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Review Article
Tribulus Terrestris for Female Sexual Dysfunction: A Systematic Review
- Ana Luiza Cabrera Martimbianco
, - Rafael Leite Pacheco ,
- Fábia Lima Vilarino ,
- Carolina de Oliveira Cruz Latorraca ,
- Maria Regina Torloni , [ ... ],
- Rachel Riera
08-26-2020
Summary
Review ArticleTribulus Terrestris for Female Sexual Dysfunction: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(7):427-435
08-26-2020- Ana Luiza Cabrera Martimbianco ,
- Rafael Leite Pacheco ,
- Fábia Lima Vilarino ,
- Carolina de Oliveira Cruz Latorraca ,
- Maria Regina Torloni ,
- Rachel Riera
Views248See moreAbstract
Objective
We performed a systematic review to assess the effectiveness and safety of Tribulus terrestris to treat female sexual dysfunction (FSD).
Data sources
We performed unrestricted electronic searches in the MEDLINE, CENTRAL, EMBASE, LILACS, CINAHL, PsycINFO,WHO-ICTR, Clinicaltrials.gov and OpenGrey databases. Selection of studies We included any randomized controlled trials (RCTs) that compared T. terrestris versus inactive/active interventions. After the selection process, conducted by two reviewers, 5 RCTs (n = 279 participants) were included.
Data collection
Data extraction was performed by two reviewers with a preestablished data collection formulary.
Data synthesis
Due to lack of data and clinical heterogeneity, we could not perform meta-analyses. The risk of bias was assessed by the Cochrane Risk of Bias (RoB) tool, and the certainty of evidence was assessed with Grading of Recommendations, Assessment, Development and Evaluations (GRADE).
Results
After 1 to 3 months of treatment, premenopausal and postmenopausal women randomized to T. terrestris had a significant increase in sexual function scores. Three months of treatment with T. terrestris showed a significant increase in the serum testosterone levels of premenopausal women. There was no report of serious adverse events, and none of the studies assessed health-related quality of life. The certainty of the evidence was very low, whichmeans that we have very little confidence in the effect estimates, and future studies are likely to change these estimates.
Conclusion
MoreRCTs are needed to supportor refute the use of T. terrestris. The decision to use this intervention should be shared with the patients, and the uncertainties around its effects should be discussed in the clinical decision-making process. Number of Protocol registration in PROSPERO database: CRD42019121130
Views248
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleTribulus Terrestris for Female Sexual Dysfunction: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(7):427-435
08-26-2020- Ana Luiza Cabrera Martimbianco ,
- Rafael Leite Pacheco ,
- Fábia Lima Vilarino ,
- Carolina de Oliveira Cruz Latorraca ,
- Maria Regina Torloni ,
- Rachel Riera
Views248See moreAbstract
Objective
We performed a systematic review to assess the effectiveness and safety of Tribulus terrestris to treat female sexual dysfunction (FSD).
Data sources
We performed unrestricted electronic searches in the MEDLINE, CENTRAL, EMBASE, LILACS, CINAHL, PsycINFO,WHO-ICTR, Clinicaltrials.gov and OpenGrey databases. Selection of studies We included any randomized controlled trials (RCTs) that compared T. terrestris versus inactive/active interventions. After the selection process, conducted by two reviewers, 5 RCTs (n = 279 participants) were included.
Data collection
Data extraction was performed by two reviewers with a preestablished data collection formulary.
Data synthesis
Due to lack of data and clinical heterogeneity, we could not perform meta-analyses. The risk of bias was assessed by the Cochrane Risk of Bias (RoB) tool, and the certainty of evidence was assessed with Grading of Recommendations, Assessment, Development and Evaluations (GRADE).
Results
After 1 to 3 months of treatment, premenopausal and postmenopausal women randomized to T. terrestris had a significant increase in sexual function scores. Three months of treatment with T. terrestris showed a significant increase in the serum testosterone levels of premenopausal women. There was no report of serious adverse events, and none of the studies assessed health-related quality of life. The certainty of the evidence was very low, whichmeans that we have very little confidence in the effect estimates, and future studies are likely to change these estimates.
Conclusion
MoreRCTs are needed to supportor refute the use of T. terrestris. The decision to use this intervention should be shared with the patients, and the uncertainties around its effects should be discussed in the clinical decision-making process. Number of Protocol registration in PROSPERO database: CRD42019121130
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Ana Luiza Cabrera Martimbianco
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Review Article
Quality of Life in Women with Defecatory Dysfunctions: Systematic Review of Questionnaires Validated in the Portuguese Language
- José Ananias Vasconcelos Neto ,
- Camila Teixeira Moreira Vasconcelos,
- Sara Arcanjo Lino Karbage,
- Hérdeny Di Cárlly de Almeida Rocha Farias,
- Stéffany Gadelha de Macêdo Machado, [ ... ],
- Dayana Maia Saboia
03-01-2019
Summary
Review ArticleQuality of Life in Women with Defecatory Dysfunctions: Systematic Review of Questionnaires Validated in the Portuguese Language
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(3):191-198
03-01-2019- José Ananias Vasconcelos Neto ,
- Camila Teixeira Moreira Vasconcelos,
- Sara Arcanjo Lino Karbage,
- Hérdeny Di Cárlly de Almeida Rocha Farias,
- Stéffany Gadelha de Macêdo Machado,
- Dayana Maia Saboia
Views189See moreAbstract
Objective
To identify the quality of life (QoL) assessment instruments related to the health of women with fecal incontinence (FI) or anal incontinence (AI).
Data Sources
Systematic review conducted in the Virtual Health Library (VHL), PubMed and Cochrane Library databases. The descriptors used were: Questionnaire, Questionnaires, Quality of life, validation, validation Studies, anal incontinence, fecal incontinence and constipation. The search was performed between December 26, 2017 and the beginning of January 2018. The limits used were female gender.
Selection of Studies
Initially, 5,143 articles were obtained in the search. The articles of validation for Portuguese of questionnaires for the evaluation of the impact of FI/AI on the QoL of women were considered eligible.
Data Collection
The article search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guidelines.
Data Synthesis
Of the 5,143 articles, only 2 fulfilled the inclusion and exclusion criteria: Fecal Incontinence Quality of Life (FIQL) and the Wexner scale (WS). The FIQL evaluates the QoL related to FI, not covering flatus incontinence. The WS assesses flatus incontinence and the severity of the AI. The WS obtained an interclass correlation coefficient (ICC) of 0.932 and a Cronbach α coefficient > 0.90. The FIQL obtained intraexaminer and interexaminer reproducibility ranging from 0.929 to 0.957 and from 0.944 to 0.969, respectively.
Conclusions
The WS and the FIQL have satisfactory reliability and validity for use during gynecological consultations.
Views189This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleQuality of Life in Women with Defecatory Dysfunctions: Systematic Review of Questionnaires Validated in the Portuguese Language
Revista Brasileira de Ginecologia e Obstetrícia. 2019;41(3):191-198
03-01-2019- José Ananias Vasconcelos Neto ,
- Camila Teixeira Moreira Vasconcelos,
- Sara Arcanjo Lino Karbage,
- Hérdeny Di Cárlly de Almeida Rocha Farias,
- Stéffany Gadelha de Macêdo Machado,
- Dayana Maia Saboia
Views189See moreAbstract
Objective
To identify the quality of life (QoL) assessment instruments related to the health of women with fecal incontinence (FI) or anal incontinence (AI).
Data Sources
Systematic review conducted in the Virtual Health Library (VHL), PubMed and Cochrane Library databases. The descriptors used were: Questionnaire, Questionnaires, Quality of life, validation, validation Studies, anal incontinence, fecal incontinence and constipation. The search was performed between December 26, 2017 and the beginning of January 2018. The limits used were female gender.
Selection of Studies
Initially, 5,143 articles were obtained in the search. The articles of validation for Portuguese of questionnaires for the evaluation of the impact of FI/AI on the QoL of women were considered eligible.
Data Collection
The article search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guidelines.
Data Synthesis
Of the 5,143 articles, only 2 fulfilled the inclusion and exclusion criteria: Fecal Incontinence Quality of Life (FIQL) and the Wexner scale (WS). The FIQL evaluates the QoL related to FI, not covering flatus incontinence. The WS assesses flatus incontinence and the severity of the AI. The WS obtained an interclass correlation coefficient (ICC) of 0.932 and a Cronbach α coefficient > 0.90. The FIQL obtained intraexaminer and interexaminer reproducibility ranging from 0.929 to 0.957 and from 0.944 to 0.969, respectively.
Conclusions
The WS and the FIQL have satisfactory reliability and validity for use during gynecological consultations.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - José Ananias Vasconcelos Neto
review Archives - Revista Brasileira de Ginecologia e Obstetrícia
