You searched for:"Vera Therezinha Medeiros Borges"
We found (9) results for your search.Summary
Rev Bras Ginecol Obstet. 2023;45(3):109-112
Summary
Rev Bras Ginecol Obstet. 2022;44(12):1122-1125
Summary
Rev Bras Ginecol Obstet. 2001;23(3):147-151
DOI 10.1590/S0100-72032001000300003
Purpose: to evaluate maternal hemodynamic and cardiac structural changes during the three trimesters of pregnancy and to relate them to the weight/gestational age of the newborn. Methods: twenty-two healthy pregnant women were submitted to echocardiography for the study of cardiac output, mean arterial pressure, left atrium diameter, and peripheral resistance during three periods of pregnancy, i.e., before the 12th week and at the 26thand 36th weeks of pregnancy. Seventeen pregnant women gave birth to infants with adequate weight for gestational age, four gave birth to small for gestational age newborns and one gave birth to a large for gestational age infant. Results: among mothers of low weight newborns, cardiac output and left atrium diameter remained constant, mean arterial pressure showed a tendency to increase and peripheral resistance was significantly increased (28%), during the gestation. Among the mothers of adequate weight newborns there was an increase in cardiac output of 19% in the second trimester and 8% in the third. The left atrial diameter increased approximately 9% during the gestation, with maintenance of mean arterial pressure and a tendency to a decrease in peripheral resistance. Conclusion: the present results support an association between hemodynamic adaptation and weight newborn.
Summary
Rev Bras Ginecol Obstet. 1998;20(4):225-225
DOI 10.1590/S0100-72031998000400009
Summary
Rev Bras Ginecol Obstet. 2019;41(5):318-332
Pre-eclampsia is a multifactorial and multisystemic disease specific to gestation. It is classically diagnosed by the presence of hypertension associated with proteinuria manifested in a previously normotensive pregnant woman after the 20th week of gestation. Pre-eclampsia is also considered in the absence of proteinuria if there is target organ damage. The present review takes a general approach focused on aspects of practical interest in the clinical and obstetric care of these women. Thus, it explores the still unknown etiology, current aspects of pathophysiology and of the diagnosis, the approach to disease prediction, its adverse outcomes and prevention. Management is based on general principles, on nonpharmacological and on pharmacological clinical treatment of severe or nonsevere situations with emphasis on the hypertensive crisis and eclampsia. Obstetric management is based on preeclampsia without or with signs of clinical and/or laboratory deterioration, stratification of gestational age
Summary
Rev Bras Ginecol Obstet. 2002;24(5):329-334
DOI 10.1590/S0100-72032002000500007
Purpose: to evaluate the effect of total abdominal hysterectomy on ovarian blood supply in women in reproductive age, using transvaginal color Doppler. Methods: a prospective study was carried out on 61 40-year-old or younger women. They were divided into two groups: G1, 31 patients submitted to hysterectomy, and G2, 30 normal women. Criteria of inclusion: normal ovarian function at baseline, normal body weight, without expasure to tobacco, no history of laparotomy or ovarian pathology. The pulsatility index (PI) of ovarian arteries determined by Doppler and the transvaginal ultrasonographic measurement of the ovarian volume were performed at three moments: baseline, 6 and 12 months. Results: at baseline the groups were homogeneous. In the hysterectomized group, with 6 and 12 months, increase of the volume of the ovaries and decrease of PI (p<0,05) were observed. At the end of the study, 25.5% (8/31) of the hysterectomized patients presented benign ovarian cysts. In the control group no alteration of the parameters was observed. Conclusion: The decrease of PI by Doppler of ovarian arteries suggests increased ovarian blood supply after total abdominal hysterectomy in women in reproductive age.
Summary
Rev Bras Ginecol Obstet. 2003;25(6):445-448
DOI 10.1590/S0100-72032003000600010
Development of preeclampsia/eclampsia prior to 20 weeks of pregnancy should raise the suspicion of hydatidiform mole. We report a case of complete hydatidiform mole (CHM) concurrent with eclampsia in a 20-year-old patient with vaginal bleeding, anemia, large uterine size, and ovary cysts associated with hypertension and proteinuria. Plasmatic b-hCG levels were high and there was abnormal thyroid function. The ultrasonographic findings were compatible with CHM. After uterine evacuation, the patient had headache and visual alterations, followed by tonic-clonic seizures, which ceased with the administration of 50% magnesium sulfate. At post-molar follow-up, a gestational trophoblastic tumor (GTT) was diagnosed and promptly treated with chemotherapy. Association between CHM and eclampsia requires immediate uterine evacuation and strict post-molar follow-up, due to increased risk of GTT development.
Summary
Rev Bras Ginecol Obstet. 2021;43(9):669-675
Preeclampsia (PE) is a pregnancy-specific syndrome characterized by abnormal levels of cytokines and angiogenic factors, playing a role in the disease development. The present study evaluated whether immunological markers are associated with the gestational age and with the disease severity in preeclamptic women.
Ninety-five women who developed PE were stratified for gestational age as preterm PE (< 37 weeks) and term PE (≥ 37 weeks of gestation) and compared for disease severity as well as plasma concentration of angiogenic factors and cytokines. The concentrations of placental growth factor (PlGF), vascular endothelial growth factor (VEGF), Fms-like soluble tyrosine kinase (sFlt-1) and soluble endoglin (sEng), as well as the cytokines, tumor necrosis factor-α (TNF-α) and interleukin 10 (IL-10), were determined by enzyme-linked immunosorbent assay (ELISA).
The comparison between preeclamptic groups showed a higher percentage of severe cases in preterm PE (82.1%) than in term PE (35.9%). Similarly, the concentrations of TNF-α, sFlt-1, and sEng, as well as TNF-α/IL-10 and sFlt-1/PlGF ratios were significantly higher in the preterm PE group. In contrast, concentrations of PlGF, VEGF, and IL-10 were significantly lower in women with preterm PE. Negative correlations between TNF-α and IL-10 (r = 0.5232) and between PlGF and sFlt1 (r = 0.4158) were detected in the preterm PE.
In pregnant women with preterm PE, there is an imbalance between immunological markers, with the predominance of anti-angiogenic factors and TNF-α, associated with adverse maternal clinical outcomes.