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Original Article12-11-2023
Obstetric and Perinatal Outcomes in Pregnant Women with Lupus: Retrospective Study in a Portuguese Tertiary Center
- InêsFerreira Jorge
, - JoanaMourão Vieitez Frade ,
- SusanaPaula Leonardo Dias Abreu Capela ,
- AndréLaboreiro Ferreira Mendes da Graça ,
- MariaLuísa Aleixo Gomes Pinto Grilo , [ ... ],
- AnaMónica Miguel Mendonça de Castro Centeno
Abstract
Original ArticleObstetric and Perinatal Outcomes in Pregnant Women with Lupus: Retrospective Study in a Portuguese Tertiary Center
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(10):568-574
- InêsFerreira Jorge ,
- JoanaMourão Vieitez Frade ,
- SusanaPaula Leonardo Dias Abreu Capela ,
- AndréLaboreiro Ferreira Mendes da Graça ,
- MariaLuísa Aleixo Gomes Pinto Grilo ,
- AnaMónica Miguel Mendonça de Castro Centeno
Views244See moreAbstract
Objective
Pregnancy in women with lupus poses a higher risk of complications compared with the general population. The present study aimed to determine and describe the obstetric and neonatal outcomes of pregnant women with lupus.
Materials and Methods
We conducted an observational retrospective study of pregnant women with the diagnosis of lupus, who were selected and followed at the Maternal-Fetal Medicine Clinic of our institution between January 2013 and July 2018. We analyzed 59 pregnancies and 52 newborns, and collected data regarding sociodemographic features, the preconception period, pregnancy, childbirth, postpartum and the newborn. A descriptive analysis of the variables was performed.
Results
In 58% of the cases, the pregnancy was uneventful. We registered flares in 25% of the cases, preeclampsia in 3%, fetal growth restriction in 12%, gestational loss in 10%, preterm labor in 10%, postpartum complications in 20%, and small for gestational age newborns in 17% of the cases.
Conclusions
Most pregnancies in women with lupus have favorable obstetric and neonatal outcomes. Prenatal counseling, adequate multidisciplinary surveillance, and optimized treatment of the disease are fundamental pillars for these good results.
Views244
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleObstetric and Perinatal Outcomes in Pregnant Women with Lupus: Retrospective Study in a Portuguese Tertiary Center
Revista Brasileira de Ginecologia e Obstetrícia. 2023;45(10):568-574
- InêsFerreira Jorge ,
- JoanaMourão Vieitez Frade ,
- SusanaPaula Leonardo Dias Abreu Capela ,
- AndréLaboreiro Ferreira Mendes da Graça ,
- MariaLuísa Aleixo Gomes Pinto Grilo ,
- AnaMónica Miguel Mendonça de Castro Centeno
Views244See moreAbstract
Objective
Pregnancy in women with lupus poses a higher risk of complications compared with the general population. The present study aimed to determine and describe the obstetric and neonatal outcomes of pregnant women with lupus.
Materials and Methods
We conducted an observational retrospective study of pregnant women with the diagnosis of lupus, who were selected and followed at the Maternal-Fetal Medicine Clinic of our institution between January 2013 and July 2018. We analyzed 59 pregnancies and 52 newborns, and collected data regarding sociodemographic features, the preconception period, pregnancy, childbirth, postpartum and the newborn. A descriptive analysis of the variables was performed.
Results
In 58% of the cases, the pregnancy was uneventful. We registered flares in 25% of the cases, preeclampsia in 3%, fetal growth restriction in 12%, gestational loss in 10%, preterm labor in 10%, postpartum complications in 20%, and small for gestational age newborns in 17% of the cases.
Conclusions
Most pregnancies in women with lupus have favorable obstetric and neonatal outcomes. Prenatal counseling, adequate multidisciplinary surveillance, and optimized treatment of the disease are fundamental pillars for these good results.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- InêsFerreira Jorge
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Original Article01-06-2011
Factors associated with low birth weight among adolescents in the Brazil Southeast region
Revista Brasileira de Ginecologia e Obstetrícia. 2011;33(10):286-291
Abstract
Original ArticleFactors associated with low birth weight among adolescents in the Brazil Southeast region
Revista Brasileira de Ginecologia e Obstetrícia. 2011;33(10):286-291
DOI 10.1590/S0100-72032011001000003
Views126PURPOSES: To determine the rate of low birth weight and some of the risk factors associated with this event among adolescents. METHODS: A cross-sectional study conducted between October 1994 and December 2009 at a maternity in Campinas, in Brazil, using information generated from the computerized obstetric form. After selection of adolescents who delivered at this hospital, two groups were created, with and without low birth weight, respectively. Relative risk and 95% confidence interval for all independent variables (risk factors) and the Χ2 test for some perinatal results were performed. The level of significance was set at 5%. RESULTS: During the study period, 24,000 births occurred at CAISM. Of these, 2,404 occurred among 2,357 teenagers (10.02%) and the frequency of low birth weight was 15.1%. Adolescent pregnancy recurred in 294 (8.2%). Age less than 15 years-old, anemia, smoking, and hypertension were not significantly associated with low birth weight. Antecedent of miscarriage and association with systemic lupus erythematosus increased the risk of low birth weight. Cesarean section and an Apgar score below seven were more prevalent among adolescents with low birth weight, and 85% of all adolescents had less than six prenatal visits. CONCLUSIONS: The prevalence of low birth weight is higher among adolescents than among adult women, and there was a large number of adolescents with less than six prenatal visits . The antecedent of miscarriage and the presence of systemic lupus erythematosus were risk factors associated with the occurrence of low birth weight among adolescents.
Key-words AbortionHigh risk pregnancyInfantLow birth weightLupus erythematosusPregnancy in adolescenceprematurePrenatal careRisk factorssystemicSee moreViews126This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract
Original ArticleFactors associated with low birth weight among adolescents in the Brazil Southeast region
Revista Brasileira de Ginecologia e Obstetrícia. 2011;33(10):286-291
DOI 10.1590/S0100-72032011001000003
Views126PURPOSES: To determine the rate of low birth weight and some of the risk factors associated with this event among adolescents. METHODS: A cross-sectional study conducted between October 1994 and December 2009 at a maternity in Campinas, in Brazil, using information generated from the computerized obstetric form. After selection of adolescents who delivered at this hospital, two groups were created, with and without low birth weight, respectively. Relative risk and 95% confidence interval for all independent variables (risk factors) and the Χ2 test for some perinatal results were performed. The level of significance was set at 5%. RESULTS: During the study period, 24,000 births occurred at CAISM. Of these, 2,404 occurred among 2,357 teenagers (10.02%) and the frequency of low birth weight was 15.1%. Adolescent pregnancy recurred in 294 (8.2%). Age less than 15 years-old, anemia, smoking, and hypertension were not significantly associated with low birth weight. Antecedent of miscarriage and association with systemic lupus erythematosus increased the risk of low birth weight. Cesarean section and an Apgar score below seven were more prevalent among adolescents with low birth weight, and 85% of all adolescents had less than six prenatal visits. CONCLUSIONS: The prevalence of low birth weight is higher among adolescents than among adult women, and there was a large number of adolescents with less than six prenatal visits . The antecedent of miscarriage and the presence of systemic lupus erythematosus were risk factors associated with the occurrence of low birth weight among adolescents.
Key-words AbortionHigh risk pregnancyInfantLow birth weightLupus erythematosusPregnancy in adolescenceprematurePrenatal careRisk factorssystemicSee moreThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Lupus erythematosus Archives - Revista Brasileira de Ginecologia e Obstetrícia
