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Original Article
Placental Sampling for Understanding Viral Infections – A Simplified Protocol for the COVID-19 Pandemic
- Guilherme de Moraes Nobrega
, - José Paulo Siqueira Guida ,
- Rodolfo Rosa Japecanga ,
- Arthur Antolini-Tavares ,
- Indira Mysorekar , [ ... ],
- Maria Laura Costa
07-30-2021
Summary
Original ArticlePlacental Sampling for Understanding Viral Infections – A Simplified Protocol for the COVID-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):377-383
07-30-2021- Guilherme de Moraes Nobrega ,
- José Paulo Siqueira Guida ,
- Rodolfo Rosa Japecanga ,
- Arthur Antolini-Tavares ,
- Indira Mysorekar ,
- Maria Laura Costa
Views136See moreAbstract
Objective
The coronavirus disease 2019 (COVID-19) is a pandemic viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The impact of the disease among the obstetric population remains unclear, and the study of the placenta can provide valuable information. Adequate sampling of the placental tissue can help characterize the pathways of viral infections.
Methods
A protocol of placental sampling is proposed, aiming at guaranteeing representativity of the placenta and describing the adequate conservation of samples and their integrity for future analysis. The protocol is presented in its complete and simplified versions, allowing its implementation in different complexity settings.
Results
Sampling with the minimum possible interval from childbirth is the key for adequate sampling and storage. This protocol has already been implemented during the Zika virus outbreak.
Conclusion
A protocol for adequate sampling and storage of placental tissue is fundamental for adequate evaluation of viral infections on the placenta. During the COVID-19 pandemic, implementation of this protocol may help to elucidate critical aspects of the SARS-CoV-2 infection.
Views136
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticlePlacental Sampling for Understanding Viral Infections – A Simplified Protocol for the COVID-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(5):377-383
07-30-2021- Guilherme de Moraes Nobrega ,
- José Paulo Siqueira Guida ,
- Rodolfo Rosa Japecanga ,
- Arthur Antolini-Tavares ,
- Indira Mysorekar ,
- Maria Laura Costa
Views136See moreAbstract
Objective
The coronavirus disease 2019 (COVID-19) is a pandemic viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The impact of the disease among the obstetric population remains unclear, and the study of the placenta can provide valuable information. Adequate sampling of the placental tissue can help characterize the pathways of viral infections.
Methods
A protocol of placental sampling is proposed, aiming at guaranteeing representativity of the placenta and describing the adequate conservation of samples and their integrity for future analysis. The protocol is presented in its complete and simplified versions, allowing its implementation in different complexity settings.
Results
Sampling with the minimum possible interval from childbirth is the key for adequate sampling and storage. This protocol has already been implemented during the Zika virus outbreak.
Conclusion
A protocol for adequate sampling and storage of placental tissue is fundamental for adequate evaluation of viral infections on the placenta. During the COVID-19 pandemic, implementation of this protocol may help to elucidate critical aspects of the SARS-CoV-2 infection.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Guilherme de Moraes Nobrega
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Review Article
SARS-CoV-2 Infection and Placental Pathology Infecção por SARS-CoV-2 e patologia placentária
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):474-479
06-02-2021
Summary
Review ArticleSARS-CoV-2 Infection and Placental Pathology Infecção por SARS-CoV-2 e patologia placentária
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):474-479
06-02-2021Views187See moreAbstract
Placental pathophysiology in SARS-CoV-2 infection can help researchers understand more about the infection and its impact on thematernal/neonatal outcomes. This brief review provides an overview about some aspects of the placental pathology in SARSCoV- 2 infection. In total, 11 papers were included. The current literature suggests that there are no specific histopathological characteristics in the placenta related to SARSCoV- 2 infection, but placentas frominfected women aremore likely to show findings of maternal and/or fetal malperfusion. The most common findings in placentas from infected women were fibrin deposition and intense recruitment of inflammatory infiltrates. The transplacental transmission of this virus is unlikely to occur, probably due to low expression of the receptor for SARS-CoV-2 in placental cell types. Further studies are needed to improve our knowledge about the interaction between the virus and the mother-fetus dyad and the impact on maternal and neonatal/fetal outcomes.
Views187This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleSARS-CoV-2 Infection and Placental Pathology Infecção por SARS-CoV-2 e patologia placentária
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(6):474-479
06-02-2021Views187See moreAbstract
Placental pathophysiology in SARS-CoV-2 infection can help researchers understand more about the infection and its impact on thematernal/neonatal outcomes. This brief review provides an overview about some aspects of the placental pathology in SARSCoV- 2 infection. In total, 11 papers were included. The current literature suggests that there are no specific histopathological characteristics in the placenta related to SARSCoV- 2 infection, but placentas frominfected women aremore likely to show findings of maternal and/or fetal malperfusion. The most common findings in placentas from infected women were fibrin deposition and intense recruitment of inflammatory infiltrates. The transplacental transmission of this virus is unlikely to occur, probably due to low expression of the receptor for SARS-CoV-2 in placental cell types. Further studies are needed to improve our knowledge about the interaction between the virus and the mother-fetus dyad and the impact on maternal and neonatal/fetal outcomes.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Systematic Review
Vertical Transmission of SARS-CoV-2: A Systematic Review
- Ionara Diniz Evangelista Santos Barcelos ,
- Ivan Andrade de Araújo Penna ,
- Adriana de Góes Soligo ,
- Zelma Bernardes Costa ,
- Wellington Paula Martins
05-24-2021
Summary
Systematic ReviewVertical Transmission of SARS-CoV-2: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(3):207-215
05-24-2021- Ionara Diniz Evangelista Santos Barcelos ,
- Ivan Andrade de Araújo Penna ,
- Adriana de Góes Soligo ,
- Zelma Bernardes Costa ,
- Wellington Paula Martins
Views191See moreAbstract
Objective
The evaluation of the available evidence on vertical transmission by severe acute respiratory syndrome coronavirus 2 (SARS-CoV)-2.
Data Sources
An electronic search was performed on June 13, 2020 on the Embase, PubMed and Scopus databases using the following search terms: (Coronavirus OR COVID-19 OR COVID19 OR SARS-CoV-2 OR SARS-CoV2 OR SARSCoV2) AND (vertical OR pregnancy OR fetal).
Selection of Studies
The electronic search resulted in a total of 2,073 records. Titles and abstracts were reviewed by two authors (WPM, IDESB), who checked for duplicates using the pre-established criteria for screening (studies published in English without limitation regarding the date or the status of the publication).
Data Collection
Data extraction was performed in a standardized way, and the final eligibility was assessed by reading the full text of the articles. We retrieved data regarding the delivery of the potential cases of vertical transmission, as well as themain findings and conclusions of systematic reviews.
Data Synthesis
The 2,073 records were reviewed; 1,000 duplicates and 896 clearly not eligible records were excluded. We evaluated the full text of 177 records, and identified only 9 suspected cases of possible vertical transmission. The only case with sufficient evidence of vertical transmission was reported in France.
Conclusion
The risk of vertical transmission by SARS-CoV-2 is probably very low. Despite several thousands of affected pregnant women, we have identified only one case that has fulfilled sufficient criteria to be confirmed as a case of vertical transmission. Well-designed observational studies evaluating large samples are still necessary to determine the risk of vertical transmission depending on the gestational age at infection.
Views191This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Systematic ReviewVertical Transmission of SARS-CoV-2: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(3):207-215
05-24-2021- Ionara Diniz Evangelista Santos Barcelos ,
- Ivan Andrade de Araújo Penna ,
- Adriana de Góes Soligo ,
- Zelma Bernardes Costa ,
- Wellington Paula Martins
Views191See moreAbstract
Objective
The evaluation of the available evidence on vertical transmission by severe acute respiratory syndrome coronavirus 2 (SARS-CoV)-2.
Data Sources
An electronic search was performed on June 13, 2020 on the Embase, PubMed and Scopus databases using the following search terms: (Coronavirus OR COVID-19 OR COVID19 OR SARS-CoV-2 OR SARS-CoV2 OR SARSCoV2) AND (vertical OR pregnancy OR fetal).
Selection of Studies
The electronic search resulted in a total of 2,073 records. Titles and abstracts were reviewed by two authors (WPM, IDESB), who checked for duplicates using the pre-established criteria for screening (studies published in English without limitation regarding the date or the status of the publication).
Data Collection
Data extraction was performed in a standardized way, and the final eligibility was assessed by reading the full text of the articles. We retrieved data regarding the delivery of the potential cases of vertical transmission, as well as themain findings and conclusions of systematic reviews.
Data Synthesis
The 2,073 records were reviewed; 1,000 duplicates and 896 clearly not eligible records were excluded. We evaluated the full text of 177 records, and identified only 9 suspected cases of possible vertical transmission. The only case with sufficient evidence of vertical transmission was reported in France.
Conclusion
The risk of vertical transmission by SARS-CoV-2 is probably very low. Despite several thousands of affected pregnant women, we have identified only one case that has fulfilled sufficient criteria to be confirmed as a case of vertical transmission. Well-designed observational studies evaluating large samples are still necessary to determine the risk of vertical transmission depending on the gestational age at infection.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
- Ionara Diniz Evangelista Santos Barcelos
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Original Article
Comparison of Laboratory and Radiological Findings of Pregnant and Non-PregnantWomen with Covid-19
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(3):200-206
05-24-2021
Summary
Original ArticleComparison of Laboratory and Radiological Findings of Pregnant and Non-PregnantWomen with Covid-19
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(3):200-206
05-24-2021Views119See moreAbstract
Objective
Covid-19 became a pandemic, and researchers have not been able to establish a treatment algorithm. The pregnant population is also another concern for health care professionals. There are physiological changes related to pregnancy that result in different laboratory levels, radiological findings and disease progression. The goal of the present article is to determine whether the laboratory results and radiological findings were different in non-pregnant women (NPWs) of reproductive age and pregnant women (PWs) diagnosed with the Covid-19 infection.
Methods
Out of 34 patients, 15 (44.11%) PWs and 19 (55.8%) NPWs were included in the study. Age, comorbidities, complaints, vitals, respiratory rates, computed tomography (CT) findings and stages, as well as laboratory parameters, were recorded from the hospital database.
Results
Themean age of the PWs was of 27.6 ± 0.99 years, and that of the NPWs was of 37.63 ± 2.00; when agewas compared between the groups, a statistically significant difference (p=0.001) was found. The mean systolic blood pressure of the PWs was of 116.53 ± 11.35, and that of the NPWs was of 125.53 ± 13.00, and their difference was statistically significant (p=0.05). The difference in the minimum respiratory rates of the patients was also statistically significant (p=0.05). The platelet levels observed among the PWs with Covid-19 were lower than those of the NPWs (185.40 ± 39.09 x 109/mcL and 232.00 ± 71.04 x 109/mcL respectively; p=0.05). The mean D-dimer value of the PWs was lower in comparison to that of the NPWs (p<0.05).
Conclusion
The laboratory findings and imaging studiesmay differ between pregnant and non-pregnant populations. It is important to properly interpret these studies. Future studies with a higher number of patients are required to confirm these preliminary data.
Views119This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Original ArticleComparison of Laboratory and Radiological Findings of Pregnant and Non-PregnantWomen with Covid-19
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(3):200-206
05-24-2021Views119See moreAbstract
Objective
Covid-19 became a pandemic, and researchers have not been able to establish a treatment algorithm. The pregnant population is also another concern for health care professionals. There are physiological changes related to pregnancy that result in different laboratory levels, radiological findings and disease progression. The goal of the present article is to determine whether the laboratory results and radiological findings were different in non-pregnant women (NPWs) of reproductive age and pregnant women (PWs) diagnosed with the Covid-19 infection.
Methods
Out of 34 patients, 15 (44.11%) PWs and 19 (55.8%) NPWs were included in the study. Age, comorbidities, complaints, vitals, respiratory rates, computed tomography (CT) findings and stages, as well as laboratory parameters, were recorded from the hospital database.
Results
Themean age of the PWs was of 27.6 ± 0.99 years, and that of the NPWs was of 37.63 ± 2.00; when agewas compared between the groups, a statistically significant difference (p=0.001) was found. The mean systolic blood pressure of the PWs was of 116.53 ± 11.35, and that of the NPWs was of 125.53 ± 13.00, and their difference was statistically significant (p=0.05). The difference in the minimum respiratory rates of the patients was also statistically significant (p=0.05). The platelet levels observed among the PWs with Covid-19 were lower than those of the NPWs (185.40 ± 39.09 x 109/mcL and 232.00 ± 71.04 x 109/mcL respectively; p=0.05). The mean D-dimer value of the PWs was lower in comparison to that of the NPWs (p<0.05).
Conclusion
The laboratory findings and imaging studiesmay differ between pregnant and non-pregnant populations. It is important to properly interpret these studies. Future studies with a higher number of patients are required to confirm these preliminary data.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 
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Review Article
COVID-19: Uncertainties from Conception to Birth
- Bruno Ramalho de Carvalho ,
- Karina de Sá Adami ,
- Walusa Assad Gonçalves-Ferri ,
- Marise Samama ,
- Rui Alberto Ferriani , [ ... ],
- Alessandra Cristina Marcolin
03-08-2021
Summary
Review ArticleCOVID-19: Uncertainties from Conception to Birth
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(1):54-60
03-08-2021- Bruno Ramalho de Carvalho ,
- Karina de Sá Adami ,
- Walusa Assad Gonçalves-Ferri ,
- Marise Samama ,
- Rui Alberto Ferriani ,
- Alessandra Cristina Marcolin
Views138See moreAbstract
Scientific information on the impact of the new coronavirus (SARS-CoV-2) on the health of pregnant women, fetuses and newborns is considered of limited confidence, lacking good-quality evidence, and drawing biased conclusions. As a matter of fact, the initial impressions that the evolution of COVID-19 was no different between pregnant and non-pregnant women, and that SARS-CoV-2 was not vertically transmitted, are confronted by the documentation of worsening of the disease during pregnancy, poor obstetric outcomes, and the possibility of vertical transmission. The present article aims to compile the data available on the association of COVID-19 and reproductive events, from conception to birth.
Views138This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleCOVID-19: Uncertainties from Conception to Birth
Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(1):54-60
03-08-2021- Bruno Ramalho de Carvalho ,
- Karina de Sá Adami ,
- Walusa Assad Gonçalves-Ferri ,
- Marise Samama ,
- Rui Alberto Ferriani ,
- Alessandra Cristina Marcolin
Views138See moreAbstract
Scientific information on the impact of the new coronavirus (SARS-CoV-2) on the health of pregnant women, fetuses and newborns is considered of limited confidence, lacking good-quality evidence, and drawing biased conclusions. As a matter of fact, the initial impressions that the evolution of COVID-19 was no different between pregnant and non-pregnant women, and that SARS-CoV-2 was not vertically transmitted, are confronted by the documentation of worsening of the disease during pregnancy, poor obstetric outcomes, and the possibility of vertical transmission. The present article aims to compile the data available on the association of COVID-19 and reproductive events, from conception to birth.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Bruno Ramalho de Carvalho
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Review Article
Gynecological Surgery and COVID-19: What is the Impact and How Should I Manage it?
- Julio Cesar Rosa-e-Silva ,
- Paulo Ayroza Ribeiro ,
- Luiz Gustavo Oliveira Brito ,
- Mariano Tamura Vieira Gomes ,
- Sergio Podgaec , [ ... ],
- Agnaldo Lopes da Silva Filho
08-26-2020
Summary
Review ArticleGynecological Surgery and COVID-19: What is the Impact and How Should I Manage it?
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(7):415-419
08-26-2020- Julio Cesar Rosa-e-Silva ,
- Paulo Ayroza Ribeiro ,
- Luiz Gustavo Oliveira Brito ,
- Mariano Tamura Vieira Gomes ,
- Sergio Podgaec ,
- Helizabet Salomão Abdalla Ayroza Ribeiro ,
- Carlos Augusto Pires Costa Lino ,
- Ricardo Quintairos ,
- Walquiria Quida Salles Pereira Primo ,
- Agnaldo Lopes da Silva Filho
Views187See moreAbstract
It is estimated that around 28 million surgeries will be postponed or canceled worldwide as a result of this pandemic, causing a delay in the diagnosis and treatment of more than 2 million cancer cases. In Brazil, both the National Health Agency (ANS) and National Health Surveillance Agency (ANVISA) advised the postponement of elective and non-essential surgeries, causing a considerable impact on the number of surgical procedures that decreased by 33.4% in this period. However, some women need treatment for various gynecological diseases that cannot be postponed. The purpose of this article is to present recommendations on surgical treatment during the COVID-19 pandemic.
Views187This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleGynecological Surgery and COVID-19: What is the Impact and How Should I Manage it?
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(7):415-419
08-26-2020- Julio Cesar Rosa-e-Silva ,
- Paulo Ayroza Ribeiro ,
- Luiz Gustavo Oliveira Brito ,
- Mariano Tamura Vieira Gomes ,
- Sergio Podgaec ,
- Helizabet Salomão Abdalla Ayroza Ribeiro ,
- Carlos Augusto Pires Costa Lino ,
- Ricardo Quintairos ,
- Walquiria Quida Salles Pereira Primo ,
- Agnaldo Lopes da Silva Filho
Views187See moreAbstract
It is estimated that around 28 million surgeries will be postponed or canceled worldwide as a result of this pandemic, causing a delay in the diagnosis and treatment of more than 2 million cancer cases. In Brazil, both the National Health Agency (ANS) and National Health Surveillance Agency (ANVISA) advised the postponement of elective and non-essential surgeries, causing a considerable impact on the number of surgical procedures that decreased by 33.4% in this period. However, some women need treatment for various gynecological diseases that cannot be postponed. The purpose of this article is to present recommendations on surgical treatment during the COVID-19 pandemic.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Julio Cesar Rosa-e-Silva
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Review Article
Covid-19 and Pregnancy: An Overview
- Pedro Castro ,
- Ana Paula Matos ,
- Heron Werner ,
- Flávia Paiva Lopes ,
- Gabriele Tonni , [ ... ],
- Edward Araujo Júnior
08-26-2020
Summary
Review ArticleCovid-19 and Pregnancy: An Overview
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(7):420-426
08-26-2020- Pedro Castro ,
- Ana Paula Matos ,
- Heron Werner ,
- Flávia Paiva Lopes ,
- Gabriele Tonni ,
- Edward Araujo Júnior
Views169See moreAbstract
Since the World Health Organization (WHO) declared coronavirus infection (COVID-19) a Public Health Emergency of International Concern in January 2020, there have been many concerns about pregnant women and the possible effects of this emergency with catastrophic outcomes inmany countries. Information on COVID-19 and pregnancy are scarce and spread throughout a fewcase series, with no more than 50 cases in total. The present review provides a brief analysis of COVID-19, pregnancy in the COVID-19 era, and the effects of COVID-19 on pregnancy.
Views169This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Review ArticleCovid-19 and Pregnancy: An Overview
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(7):420-426
08-26-2020- Pedro Castro ,
- Ana Paula Matos ,
- Heron Werner ,
- Flávia Paiva Lopes ,
- Gabriele Tonni ,
- Edward Araujo Júnior
Views169See moreAbstract
Since the World Health Organization (WHO) declared coronavirus infection (COVID-19) a Public Health Emergency of International Concern in January 2020, there have been many concerns about pregnant women and the possible effects of this emergency with catastrophic outcomes inmany countries. Information on COVID-19 and pregnancy are scarce and spread throughout a fewcase series, with no more than 50 cases in total. The present review provides a brief analysis of COVID-19, pregnancy in the COVID-19 era, and the effects of COVID-19 on pregnancy.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Pedro Castro
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Special Article
Childbirth, Puerperium and Abortion Care Protocol during the COVID-19 Pandemic
- Alberto Trapani Júnior ,
- Laura Rassi Vanhoni ,
- Sheila Koettker Silveira ,
- Alessandra Cristina Marcolin
07-17-2020
Summary
Special ArticleChildbirth, Puerperium and Abortion Care Protocol during the COVID-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(6):349-355
07-17-2020- Alberto Trapani Júnior ,
- Laura Rassi Vanhoni ,
- Sheila Koettker Silveira ,
- Alessandra Cristina Marcolin
Views116See moreAbstract
The new coronavirus (severe acute respiratory syndrome-related coronavirus 2, SARSCoV- 2) is a virus that causes a potentially serious respiratory disease that has spread in several countries, reaching humans in all age groups, including pregnant women. The purpose of this protocol is to provide technical and scientific support to Brazilian obstetricians regarding childbirth, postpartum and abortion care during the pandemic.
Views116This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Summary
Special ArticleChildbirth, Puerperium and Abortion Care Protocol during the COVID-19 Pandemic
Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(6):349-355
07-17-2020- Alberto Trapani Júnior ,
- Laura Rassi Vanhoni ,
- Sheila Koettker Silveira ,
- Alessandra Cristina Marcolin
Views116See moreAbstract
The new coronavirus (severe acute respiratory syndrome-related coronavirus 2, SARSCoV- 2) is a virus that causes a potentially serious respiratory disease that has spread in several countries, reaching humans in all age groups, including pregnant women. The purpose of this protocol is to provide technical and scientific support to Brazilian obstetricians regarding childbirth, postpartum and abortion care during the pandemic.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. - Alberto Trapani Júnior
COVID-19 Archives - Revista Brasileira de Ginecologia e Obstetrícia
