase in the maternal bond, improvement in the quality of sleep, control of the fetal heart rate and maternal blood pressure, and decreased intake of drugs in the postoperative period.
Conclusion
Music therapy during the prenatal, delivery and postpartum periods can provide benefits to pregnant women and newborns, thus justifying its importance in this field.
PlumX Metrics- Citations
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Bruna Mayumi Omori Shimada
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Review Article
The Correlation between Chlamydia Trachomatis and Female Infertility: A Systematic Review
- Laura Gazal Passos
,
- Paula Terraciano
,
- Nicole Wolf
,
- Fernanda dos Santos de Oliveira
,
- Isabel de Almeida
,
[ … ], - Eduardo Pandolfi Passos
08-15-2022
Views331This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleThe Correlation between Chlamydia Trachomatis and Female Infertility: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(6):614-620
08-15-2022- Laura Gazal Passos
,
- Paula Terraciano
,
- Nicole Wolf
,
- Fernanda dos Santos de Oliveira
,
- Isabel de Almeida
,
- Eduardo Pandolfi Passos
Views331Abstract
The impact of Chlamydia trachomatis (CT) infection on female’s fertility is not completely established yet, since the level of evidence associating these factors is still weak. Hence, the goal of the present review is to contribute to a better elucidation of this matter. The electronic database chosen was the Medline/PubMed, with the last survey on May 11, 2021. Publication date was used as a filter, with the previous 5 years having been selected. The following describers were used: chlamydia trachomatis AND infertility; chlamydia trachomatis AND tubal alteration AND infertility; chlamydia AND low pregnancy rates. From the 322 studies screened, 293 that failed to meet our eligibility criteria were excluded. Subsequently, we removed seven studies for not having the possible correlation between CT infections and female infertility as its main focus, and three for being about sexually transmitted infections (STIs) in general. Moreover, two studies designed as reviews were also excluded. Ergo, we included 17 studies in our qualitative analysis. The authors conducted research individually and analyzed carefully the studies selected. As we retrieved the information needed for our study through reading the texts, no contact was made with the authors of the studies selected. This systematic review corroborates the hypothesis that CT infection potentiates female infertility, as 76.47% of the included studies found a positive correlation between them. We conclude that there is an important association between CT infection and female infertility. Ergo, making CT screening part of the infertility investigation routine is relevant and has a reasonable justification.
Key-words Chlamydia trachomatishuman reproductionInfertilitySexually transmitted diseasestubal factor infertilitySee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Laura Gazal Passos
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Review Article
Polycystic Ovary Syndrome in Adolescence: Challenges in Diagnosis and Management
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(4):425-433
06-27-2022
Views301This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticlePolycystic Ovary Syndrome in Adolescence: Challenges in Diagnosis and Management
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(4):425-433
06-27-2022Views301See moreAbstract
Diagnosing polycystic ovary syndrome (PCOS) during adolescence is challenging since normal pubertal development overlap typical features of this syndrome. The authors aim to summarize the existing evidence concerning PCOS in adolescence, particularly its diagnostic criteria and therapeutic options. A search throughout medical databases such as PubMed and MedScape was performed. Diagnostic criteria include irregular menstrual cycles according to time postmenarche and evidence of clinical hyperandrogenism and/or biochemical hyperandrogenism, provided other causes have been excluded. Polycystic ovarianmorphology ought not to be used as a diagnostic criterion. Treatment should targetmanifestations and/or comorbidities, even in the absence of a definite diagnosis. Lifestyle interventions are the first-line treatment. Combined oral contraceptives, metformin or antiandrogens may also be considered as adjuvants. Screening for PCOS in adolescence is crucial as it allows an early intervention on the symptoms and comorbidities presented leading to better long-term reproductive and metabolic outcomes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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