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Resumos de Teses07-01-2001
Avaliação Prospectiva dos Índices de Resistência e Pulsatilidade nas Artérias Renais de Gestantes Normais
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):676-677
Abstract
Resumos de TesesAvaliação Prospectiva dos Índices de Resistência e Pulsatilidade nas Artérias Renais de Gestantes Normais
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):676-677
DOI 10.1590/S0100-72032001001000015
Views47Avaliação Prospectiva dos Índices de Resistência e Pulsatilidade nas Artérias Renais de Gestantes Normais […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses07-01-2001
Acurácia dos Métodos Clínico e Ecográfico no Diagnóstico de Adenomiose
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):676-676
Abstract
Resumos de TesesAcurácia dos Métodos Clínico e Ecográfico no Diagnóstico de Adenomiose
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):676-676
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses07-01-2001
Cirurgia de Alta Freqüência em Lesões Intra-epiteliais de Alto Grau do Colo Uterino
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):675-675
Abstract
Resumos de TesesCirurgia de Alta Freqüência em Lesões Intra-epiteliais de Alto Grau do Colo Uterino
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):675-675
DOI 10.1590/S0100-72032001001000013
Views44Cirurgia de Alta Freqüência em Lesões Intra-epiteliais de Alto Grau do Colo Uterino […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses07-01-2001
Curva de Normalidade da Área de Secção Transversa do Cordão Umbilical Aferida pela Ultra-Sonografia e sua Correlação com Parâmetros Antropométricos em Gestações Normais
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):675-675
Abstract
Resumos de TesesCurva de Normalidade da Área de Secção Transversa do Cordão Umbilical Aferida pela Ultra-Sonografia e sua Correlação com Parâmetros Antropométricos em Gestações Normais
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):675-675
DOI 10.1590/S0100-72032001001000012
Views69Curva de Normalidade da Área de Secção Transversa do Cordão Umbilical Aferida pela Ultra-Sonografia e sua Correlação com Parâmetros Antropométricos em Gestações Normais […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses07-01-2001
Diferencial dos Tumores Sólidos Palpáveis da Mama
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):674-674
Abstract
Resumos de TesesDiferencial dos Tumores Sólidos Palpáveis da Mama
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):674-674
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Resumos de Teses07-01-2001
Aspectos Clínicos e Epidemiológicos das Mulheres Climatéricas de um Programa de Saúde da Família em Cuiabá: MT, 1999.
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):674-674
Abstract
Resumos de TesesAspectos Clínicos e Epidemiológicos das Mulheres Climatéricas de um Programa de Saúde da Família em Cuiabá: MT, 1999.
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):674-674
DOI 10.1590/S0100-72032001001000010
Views46Aspectos Clínicos e Epidemiológicos das Mulheres Climatéricas de um Programa de Saúde da Família em Cuiabá ¾ MT, 1999. […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article07-01-2001
Effect of Betamethasone on Pregnant Rats: Impact on Corticosterone Level and Maternal and Fetal Adrenal Glands
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):667-673
Views116This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleEffect of Betamethasone on Pregnant Rats: Impact on Corticosterone Level and Maternal and Fetal Adrenal Glands
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):667-673
DOI 10.1590/S0100-72032001001000009
Views116See morePurpose: the repetitive use of antenatal corticosteroid therapy for acceleration of fetal lung maturation has been common in cases at risk of preterm delivery. We studied the corticosterone levels at term and the morphologic aspects in the maternal and fetal adrenal glands submitted to the effect of betamethasone in the second half of rat pregnancy in order to verify its consequences. Methods: thirty female pregnant rats were divided into three groups of ten animals each. Group I received betamethasone on the 11th, 12th, 18th and 19th day of pregnancy. Group II received distilled water on the same days (control group). Group III did not receive any drug (stress control group). All rats were sacrificed on the 20th day of pregnancy when plasma corticosterone levels of dams were assessed and the maternal and fetal adrenal glands were studied by light microscopy. Results: plasma corticosterone level of dams was lower in the group treated with betamethasone (4.8 mg/dL) when compared with the control groups (17.7 and 26.8 mg/dL). The light microscopy study revealed cytoplasmatic vacuolation in the fasciculate zone in the maternal and fetal adrenal glands, which indicates adrenal suppression. Conclusions: the antenatal repetitive and prolonged use of corticosteroids in pregnant rats for acceleration of lung fetal maturation causes maternal and fetal adrenal suppression.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article07-01-2001
Brain-sparing Effect Detected by Color Doppler: Perinatal Outcome
- Cleide Mara Mazzotti Oliveira Franzin,
- João Luiz Pinto e Silva,
- Emílio Francisco Marussi,
- Silvana Varella Parmigiani
Views78This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleBrain-sparing Effect Detected by Color Doppler: Perinatal Outcome
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(10):659-665
DOI 10.1590/S0100-72032001001000008
- Cleide Mara Mazzotti Oliveira Franzin,
- João Luiz Pinto e Silva,
- Emílio Francisco Marussi,
- Silvana Varella Parmigiani
Views78See morePurpose: evaluation of perinatal outcome of brain-sparing effect detected by color Doppler. Methods: brain-sparing effect was detected in 32 fetuses at the Ultrasound Service of the Center for Integral Attention to Women’s Health at Campinas State University (UNICAMP). The diagnosis of brain-sparing effect was made when the ratio between middle cerebral artery and umbilical artery pulsatility indexes was below one (IPACM/IPAU <1). The measurement was obtained with color Doppler equipment Toshiba SSH-140A. Results: admission to neonatal intensive care unit (ICU) was necessary in 26 fetuses (89.6%). The number of days in ICU varied from 1 to 83 days, with a mean of 22 days. Fetal mortality rate was 3 in 32 (9.4%) and perinatal mortality was 9 in 29 (31%). Considering the gestational age by the Capurro method, the incidence of birth below 36 weeks was 21 in 32 (65.6%). Intrauterine growth restriction occurred in 71.8% of the cases and hypoglycemia in 44.8%. Conclusions: brain-sparing effect is a condition in which the fetus is at serious risk of adverse perinatal outcome and Doppler studies might be helpful in the obstetric management.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Review Article09-18-2024
Neonatal and maternal outcomes of mRNA versus Non-mRNA COVID-19 vaccines in pregnant patients: a systematic review and meta-analysis
- Juliana Almeida Oliveira
,
- Eloisa Gonçalves da Silva
,
- Ayse Filiz Gokmen Karasu
,
- Anelise Maria Nicolau Silva
,
- Chris Elizabeth Philip
Abstract
Review ArticleNeonatal and maternal outcomes of mRNA versus Non-mRNA COVID-19 vaccines in pregnant patients: a systematic review and meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo69
- Juliana Almeida Oliveira
,
- Eloisa Gonçalves da Silva
,
- Ayse Filiz Gokmen Karasu
,
- Anelise Maria Nicolau Silva
,
- Chris Elizabeth Philip
Views252Abstract
Objective
To compare the effectiveness and safety of non-mRNA versus mRNA COVID-19 vaccines on pregnant women and their newborns in a systematic review with meta-analysis.
Data sources
We searched PubMed, Embase, and Cochrane Central in May 2023.
Study selection
The search strategy yielded 4451 results, 16 studies were fully reviewed. We selected case-control studies analysing non-mRNA versus mRNA vaccines. Data collection and analysis: we assessed the risk of bias using the Cochrane Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I) tool. Standardised mean differences were pooled using random-effect models.
Data synthesis
We identified 8 prospective and retrospective studies with a total of 32,153 patients. Non-mRNA vaccines were associated with a higher incidence of fever (OR 2.67; 95% CI 2.08-3.43; p<0.001), and a lower incidence of fetal or neonatal death (OR 0.16; 95% CI 0.08-0.33; p<0.001). In subgroup analyses, the Jansen vaccine (Ad26.COV2.S) was found to have a higher rate of premature labor/delivery (OR 4.48; 95% CI 1.45-13.83; p=0.009) and missed/spontaneous abortion (OR 1.90; 95% CI 1.09-3.30; p=0.02), as compared with the Pfizer (BNT162b2) vaccine.
Conclusion
non-mRNA vaccines are associated with a lower incidence of fetal or neonatal death among pregnant women who receive a Covid19 vaccine, although at an increased rate of pyrexia compared with mRNA vaccines. Other studies are required for better assessment.
PROSPERO
CRD42023421814
Key-words coronavirus infectionsCOVID-19COVID-19 vaccinesInfant, newbornmRNA vaccinesPregnancy complicationsPregnant womenSARS-CoV-2See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Juliana Almeida Oliveira
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Original Article09-18-2024
Multidisciplinary team training in postpartum hemorrhage: impact on the use of blood products
- Carina Bauer Luiz
,
- Ana Lúcia Letti Müller
,
- Cristiano Caetano Salazar
,
- Teresinha Zanella
,
- Gabriel Cardozo Müller
,
[ … ], - Janete Vettorazzi
Abstract
Original ArticleMultidisciplinary team training in postpartum hemorrhage: impact on the use of blood products
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo67
- Carina Bauer Luiz
,
- Ana Lúcia Letti Müller
,
- Cristiano Caetano Salazar
,
- Teresinha Zanella
,
- Gabriel Cardozo Müller
,
- Amanda Vilaverde Perez
,
- Mariana Sbaraini
,
- Maria Lucia Oppermann
,
- Janete Vettorazzi
Views268See moreAbstract
Objective
Compare the number of puerperal women submitted to blood transfusion before and after the implementation of a care protocol for postpartum hemorrhage (PPH) with multidisciplinary team training.
Methods
Cross-sectional study in a university hospital, analyzing births from 2015 to 2019, compared the use of blood products before and after the adoption of a PPH protocol with multidisciplinary training.
Results
Between 2015 and 2019, there were 17,731 births, with 299 (1.7%) postpartum women receiving blood products and 278 postpartum women were considered for this analysis, 128 (0.7%) at Time 1 and 150 (0.8%) at Time 2. After the multiprofessional team training (T2), there was a difference in the complete use of the PPH protocol (use of oxytocin, misoprostol and tranexamic acid) (T1 = 5.1% x T2 = 49.5%, p≤0.0001). An individual categorized analysis revealed that, in the T2 period, there was lower use of blood component units per patient compared to T1 (Mann-Whitney, p=0.006). It should be noted that at T1 and T2, 54% and 24% respectively received two units of blood products. It is important to highlight that after the multidisciplinary team training for the PPH protocol, the goal of zero maternal death due to hemorrhage was reached.
Conclusion
The adoption of a specific protocol for PPH, combined with the training of a multidisciplinary team, had an impact on the ability to identify women at high risk of hemorrhage, resulting in a decrease in the use of blood components.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Carina Bauer Luiz
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Original Article09-06-2024
Immediate prepectoral versus submuscular breast reconstruction in nipple-sparing mastectomy: a retrospective cohort analysis
- Francisco Pimentel Cavalcante
,
- Ticiane Oliveira Lima
,
- Ryane Alcantara
,
- Amanda Cardoso
,
- Guilherme Novita
,
[ … ], - Eduardo Millen
Views261This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleImmediate prepectoral versus submuscular breast reconstruction in nipple-sparing mastectomy: a retrospective cohort analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo76
- Francisco Pimentel Cavalcante
,
- Ticiane Oliveira Lima
,
- Ryane Alcantara
,
- Amanda Cardoso
,
- Guilherme Novita
,
- Felipe Zerwes
,
- Eduardo Millen
Views261Abstract
Objective
To evaluate early complications in prepectoral breast reconstruction.
Methods
A retrospective cohort study including 180 consecutive cases of nipple-sparing mastectomy, comparing immediate breast reconstruction with subpectoral to prepectoral mammary implants in 2012-2022. Clinical and demographic characteristics and complications in the first three months following surgery were compared between the two techniques.
Results
The prepectoral technique was used in 22 cases (12.2%) and the subpectoral in 158 (87.8%). Median age was higher in the prepectoral group (47 versus 43.8 years; p=0.038), as was body mass index (25.1 versus 23.8; p=0.002) and implant volume (447.5 versus 409 cc; p=0.001). The prepectoral technique was more associated with an inframammary fold (IMF) incision (19 cases, 86.4% versus 85, 53.8%) than with periareolar incisions (3 cases, 13.6% versus 73, 46.2%); (p=0.004). All cases in the prepectoral group underwent direct-to-implant reconstruction compared to 54 cases (34.2%) in the subpectoral group. Thirty-eight complications were recorded: 36 (22.8%) in the subpectoral group and 2 (9.1%) in the prepectoral group (p=0.24). Necrosis of the nipple-areola complex/skin flap occurred in 27 patients (17.1%) in the subpectoral group (prepectoral group: no cases; p=0.04). The groups were comparable regarding dehiscence, seroma, infection, and hematoma. Reconstruction failed in one case per group (p=0.230). In the multivariate analysis, IMF incision was associated with the prepectoral group (aOR: 34.72; 95%CI: 2.84-424.63).
Conclusion
The incidence of early complications was comparable between the two techniques and compatible with previous reports. The clinical and demographic characteristics differed between the techniques. Randomized clinical trials are required.
Key-words Breast implantationBreast implantsBreast neoplasmsMammaplastyMastectomyNipplesPectoralis musclesSurgical procedures, operativeSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Francisco Pimentel Cavalcante
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Editorial09-06-2024
The importance of the quadrivalent HPV vaccine in the elimination of cervical cancer in Brazil
- Cecília Martins Roteli-Martins
,
- Ana Goretti Kalume Maranhão
,
- Susana Cristina Aidé Viviani Fialho
,
- Agnaldo Lopes da Silva-Filho
Abstract
EditorialThe importance of the quadrivalent HPV vaccine in the elimination of cervical cancer in Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgoedt4
- Cecília Martins Roteli-Martins
,
- Ana Goretti Kalume Maranhão
,
- Susana Cristina Aidé Viviani Fialho
,
- Agnaldo Lopes da Silva-Filho
Views202HPV vaccination program in BrazilThe introduction of the quadrivalent HPV vaccine Gardasil 4V into the Brazilian National Immunization Schedule was approved by the National Committee for Technology Incorporation into the Unified Health System (Conitec) and incorporated into the National Immunization Schedule in 2014. This decision was based on a previous cost-effectiveness study that analyzed different […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Cecília Martins Roteli-Martins
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Original Article09-06-2024
Thinking on the purposes, roles and activities of networks for research on maternal and perinatal health: opinions of coordinators and members
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo75
Abstract
Original ArticleThinking on the purposes, roles and activities of networks for research on maternal and perinatal health: opinions of coordinators and members
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo75
Views124See moreAbstract
Objective
To identify the opinion of coordinators and members about the essential characteristics and to understand the research networks characteristics, to facilitate their implementation, sustainability and effectiveness so it can be replicated in low and middle-income countries.
Methods
A qualitative study using a semi-structured interview technique was conducted. We selected potential members, managers and participants of networks from publications identified in PubMed. After checking the FIGO congress program, we identified authors who were assigned as speakers at the event. An invitation was sent and interviews were scheduled.
Results
In total, eleven interviews were performed. Coordinators and members of networks have the same goal when they decide to participate in a network. In general, they cited that these individuals had to be committed, responsible and enthusiastic people. The network should be composed also of postgraduate students. A network should allow multi-leadership, co-responsibility, autonomy and empowerment of its members. Effective communication was mentioned as an important pillar for network maintenance. Another motivation is being an author or coauthor in publications. One way to maintain a network running is social or governmental commitment, after resources expire, studies continue.
Conclusion
Networks are different due to the social context where they are inserted, however, some characteristics are common to all of them, such as having engaged leaders. For an effective and sustainable network, commitment and motivation in a leader and members are more in need than financial resources. Ideally, to ensure the operation of the network, the institution where the leader is linked should support this network.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article09-06-2024
Morbidity associated with emergency surgery versus scheduled surgery in patients with placenta accreta spectrum
- Juan José Saldarriaga-Hoyos
,
- Daniela Sarria-Ortiz
,
- Valentina Galindo-Velasco
,
- Luisa Fernanda Rivera-Torres
,
- Albaro José Nieto-Calvache
Abstract
Original ArticleMorbidity associated with emergency surgery versus scheduled surgery in patients with placenta accreta spectrum
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo74
- Juan José Saldarriaga-Hoyos
,
- Daniela Sarria-Ortiz
,
- Valentina Galindo-Velasco
,
- Luisa Fernanda Rivera-Torres
,
- Albaro José Nieto-Calvache
Views148See moreAbstract
Objective
This study aims to evaluate the clinical outcomes of surgical management for placenta accreta spectrum in a Latin American reference hospital specializing in this condition. The evaluation involves a comparison between surgeries performed on an emergent and scheduled basis.
Methods
A retrospective cohort study was conducted on patients with placenta accreta spectrum who underwent surgery between January 2011 and November 2021 at a hospital in Colombia, using data from the institutional PAS registry. The study included patients with intraoperative and/or histological confirmation of PAS, regardless of prenatal suspicion. Clinical outcomes were compared between patients who had emergent surgeries and those who had scheduled surgeries. Descriptive analysis involved summary measures and the Shapiro-Wilk test for quantitative variables, with comparisons made using Pearson’s Chi-squared test and the Wilcoxon rank sum test, applying a significance level of 5%.
Results
A total of 113 patients were included, 84 (74.3%) of them underwent scheduled surgery, and 29 (25.6%) underwent emergency surgery. The emergency surgery group required more transfusions (72.4% vs 48.8%, p=0.047). Patients with intraoperative diagnosis of placenta accreta spectrum (21 women, 19.5%) had a greater volume of blood loss than patients taken into surgery with known presence of placenta accreta spectrum (3500 ml, IQR 1700 – 4000 vs 1700 ml, IQR 1195-2135. p <0.001).
Conclusion
Patients with placenta accreta spectrum undergoing emergency surgery require transfusions more frequently than those undergoing scheduled surgery
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Juan José Saldarriaga-Hoyos
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Review Article09-06-2024
Biochemical markers for prediction of the first half pregnancy losses: a review
- Meruyet Kuspanova
,
- Andrey Gaiday
,
- Nurzhamal Dzhardemaliyeva
,
- Maxat Tuganbayev
,
- Maksym Gorobeiko
,
[ … ], - Akylbek Tussupkaliyev
Views222This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleBiochemical markers for prediction of the first half pregnancy losses: a review
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo72
- Meruyet Kuspanova
,
- Andrey Gaiday
,
- Nurzhamal Dzhardemaliyeva
,
- Maxat Tuganbayev
,
- Maksym Gorobeiko
,
- Andrii Dinets
,
- Saule Bermagambetova
,
- Zhanna Amirbekova
,
- Gulshat Oraltayeva
,
- Dinara Omertayeva
,
- Akylbek Tussupkaliyev
Views222Abstract
Objective
26% of all pregnancies end in miscarriage, and up to 10% of clinically diagnosed pregnancies, and recurrent pregnancy loss is 5% among couples of childbearing ages. Although there are several known causes of pregnancy loss in the first half, including recurrent pregnancy loss, including parental chromosomal abnormalities, uterine malformations, endocrinological disorders, and immunological abnormalities, about half of the cases of pregnancy loss in its first half remain unexplained.
Methods
The review includes observational controlled studies (case-control or cohort, longitudinal studies, reviews, meta-analyses), which include the study of biochemical factors for predicting pregnancy losses in the first half, in singlet pregnancy. The Newcastle-Ottawa Scale (NOS) was used to assess the research quality.
Results
Finally, 27 studies were included in the review, which has 134904 examined patients. The results of the review include estimates of β-human chorionic gonadotropin, progesterone, pregnancy-associated protein – A, angiogenic vascular factors, estradiol, α-fetoprotein, homocysteine and CA-125 as a predictors or markers of the first half pregnancy losses.
Conclusion
It may be concluded that to date, research data indicate the unavailability of any reliable biochemical marker for predicting pregnancy losses in its first half and require either a combination of them or comparison with clinical evidence. A fairly new model shall be considered for the assessment of α-fetoprotein in vaginal blood, which may have great prospects in predicting spontaneous miscarriages.
Key-words Biochemical markerLaboratory markerMiscarriagemissed abortionpredictionPregnancySpontaneous abortionSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Meruyet Kuspanova
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Original Article09-06-2024
Association between dietary patterns and infant birth weight in brazilian pregnancy women with gestational diabetes: a cross-sectional study
- Luciana da Cunha Bernardes Argenta
,
- Nadya Helena Alves dos Santos
,
- Cláudia Saunders
,
- Joana Dias da Costa
,
- Letícia Victoria Souza da Cunha
,
[ … ], - Patricia de Carvalho Padilha
Views183This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleAssociation between dietary patterns and infant birth weight in brazilian pregnancy women with gestational diabetes: a cross-sectional study
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo68
- Luciana da Cunha Bernardes Argenta
,
- Nadya Helena Alves dos Santos
,
- Cláudia Saunders
,
- Joana Dias da Costa
,
- Letícia Victoria Souza da Cunha
,
- Pamela Melo Krok Fedeszen
,
- Patricia de Carvalho Padilha
Views183See moreAbstract
Objective
To evaluate the association between the dietary patterns (DPs) of pregnant women with GDM (gestational diabetes mellitus) and the birth weight (BW) of the infants.
Methods
Cross-sectional study with 187 adult pregnant women with GDM attended at a maternity in Rio de Janeiro from 2011 to 2014. Dietary intake was assessed in the third trimester using a semiquantitative food frequency questionnaire (FFQ). The outcomes were BW and weight adequacy for gestational age (GA). Reduced Rank Regression (RRR) was used to explain the following response variables: density of carbohydrates, fibres, and saturated fatty acids. Statistical analyzes included multinomial logistic regression models.
Results
The mean BW was 3261.9 (± 424.5) g. Three DPs were identified, with DP 3 (high consumption of refined carbohydrates, fast foods/snacks, whole milk, sugars/sweets, and soft drinks and low consumption of beans, vegetables, and low-fat milk and derivatives) being the main pattern, explaining 48.37% of the response variables. In the multinomial logistic regression analysis no statistically significant association was found between the tertiles of DPs and BW or the adequacy of weight for GA, even after adjustments of confounding covariates.
Conclusion
No significant associations were found between maternal DPs in the third trimester of pregnancy and infant BW or adequacy of weight for GA.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Luciana da Cunha Bernardes Argenta
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Review Article03-18-2025
Short cervix and use of cervical pessary for preventing preterm birth in singleton and twin pregnancies: a systematic review and meta-analysis
- Ana Clara Felix de Farias Santos
,
- Nicole dos Santos Pimenta
,
- Ana Gabriela Alves Pereira
,
- Gabriela Oliveira Gonçalves Molino
,
- Maírla Marina Ferreira Dias
,
[ … ], - Pedro Henrique Costa Matos da Silva
Abstract
Review ArticleShort cervix and use of cervical pessary for preventing preterm birth in singleton and twin pregnancies: a systematic review and meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo10
- Ana Clara Felix de Farias Santos
,
- Nicole dos Santos Pimenta
,
- Ana Gabriela Alves Pereira
,
- Gabriela Oliveira Gonçalves Molino
,
- Maírla Marina Ferreira Dias
,
- Pedro Henrique Costa Matos da Silva
Views173See moreAbstract
Objective:
Preterm birth remains a significant contributor to neonatal morbidity and mortality. The use of cervical pessaries as an intervention for preventing preterm delivery in women with a short cervix has been a subject of interest. We evaluated the effectiveness of cervical pessary compared to standard care in preventing preterm delivery in women with a short cervix.
Data source:
Databases were systematically searched in PubMed, Cochrane, and Embase databases in December 2023.
Study selection:
Randomized clinical trials with the outcomes of interest were included.
Data collect:
We computed risk ratios for binary endpoints, with 95% confidence intervals. Heterogeneity was assessed using I2 statistics. Data were analyzed using R software (version 4.3.0). The primary outcomes of interest were preterm delivery before 37 weeks, and preterm delivery before 34 weeks.
Data synthesis:
Seventeen studies with 5,704 patients were included. The use of cervical pessary was associated with a decreased risk of preterm delivery before 37 (RR 0.88; 95% CI 0.81-0.96) and 34 weeks (RR 0.79; 95% CI 0.63-0.99) of gestation in twin pregnancies as compared to standard care without progesterone. There were no significant differences in preterm delivery in singleton pregnancy, neonatal outcomes, preterm premature rupture of the membranes or chorioamnionitis.
Conclusion:
The use of cervical pessary was associated with a significant reduction in preterm delivery at 34 and 37 weeks of gestation in twin pregnancies among patients with a short cervix compared to no treatment. No significant difference was found in singleton pregnancies or maternal outcomes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Ana Clara Felix de Farias Santos
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Short Communication03-18-2025
Contraception in adolescents with mental disorders: adherence and satisfaction in the use of depot medroxyprogesterone acetate
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo9
Abstract
Short CommunicationContraception in adolescents with mental disorders: adherence and satisfaction in the use of depot medroxyprogesterone acetate
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo9
Views172See moreAbstract
Objective:
To evaluate the continuation rate, satisfaction, and reasons for discontinuation of depot medroxyprogesterone acetate (DMPA) in adolescents treated in a mental health service.
Methods:
Prospective cohort study conducted in a reference unit for the care of adolescents with mental disorders (MDs) and intellectual disabilities (IDs). All patients received a gynecological consultation and an educational group on contraceptive methods. Sociodemographic data on age, education and gynecological data (menarche, coitarche, regularity of menstrual cycles and presence of symptoms) were collected. Follow-up was quarterly for 12 months, during which symptoms, desire to continue, and satisfaction with the use of the quarterly injectable were assessed.
Results:
Eight hundred and sixty-two sexually active adolescents were supported, 532 adolescents chose to use the quarterly injectable, and 69 of these agreed to participate in the study. The mean age of users was 15.5 years (SD=0.91). After 12 months of follow-up, 34 (49.3%) of the 69 adolescents continued to use the method and 36 (52.3%) were satisfied. Among the 33 (47.8%) who discontinued use, the most common reasons were irregular bleeding and weight gain.
Conclusions:
Adolescents with intellectual disabilities and/or other mental disorders showed a significant rate of continuation and satisfaction with the use of the depot medroxyprogesterone acetate at 12 months, and the most common reasons for discontinuation were irregular uterine bleeding and weight gain.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article03-18-2025
The experience of pregnancy in the COVID-19 pandemic
- Mariana Corniani Lopes
,
- Cheryl Tatano Beck
,
- Zelina Hilária de Souza Rosa
,
- Erika de Sá Vieira Abuchaim
Abstract
Original ArticleThe experience of pregnancy in the COVID-19 pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo8
- Mariana Corniani Lopes
,
- Cheryl Tatano Beck
,
- Zelina Hilária de Souza Rosa
,
- Erika de Sá Vieira Abuchaim
Views189See moreAbstract
Objective:
To describe women’s experience of pregnancy during the COVID-19 pandemic.
Methods:
A qualitative study conducted in a private maternity hospital, from May, 2020 to November, 2021, with women aged ≥ 18 years, gestational age ≥ 36 weeks at birth and ≥ 24 hours post-partum. Data collected through semi-structured interviews, recorded, transcribed, and analyzed adopting Krippendorff’s Content Analysis as theoretical-methodological framework.
Results:
Four main themes emerged: Fear, Taking care and celebrating pregnancy: adjusting to the new reality, Harms of Isolation, and Benefits of Isolation. The fear of contamination and its impact on the health of mother and child resulted in the adoption of severe social isolation, including from those considered sources of support by the expecting mother. Overwhelmed, some of the participants reported loneliness and psychic suffering. The opportunity to focus on the pregnancy, the preparations for the arrival of the child, and the family made isolation a beneficial and positive period for other women.
Conclusion:
The experience of pregnancy in the Pandemic was an event outside of the ordinary and common. The expecting mother faced her worst fears on a daily basis and attended prenatal care, in order to ensure her child would be born healthy. The celebration of the baby’s life, amid so many deaths, had to be adjusted to the virtual environment. It was a tense, solitary, and ambiguous period, which demanded a lot from the mental health of some participants, but to others, brought advantages that would not have been possible in different times.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Mariana Corniani Lopes
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Original Article03-18-2025
Effect of COVID-19 on Brazilian cesarean and prematurity rates: a cross-sectional study
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo6
Abstract
Original ArticleEffect of COVID-19 on Brazilian cesarean and prematurity rates: a cross-sectional study
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo6
Views167See moreAbstract
Objective:
To investigate the relationship between prematurity and cesarean section rate in Brazil during the beginning of COVID-19 pandemic.
Methods:
Utilizing the Robson Classification, this study analyzed data from the Brazilian Ministry of Health’s Live Births Panel, comparing CSR) and group 10 (preterm deliveries) between 2019 (pre-pandemic) and 2021 (pandemic) in each of Brazilian states and the overall country. The prematurity and CSR were compared using prevalence ratio and confidence interval, and p-value was obtained. The variation of prematurity and CSR were compared through the coefficient of determination (R2).
Results:
A total of 5,522,910 deliveries were evaluated during the period. The CSR increased from 56.34% to 57.05% (p<0.01), and the frequency of preterm deliveries rose from 8.99% to 9.13% (p<0.01). The CSR increased in 23 States and decreased in 4 States, while the prematurity rate increased in 16 States and decreased in 10 States. A positive relationship between the increase of CSR and prematurity was observed during COVID-19, with an R2 value of 0.3121, suggesting a moderate association between these two variables.
Conclusion:
Between 2019 (pre-COVID-19 pandemic) and 2021 (the first full year of the COVID-19 pandemic), there was an increase in prematurity and CSR in Brazil. These increases were observed in most Brazilian states and may be correlated. However, it is impossible to establish a cause-effect relationship given the design of this study.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article03-18-2025
Accurate evaluation of mode of delivery and labor progression with angle of progression: a prospective cross-sectional
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo5
Abstract
Original ArticleAccurate evaluation of mode of delivery and labor progression with angle of progression: a prospective cross-sectional
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo5
Views157See moreAbstract
Objective:
To determine the validity of the angle of progression (AoP) in predicting delivery mode among women in the second stage of labor.
Designs:
This prospective cohort study was conducted at the Obstetrics and Gynecology unit (OBGYN) of two hospitals in Vietnam. Transperineal ultrasound was performed for each woman to measure the progression angle in the second phase of labor.
Participants:
A total of 725 women with singleton pregnancies with cephalic presentation at term
Methods:
Transperineal ultrasound was used to measure the angle of progression in the second labor phase and to identify the delivery method.
Results:
The rate of vaginal birth in women with an AoP ≥ 120° on transperineal ultrasound was 70.2%. The optimal cutoff point of AOP ≥122° with sensitivity and specificity for vaginal birth were 87.8% and 80.7%, respectively the area under the ROC curve of 0.887 (p<0.0001). The study's sample size was restricted owing to deficiencies in resources and time.
Conclusion:
The likelihood of achieving spontaneous vaginal delivery can be predicted by the angle of progression measured with transperineal intrapartum ultrasonography during the second stage of labor in women.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article03-18-2025
Gastrin-releasing peptide receptor: a promising new biomarker to identify cervical precursor lesions and cancer
- Martina Lichtenfels
,
- Rafaella Almeida Lima Nunes
,
- Rossana Veronica Mendoza López
,
- Camila Alves da Silva
,
- Luiz Carlos Zeferino
,
[ … ], - Lara Termini
Views137This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleGastrin-releasing peptide receptor: a promising new biomarker to identify cervical precursor lesions and cancer
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo4
- Martina Lichtenfels
,
- Rafaella Almeida Lima Nunes
,
- Rossana Veronica Mendoza López
,
- Camila Alves da Silva
,
- Luiz Carlos Zeferino
,
- Vanesca de Souza Lino
,
- Adhemar Longatto-Filho
,
- Louise De Brot
,
- Silvia Helena Rabelo-Santos
,
- Daniela Baumann Cornelio
,
- Enrique Boccardo
,
- Caroline Brunetto de Farias
,
- Lara Termini
Views137Abstract
Objective:
This study aimed to verify the relation between gastrin-releasing peptide receptor (GRPR), oncogenic Human Papillomavirus (HPV) and cervical lesions severity.
Methods:
GRPR mRNA levels were evaluated in cervical cancer-derived cell lines and in primary keratinocytes expressing HPV16 oncogenes by RT-PCR. GRPR protein expression was assessed by immunohistochemistry in organotypic cell cultures derived from keratinocytes transduced with HPV16 oncogenes and in 208 cervical samples, including 59 non-neoplastic tissue, 28 cervical intraepithelial neoplasia grade 3 (CIN3), 44 squamous cell carcinomas (SCC) and 77 adenocarcinomas (ADC). Generic primers (GP5+/GP6+) were used to identify HPV infection in tissue samples. Experiments involving cell lines were analyzed through non-parametric tests (Kruskal Wallis), and Fisher’s Exact Test for human tissues samples. All statistical tests were considered significant at p <0.05. Immunohistochemical evaluation was conducted independently and blindly by two observers (AD- LO). Any discordant findings were resolved through discussion to reach a consensus score.
Results:
GRPR mRNA levels were not increased in cells expressing HPV16 or HPV18 oncogenes. However, at the protein level, GRPR was upregulated in organotypic cell cultures containing HPV oncogenes. Besides, it was identified an association between GRPR expression and cervical lesion severity (p < 0.0001). The detection rate of high-risk HPV DNA was directly correlated with cervical disease. Nonetheless, HPV infection was not directly associated with GRPR in cervical samples.
Conclusion:
GRPR expression is highly predictive of cervical lesion severity, irrespective of HPV infection and might contribute to improving patient’s therapeutic management as well as being used a marker of disease progression.
Key-words AdenocarcinomaCarcinoma, squamous cellGastrin-releasing peptide receptorHuman papillomavirusOncogenesPapillomavirus infectionsUterine cervical dysplasiaUterine cervical neoplasmsSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Martina Lichtenfels
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Review Article03-18-2025
Low-level laser therapy for nipple trauma and pain during breastfeeding: systematic review and meta-analysis
- Maria Victória Candida Gaitero
,
- Ticiana Aparecida Alves de Mira
,
- Edna Jéssica Lima Gondim
,
- Simony Lira do Nascimento
,
- Fernanda Garanhani Surita
Abstract
Review ArticleLow-level laser therapy for nipple trauma and pain during breastfeeding: systematic review and meta-analysis
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo3
- Maria Victória Candida Gaitero
,
- Ticiana Aparecida Alves de Mira
,
- Edna Jéssica Lima Gondim
,
- Simony Lira do Nascimento
,
- Fernanda Garanhani Surita
Views149Abstract
Objective:
This study aimed to investigate the effect of low-level laser therapy (LLLT) on nipple trauma and pain during breastfeeding through a systematic review with a meta-analysis of selected studies.
Source of the data:
A thorough search was conducted on March 22, 2022, using the databases PubMed, SciELO, LILACS, PEDro, CINAHL, EMBASE, ScienceDirect, Scopus, Google Scholar, MEDLINE, the Cochrane Library, Clinical Trials, Web of Science, TRIP, DARE, and ProQuest. The search terms included various combinations of low-level laser therapy, nipple pain, nipple trauma, and breastfeeding.
Studies selection:
Out of 107 articles identified, only three controlled and randomized clinical trials was included. The extracted data encompassed breast and trauma characteristics, treatment types, outcomes (pain and healing process), evaluation tools, LLLT usage, laser brand, and parameters.
Data collection:
Data extraction was performed using RAYYAN for systematic reviews. The risk of bias in the studies was evaluated.
Data synthesis:
Pain was measured using the visual analog scale (VAS). The included studies did not use validated tools for assessing physical conditions. All studies employed LLLT with a 660-nm wavelength, though there were variations in equipment power, energy dose, and application methods. The meta-analysis revealed an average difference of −0.60 points (95% CI: −1.52 to 0.31) in the VAS pain scores between the LLLT and control groups. No heterogeneity was observed among the studies (I2=0%), indicating no significant difference in pain relief between LLLT (red light) and control groups.
Conclusion:
LLLT may offer a promising option for managing breastfeeding-related complications, though further research is required.
Key-words Breast feedingLaser therapyLow level light therapyLow-level laserNipple painNipple traumaNipplesSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Maria Victória Candida Gaitero
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Review Article03-18-2025
Clinical repercussions of statin use during pregnancy: a review of the literature
- Joan Lins Serafim
,
- Pedro Lucas Santos de Menezes Teles
,
- Amanda Katharinne Souza Lima
,
- Jéssica dos Santos Coelho
,
- Paloma Luna Maranhão Conrado
,
[ … ], - George Alessandro Maranhão Conrado
Abstract
Review ArticleClinical repercussions of statin use during pregnancy: a review of the literature
Revista Brasileira de Ginecologia e Obstetrícia. 2025;47:e-rbgo2
- Joan Lins Serafim
,
- Pedro Lucas Santos de Menezes Teles
,
- Amanda Katharinne Souza Lima
,
- Jéssica dos Santos Coelho
,
- Paloma Luna Maranhão Conrado
,
- Valda Lúcia Moreira Luna
,
- Pauliana Valéria Machado Galvão
,
- George Alessandro Maranhão Conrado
Views127Abstract
Statins are the most widely used pharmacological class for treating hyperlipidemia, although they are contraindicated during pregnancy. This study aims to demonstrate the clinical effects of statins in pregnant women through an interactive review. Fifteen original articles were selected, in English or Portuguese, within of five years. Statins have not been associated with the development of fetal malformations and their use may be useful in preventing unfavorable cardiovascular outcomes, with the potential to reduce oxidative stress and angiogenic dysfunction. However, the use of statins to prevent pre-eclampsia in humans has not been properly clarified and further studies are needed. Pravastatin is considered safer than statins for use during pregnancy.
Key-words Antihypertensive agentsHydroxymethylglutaryl-CoA reductase inhibitorsPravastatinPre-eclampsiaPregnancyPregnant womanSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Joan Lins Serafim
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