caffeine Archives - Revista Brasileira de Ginecologia e Obstetrícia

  • Original Article

    Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeirão Preto

    Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(12):749-756

    Summary

    Original Article

    Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeirão Preto

    Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(12):749-756

    DOI 10.1055/s-0038-1675806

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    Abstract

    Objective

    To describe caffeine consumption during pregnancy and its association with low birth weight (LBW) and preterm birth in the birth cohort of Ribeirão Preto, state of São Paulo, Brazil, in 2010.

    Methods

    Cohort study, with descriptive and analytical approach. Data included 7,607 women and their newborns in Ribeirão Preto, state of São Paulo, Brazil. The women answered standardized questionnaires about reproductive health, prenatal care, life habits, sociodemographic conditions, and information about coffee intake. The independent variable was high caffeine consumption (≥300 mg/day) from coffee during pregnancy, and the dependent variables were LBW (birth weight < 2,500 g) and preterm birth (< 37 weeks of gestational age). Four adjusted polytomous logistic regression models, relative risk (RR) and 95% confidence interval (CI) were fitted: biological and sociodemographic conditions; obstetric history; current gestational conditions; and all variables included in the previous models.

    Results

    A total of 4,908 (64.5%) mothers consumed caffeine, 143 (2.9%) of whom reported high consumption. High caffeine intake was significantly associated with reduced education and with the occupation of the head of the family, nonwhite skin color, not having a partner, higher parity, previous abortion and preterm birth, urinary tract infection, threatened abortion, alcohol consumption and smoking. No association was found between high caffeine consumption and LBW or preterm birth in both

    Conclusion

    In this cohort, high caffeine intake was lower than in other studies and no association with LBW or preterm birth was found.

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  • Artigos Originais

    Caffeine consumption by pregnant women selected from a Health Care Center in the municipality of Rio de Janeiro, Brazil

    Revista Brasileira de Ginecologia e Obstetrícia. 2008;30(5):232-240

    Summary

    Artigos Originais

    Caffeine consumption by pregnant women selected from a Health Care Center in the municipality of Rio de Janeiro, Brazil

    Revista Brasileira de Ginecologia e Obstetrícia. 2008;30(5):232-240

    DOI 10.1590/S0100-72032008000500005

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    PURPOSE: to determine caffeine consumption in pregnant women and to evaluate its association with demographic, socioeconomic, reproductive, lifestyle and maternal nutritional status. METHODS: it is a cross-sectional study performed between 2005 and 2007. The present analysis refers to the period among the 8th and 13th gestational week and included 255 pregnant women from 18 to 40 years, clients of a municipal health center in Rio de Janeiro. The outcome variable was caffeine consumption, quantified by a semi-quantitative food frequency questionnaire, which count with a list containing 81 items and eight options of consumption frequencies; besides it being previously validated in a sample of employees of the State University of Rio de Janeiro. The caffeine intake was quantified starting from the consumption of: powdered chocolate, chocolate bar or chocolate, soft drink, coffee and mate tea. The statistical analysis was performed by means of fitting a multivariate linear regression. RESULTS: the median and the mean caffeine consumption were, respectively, 97.5 and 121.1 mg (standard deviation, sd = 128.4). The high caffeine consumption (> 300 mg/day) was observed in 8.3% of pregnant women. It was observed in the multivariate model that women with earlier menarche (β = -0.15), with more household partners (b = 0.17) and who didn’t make use of medicines (β = -0.24) presented larger tendency to high caffeine consumption association that was statistically significant (p <0.05). CONCLUSIONS: the caffeine consumption for most of the pregnant women was inferior to the limit of 300 mg/day as commited in other studies. Tendency was observed toward higher consumption of caffeine in pregnant women with earlier menarche, with more household partners and who didn’t make use of medicines.

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