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  • Artigo de Revisão

    Brain sparing effect: from placental insufficiency to fetal circulatory adaptation

    Revista Brasileira de Ginecologia e Obstetrícia. 2008;30(7):366-371

    Summary

    Artigo de Revisão

    Brain sparing effect: from placental insufficiency to fetal circulatory adaptation

    Revista Brasileira de Ginecologia e Obstetrícia. 2008;30(7):366-371

    DOI 10.1590/S0100-72032008000700008

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    The application and development of obstetric Dopplervelocimetry provide a basis for the investigation of placental insufficiency and demonstrate the dynamic behavior of fetal circulation during hypoxia. In clinical practice, assessing hemodynamics in three vascular regions involved in pregnancy, namely the uterine, umbilical and middle cerebral arteries, has become routine. Roughly, the cerebral artery expresses the balance between uterine artery oxygen supply and umbilical artery oxygen uptake. Currently, when such balance is unfavorable, the fetal cardiac reserve is investigated by assessing the venous duct. However, determining and interpreting vascular resistance indexes is not an easy task. The starting point is to know the physiopathology of placental insufficiency and fetal circulatory adaptation through which Doppler confirmed its role in the assessment of fetal well-being.

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    Brain sparing effect: from placental insufficiency to fetal circulatory adaptation
  • Characteristics of b-hCG Regression Curves Following Complete Hydatidiform Mole

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):373-380

    Summary

    Characteristics of b-hCG Regression Curves Following Complete Hydatidiform Mole

    Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(6):373-380

    DOI 10.1590/S0100-72032000000600008

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    Purpose: to construct a b-human chorionic gonadotropin (b-hCG) regression curve following complete hydatidiform mole (CHM) of patients with spontaneous remission, and then compare it to that of CHM patients with gestational trophoblastic tumor (GTT). Also, to compare the b-hCG regression curve of CHM patients followed-up at the Service to the regression curve of other authors1-3. […]
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    Characteristics of b-hCG Regression Curves Following Complete Hydatidiform Mole
  • Trabalhos Originais

    Perinatal outcome of fetuses with congenital uropathies

    Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(10):725-730

    Summary

    Trabalhos Originais

    Perinatal outcome of fetuses with congenital uropathies

    Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(10):725-730

    DOI 10.1590/S0100-72032003001000005

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    PURPOSE: to evaluate the perinatal outcome of fetuses with congenital anomalies of the urinary tract. METHODS: we reviewed the perinatal outcome of 35 fetuses with congenital anomalies of the urinary tract. The following characteristics related to the uropathy were analyzed: type (hydronephrosis, dysplasia and renal agenesis), side of lesion (bilateral or unilateral), and level of the obstruction (high or low, in hydronephrosis). The perinatal outcome was evaluated according to these characteristics. The data were analyzed by the c² test and by the exact Fisher test. The level of significance was 0.05. RESULTS: the incidence of hydronephrosis was 68.6%. Half of the fetuses had unilateral hydronephrosis. Renal dysplasia occurred in 17.1% of the cases; 83.3% of these were bilateral and 16.7%, unilateral. The incidence of renal agenesis was 14.3%, all bilateral. The fetuses with dysplasia/agenesis had a 91% incidence of oligohydramnios, preterm birth, low birth weight, and death. In the group with bilateral disease the presence of oligohydramnios, preterm birth, low birth weight, death, urinary tract infections, and the need of hospitalization for a period greater than 7 days was significant when compared to the group with unilateral disease. The need of hospitalization for a period greater than 7 days in patients with low obstruction was significantly higher when compared to the patients with high obstruction. CONCLUSIONS: hydronephrosis, bilateral disease, and lower obstruction were the most frequent uropathies. The dysplasia/agenesis group had a worse prognosis when compared with the hydronephrosis group. Bilateral disease had a worse prognosis when compared with the unilateral disease group. In the low obstruction group, the need for a period of hospitalization greater than seven days was higher than in the high obstruction group.

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