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  • Trabalhos Originais

    Influence of maternal age, pregnancy stage and number of pregnancies on human papillomavirus infection

    Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(1):33-35

    Summary

    Trabalhos Originais

    Influence of maternal age, pregnancy stage and number of pregnancies on human papillomavirus infection

    Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(1):33-35

    DOI 10.1590/S0100-72031998000100006

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    We have analyzed 93 pregnant women with Papanicolaou smears suggesting human papillomavirus (HPV) infection (Schneider et al's criteria) with the purpose of studying the effect of maternal age, stage of pregnancy and number of pregnancies on the incidence of this infection. The control group consisted of 93pregnant women with Papanicolaou smears not suggestive of HPV infection. The results demonstrated that HPV infection is associated with pregnant women under 20 years of age, but no differences were found regarding stage and number of pregnancies.

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  • Trabalhos Originais

    Frequency of human papillomavirus infection in women with cervical ectopia

    Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(8):447-449

    Summary

    Trabalhos Originais

    Frequency of human papillomavirus infection in women with cervical ectopia

    Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(8):447-449

    DOI 10.1590/S0100-72031999000800004

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    SUMMARY Purpose: the number of male sexual partners, age, precocious beginning of sexual activity, cigarette smoking and oral contraception were correlated with human papillomavirus (HPV) infection, as were cervical ectopia, although with conflicting results. The objective is to analyze a group of women with HPV infection and to verify the incidence of cervical ectopia. Methods: we have studied 471 women with Papanicolaou smears suggesting HPV infection (Schneider et al.'s criteria) and its relationship with cervical ectopia, beginning of sexual activity and the use of oral contraceptive. Results: of the total of cases, 182 (38.6%) had ectopia. Of these, 157 (86.3%) were 30 years old or less, compared to 47.8% of women without ectopia (p<0.001, chi² test). A percentage of 77.4 of cases with ectopia had the beginning of sexual activity before 18 years compared to 71.3% cases without ectopia. Among women with ectopia, 45.7% had taken the pill recently compared to 24.3% which had not (p<0.001, chi² test). Conclusions: it was concluded that the beginning of sexual activity was not correlated with ectopia. The prevalence of ectopia was more commom in women under 30 years and/or in use of oral contraceptive.

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  • Trabalhos Originais

    Cervical Cancer: Analysis of First Sexual Intercourse and Parity

    Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(9):555-559

    Summary

    Trabalhos Originais

    Cervical Cancer: Analysis of First Sexual Intercourse and Parity

    Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(9):555-559

    DOI 10.1590/S0100-72031999000900009

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    Purpose: high parity and/or young age at first sexual intercourse have been reported as risk factors for cervical cancer development. Actually, little research has been devoted to these risk factors. The aim of the present study was to analyze the parity and age at first sexual intercourse in women with invasive cervical cancer. Methods: we have retrospectively studied the age at first sexual intercourse and parity of 362 women with invasive cervical cancer diagnosed at the Outpatient Clinic of Oncological Gynecology of the "Faculdade de Medicina do Triângulo Mineiro" from 1978 to 1995. The cases were analyzed according to the date of diagnosis and divided into three groups: from 1978 to 1983 with 65 cases, from 1984 to 1989 with 127 cases and from 1990 to 1995 with 170 cases. Results: the results showed that high parity (4 or more births) diminished from the first to the third period (82, 67.3 and 63.8%, respectively) (p<0.02, chi² test). The first sexual intercourse before 18 years occurred respectively in 59.2, 54.5 and 55.5% of the patients (p, not significant). Conclusions: it was concluded that high parity seems to be related to invasive cervical cancer, although in recent years the parity decreased. The first sexual intercourse occurred before the age of 18 years in the patients of the three periods.

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  • Trabalhos Originais

    Human Papillomavirus Infection in Adolescents: Relation to Contraceptive Method, Pregnancy, Smoking, and Cytologic Findings

    Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(4):217-221

    Summary

    Trabalhos Originais

    Human Papillomavirus Infection in Adolescents: Relation to Contraceptive Method, Pregnancy, Smoking, and Cytologic Findings

    Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(4):217-221

    DOI 10.1590/S0100-72032001000400004

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    Purpose: to evaluate the influence of pregnancy, habit of smoking, and the contraceptive method in HPV infection and the frequency of cytologic findings in adolescent women with HPV infection. Methods: a total of 54,985 cytologic examinations of patients seen between July, 1993 and December, 1998 were retrospectively analyzed. Of this total, 6,498 (11.8%) examinations were from patients under 20 years old. Of the total of 6,498 cytologic examinations, 326 (5.9%) presented signs of HPV infection, with or without grade I cervical intraepithelial neoplasia (CIN). Patients with diagnosis of grade II and III CIN were excluded. The control group consisted of 333 patients paired by age, without cytological signs of HPV infection. Results: in adolescents, HPV infection was more frequent in oral contraceptive users (16.9% versus 13.8%, p<0.01) and in those who presented with clue cells in cytologic smears (22.4% versus 14.7%, p<0.001). The frequency of HPV infection in couples who used condom was 0% versus 2.1% in the control group (p<0.01). The difference in the number of pregnant women (41.1% versus 44.1%) and smokers (21.8% versus 16.5%) was not statistically significant. Conclusions: HPV infection is more frequent in adolescent women in use of oral contraceptive and with clue cells as cytologic finding. HPV infection did not occur in couples who used condom. Gestation and the habit of smoking did not influence the incidence of HPV infection.

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  • Trabalhos Originais

    Human papillomavirus infection in pregnancy: relationship with cytological findings

    Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(6):377-382

    Summary

    Trabalhos Originais

    Human papillomavirus infection in pregnancy: relationship with cytological findings

    Revista Brasileira de Ginecologia e Obstetrícia. 2001;23(6):377-382

    DOI 10.1590/S0100-72032001000600006

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    Purpose: to evaluate a group of pregnant women with human papillomavirus (HPV) infection, analyzing age, gestational age, number of gestations and cytological findings. Methods: in the period from July 1993 to December 1998, 245 pregnant patients seen in our service presented cytological alterations compatible with HPV infection, associated or not with cervical intraepithelial neoplasia (CIN) grade 1. Clinical data were related to age, gestational period (first or second half), number of gestations and cytological finding of Trichomonas vaginalis, Candida sp and clue cells. The control group consisted of 386 pregnant patients seen during the same period and without cytological signs of HPV infection. In the statistical analysis, chi² (chi-square) test was used with Yates correction and a significance level lower than 0.05. Results: HPV infection was more frequent among pregnant women younger than 20 years old (45.3% versus 28.2%, p<0.001). The most frequent cytological finding, among the pregnant women with HPV infection, was the presence of clue cells, compared to the controls (21.6% versus 12.4%, p<0.02). Clue cells were more frequent in pregnant women with HPV infection in the second half of gestation and older than 20 years (27% versus 12.2%, p<0,01). The difference regarding number of gestations was not significant. Conclusion: HPV infection was more frequent among pregnant women younger than 20 years old. Clue cells and HPV were the most frequent cytological findings in pregnant women older than 20 years and in the second half of gestation.

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