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Trabalhos Originais
Ultrasonographic markers for fetal congenital toxoplasmosis
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(5):377-382
08-04-2004
Summary
Trabalhos OriginaisUltrasonographic markers for fetal congenital toxoplasmosis
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(5):377-382
08-04-2004DOI 10.1590/S0100-72032004000500006
Views66See moreOBJECTIVE: to describe ultrasonographic alterations in fetuses infected with Toxoplasma gondii, correlating them with neonatal prognosis. METHODS: between June 1997 and May 2003, 150 pregnant women with suspected toxiplasmosis were examined. Acute infection was confirmed in 72 (48%) of these pregnant women and congenital toxoplasmosis was diagnosed in 12 (16%) fetuses. Prenatal diagnosis was established by polymerase chain reaction in the amniotic fluid. All the patients received antiparasitic therapy. Ultrasound examination was performed every fortnight and all the infants were evaluated during their first year of life. RESULTS: ultrasonographic changes were observed in eight fetuses. All of them showed symmetric bilateral ventricular enlargement that was associated with periventricular calcifications in five cases. Other changes as hepatic calcification, hepatomegaly, polyhydramnium, and pericardial effusion were less frequent. Among these fetuses, four were stillborn and three showed sequelae (chorioretinitis and neuro-psychomotor retardation). The four fetuses that showed normal ultrasonography had a satisfactory development. CONCLUSION: There was a high incidence of ultrasonographic changes in fetuses with congenital toxoplasmosis, mainly brain damage. Other changes as hepatomegaly and pericardial effusion were less frequent and were related to a systemic infection. The prognosis of these fetuses seems to be correlated with the presence of these lesions mainly because they had high mortality ratio and among the survivors the incidence of sequelae was high. The non-symptomatic fetuses evolved in a favorable way without developing sequelae. These results highlight the value of ultrasonographic examination of these fetuses in order to establish a prognosis and allow the elaboration of a suitable post-natal procedure.
Views66
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisUltrasonographic markers for fetal congenital toxoplasmosis
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(5):377-382
08-04-2004DOI 10.1590/S0100-72032004000500006
Views66See moreOBJECTIVE: to describe ultrasonographic alterations in fetuses infected with Toxoplasma gondii, correlating them with neonatal prognosis. METHODS: between June 1997 and May 2003, 150 pregnant women with suspected toxiplasmosis were examined. Acute infection was confirmed in 72 (48%) of these pregnant women and congenital toxoplasmosis was diagnosed in 12 (16%) fetuses. Prenatal diagnosis was established by polymerase chain reaction in the amniotic fluid. All the patients received antiparasitic therapy. Ultrasound examination was performed every fortnight and all the infants were evaluated during their first year of life. RESULTS: ultrasonographic changes were observed in eight fetuses. All of them showed symmetric bilateral ventricular enlargement that was associated with periventricular calcifications in five cases. Other changes as hepatic calcification, hepatomegaly, polyhydramnium, and pericardial effusion were less frequent. Among these fetuses, four were stillborn and three showed sequelae (chorioretinitis and neuro-psychomotor retardation). The four fetuses that showed normal ultrasonography had a satisfactory development. CONCLUSION: There was a high incidence of ultrasonographic changes in fetuses with congenital toxoplasmosis, mainly brain damage. Other changes as hepatomegaly and pericardial effusion were less frequent and were related to a systemic infection. The prognosis of these fetuses seems to be correlated with the presence of these lesions mainly because they had high mortality ratio and among the survivors the incidence of sequelae was high. The non-symptomatic fetuses evolved in a favorable way without developing sequelae. These results highlight the value of ultrasonographic examination of these fetuses in order to establish a prognosis and allow the elaboration of a suitable post-natal procedure.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Evaluation of risk for preterm delivery by measurement of uterine cervix and cervical gland area
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(3):193-200
07-05-2004
Summary
Trabalhos OriginaisEvaluation of risk for preterm delivery by measurement of uterine cervix and cervical gland area
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(3):193-200
07-05-2004DOI 10.1590/S0100-72032004000300004
Views76See morePURPOSE: to verify the prevalence of two sonographic findings, the cervical gland area (CGA) feature and the cervical length of less than 20 mm, and to compare these with the risk for premature delivery in pregnant women between 21 and 24 weeks' gestation. METHOD: this was a prospective, cross-sectional study in which 361 women were consecutively examined by transvaginal ultrasonography. Müllerian or other malformations, multiple gestations, fetal death, olygo- or polyhydramnios, marginal placenta previa, and conization, cerclage, amputation or other surgical procedures in the cervix, prior to or during pregnancy, were exclusion criteria. After the abdominal ultrasonographic morphological examination, we used transvaginal ultrasonography to measure the cervical length and to observe the presence of hyper- or hypoechoic area next to the endocervical canal, a feature characteristic of endocervical epithelium glands which is called CGA (cervical gland area). Qualitative variables are expressed as absolute and relative frequency. Quantitative variables are expressed as mean, median, standard deviation, minimum, and maximum values. Association between qualitative variables was detected by the c² test or by the Fisher exact test. For each variable, the relative risk and the 95% confidence interval (CI) were calculated. Logistic regression analysis was used to calculate the predictive values for premature delivery. Significance level was 95% (alpha = 5%), with descriptive (p) values equal or lower than 0.05 considered significant. RESULTS: spontaneous preterm delivery occurred in 5.0% of the patients. Cervical length was up to 20 mm in 3.3% of all studied patients and in 27.8% of those who delivered spontaneously before the end of the pregnancy. Absence of the CGA was detected in 2.8% of all patients and in 44.4% of the women who eventually developed spontaneous preterm labor. There was a statistically significant association of absence of CGA with short cervical length (p<0.001). Absence of CGA was strongly associated with spontaneous preterm delivery (relative risk of 28.57, 95% CI 14.40-56.68). CONCLUSION: the absent CGA feature is a new morphological ultrasonographic parameter that is useful in the prediction of spontaneous preterm delivery in single gestations. Our results show that the parameter can be used as an indicator of risk for premature delivery, to be confirmed by future research.
Views76This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisEvaluation of risk for preterm delivery by measurement of uterine cervix and cervical gland area
Revista Brasileira de Ginecologia e Obstetrícia. 2004;26(3):193-200
07-05-2004DOI 10.1590/S0100-72032004000300004
Views76See morePURPOSE: to verify the prevalence of two sonographic findings, the cervical gland area (CGA) feature and the cervical length of less than 20 mm, and to compare these with the risk for premature delivery in pregnant women between 21 and 24 weeks' gestation. METHOD: this was a prospective, cross-sectional study in which 361 women were consecutively examined by transvaginal ultrasonography. Müllerian or other malformations, multiple gestations, fetal death, olygo- or polyhydramnios, marginal placenta previa, and conization, cerclage, amputation or other surgical procedures in the cervix, prior to or during pregnancy, were exclusion criteria. After the abdominal ultrasonographic morphological examination, we used transvaginal ultrasonography to measure the cervical length and to observe the presence of hyper- or hypoechoic area next to the endocervical canal, a feature characteristic of endocervical epithelium glands which is called CGA (cervical gland area). Qualitative variables are expressed as absolute and relative frequency. Quantitative variables are expressed as mean, median, standard deviation, minimum, and maximum values. Association between qualitative variables was detected by the c² test or by the Fisher exact test. For each variable, the relative risk and the 95% confidence interval (CI) were calculated. Logistic regression analysis was used to calculate the predictive values for premature delivery. Significance level was 95% (alpha = 5%), with descriptive (p) values equal or lower than 0.05 considered significant. RESULTS: spontaneous preterm delivery occurred in 5.0% of the patients. Cervical length was up to 20 mm in 3.3% of all studied patients and in 27.8% of those who delivered spontaneously before the end of the pregnancy. Absence of the CGA was detected in 2.8% of all patients and in 44.4% of the women who eventually developed spontaneous preterm labor. There was a statistically significant association of absence of CGA with short cervical length (p<0.001). Absence of CGA was strongly associated with spontaneous preterm delivery (relative risk of 28.57, 95% CI 14.40-56.68). CONCLUSION: the absent CGA feature is a new morphological ultrasonographic parameter that is useful in the prediction of spontaneous preterm delivery in single gestations. Our results show that the parameter can be used as an indicator of risk for premature delivery, to be confirmed by future research.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Evolution of doppler indices and velocities of the middle cerebral artery in fetuses of normal pregnant women
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(6):437-442
10-07-2003
Summary
Trabalhos OriginaisEvolution of doppler indices and velocities of the middle cerebral artery in fetuses of normal pregnant women
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(6):437-442
10-07-2003DOI 10.1590/S0100-72032003000600009
Views110See morePURPOSE: to study the evolution of the resistance and pulsatility indices, maximum velocity, final diastolic velocity and time of acceleration of the middle cerebral artery of fetuses between 22 and 38 weeks of gestation. METHODS: a prospective and longitudinal observational study was conducted on 33 fetuses of normal pregnant women evaluated between 22 and 38 weeks of pregnancy. The gestational age was determined on the basis of the date of the last menstruation and/or by ultrasound examination during the first trimester. Doppler ultrasound examination was performed by a single observer using an Image Point 1800 (Hewlett Packard) apparatus equipped with a multiple frequency transducer. For the acquisition of the Doppler tracing of the middle cerebral artery, the sample indicator was calibrated for a sample volume of 1 mm³ and placed on the anterior middle cerebral artery as close as possible to the skullcap. The insonation angle was kept between 5º and 19º and the filter was adjusted to a frequency of 50-100 Hz. The newborn infants were evaluated in order to confirm that the fetuses were vigorous and adequate for gestational age. RESULTS: the results obtained for the resistance and pulsatility indices revealed a 2nd-degree equation, representing a parabola whose values for the resistance index were 0.81 during the 22nd week and 0.75 during the 38th week. The pulsatility index was 1.59 during the 22nd week and 1.45 during the 38th week. Maximum systolic velocity increased progressively along pregnancy, with values of 26.3 cm/s during the 22nd week and 57.7 cm/s during the 38th week. Final diastolic velocity increased progressively from the 26th week (5.21 cm/s) to term (14.6 cm/s). Acceleration time increased significantly only between 26 and 30 weeks, with values of 0.04 s during the 26th week and 0.05 s during the 30th week. CONCLUSION: it was concluded that the evolution of the resistance and pulsatility indices and of maximum systolic velocity were similar to those of most studies described in the literature. Acceleration time presented few modifications during the evaluated gestational weeks.
Views110This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisEvolution of doppler indices and velocities of the middle cerebral artery in fetuses of normal pregnant women
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(6):437-442
10-07-2003DOI 10.1590/S0100-72032003000600009
Views110See morePURPOSE: to study the evolution of the resistance and pulsatility indices, maximum velocity, final diastolic velocity and time of acceleration of the middle cerebral artery of fetuses between 22 and 38 weeks of gestation. METHODS: a prospective and longitudinal observational study was conducted on 33 fetuses of normal pregnant women evaluated between 22 and 38 weeks of pregnancy. The gestational age was determined on the basis of the date of the last menstruation and/or by ultrasound examination during the first trimester. Doppler ultrasound examination was performed by a single observer using an Image Point 1800 (Hewlett Packard) apparatus equipped with a multiple frequency transducer. For the acquisition of the Doppler tracing of the middle cerebral artery, the sample indicator was calibrated for a sample volume of 1 mm³ and placed on the anterior middle cerebral artery as close as possible to the skullcap. The insonation angle was kept between 5º and 19º and the filter was adjusted to a frequency of 50-100 Hz. The newborn infants were evaluated in order to confirm that the fetuses were vigorous and adequate for gestational age. RESULTS: the results obtained for the resistance and pulsatility indices revealed a 2nd-degree equation, representing a parabola whose values for the resistance index were 0.81 during the 22nd week and 0.75 during the 38th week. The pulsatility index was 1.59 during the 22nd week and 1.45 during the 38th week. Maximum systolic velocity increased progressively along pregnancy, with values of 26.3 cm/s during the 22nd week and 57.7 cm/s during the 38th week. Final diastolic velocity increased progressively from the 26th week (5.21 cm/s) to term (14.6 cm/s). Acceleration time increased significantly only between 26 and 30 weeks, with values of 0.04 s during the 26th week and 0.05 s during the 30th week. CONCLUSION: it was concluded that the evolution of the resistance and pulsatility indices and of maximum systolic velocity were similar to those of most studies described in the literature. Acceleration time presented few modifications during the evaluated gestational weeks.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Comparison of ultrasonographic, hysteroscopic and histopathologic findings in women with postmenopausal uterine bleeding
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(4):229-235
09-04-2003
Summary
Trabalhos OriginaisComparison of ultrasonographic, hysteroscopic and histopathologic findings in women with postmenopausal uterine bleeding
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(4):229-235
09-04-2003DOI 10.1590/S0100-72032003000400002
Views68See morePURPOSE: to determine the association between ultrasonographic, hysteroscopic and histopathologic findings in women with postmenopausal uterine bleeding. METHODS: a retrospective, cross-sectional study was conducted enrolling 156 women with postmenopausal bleeding attended at the Diagnostic Center - IMIP during the period of January 1995 to December 2001. According to the results of the endometrial examination (ultrasound), the patients were classified as having an abnormal or normal finding depending on the cutoffs of 4 or 5 mm. The most common histologic and hysteroscopic findings were studied and classified as premalignant/malignant lesions (hyperplasia/endometrial cancer) or benign findings. These results were compared using the kappa index, to establish the agreement between these techniques. RESULTS: the frequency of endometrial thickening was 75.0 and 67.3% according to cutoffs of 4 mm and 5 mm, respectively. Hysteroscopic findings were atrophic endometrium in 59 (37.8%), endometrial polyp in 56 (35.9%), endometrial hyperplasia in 17 (10.9%), cancer in 16 (10.3%), still active endometrium in 1 (3,2), and other findings in 3 (1.9%). The two most frequent histopathologic findings were also atrophic endometrium (31.4%) and endometrial polyps (26,.3%), followed by scanty material (16.0%), endometrial cancer (10.9%), endometrial hyperplastic changes (9.0%), and others (6.4%). A good agreement between hysteroscopic and histopathologic findings was observed (kappa = 0.61). CONCLUSIONS: the frequency of endometrial thickening was 75.0 and 67.3% according to cutoffs of 4 mm and 5 mm, respectively. No premalignant or malignant lesions were missed when an endometrial cutoff of 4 mm was used. The most frequent hysteroscopic and histopathologic findings were atrophic endometrium and endometrial polyps and a good agreement between these findings was encountered.
Views68This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisComparison of ultrasonographic, hysteroscopic and histopathologic findings in women with postmenopausal uterine bleeding
Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(4):229-235
09-04-2003DOI 10.1590/S0100-72032003000400002
Views68See morePURPOSE: to determine the association between ultrasonographic, hysteroscopic and histopathologic findings in women with postmenopausal uterine bleeding. METHODS: a retrospective, cross-sectional study was conducted enrolling 156 women with postmenopausal bleeding attended at the Diagnostic Center - IMIP during the period of January 1995 to December 2001. According to the results of the endometrial examination (ultrasound), the patients were classified as having an abnormal or normal finding depending on the cutoffs of 4 or 5 mm. The most common histologic and hysteroscopic findings were studied and classified as premalignant/malignant lesions (hyperplasia/endometrial cancer) or benign findings. These results were compared using the kappa index, to establish the agreement between these techniques. RESULTS: the frequency of endometrial thickening was 75.0 and 67.3% according to cutoffs of 4 mm and 5 mm, respectively. Hysteroscopic findings were atrophic endometrium in 59 (37.8%), endometrial polyp in 56 (35.9%), endometrial hyperplasia in 17 (10.9%), cancer in 16 (10.3%), still active endometrium in 1 (3,2), and other findings in 3 (1.9%). The two most frequent histopathologic findings were also atrophic endometrium (31.4%) and endometrial polyps (26,.3%), followed by scanty material (16.0%), endometrial cancer (10.9%), endometrial hyperplastic changes (9.0%), and others (6.4%). A good agreement between hysteroscopic and histopathologic findings was observed (kappa = 0.61). CONCLUSIONS: the frequency of endometrial thickening was 75.0 and 67.3% according to cutoffs of 4 mm and 5 mm, respectively. No premalignant or malignant lesions were missed when an endometrial cutoff of 4 mm was used. The most frequent hysteroscopic and histopathologic findings were atrophic endometrium and endometrial polyps and a good agreement between these findings was encountered.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Assessment of Embryo Heart Rate in Early Pregnancy by Transvaginal Ultrasonography with Color and Pulsed Doppler
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(9):551-555
07-23-2000
Summary
Trabalhos OriginaisAssessment of Embryo Heart Rate in Early Pregnancy by Transvaginal Ultrasonography with Color and Pulsed Doppler
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(9):551-555
07-23-2000DOI 10.1590/S0100-72032000000900003
Views64See morePurpose: to evaluate the evolution in the embryo heart rate in the first trimester of pregnancy. Patients and Methods: in a prospective study 206 pregnant women were evaluated in the first trimester of pregnancy, by transvaginal color Doppler sonography, using Aloka, SSD-2000 apparatus, with a 5-MHz transvaginal transducer. All examinations were performed by the same examiner, with the determination of embryo heart rate. The patients were classified into groups according to the gestational age, in half-week intervals from the 5th week of pregnancy on. Pregnancy outcome was evaluated by ultrasonography at the end of second and third trimesters. Mean and standard deviation were determined for each evaluated gestational age. Results: it was possible to determine normal values for embryo heart rate. Mean embryo heart rate showed changes with gestational age, ranging from 110 ± 14 bpm at the 6.0th week to 150 ± 12 bpm at the 14.0th week. Conclusions: transvaginal pulsed color Doppler equipment enabled cardiovascular evaluation in early pregnancy, being a noninvasive method and innocuous to the embryo. These values would be useful in new studies on dopplervelocimetry in this period of pregnancy.
Views64This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisAssessment of Embryo Heart Rate in Early Pregnancy by Transvaginal Ultrasonography with Color and Pulsed Doppler
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(9):551-555
07-23-2000DOI 10.1590/S0100-72032000000900003
Views64See morePurpose: to evaluate the evolution in the embryo heart rate in the first trimester of pregnancy. Patients and Methods: in a prospective study 206 pregnant women were evaluated in the first trimester of pregnancy, by transvaginal color Doppler sonography, using Aloka, SSD-2000 apparatus, with a 5-MHz transvaginal transducer. All examinations were performed by the same examiner, with the determination of embryo heart rate. The patients were classified into groups according to the gestational age, in half-week intervals from the 5th week of pregnancy on. Pregnancy outcome was evaluated by ultrasonography at the end of second and third trimesters. Mean and standard deviation were determined for each evaluated gestational age. Results: it was possible to determine normal values for embryo heart rate. Mean embryo heart rate showed changes with gestational age, ranging from 110 ± 14 bpm at the 6.0th week to 150 ± 12 bpm at the 14.0th week. Conclusions: transvaginal pulsed color Doppler equipment enabled cardiovascular evaluation in early pregnancy, being a noninvasive method and innocuous to the embryo. These values would be useful in new studies on dopplervelocimetry in this period of pregnancy.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Omphalocele: Fetal Prognosis in 51 Cases with Prenatal Diagnosis
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(1):31-37
06-27-2001
Summary
Trabalhos OriginaisOmphalocele: Fetal Prognosis in 51 Cases with Prenatal Diagnosis
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(1):31-37
06-27-2001DOI 10.1590/S0100-72032001000100005
Views52See morePurpose: to evaluate the prognosis of fetal omphalocele after prenatal diagnosis. Methods: fifty-one cases with prenatal diagnosis of fetal omphalocele were divided into three groups: group 1, isolated omphalocele; group 2, omphalocele associated with structural abnormalities and normal karyotype; group 3, omphalocele with abnormal karyotype. The data were analyzed for overall survival rate and postsurgery survival, considering associated malformations, gestational age at delivery, birth weight and size of omphalocele. Results: group 1 corresponded to 21% (n = 11), group 2, 55% (n = 28) and group 3,24% (n = 12). All of Group 3 died, and trisomy 18 was the most frequent chromosomal abnormality. The survival rate was 80% for group 1 and 25% for group 2. Sixteen cases underwent surgery (10 isolated and 6 associated), 81% survived (8 isolated and 5 associated). The median birth weight was 3,140 g and 2,000 g for survivals and non-survivals after surgery, respectively (p = 0.148), and the corresponding gestational age at delivery was 37 and 36 weeks (p = 0.836). The ratio of omphalocele/abdominal circumference decreased with gestation, 0.88 between 25-29 weeks and 0.65 between 30-35 weeks (p = 0.043). The size of omphalocele was not significantly different between the 3 groups (p = 0.988), and it was not associated to postsurgery prognosis (p = 0.553). Conclusion: the overall and postsurgery survival rates were 25 and 81%, respectively. Associated malformations were the main prognostic factor in prenatally diagnosed omphaloceles, since they are associated with prematurity and low birth weight.
Views52This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisOmphalocele: Fetal Prognosis in 51 Cases with Prenatal Diagnosis
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(1):31-37
06-27-2001DOI 10.1590/S0100-72032001000100005
Views52See morePurpose: to evaluate the prognosis of fetal omphalocele after prenatal diagnosis. Methods: fifty-one cases with prenatal diagnosis of fetal omphalocele were divided into three groups: group 1, isolated omphalocele; group 2, omphalocele associated with structural abnormalities and normal karyotype; group 3, omphalocele with abnormal karyotype. The data were analyzed for overall survival rate and postsurgery survival, considering associated malformations, gestational age at delivery, birth weight and size of omphalocele. Results: group 1 corresponded to 21% (n = 11), group 2, 55% (n = 28) and group 3,24% (n = 12). All of Group 3 died, and trisomy 18 was the most frequent chromosomal abnormality. The survival rate was 80% for group 1 and 25% for group 2. Sixteen cases underwent surgery (10 isolated and 6 associated), 81% survived (8 isolated and 5 associated). The median birth weight was 3,140 g and 2,000 g for survivals and non-survivals after surgery, respectively (p = 0.148), and the corresponding gestational age at delivery was 37 and 36 weeks (p = 0.836). The ratio of omphalocele/abdominal circumference decreased with gestation, 0.88 between 25-29 weeks and 0.65 between 30-35 weeks (p = 0.043). The size of omphalocele was not significantly different between the 3 groups (p = 0.988), and it was not associated to postsurgery prognosis (p = 0.553). Conclusion: the overall and postsurgery survival rates were 25 and 81%, respectively. Associated malformations were the main prognostic factor in prenatally diagnosed omphaloceles, since they are associated with prematurity and low birth weight.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Ultrasonographic evaluation of fetal hydrocephalus: association with perinatal mortality
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(6):383-390
06-27-2001
Summary
Trabalhos OriginaisUltrasonographic evaluation of fetal hydrocephalus: association with perinatal mortality
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(6):383-390
06-27-2001DOI 10.1590/S0100-72032001000600007
Views100See morePurpose: to evaluate the ultrasonographic parameters associated with perinatal mortality increase in cases of fetal hydrocephalus. Method: 45 cases of fetal hydrocephalus were followed-up between January 1996 and December 1999. Fetal hydrocephalus was diagnosed when the ratio of lateral ventricles and the corresponding cerebral hemispheres was above 0.35 or when the measurement of the atrium of the lateral ventricles was above 10 mm. In all examinations the type of hydrocephalus, severity, symmetry, evolution and time of diagnosis were defined. The patients were submitted to morphologic ultrasound in the search of other anatomical abnormalities. The amniotic fluid index and fetal deaths were registered. The main ultrasonographic findings were correlated with perinatal mortality. For statistical analysis, chi² test and exact Fisher test were used. The value of p<0,05 was considered to be significant. Results: a total of 20 deaths were observed (44.4%), 6 occurred intra-uterus and 14 in the neonatal period. The diagnosis of hydrocephalus was established at a mean gestational age of 29 weeks. There was no association between perinatal mortality and alterations in the amniotic fluid volume, time of diagnosis, symmetry and type of hydrocephalus and the presence of other intra- or extracranial anomalies. On the other hand, the severity of the disease was associated significantly with perinatal death (p<0.0001). Conclusion: among all the analyzed ultrasonographic parameters, only the severity of hydrocephalus presented statistical association with perinatal death.
Views100This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisUltrasonographic evaluation of fetal hydrocephalus: association with perinatal mortality
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(6):383-390
06-27-2001DOI 10.1590/S0100-72032001000600007
Views100See morePurpose: to evaluate the ultrasonographic parameters associated with perinatal mortality increase in cases of fetal hydrocephalus. Method: 45 cases of fetal hydrocephalus were followed-up between January 1996 and December 1999. Fetal hydrocephalus was diagnosed when the ratio of lateral ventricles and the corresponding cerebral hemispheres was above 0.35 or when the measurement of the atrium of the lateral ventricles was above 10 mm. In all examinations the type of hydrocephalus, severity, symmetry, evolution and time of diagnosis were defined. The patients were submitted to morphologic ultrasound in the search of other anatomical abnormalities. The amniotic fluid index and fetal deaths were registered. The main ultrasonographic findings were correlated with perinatal mortality. For statistical analysis, chi² test and exact Fisher test were used. The value of p<0,05 was considered to be significant. Results: a total of 20 deaths were observed (44.4%), 6 occurred intra-uterus and 14 in the neonatal period. The diagnosis of hydrocephalus was established at a mean gestational age of 29 weeks. There was no association between perinatal mortality and alterations in the amniotic fluid volume, time of diagnosis, symmetry and type of hydrocephalus and the presence of other intra- or extracranial anomalies. On the other hand, the severity of the disease was associated significantly with perinatal death (p<0.0001). Conclusion: among all the analyzed ultrasonographic parameters, only the severity of hydrocephalus presented statistical association with perinatal death.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Trabalhos Originais
Ultrasonographic Evaluation of Uterine Volume Variations
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(3):175-179
06-26-2001
Summary
Trabalhos OriginaisUltrasonographic Evaluation of Uterine Volume Variations
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(3):175-179
06-26-2001DOI 10.1590/S0100-72032001000300007
Views70Purpose: to determine the accuracy of transabdominal ultrasound (TAUS) in revealing physiological and pathological changes in uterine volume, and to compare uterine volume detected by TAUS and by transvaginal ultrasound (TVUS) in an attempt to determine the relationship between the two methods. Methods: a total of 1,186 pelvic echographic examinations (TAUS and TVUS) were first reviewed retrospectively in terms of the major diseases and indications for the examinations. A total of 480 TAUS examinations without uterine disease were then selected and uterine volume was correlated with age and parity. Finally, a retrospective study was conducted to compare the uterine volume of 50 women obtained by TAUS and TVUS. Data were analyzed statistically by Student's t-test and Spearman and Pearson correlation. Results: correlating with parity, volume was 44.4 cm³ for P = 0 (n = 99), 58.5 cm³ for P = 1 (n = 72), 75.8 cm³ for P = 2-3 (n = 137), 88cm³ for P = 4-5 (n = 56), and 105cm³ for P = 6 or more (n = 26), showing a positive correlation between parity and uterine volume. Calculation of Spearman's correlation coefficient yielded r = 0.59 and p = 0.001 and calculation of Pearson's correlation coefficient yielded r = 0.55 and the same p value. There were no significant differences between the uterine volumes detected by TAUS and TVUS. Conclusions: the volume increases with parity and changes with age, and these modifications are detected by TAUS. The two methods (TAUS and TVUS) are equivalent in determining the uterine volume; however, when TAUS is used, bladder filling allows a better evaluation of the uterine length.
Key-words UltrasonographyUterine volumeSee moreViews70This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Trabalhos OriginaisUltrasonographic Evaluation of Uterine Volume Variations
Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(3):175-179
06-26-2001DOI 10.1590/S0100-72032001000300007
Views70Purpose: to determine the accuracy of transabdominal ultrasound (TAUS) in revealing physiological and pathological changes in uterine volume, and to compare uterine volume detected by TAUS and by transvaginal ultrasound (TVUS) in an attempt to determine the relationship between the two methods. Methods: a total of 1,186 pelvic echographic examinations (TAUS and TVUS) were first reviewed retrospectively in terms of the major diseases and indications for the examinations. A total of 480 TAUS examinations without uterine disease were then selected and uterine volume was correlated with age and parity. Finally, a retrospective study was conducted to compare the uterine volume of 50 women obtained by TAUS and TVUS. Data were analyzed statistically by Student's t-test and Spearman and Pearson correlation. Results: correlating with parity, volume was 44.4 cm³ for P = 0 (n = 99), 58.5 cm³ for P = 1 (n = 72), 75.8 cm³ for P = 2-3 (n = 137), 88cm³ for P = 4-5 (n = 56), and 105cm³ for P = 6 or more (n = 26), showing a positive correlation between parity and uterine volume. Calculation of Spearman's correlation coefficient yielded r = 0.59 and p = 0.001 and calculation of Pearson's correlation coefficient yielded r = 0.55 and the same p value. There were no significant differences between the uterine volumes detected by TAUS and TVUS. Conclusions: the volume increases with parity and changes with age, and these modifications are detected by TAUS. The two methods (TAUS and TVUS) are equivalent in determining the uterine volume; however, when TAUS is used, bladder filling allows a better evaluation of the uterine length.
Key-words UltrasonographyUterine volumeSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Ultrasonography Archives - Revista Brasileira de Ginecologia e Obstetrícia
