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Review Article
Use of Corticosteroids in Prenatal Treatment of Congenital Pulmonary Adenomatoid Malformation: Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):304-310
02-02-2022
Summary
Review ArticleUse of Corticosteroids in Prenatal Treatment of Congenital Pulmonary Adenomatoid Malformation: Integrative Review
Revista Brasileira de Ginecologia e Obstetrícia. 2022;44(3):304-310
02-02-2022Views116Abstract
Objective
To review data on the use of corticosteroids for the treatment of fetuses with high-risk congenital pulmonary adenomatoid malformation (CPAM).
Methods
Integrative review based on the literature available onMEDLINE and LILACS, including articles published until November, 2020.
Results
The initial search resulted in 87 articles, 4 of which were selected for analysis, with all of them being retrospective descriptive observational studies. In the group of fetuses that received only a single corticosteroid cycle, the hydrops resolution rate was 70%, and the survival rate was 83.8%. In fetuses treated with 2 or more cycles of corticosteroids, there was an improvement in the condition of hydrops or edema in a single body compartment in 47%, and survival of 81.8% of the fetuses.
Conclusion
The use of corticosteroids for the prenatal treatment of high-risk CPAM appears to be associated with an improvement in perinatal outcomes.
Key-words Betamethasonecongenital pulmonary adenomatoid malformationcorticosteroidFetal treatmenthydropsSee more -
Editorial
Fetal surgery in Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2011;33(4):153-156
08-05-2011
Summary
EditorialFetal surgery in Brazil
Revista Brasileira de Ginecologia e Obstetrícia. 2011;33(4):153-156
08-05-2011DOI 10.1590/S0100-72032011000400001
Views81A postagem não tem conteúdoKey-words Congenital diaphragmatic herniaCongenital heart defectFetal surgeryFetal treatmentLower urinary tract obstructionSee more