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Review Article
Non-RhD alloimmunization in pregnancy: an updated review
- Sabrina Menes Ares
, - Luciano Marcondes Machado Nardozza ,
- Edward Araujo Júnior ,
- Eduardo Félix Martins Santana
00-00-2024
Summary
Review ArticleNon-RhD alloimmunization in pregnancy: an updated review
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo22
00-00-2024- Sabrina Menes Ares ,
- Luciano Marcondes Machado Nardozza ,
- Edward Araujo Júnior ,
- Eduardo Félix Martins Santana
Views434Abstract
RhD alloimmunization in pregnancy is still the main cause of hemolytic disease of the fetus and neonate (HDFN). Nevertheless, there are other antigens that may be associated with the occurrence of this phenomenon and that have been growing in proportion, given that current prevention strategies focus only on anti-RhD antibodies. Although not widespread, the screening and diagnostic management of the disease caused by these antibodies has recommendations in the literature. For this reason, the following review was carried out with the objective of listing the main red blood cell antigen groups described — such as Rh, ABO, Kell, MNS, Duffy, Kidd, among others — addressing the clinical importance of each one, prevalence in different countries, and recommended management when detecting such antibodies during pregnancy.
Key-words Blood group antigensErythroblastosisfetalFetal diseasesNon-Rh alloimmunizationPregnancyPrevalenceRh isoimmunizationSee moreViews434
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleNon-RhD alloimmunization in pregnancy: an updated review
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo22
00-00-2024- Sabrina Menes Ares ,
- Luciano Marcondes Machado Nardozza ,
- Edward Araujo Júnior ,
- Eduardo Félix Martins Santana
Views434Abstract
RhD alloimmunization in pregnancy is still the main cause of hemolytic disease of the fetus and neonate (HDFN). Nevertheless, there are other antigens that may be associated with the occurrence of this phenomenon and that have been growing in proportion, given that current prevention strategies focus only on anti-RhD antibodies. Although not widespread, the screening and diagnostic management of the disease caused by these antibodies has recommendations in the literature. For this reason, the following review was carried out with the objective of listing the main red blood cell antigen groups described — such as Rh, ABO, Kell, MNS, Duffy, Kidd, among others — addressing the clinical importance of each one, prevalence in different countries, and recommended management when detecting such antibodies during pregnancy.
Key-words Blood group antigensErythroblastosisfetalFetal diseasesNon-Rh alloimmunizationPregnancyPrevalenceRh isoimmunizationSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Sabrina Menes Ares
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Original Article
Obstetric and Perinatal Outcomes in Pregnant Women with Lupus: Retrospective Study in a Portuguese Tertiary Center
- InêsFerreira Jorge ,
- JoanaMourão Vieitez Frade ,
- SusanaPaula Leonardo Dias Abreu Capela ,
- AndréLaboreiro Ferreira Mendes da Graça ,
- MariaLuísa Aleixo Gomes Pinto Grilo , [ ... ],
- AnaMónica Miguel Mendonça de Castro Centeno
12-11-2023
Summary
Original ArticleObstetric and Perinatal Outcomes in Pregnant Women with Lupus: Retrospective Study in a Portuguese Tertiary Center
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(10):568-574
12-11-2023- InêsFerreira Jorge ,
- JoanaMourão Vieitez Frade ,
- SusanaPaula Leonardo Dias Abreu Capela ,
- AndréLaboreiro Ferreira Mendes da Graça ,
- MariaLuísa Aleixo Gomes Pinto Grilo ,
- AnaMónica Miguel Mendonça de Castro Centeno
Views170See moreAbstract
Objective
Pregnancy in women with lupus poses a higher risk of complications compared with the general population. The present study aimed to determine and describe the obstetric and neonatal outcomes of pregnant women with lupus.
Materials and Methods
We conducted an observational retrospective study of pregnant women with the diagnosis of lupus, who were selected and followed at the Maternal-Fetal Medicine Clinic of our institution between January 2013 and July 2018. We analyzed 59 pregnancies and 52 newborns, and collected data regarding sociodemographic features, the preconception period, pregnancy, childbirth, postpartum and the newborn. A descriptive analysis of the variables was performed.
Results
In 58% of the cases, the pregnancy was uneventful. We registered flares in 25% of the cases, preeclampsia in 3%, fetal growth restriction in 12%, gestational loss in 10%, preterm labor in 10%, postpartum complications in 20%, and small for gestational age newborns in 17% of the cases.
Conclusions
Most pregnancies in women with lupus have favorable obstetric and neonatal outcomes. Prenatal counseling, adequate multidisciplinary surveillance, and optimized treatment of the disease are fundamental pillars for these good results.
Views170This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleObstetric and Perinatal Outcomes in Pregnant Women with Lupus: Retrospective Study in a Portuguese Tertiary Center
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(10):568-574
12-11-2023- InêsFerreira Jorge ,
- JoanaMourão Vieitez Frade ,
- SusanaPaula Leonardo Dias Abreu Capela ,
- AndréLaboreiro Ferreira Mendes da Graça ,
- MariaLuísa Aleixo Gomes Pinto Grilo ,
- AnaMónica Miguel Mendonça de Castro Centeno
Views170See moreAbstract
Objective
Pregnancy in women with lupus poses a higher risk of complications compared with the general population. The present study aimed to determine and describe the obstetric and neonatal outcomes of pregnant women with lupus.
Materials and Methods
We conducted an observational retrospective study of pregnant women with the diagnosis of lupus, who were selected and followed at the Maternal-Fetal Medicine Clinic of our institution between January 2013 and July 2018. We analyzed 59 pregnancies and 52 newborns, and collected data regarding sociodemographic features, the preconception period, pregnancy, childbirth, postpartum and the newborn. A descriptive analysis of the variables was performed.
Results
In 58% of the cases, the pregnancy was uneventful. We registered flares in 25% of the cases, preeclampsia in 3%, fetal growth restriction in 12%, gestational loss in 10%, preterm labor in 10%, postpartum complications in 20%, and small for gestational age newborns in 17% of the cases.
Conclusions
Most pregnancies in women with lupus have favorable obstetric and neonatal outcomes. Prenatal counseling, adequate multidisciplinary surveillance, and optimized treatment of the disease are fundamental pillars for these good results.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- InêsFerreira Jorge
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Original Article
Thyroid Volume in Pregnancy is Associated with Parity, Gestational Age, and Body Mass Index in an Iodine-sufficient Area
- Mariana Couto Monteiro ,
- Gabriela Assayag ,
- Ricardo Botler ,
- Anice Bergamin ,
- Flávia Lúcia Conceição , [ ... ],
- Patrícia Fátima Santos Teixeira
12-11-2023
Summary
Original ArticleThyroid Volume in Pregnancy is Associated with Parity, Gestational Age, and Body Mass Index in an Iodine-sufficient Area
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(10):557-561
12-11-2023- Mariana Couto Monteiro ,
- Gabriela Assayag ,
- Ricardo Botler ,
- Anice Bergamin ,
- Flávia Lúcia Conceição ,
- Nathalie Silva de Morais ,
- Roberto Perrota de Seixas ,
- Tatiana Martins Benvenuto Louro Berbara ,
- Annie Schtscherbyna ,
- Carolina Martins Corcino ,
- Débora Ayres Saraiva ,
- Mário Vaisman ,
- Patrícia Fátima Santos Teixeira
Views97See moreAbstract
Objective
We compared thyroid volume (TV) and presence of nodular goiter (NG) in pregnant vs. non-pregnant women in an iodine-sufficient area. We also evaluated the relationship between gestational age, parity, and TV in the pregnant women group, and determined the 2.5th and 97.5th percentiles of normal TV in pregnancy.
Methods
This cross-sectional study included 299 healthy women (216 pregnant) without previous thyroid diseases. Thyroid ultrasounds were performed and compared between pregnant and non-pregnant women. The range of normal distribution of TV (2.5th and 97.5th percentiles) in pregnancy was determined after excluding individuals with positive thyroid antibodies, NG, and/or abnormal serum thyrotropin (TSH) or free thyroxine (FT4).
Results
Thyroid volume was larger among pregnant compared to non-pregnant women (8.6 vs 6.1 cm3; p< 0.001) and was positively correlated with gestational age (rs = 0.221; p = 0.001), body mass index (BMI, rs 0.165; p = 0.002), and FT4 levels (rs 0.118 p = 0.021). Nodular goiter frequency did not differ between the two groups. There was a negative correlation between TV and TSH (rs -0.13; p = 0.014). Thyroid volume was lower among primiparous compared to multiparous patients (7.8 vs 8.9; p< 0.001) and was positively correlated with parity (rs 0.161; p = 0.016). The 2.5th and 97.5th percentiles of TV were 4.23 and 16.47 cm3, respectively.
Conclusion
Thyroid volume was higher in pregnant compared to non-pregnant women and was positively related to parity, BMI, and gestational age in a normal iodine status population. Pregnancy did not interfere with the development of NG.
Views97This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleThyroid Volume in Pregnancy is Associated with Parity, Gestational Age, and Body Mass Index in an Iodine-sufficient Area
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(10):557-561
12-11-2023- Mariana Couto Monteiro ,
- Gabriela Assayag ,
- Ricardo Botler ,
- Anice Bergamin ,
- Flávia Lúcia Conceição ,
- Nathalie Silva de Morais ,
- Roberto Perrota de Seixas ,
- Tatiana Martins Benvenuto Louro Berbara ,
- Annie Schtscherbyna ,
- Carolina Martins Corcino ,
- Débora Ayres Saraiva ,
- Mário Vaisman ,
- Patrícia Fátima Santos Teixeira
Views97See moreAbstract
Objective
We compared thyroid volume (TV) and presence of nodular goiter (NG) in pregnant vs. non-pregnant women in an iodine-sufficient area. We also evaluated the relationship between gestational age, parity, and TV in the pregnant women group, and determined the 2.5th and 97.5th percentiles of normal TV in pregnancy.
Methods
This cross-sectional study included 299 healthy women (216 pregnant) without previous thyroid diseases. Thyroid ultrasounds were performed and compared between pregnant and non-pregnant women. The range of normal distribution of TV (2.5th and 97.5th percentiles) in pregnancy was determined after excluding individuals with positive thyroid antibodies, NG, and/or abnormal serum thyrotropin (TSH) or free thyroxine (FT4).
Results
Thyroid volume was larger among pregnant compared to non-pregnant women (8.6 vs 6.1 cm3; p< 0.001) and was positively correlated with gestational age (rs = 0.221; p = 0.001), body mass index (BMI, rs 0.165; p = 0.002), and FT4 levels (rs 0.118 p = 0.021). Nodular goiter frequency did not differ between the two groups. There was a negative correlation between TV and TSH (rs -0.13; p = 0.014). Thyroid volume was lower among primiparous compared to multiparous patients (7.8 vs 8.9; p< 0.001) and was positively correlated with parity (rs 0.161; p = 0.016). The 2.5th and 97.5th percentiles of TV were 4.23 and 16.47 cm3, respectively.
Conclusion
Thyroid volume was higher in pregnant compared to non-pregnant women and was positively related to parity, BMI, and gestational age in a normal iodine status population. Pregnancy did not interfere with the development of NG.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Mariana Couto Monteiro
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Original Article/Obstetrics
Factors Related to Low COVID-19 Vaccination Rate in Pregnant and Postpartum Women with and without COVID-19
- Dilek Menekse Beser ,
- Derya Uyan Hendem ,
- Deniz Oluklu ,
- Ezgi Turgut ,
- Necati Hancerliogullari , [ ... ],
- Dilek Sahin
12-05-2023
Summary
Original Article/ObstetricsFactors Related to Low COVID-19 Vaccination Rate in Pregnant and Postpartum Women with and without COVID-19
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(11):638-645
12-05-2023- Dilek Menekse Beser ,
- Derya Uyan Hendem ,
- Deniz Oluklu ,
- Ezgi Turgut ,
- Necati Hancerliogullari ,
- Sule Goncu Ayhan ,
- Ozlem Moraloglu Tekin ,
- Dilek Sahin
Views122See moreAbstract
Objective
This study focused on pregnant and postpartum women during the COVID-19 pandemic, aiming to determine the attitudes and behaviors of vaccinated and unvaccinated groups, and the vaccination behaviors in the groups with and without the disease. The reasons for refusing the vaccine were also questioned.
Methods
This cross-sectional study was performed from September 2021 to October 2021. The study data were collected using a face-to-face questionnaire. The participants were pregnant women who applied to the hospital for routine antenatal care and were hospitalized, and women in the postpartum period. Additionally, pregnant and postpartum patients who were diagnosed with COVID-19 at the time of admission and were hospitalized and admitted to the intensive care unit due to this disease were also included in the study.
Results
A total of 1,146 pregnant and postpartum women who completed the questionnaire were included in our study. Only 43 (3.8%) of the participants were vaccinated; 154 (13.4%) of the participants had comorbidities. The number of COVID-19-positive patients was 153. The lack of sufficient information about the safety of the COVID-19 vaccine is the most common reason for the refusal.
Conclusion
Vaccine refusal can significantly delay or hinder herd immunity, resulting in higher morbidity and mortality. Considering the adverse effects of COVID-19 on pregnancy, it is essential to understand pregnant and postpartum women's perceptions toward vaccination to end the pandemic.
Views122This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original Article/ObstetricsFactors Related to Low COVID-19 Vaccination Rate in Pregnant and Postpartum Women with and without COVID-19
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(11):638-645
12-05-2023- Dilek Menekse Beser ,
- Derya Uyan Hendem ,
- Deniz Oluklu ,
- Ezgi Turgut ,
- Necati Hancerliogullari ,
- Sule Goncu Ayhan ,
- Ozlem Moraloglu Tekin ,
- Dilek Sahin
Views122See moreAbstract
Objective
This study focused on pregnant and postpartum women during the COVID-19 pandemic, aiming to determine the attitudes and behaviors of vaccinated and unvaccinated groups, and the vaccination behaviors in the groups with and without the disease. The reasons for refusing the vaccine were also questioned.
Methods
This cross-sectional study was performed from September 2021 to October 2021. The study data were collected using a face-to-face questionnaire. The participants were pregnant women who applied to the hospital for routine antenatal care and were hospitalized, and women in the postpartum period. Additionally, pregnant and postpartum patients who were diagnosed with COVID-19 at the time of admission and were hospitalized and admitted to the intensive care unit due to this disease were also included in the study.
Results
A total of 1,146 pregnant and postpartum women who completed the questionnaire were included in our study. Only 43 (3.8%) of the participants were vaccinated; 154 (13.4%) of the participants had comorbidities. The number of COVID-19-positive patients was 153. The lack of sufficient information about the safety of the COVID-19 vaccine is the most common reason for the refusal.
Conclusion
Vaccine refusal can significantly delay or hinder herd immunity, resulting in higher morbidity and mortality. Considering the adverse effects of COVID-19 on pregnancy, it is essential to understand pregnant and postpartum women's perceptions toward vaccination to end the pandemic.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- Dilek Menekse Beser
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Original Article
Impact of Obesity and Hyperglycemia on Pregnancy-specific Urinary Incontinence
- Giovana Vesentini ,
- Fernanda Piculo ,
- Gabriela Marini ,
- Angélica Mércia Pascon Barbosa ,
- José Eduardo Corrente , [ ... ],
- Marilza Vieira Cunha Rudge
08-04-2023
Summary
Original ArticleImpact of Obesity and Hyperglycemia on Pregnancy-specific Urinary Incontinence
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(6):303-311
08-04-2023- Giovana Vesentini ,
- Fernanda Piculo ,
- Gabriela Marini ,
- Angélica Mércia Pascon Barbosa ,
- José Eduardo Corrente ,
- Marilza Vieira Cunha Rudge
Views123See moreAbstract
Objective
The lack of data on the impact of hyperglycemia and obesity on the prevalence of pregnancy-specific urinary incontinence (PSUI) led us to conduct a cross-sectional study on the prevalence and characteristics of PSUI using validated questionnaires and clinical data.
Methods
This cross-sectional study included 539 women with a gestational age of 34 weeks who visited a tertiary university hospital between 2015 and 2018. The main outcome measures were the prevalence of PSUI, the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF), and the Incontinence Severity Index (ISI) questionnaires. The women were classified into four groups: normoglycemic lean, normoglycemic obese, hyperglycemic lean, and hyperglycemic obese. The differences between groups were tested using descriptive statistics. Associations were estimated using logistic regression analysis and presented as unadjusted and adjusted odds ratios.
Results
Prevalence rates of PSUI were no different between groups. However, significant difference in hyperglycemic groups worse scores for severe and very severe PSUI. When adjusted data for confound factors was compared with normoglycemic lean group, the hyperglycemic obese group had significantly higher odds for severe and very severe forms of UI using ICIQ-SF (aOR 3.157; 95% CI 1.308 to 7.263) and ISI (aOR 20.324; 95% CI 2.265 to 182.329) questionnaires and highest perceived impact of PSUI (aOR 4.449; 95% CI 1.591 to 12.442).
Conclusion
Our data indicate that obesity and hyperglycemia during pregnancy significantly increase the odds of severe forms and perceived impact of PSUI. Therefore, further effective preventive and curative treatments are greatly needed.
Views123This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleImpact of Obesity and Hyperglycemia on Pregnancy-specific Urinary Incontinence
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(6):303-311
08-04-2023- Giovana Vesentini ,
- Fernanda Piculo ,
- Gabriela Marini ,
- Angélica Mércia Pascon Barbosa ,
- José Eduardo Corrente ,
- Marilza Vieira Cunha Rudge
Views123See moreAbstract
Objective
The lack of data on the impact of hyperglycemia and obesity on the prevalence of pregnancy-specific urinary incontinence (PSUI) led us to conduct a cross-sectional study on the prevalence and characteristics of PSUI using validated questionnaires and clinical data.
Methods
This cross-sectional study included 539 women with a gestational age of 34 weeks who visited a tertiary university hospital between 2015 and 2018. The main outcome measures were the prevalence of PSUI, the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF), and the Incontinence Severity Index (ISI) questionnaires. The women were classified into four groups: normoglycemic lean, normoglycemic obese, hyperglycemic lean, and hyperglycemic obese. The differences between groups were tested using descriptive statistics. Associations were estimated using logistic regression analysis and presented as unadjusted and adjusted odds ratios.
Results
Prevalence rates of PSUI were no different between groups. However, significant difference in hyperglycemic groups worse scores for severe and very severe PSUI. When adjusted data for confound factors was compared with normoglycemic lean group, the hyperglycemic obese group had significantly higher odds for severe and very severe forms of UI using ICIQ-SF (aOR 3.157; 95% CI 1.308 to 7.263) and ISI (aOR 20.324; 95% CI 2.265 to 182.329) questionnaires and highest perceived impact of PSUI (aOR 4.449; 95% CI 1.591 to 12.442).
Conclusion
Our data indicate that obesity and hyperglycemia during pregnancy significantly increase the odds of severe forms and perceived impact of PSUI. Therefore, further effective preventive and curative treatments are greatly needed.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Giovana Vesentini
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Original Article
Fertility Does not Quarantine: Coronavirus Disease 2019 Pandemic Impacts on in Vitro Fertilization Clinical Pregnancy Rates
- Fernanda de Almeida Vieira ,
- Ricardo Pasquini Neto ,
- Mariana Cristina Gomes Morila ,
- Jean Borges Curimbaba ,
- Daniela Sasso Pasquini , [ ... ],
- Jan Pawel Andrade Pachnicki
07-10-2023
Summary
Original ArticleFertility Does not Quarantine: Coronavirus Disease 2019 Pandemic Impacts on in Vitro Fertilization Clinical Pregnancy Rates
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(3):142-148
07-10-2023- Fernanda de Almeida Vieira ,
- Ricardo Pasquini Neto ,
- Mariana Cristina Gomes Morila ,
- Jean Borges Curimbaba ,
- Daniela Sasso Pasquini ,
- Paulo Cesar Zimmermann Felchner ,
- Gustavo Wandresen ,
- Jan Pawel Andrade Pachnicki
Views86See moreAbstract
Objective
To understand the impact of the coronavirus disease 2019 pandemic on in vitro fertilization (IVF) clinical pregnancy rates and analyze factors that may have influenced their outcome.
Methods
This was a retrospective observational study conducted at a tertiary-care Brazilian fertility center. All fresh IVF and embryo warming cycles performed from March 11 to December 31, 2018–2021 were analyzed, and their data were used to calculate fertilization, embryo cleavage, cycle cancellation, embryo transfer (ET), and clinical pregnancy rates. Statistical tests were used to evaluate the alterations found. Logistic regression models were used to explore the association of the categorical variables with the observed clinical pregnancy rates. Data from 2018 and 2019 (prepandemic) and 2020 and 2021 (pandemic) were grouped.
Results
A total of 756 cycles were analyzed (n = 360 prepandemic and n = 396 pandemic). The age group of the patients, fertilization rates, and cleavage rates did not have significant differences (p > 0.05). There was a reduction in the percentage of fresh IVF and an increase in embryo warming cycles (p = 0.005) during the pandemic. There was also an increase in fresh cycle cancellations (p < 0.001) and a reduction in ET rates (p < 0.001). The pandemic had a negative impact on clinical pregnancy rates (p < 0.001) especially due to the increase in fresh cycle cancellations (p < 0.001).
Conclusion
Embryo warming cycles with subsequent frozen-thawed ET were presented as a viable alternative to continue assisted reproductive treatments against pandemic restrictions on fresh cycles, ensuring clinical pregnancy, albeit at a lower rate than that of the prepandemic period.
Views86This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleFertility Does not Quarantine: Coronavirus Disease 2019 Pandemic Impacts on in Vitro Fertilization Clinical Pregnancy Rates
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(3):142-148
07-10-2023- Fernanda de Almeida Vieira ,
- Ricardo Pasquini Neto ,
- Mariana Cristina Gomes Morila ,
- Jean Borges Curimbaba ,
- Daniela Sasso Pasquini ,
- Paulo Cesar Zimmermann Felchner ,
- Gustavo Wandresen ,
- Jan Pawel Andrade Pachnicki
Views86See moreAbstract
Objective
To understand the impact of the coronavirus disease 2019 pandemic on in vitro fertilization (IVF) clinical pregnancy rates and analyze factors that may have influenced their outcome.
Methods
This was a retrospective observational study conducted at a tertiary-care Brazilian fertility center. All fresh IVF and embryo warming cycles performed from March 11 to December 31, 2018–2021 were analyzed, and their data were used to calculate fertilization, embryo cleavage, cycle cancellation, embryo transfer (ET), and clinical pregnancy rates. Statistical tests were used to evaluate the alterations found. Logistic regression models were used to explore the association of the categorical variables with the observed clinical pregnancy rates. Data from 2018 and 2019 (prepandemic) and 2020 and 2021 (pandemic) were grouped.
Results
A total of 756 cycles were analyzed (n = 360 prepandemic and n = 396 pandemic). The age group of the patients, fertilization rates, and cleavage rates did not have significant differences (p > 0.05). There was a reduction in the percentage of fresh IVF and an increase in embryo warming cycles (p = 0.005) during the pandemic. There was also an increase in fresh cycle cancellations (p < 0.001) and a reduction in ET rates (p < 0.001). The pandemic had a negative impact on clinical pregnancy rates (p < 0.001) especially due to the increase in fresh cycle cancellations (p < 0.001).
Conclusion
Embryo warming cycles with subsequent frozen-thawed ET were presented as a viable alternative to continue assisted reproductive treatments against pandemic restrictions on fresh cycles, ensuring clinical pregnancy, albeit at a lower rate than that of the prepandemic period.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- Fernanda de Almeida Vieira
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Review Article
Technologies Applied to the Mental Health Care of Pregnant Women: A Systematic Literature Review
- Laís Lage de Carvalho ,
- Júlia Magna da Silva Teixeira ,
- Roberto José Gervásio Unger ,
- Vivian Genaro Motti ,
- Giovanni Marcos Lovisi , [ ... ],
- Fabiane Rossi dos Santos Grincenkov
07-10-2023
Summary
Review ArticleTechnologies Applied to the Mental Health Care of Pregnant Women: A Systematic Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(3):149-159
07-10-2023- Laís Lage de Carvalho ,
- Júlia Magna da Silva Teixeira ,
- Roberto José Gervásio Unger ,
- Vivian Genaro Motti ,
- Giovanni Marcos Lovisi ,
- Fabiane Rossi dos Santos Grincenkov
Views180See moreAbstract
Objective:
This article aims to review the literature regarding the use of technologies to promote mental health for pregnant women. We seek to: understand the strategies that pregnant women use for mental health care. Also, we investigate the existence of scientific evidence that validates such practices.
Methods:
This study follows the PRISMA guidelines for systematic reviews. We analyze 27 studies published between 2012 and 2019. We include publications in Portuguese, English, and Spanish.
Results:
The results revealed several different possibilities to use technology, including the use of text messages and mobile applications on smartphones. Mobile applications are the most commonly used approaches (22.5%). Regarding the strategies used, cognitive-behavioral approaches, including mood checks, relaxation exercises, and psychoeducation comprised 44.12% of the content.
Conclusion:
There is a need for further investigation and research and development efforts in this field to better understand the possibilities of intervention in mental health in the digital age.
Views180This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleTechnologies Applied to the Mental Health Care of Pregnant Women: A Systematic Literature Review
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(3):149-159
07-10-2023- Laís Lage de Carvalho ,
- Júlia Magna da Silva Teixeira ,
- Roberto José Gervásio Unger ,
- Vivian Genaro Motti ,
- Giovanni Marcos Lovisi ,
- Fabiane Rossi dos Santos Grincenkov
Views180See moreAbstract
Objective:
This article aims to review the literature regarding the use of technologies to promote mental health for pregnant women. We seek to: understand the strategies that pregnant women use for mental health care. Also, we investigate the existence of scientific evidence that validates such practices.
Methods:
This study follows the PRISMA guidelines for systematic reviews. We analyze 27 studies published between 2012 and 2019. We include publications in Portuguese, English, and Spanish.
Results:
The results revealed several different possibilities to use technology, including the use of text messages and mobile applications on smartphones. Mobile applications are the most commonly used approaches (22.5%). Regarding the strategies used, cognitive-behavioral approaches, including mood checks, relaxation exercises, and psychoeducation comprised 44.12% of the content.
Conclusion:
There is a need for further investigation and research and development efforts in this field to better understand the possibilities of intervention in mental health in the digital age.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- Laís Lage de Carvalho
-
Original Article
Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
- Juliana Fernandes Medeiros ,
- Ana Cláudia Rabelo e Silva ,
- Natália Domene Franco da Rocha ,
- Alexia Viegas Georg ,
- Patricia Pereira dos Santos Melli , [ ... ],
- Geraldo Duarte
07-10-2023
Summary
Original ArticleSeroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(2):059-064
07-10-2023- Juliana Fernandes Medeiros ,
- Ana Cláudia Rabelo e Silva ,
- Natália Domene Franco da Rocha ,
- Alexia Viegas Georg ,
- Patricia Pereira dos Santos Melli ,
- Silvana Maria Quintana ,
- Geraldo Duarte
Views157See moreAbstract
Objective
To evaluate the seroprevalence of toxoplasmosis among puerperal women cared for at a tertiary university hospital and the level of understanding of these puerperal women about toxoplasmosis, vertical transmission, and its prophylaxis.
Methods
For this cross-sectional study, we evaluated 225 patients using presential interviews, prenatal documentation, and electronic medical records. Data were stored using Research Electronic Data Capture (REDCap) software. Prevalence rates were estimated by the presence of reactive IgG antibodies against Toxoplasma gondii. Data analysis was performed using the chi-square test and calculation of the odds ratio (OR). Seroreactivity to T. gondii and exposure variables (age, educational level, and parity) were analyzed using a confidence interval (95%CI) and a significance level of 5% (p < 0.05).
Results
The seropositivity rate for T. gondii was 40%. There was no association between seroprevalence and age. Primiparity was a protective factor against seropositivity and low education was a risk factor.
Conclusion
Knowledge of T. gondii infection and its transmission forms was significantly limited, presenting a risk for acute maternal toxoplasmosis and vertical transmission of this protozoan. Increasing the education level regarding the risk of toxoplasmosis during pregnancy could reduce the rates of infection and vertical transmission of this parasite.
Views157This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleSeroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(2):059-064
07-10-2023- Juliana Fernandes Medeiros ,
- Ana Cláudia Rabelo e Silva ,
- Natália Domene Franco da Rocha ,
- Alexia Viegas Georg ,
- Patricia Pereira dos Santos Melli ,
- Silvana Maria Quintana ,
- Geraldo Duarte
Views157See moreAbstract
Objective
To evaluate the seroprevalence of toxoplasmosis among puerperal women cared for at a tertiary university hospital and the level of understanding of these puerperal women about toxoplasmosis, vertical transmission, and its prophylaxis.
Methods
For this cross-sectional study, we evaluated 225 patients using presential interviews, prenatal documentation, and electronic medical records. Data were stored using Research Electronic Data Capture (REDCap) software. Prevalence rates were estimated by the presence of reactive IgG antibodies against Toxoplasma gondii. Data analysis was performed using the chi-square test and calculation of the odds ratio (OR). Seroreactivity to T. gondii and exposure variables (age, educational level, and parity) were analyzed using a confidence interval (95%CI) and a significance level of 5% (p < 0.05).
Results
The seropositivity rate for T. gondii was 40%. There was no association between seroprevalence and age. Primiparity was a protective factor against seropositivity and low education was a risk factor.
Conclusion
Knowledge of T. gondii infection and its transmission forms was significantly limited, presenting a risk for acute maternal toxoplasmosis and vertical transmission of this protozoan. Increasing the education level regarding the risk of toxoplasmosis during pregnancy could reduce the rates of infection and vertical transmission of this parasite.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- Juliana Fernandes Medeiros
Pregnancy Archives - Revista Brasileira de Ginecologia e Obstetrícia
