HIV, prenatal serodiagnosis Archives - Revista Brasileira de Ginecologia e Obstetrícia

  • Original Article07-16-2001

    Rapid test to detect HIV-1 infection among pregnant women

    Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(2):107-111

    Abstract

    Original Article

    Rapid test to detect HIV-1 infection among pregnant women

    Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(2):107-111

    DOI 10.1590/S0100-72032001000200008

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    Purpose: to evaluate the results of a rapid diagnostic test for HIV-1 infection made available by the Health Ministry for the identification of pregnant women contaminated by this virus. Methods: we evaluated prospectively 443 pregnant women with no prenatal serologic anti-HIV test seen at the Department of Gynecology and Obstetrics of the Faculty of Medicine of Ribeirão Preto, University of São Paulo, from February to June, 2000. Samples from these patients were submitted to the rapid immunochromatographic test, which was compared with ELISA and submitted to a confirmatory agglutination test. Results: among the 443 pregnant women submitted to the rapid test (20.1% of the deliveries performed during the study period), 16 showed positive results (3.6%). No sample with a negative result by the rapid test was positive by ELISA. However, of the 16 samples that were positive by the rapid test, two were negative by the confirmatory tests. Thus, the rapid test showed 100.0% sensitivity, 99.5% specificity, 87.5% positive predictive value, and 100.0% negative predictive value. Conclusions: the results obtained by evaluation of the test for a rapid diagnosis of HIV-1 infection in pregnant women revealed sensitivity, specificity and predictive values that qualify it as an extremely important resource for the indication of measures that will reduce perinatal transmission of this virus.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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