Rubella Archives - Revista Brasileira de Ginecologia e Obstetrícia
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(2):66-70
DOI 10.1590/S0100-72032013000200005
PURPOSE: To ascertain the seroprevalence of human immunodeficiency virus (HIV), hepatitis B (HBV), toxoplasmosis and rubella infections in pregnant women in northwestern Paraná. METHODS: We conducted a retrospective study based on the results of serological screening during prenatal care of 1,534 patients during the first half of 2010. We included only results from the first prenatal exam and with a simultaneous search for IgG and IgM antibodies to rubella and toxoplasmosis. Serology was performed by microparticle enzyme immunoassay (MEIA). Data were analyzed statistically by the χ² test, with the level of significance set at 5%. RESULTS: HIV positivity was 0.3%, positivity of HBV serology (HbsAg) was 0.5%, reactivity to IgM antibodies to Toxoplasma gondii was 1.1%, and reactivity to IgG antibodies was 59.0%. For rubella, no patient was positive for IgM, and IgG reactivity was 99.6%. Data analysis showed no statistical association between seroprevalence and patient age, except for the frequency of anti-T. gondii IgG, which was higher in the 30 to 44 year age group. CONCLUSION: The prevalence of these infectious diseases in pregnant women from northwestern Paraná is comparable to that observed in other regions of Brazil.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2013;35(2):66-70
DOI 10.1590/S0100-72032013000200005
PURPOSE: To ascertain the seroprevalence of human immunodeficiency virus (HIV), hepatitis B (HBV), toxoplasmosis and rubella infections in pregnant women in northwestern Paraná. METHODS: We conducted a retrospective study based on the results of serological screening during prenatal care of 1,534 patients during the first half of 2010. We included only results from the first prenatal exam and with a simultaneous search for IgG and IgM antibodies to rubella and toxoplasmosis. Serology was performed by microparticle enzyme immunoassay (MEIA). Data were analyzed statistically by the χ² test, with the level of significance set at 5%. RESULTS: HIV positivity was 0.3%, positivity of HBV serology (HbsAg) was 0.5%, reactivity to IgM antibodies to Toxoplasma gondii was 1.1%, and reactivity to IgG antibodies was 59.0%. For rubella, no patient was positive for IgM, and IgG reactivity was 99.6%. Data analysis showed no statistical association between seroprevalence and patient age, except for the frequency of anti-T. gondii IgG, which was higher in the 30 to 44 year age group. CONCLUSION: The prevalence of these infectious diseases in pregnant women from northwestern Paraná is comparable to that observed in other regions of Brazil.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(5):261-266
DOI 10.1590/S0100-72031999000500003
Purpose: to evaluate the immune status of women in reproductive age regarding the rubella virus. Methods: 2,243 samples of serum from women in the age range of 15 to 45 years, with an average of 26 years, living in the urban area of Natal, RN were analyzed, to evaluate the immune status in regard to rubella virus. Of these women, 1,170 (52.1%) were pregnant and 1,073 (47.9%) were not. IgM and IgG antibodies were determined, using solid phase ELISA and fluorescence (ELFA) techniques. Results: of the 2,243 women, 1,632 showed immunity to rubella virus and 611 did not, therefore being susceptible to this virus. The rates of immunity and susceptibility in this study were 73.0% and 27.0%, respectively. In 611 susceptible woman, 14.5% did not present antibodies against rubella virus, 7.7% had only IgM antibody and 4.8% had IgG and IgM antibodies. Conclusions: our findings show that a significant group of women from Natal, in reproductive age, is still susceptible to rubella virus, indicating the risk of congenital infection by this pathogen. We advise the selective vaccination of those women against rubella to prevent clinical manifestations related to the congenital form of the disease.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(5):261-266
DOI 10.1590/S0100-72031999000500003
Purpose: to evaluate the immune status of women in reproductive age regarding the rubella virus. Methods: 2,243 samples of serum from women in the age range of 15 to 45 years, with an average of 26 years, living in the urban area of Natal, RN were analyzed, to evaluate the immune status in regard to rubella virus. Of these women, 1,170 (52.1%) were pregnant and 1,073 (47.9%) were not. IgM and IgG antibodies were determined, using solid phase ELISA and fluorescence (ELFA) techniques. Results: of the 2,243 women, 1,632 showed immunity to rubella virus and 611 did not, therefore being susceptible to this virus. The rates of immunity and susceptibility in this study were 73.0% and 27.0%, respectively. In 611 susceptible woman, 14.5% did not present antibodies against rubella virus, 7.7% had only IgM antibody and 4.8% had IgG and IgM antibodies. Conclusions: our findings show that a significant group of women from Natal, in reproductive age, is still susceptible to rubella virus, indicating the risk of congenital infection by this pathogen. We advise the selective vaccination of those women against rubella to prevent clinical manifestations related to the congenital form of the disease.