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Review Article12-04-2024
Female genital tract microbiome: the influence of probiotics on assisted reproduction
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo82
Views241This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleFemale genital tract microbiome: the influence of probiotics on assisted reproduction
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo82
Views241Abstract
Assisted reproductive technology (ART) has been evolving since 1978, with the number of techniques performed increasing over the years. Despite continued advances, some couples continue to have difficulties getting pregnant, and it has recently been considered that the microbiome of the female genital tract (FGT) may influence embryo implantation and the establishment of pregnancy. This review aims to evaluate the role of probiotics on reproductive outcomes in infertile women on ART. A search throughout medical databases was performed, and six articles met the criteria. Five studies showed improvements in pregnancy rates, with only one demonstrating statistical significance. One article showed no improvement but reported a statistically significant reduction in the miscarriage rate in the probiotic group. Further research is needed to evaluate the true potential of probiotics, namely to assess whether they effectively modulate the FGT microbiome and if these changes are maintained over time.
Key-words Abortion, spontaneousEmbryo implantationGenitalia, femaleInfertility, femalePregnancy outcomePregnancy rateProbioticsReproductive techniques, assisted, MicrobiotaSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article12-04-2024
Prevalence and factors associated with non-alcoholic fatty liver disease among women with polycystic ovary syndrome
- Maria Elisa Franciscatto
,
- Juliana Bosso Taniguchi
,
- Raquel Wohlenberg
,
- Isadora Luísa Riedi
,
- Karen Oppermann
Abstract
Original ArticlePrevalence and factors associated with non-alcoholic fatty liver disease among women with polycystic ovary syndrome
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo81
- Maria Elisa Franciscatto
,
- Juliana Bosso Taniguchi
,
- Raquel Wohlenberg
,
- Isadora Luísa Riedi
,
- Karen Oppermann
Views286Abstract
Objective:
To verify the prevalence and factors associated with Non-Alcoholic Fatty Liver Disease (NAFLD) among women with Polycystic Ovary Syndrome (PCOS).
Methods:
A cross-sectional study was conducted with 53 patients with PCOS. The diagnosis of PCOS followed the Rotterdam criteria. The diagnosis of NAFLD was made through US showing hepatic steatosis, excluding significant alcohol consumption and chronic liver disease. The following variables were compared between the groups of women with and without NAFLD: age, race, anthropometric data, blood pressure levels, liver enzymes, glycemic and lipid profiles, total testosterone, presence of hirsutism, and metabolic syndrome (MS). Variables were compared between the groups using T-test, Mann-Whitney, and Chi-square tests.
Results:
Among 53 patients with PCOS, 50.9% had NAFLD. The NAFLD group had higher weight (p=0.003), BMI (p=0.001), waist circumference (p≤0.001), fasting glucose (p=0.021), HbA1C% (p=0.028), triglycerides (p=0.023), AST (p=0.004), ALT (p=0.001), higher prevalence of MS (p=0.004), and lower levels of HDL cholesterol (p=0.043). The other variables did not differ between the groups. Both groups were predominantly of caucasian race, and there was no significant difference in age.
Conclusion:
The prevalence of NAFLD among patients with PCOS was 50.9%. Metabolic and hepatic enzyme abnormalities were more prevalent in this group compared to the group without the disease. Obesity tripled the prevalence of NAFLD.
Key-words Alcohol drinkingHyperandrogenismmetabolic syndromenon-alcoholic fatty liver diseaseObesityPolycystic ovary syndromeWaist circumferenceSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Maria Elisa Franciscatto
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Review Article12-04-2024
Zuranolone for postpartum depression: a systematic review and meta-analysis of two randomized studies
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo79
Abstract
Review ArticleZuranolone for postpartum depression: a systematic review and meta-analysis of two randomized studies
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo79
Views303See moreAbstract
Objective:
To evaluate the maternal outcomes in women with postpartum depression using zuranolone, the first oral medication indicated to treat postpartum depression.
Methods:
We conducted a systematic search in September 2023, on Pubmed, Embase and Cochrane Trials. We included randomized controlled trials comparing the effectiveness and safety of zuranolone versus placebo in women with postpartum depression. No time or language restrictions were applied. 297 results were retrieved, of which 11 papers were selected and fully reviewed by two authors. Review Manager 5 was used for statistical analysis and Cochrane Risk-of-bias tool for randomized trials was applied for quality assessment.
Results:
We included 2 studies, with 346 women, of whom 174 (50.2%) were treated with zuranolone. Zuranolone was significantly associated to an improvement of Clinical Global Impression response rate; Hamilton Depression Rating Scale 15 days and 45-day remission, 3-day, 15-day, and 45-day symptom remission, and reduction in the dose of antidepressants. As for safety outcomes, it was noticed that zuranolone increases sedation risk, which can be dose related. No significant differences were found for other adverse events.
Conclusion:
These findings suggest that zuranolone might present a safe and effective medication for out-of-hospital treatment of PPD. Sedation effects need to be further assessed.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article12-04-2024
Self-medication among pregnant women in comparison to the general population: a scoping review of the main characteristics
- Gabriela Pereira
,
- Cinthia Madeira de Souza
,
- Amanda Canato Ferracini
,
- Fernanda Garanhani Surita
,
- Sherif Eltonsy
,
[ … ], - Priscila Gava Mazzola
Abstract
Review ArticleSelf-medication among pregnant women in comparison to the general population: a scoping review of the main characteristics
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo77
- Gabriela Pereira
,
- Cinthia Madeira de Souza
,
- Amanda Canato Ferracini
,
- Fernanda Garanhani Surita
,
- Sherif Eltonsy
,
- Priscila Gava Mazzola
Views295Abstract
Objective:
An in-depth evaluation of the published evidence is needed on self-medication, specifically the evidence focusing on vulnerable groups, such as pregnant women. This scoping review aims to provide an overview of the differences in self-medication prevalence and study characteristics among different groups, while identifying gaps in the literature.
Methods:
A literature search was performed in PubMed and Web of Science, including articles published in the last 10 years for the pregnant women group (PWG) and the general population group (GPG). Data on study design, self-medication prevalence, medications used, and other variables were collected, tabulated, and summarized.
Results:
From 2888 screened articles, 75 were considered including 108,559 individuals. The self-medication (SM) in the PWG ranged from 2.6 to 72.4% and most studies had an SM prevalence between 21 and 50% and in the GPG, 32 from 50 studies had a SM prevalence higher than 50%. The reviewed studies varied considerably in methodology, requiring careful interpretation. While most of the studies assessed self-medication during the entire pregnancy, self-medication definition was often inconsistent between studies. Acetaminophen was the most used medication and headache was the most frequent symptom leading to self-medication initiation in the PWG.
Conclusions:
Self-medication among pregnant women showed a lower prevalence when compared to the general population. The medications used and symptoms reported were similar between groups. However, methodological differences must be carefully considered. Pregnant women should carefully follow their physicians’ advice before initiating self-medication to avoid preventable maternal and fetal adverse effects.
Key-words drug-related side effects and adverse reactionsMedication usePregnant womenSelf-medicationSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Gabriela Pereira
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FEBRASGO POSITION STATEMENT11-25-2024
Nonclassic congenital adrenal hyperplasia due to 21-hydroxylase deficiency in women: diagnosis and treatment: Number 11 – 2024
- Andrea Prestes Nácul
,
- Ana Carolina Japur Sá Rosa e Silva
,
- Daniela Angerame Yela
,
- Sebastião Freitas de Medeiros
,
- José Maria Soares Júnior
,
[ … ], - Cristina Laguna Benetti-Pinto
Abstract
FEBRASGO POSITION STATEMENTNonclassic congenital adrenal hyperplasia due to 21-hydroxylase deficiency in women: diagnosis and treatment: Number 11 – 2024
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS11
- Andrea Prestes Nácul
,
- Ana Carolina Japur Sá Rosa e Silva
,
- Daniela Angerame Yela
,
- Sebastião Freitas de Medeiros
,
- José Maria Soares Júnior
,
- Gabriela Pravatta Rezende Antoniassi
,
- Lia Cruz da Costa Damásio
,
- Técia Maria de Oliveira Maranhão
,
- Gustavo Arantes Rosa Maciel
,
- Cristina Laguna Benetti-Pinto
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Andrea Prestes Nácul
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FEBRASGO POSITION STATEMENT11-14-2024
Challenges and strategies in adolescent vaccination: Number 12 – 2024
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS12
Abstract
FEBRASGO POSITION STATEMENTChallenges and strategies in adolescent vaccination: Number 12 – 2024
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-FPS12
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Letter to the Editor10-23-2024
The gynecologist and cancer in women
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo92
Views163This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Letter to the EditorThe gynecologist and cancer in women
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo92
Views163Cervical cancer continues to claim an alarming number of victims around the world, especially among poor women. In Brazil, in 2022, an incidence of 16.3/100,000 women was recorded,() with a projection for 2023 of 17,010 new cases, corresponding to a rate of 15.38/100,000, representing 7% of tumors in women.In the Brazilian reality, where there is […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article10-23-2024
Nipple-sparing mastectomy in young versus elderly patients
- Antônio Luiz Frasson
,
- Isabela Miranda
,
- Betina Vollbrecht
,
- Carolina Malhone
,
- Ana Beatriz Falcone
,
[ … ], - Martina Lichtenfels
Abstract
Original ArticleNipple-sparing mastectomy in young versus elderly patients
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo90
- Antônio Luiz Frasson
,
- Isabela Miranda
,
- Betina Vollbrecht
,
- Carolina Malhone
,
- Ana Beatriz Falcone
,
- Fernanda Barbosa
,
- Francisco Pimentel Cavalcante
,
- Martina Lichtenfels
Views176See moreAbstract
Objective:
In this study, we compared indications and outcomes of 115 young (< 40 years) versus 40 elderly (> 60 years) patients undergoing nipple-sparing mastectomy (NSM) as risk-reducing surgery or for breast cancer (BC) treatment.
Methods:
Between January 2004 and December 2018, young and elderly patients undergoing NSM with complete data from at least 6 months of follow-up were included.
Results:
BC treatment was the main indication for NSM, observed in 85(73.9%) young versus 33(82.5%) elderly patients, followed by risk-reducing surgery in 30(26.1%) young versus 7(17.5%) elderly patients. Complication rates did not differ between the age groups. At a median follow-up of 43 months, the overall recurrence rate was higher in the younger cohort (p = 0.04). However, when stratified into local, locoregional, contralateral, and distant metastasis, no statistical difference was observed. During the follow-up, only 2(1.7%) young patients died.
Conclusion:
Our findings elucidate a higher recurrence rate of breast cancer in younger patients undergoing NSM, which may correlate with the fact that age is an independent prognostic factor. High overall survival and low complication rates were evidenced in the two groups showing the safety of NSM for young and elderly patients.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Antônio Luiz Frasson
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Thesis Abstract04-04-2007
Effect of raloxifene on the vaginal epithelium of postmenopausal women
Revista Brasileira de Ginecologia e Obstetrícia. 2007;29(1):57-57
Abstract
Thesis AbstractEffect of raloxifene on the vaginal epithelium of postmenopausal women
Revista Brasileira de Ginecologia e Obstetrícia. 2007;29(1):57-57
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Letter to the Editor12-21-2020Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(10):676-678
Views77This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Letter to the EditorRevista Brasileira de Ginecologia e Obstetrícia. 2020;42(10):676-678
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Thesis Abstract04-10-2005
Evaluation of nitric oxide effects on embryo development in mice in vivo and in vitro
Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(11):706-706
Abstract
Thesis AbstractEvaluation of nitric oxide effects on embryo development in mice in vivo and in vitro
Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(11):706-706
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Thesis Abstract04-13-2005
Influence of hypothyalamic obesity on type 2 Diabetes mellitus in successive generations of female Wistar rats
Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(12):779-779
Abstract
Thesis AbstractInfluence of hypothyalamic obesity on type 2 Diabetes mellitus in successive generations of female Wistar rats
Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(12):779-779
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
07-04-2003
Estudo exploratório: ultra-sonografia, ecocardiografia fetal e resultados perinatais em gestantes portadoras do HIV em uso de terapia anti-retroviral
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(2):136-136
Abstract
Estudo exploratório: ultra-sonografia, ecocardiografia fetal e resultados perinatais em gestantes portadoras do HIV em uso de terapia anti-retroviral
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(2):136-136
DOI 10.1590/S0100-72032003000200011
Views42RESUMO DE TESE Estudo exploratório: ultra-sonografia, ecocardiografia fetal e resultados perinatais em gestantes portadoras do HIV em uso de terapia anti-retroviral […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Thesis Abstract10-14-2004
Gene polymorphisms in preeclampsia
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):584-584
Abstract
Thesis AbstractGene polymorphisms in preeclampsia
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(7):584-584
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Thesis Abstract03-11-2007
Predictive model for the risk of malignancy in solid breast nodules based on the ultra-sonography
Revista Brasileira de Ginecologia e Obstetrícia. 2007;29(12)
Abstract
Thesis AbstractPredictive model for the risk of malignancy in solid breast nodules based on the ultra-sonography
Revista Brasileira de Ginecologia e Obstetrícia. 2007;29(12)
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Letter to the Editor10-01-2018
Comments on: Conservative Surgical Treatment of a Case of Placenta Accreta
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(10):654-655
Abstract
Letter to the EditorComments on: Conservative Surgical Treatment of a Case of Placenta Accreta
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(10):654-655
Views76Dear Editor,Placenta accreta describes pathological adherence or invasion of the placenta to the myometrium. It may be a consequence of any procedure affecting the integrity of the uterine lining. The incidence is rising due to increase in the rate of cesarean delivery, which is the major risk factor. Published guidelines recommend delivery with planned cesarean […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Original Article11-01-2018
Obstetric Outcomes among Syrian Refugees: A Comparative Study at a Tertiary Care Maternity Hospital in Turkey
- Sule Ozel,
- Selen Yaman,
- Hatice Kansu-Celik,
- Necati Hancerliogullari,
- Nurgul Balci, [ … ],
- Yaprak Engin-Ustun
Views174This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleObstetric Outcomes among Syrian Refugees: A Comparative Study at a Tertiary Care Maternity Hospital in Turkey
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(11):673-679
- Sule Ozel,
- Selen Yaman,
- Hatice Kansu-Celik,
- Necati Hancerliogullari,
- Nurgul Balci,
- Yaprak Engin-Ustun
Views174See moreAbstract
Objective
The aim of this study was to analyze and compare obstetric and neonatal outcomes between Syrian refugees and ethnic Turkish women.
Methods
Retrospective, observational study. A total of 576 Syrian refugees and 576 ethnic Turkish women were included in this study, which was conducted between January 2015 and December 2015 at a tertiary maternity training hospital in Ankara, Turkey. The demographic characteristics, obstetric and neonatal outcomes were compared. The primary outcomes were pregnancy outcomes and cesarean rates between the groups
Results
The mean age was significantly lower in the refugee group (p< 0.001). Mean gravidity, proportion of adolescent pregnancies, proportion of pregnant women aged 12 to 19 years, and number of pregnancies at < 18 years were significantly higher among the refugee women (p< 0.001). Rates of antenatal follow-up, double testing, triple testing, gestational diabetes mellitus (GDM) screening, and iron replacement therapy were significantly lower in the refugee group (p< 0.001). The primary Cesarean section rate was significantly lower in the refugee group (p= 0.034). Pregnancies in the refugee group were more complicated, with higher rates of preterm delivery (< 37 weeks), preterm premature rupture of membranes (PPROM), and low birth weight (< 2,500 g) when compared with the control group (4.2% versus 0.7%, p< 0.001; 1.6% versus 0.2%, p= 0.011; and 12% versus 5.8%, p< 0.001, respectively). Low education level (odds ratio [OR] = 1.7, 95% confidence interval [CI] = 0.5–0.1), and weight gain during pregnancy (OR = 1.7, 95% CI = 0.5–0.1) were found to be significant indicators for preterm birth/PPROM and low birthweight.
Conclusion
Syrian refugees had increased risks of certain adverse obstetric outcomes, including preterm delivery, PPROM, lower birth weight, and anemia. Several factors may influence these findings; thus, refugee women would benefit from more targeted care during pregnancy and childbirth.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Editorial09-01-2018
Maternal Mortality in Brazil: Proposals and Strategies for its Reduction
- Rodolfo Carvalho Pacagnella,
- Marcos Nakamura-Pereira,
- Flavia Gomes-Sponholz,
- Regina Amélia Lopes Pessoa de Aguiar,
- Gláucia Virginia de Queiroz Lins Guerra, [ … ],
- Olímpio Barbosa de Moraes Filho
Views222This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
EditorialMaternal Mortality in Brazil: Proposals and Strategies for its Reduction
Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(9):501-506
- Rodolfo Carvalho Pacagnella,
- Marcos Nakamura-Pereira,
- Flavia Gomes-Sponholz,
- Regina Amélia Lopes Pessoa de Aguiar,
- Gláucia Virginia de Queiroz Lins Guerra,
- Carmen Simone Grilo Diniz,
- Brenno Belazi Nery de Souza Campos,
- Eliana Martorano Amaral,
- Olímpio Barbosa de Moraes Filho
Views222Maternal mortality is one of the health indicators that most reflect the social conditions of women. The inequities observed in this indicator between high- and low-income countries and among regions in the same country are explained by differences in the provision, in the access, and in the quality of obstetric care and of family planning. […]See moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article06-27-2019
Quality of Life among University Students with Premenstrual Syndrome
- Fernanda Figueira Victor,
- Ariani Impieri Souza,
- Cynthia Danúbia Tavares Barreiros,
- João Lucas Nunes de Barros,
- Flavia Anchielle Carvalho da Silva, [ … ],
- Ana Laura Carneiro Gomes Ferreira
Views265This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleQuality of Life among University Students with Premenstrual Syndrome
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(5):312-317
- Fernanda Figueira Victor,
- Ariani Impieri Souza,
- Cynthia Danúbia Tavares Barreiros,
- João Lucas Nunes de Barros,
- Flavia Anchielle Carvalho da Silva,
- Ana Laura Carneiro Gomes Ferreira
Views265Abstract
Objective
To evaluate the quality of life among university students with premenstrual syndrome (PMS).
Methods
The cross-sectional study was conducted at the Faculdade Pernambucana de Saúde, in Recife, Brazil, between August 2016 and July 2017. Sociodemographic, gynecological, and lifestyle variables, and PMS occurrence, were investigated among 642 students. The short form of the World Health Organization Quality of Life (WHOQOL Bref) questionnaire was used to evaluate four domains of the quality of life of the students: physical, mental, social relationships, and environmental. The American College of Obstetricians and Gynecologists’ criteria were used to define PMS.
Results
Of the 642 students, 49.9% had PMS, 23.3% had mild PMS and 26.6% had premenstrual dysphoric disorder (PMDD). Most of the students were between 18 and 24 years old, had regular menstrual cycles, and practiced physical activity. Regarding the physical and mental domains of the WHOQOL-Bref questionnaire, a statisticallysignificant difference was observed between the students who did not have and those who had mild or PMDD (p < 0.001). A difference was also found between the students who did not have PMS and those who had mild PMS in the social relationships (p = 0.001) and environmental domains (p = 0.009).
Conclusion
Mild PMS and PMDD are prevalent among university students on healthrelated courses, and the syndrome can affect the students’ self-assessment of all the domains of quality of life.
Key-words medical studentMenstruation disturbancespremenstrual dysphoric disorderPremenstrual syndromeQuality of lifeSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article06-01-2016
Selective Episiotomy: Indications, Techinique, and Association with Severe Perineal Lacerations
Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(6):301-307
Views197This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticleSelective Episiotomy: Indications, Techinique, and Association with Severe Perineal Lacerations
Revista Brasileira de Ginecologia e Obstetrícia. 2016;38(6):301-307
Views197See moreAbstract
Introduction
Episiotomy is a controversial procedure, especially because the discussion that surrounds it has gone beyond the field of scientific debate, being adopted as an indicator of the “humanization of childbirth”. The scientific literature indicates that episiotomy should not be performed routinely, but selectively.
Objectives
To review the literature in order to assess whether the implementation of selective episiotomy protects against severe perineal lacerations, the indications for the procedure, and the best technique to perform it.
Methods
A literature search was performed in PubMed using the terms episiotomy or perineal lacerations, and the filter clinical trial. The articles concerning the risk of severe perineal lacerations with or without episiotomy, perineal protection, or episiotomy techniques were selected.
Results
A total of 141 articles were identified, and 24 of them were included in the review. Out of the 13 studies that evaluated the risk of severe lacerations with and without episiotomy, 5 demonstrated a protective role of selective episiotomy, and 4 showed no significant differences between the groups. Three small studies confirmed the finding that episiotomy should be performed selectively and not routinely, and one study showed that midline episiotomy increased the risk of severe lacerations. The most cited indications were primiparity, fetal weight greater than 4 kg, prolonged second stage, operative delivery, and shoulder dystocia. As for the surgical technique, episiotomies performed with wider angles (> 40°) and earlier in the second stage (before “crowning “) appeared to be more protective.
Conclusions
Selective episiotomy decreases the risk of severe lacerations when compared with the non-performance or the performance of routine episiotomy. The use of a proper surgical technique is fundamental to obtain better results, especially in relation to the angle of incision, the distance from the vaginal introitus, and the correct timing for performing the procedure. Not performing the episiotomy when indicated or not applying the correct technique may increase the risk of severe perineal lacerations.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Review Article08-01-2017
Physical Activity during Pregnancy: Recommendations and Assessment Tools
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(8):424-432
Views236This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Review ArticlePhysical Activity during Pregnancy: Recommendations and Assessment Tools
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(8):424-432
Views236See moreAbstract
The literature that supports and recommends the practice of exercise during pregnancy is extensive.However, although a more complete research on ways to evaluate the physical activity performedby pregnant women has been perfomed, it is found that there is no gold standard and that the articles in the area are inconclusive. Thus, the objective of the present article is to review relevant aspects, such as, technique and applicability of the different methods for the assessment of physical activity during pregnancy to providemore reliable and safe information for health professionals to encourage their pregnant patients to engage in the practice of physical activity. This review concluded that all tools for the analysis of physical activity have limitations. Thus, it is necessary to establish the objectives of evaluation in an appropriate manner, as well as to determine their viability and costeffectiveness for the population under study.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article02-01-2017
Predictors of cesarean delivery in pregnant women with gestational diabetes mellitus
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(2):60-65
Views231This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticlePredictors of cesarean delivery in pregnant women with gestational diabetes mellitus
Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(2):60-65
Views231See moreAbstract
Purpose
The aim of this study was to evaluate which risk factors may lead patients with gestational diabetes mellitus to cesarean delivery.
Methods
This was a retrospective, descriptive study. The subjects of the study were pregnant women with gestational diabetes mellitus attending a public maternity hospital in the south of Brazil. The primary outcomes assessed were based on maternal and fetal characteristics. The data were correlated using an odds ratio (OR) with a 95% confidence interval (95%CI), calculated using multinomial logistic regression.
Results
A total of 392 patients with gestational diabetes mellitus were analyzed, and 57.4% of them had cesarean deliveries. Among the maternal characteristics, the mean age of the patients and the pregestational body mass index were greater when a cesarean delivery was performed (p = 0.029 and p < 0.01 respectively). Gestational age at birth, newborn weight, weight class according to gestational age, and Apgar score were not significant. The analysis of the OR showed that the chance of cesarean delivery was 2.25 times (95%CI = 1.49-2.39) greater if the pregnant woman was obese, 4.6 times (95%CI = 3.017-7.150) greater if she was a primigravida, and 5.2 times (95% CI = 2.702-10.003) greater if she had a previous cesarean delivery. The other parameters analyzed showed no differences.
Conclusion
The factors that led to an increase in the occurrence of cesarean deliveries included history of a prior cesarean section, first pregnancy, and obesity.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Editorial12-01-2015
Maternal mortality and the new objectives of sustainable development (2016-2030)
Revista Brasileira de Ginecologia e Obstetrícia. 2015;37(12):549-551
Views104This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
EditorialMaternal mortality and the new objectives of sustainable development (2016-2030)
Revista Brasileira de Ginecologia e Obstetrícia. 2015;37(12):549-551
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Original Article08-21-2015
Increased oxidative stress markers may be a promising indicator of risk for primary ovarian insufficiency: a cross-sectional case control study
- Aytekin Tokmak,
- Gülçin Yıldırım,
- Esma Sarıkaya,
- Mehmet Çınar,
- Nihal Boğdaycıoğlu, [ … ],
- Nafiye Yılmaz
Views90This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleIncreased oxidative stress markers may be a promising indicator of risk for primary ovarian insufficiency: a cross-sectional case control study
Revista Brasileira de Ginecologia e Obstetrícia. 2015;37(9):411-416
DOI 10.1590/SO100-720320150005397
- Aytekin Tokmak,
- Gülçin Yıldırım,
- Esma Sarıkaya,
- Mehmet Çınar,
- Nihal Boğdaycıoğlu,
- Fatma Meriç Yılmaz,
- Nafiye Yılmaz
Views90See morePURPOSE:
The aim of this study was to evaluate serum levels of inducible nitric oxide synthase (INOS), myeloperoxidase (MPO), total antioxidant status (TAS), and total oxidative status (TOS) in women with primary ovarian insufficiency (POI) and to compare them with healthy fertile women. We also examined the possible risk factors associated with POI.
METHODS:
This cross-sectional case control study was conducted in Zekai Tahir Burak Women’s Health Education and Research Hospital. The study population consisted of 44 women with POI (study group) and 36 healthy fertile women (control group). In all patients, serum levels of INOS, MPO, TAS, and TOS were determined. INOS and MPO levels were measured by enzyme-linked immunosorbent assay whereas colorimetric method was used for evaluating TAS and TOS levels. Age, body mass index (BMI), obstetric history, smoking status, family history, comorbidities, sonographic findings, complete blood count values, C-reactive protein and baseline hormone levels were also analyzed. Student’s t-test or Mann-Whitney U test was used to compare continuous variables between the groups; categorical data were evaluated by using Pearson χ2 or Fisher exact test, when appropriate. Binary logistic regression method was used to identify risk factors for POI.
RESULTS:
We found significantly elevated levels of INOS (234.1±749.5 versus133.8±143.0; p=0.005), MPO (3,438.7±1,228.6 versus 2,481.9±1,230.1; p=0.001), and TOS (4.3±1.4 versus 3.6±1.4; p=0.02) in the sera of the study group when compared to the BMI-age matched control group. However, difference in serum levels of TAS were not significant between the 2 groups (1.7±0.2 versus 1.6±0.2; p=0.15). Logistic regression method demonstrated that BMI <25 kg/m2, nulliparity, family history of POI, smoking, and elevated serum levels of INOS, MPO, and TOS were independent risk factors for POI.
CONCLUSION:
We found an increase in INOS, MPO, and TOS in women with POI. These serum markers may be promising in early diagnosis of POI. Further large-scale studies are required to determine whether oxidative stress markers have a role in diagnosing POI.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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