Você pesquisou por y - Revista Brasileira de Ginecologia e Obstetrícia

PURPOSE: to correlate the presence of yeast from the Candida genus in the oral and vaginal cavity of women with and without vulvovaginal candidiasis (VVC), with secretor IgA levels (IgAs) present in the saliva. METHODS: among the 51 women included, 13 presented VVC and 38 were the Control Group. An amount of 2.0 mL of saliva without stimulation was collected from each patient, plus vaginal secretion using a swab, which was then immersed in 2.0 mL of physiological solution. Samples were inseminated in Sabouraud dextrose agar with chloramphenicol for isolation and counting of colonies, and the isolated ones, phenotypically identified. IgA has been quantified in the saliva of the women from both groups, by the ELISA technique. RESULTS: in the 13 patients with clinical and mycological diagnosis of VVC, the mean of Candida colony producing unities by milliliter of vaginal secretion (cpu/mL) was 52,723, and 23.8% of the patients presented colonization in the oral mucosa with lower amount of cup/mL (6,030). The levels of IgAs in saliva were lower in the group with VVC (DO mean: 0.3), as compared to the IgA levels of the Control Group (DO mean: 0.6). Eleven patients (37%) from the Control Group presented Candida colonization in the oral cavity, with a lower cup/mL mean, when compared to the VVC Group. The Control Group also presented a lower amount of cpu/mL (1,973) in the vaginal cavity, when compared to the VVC Group (52,942). CONCLUSIONS: these results have demonstrated that patients with clinical diagnosis of vaginal candidiasis presented a higher amount of Candida both in the vaginal and in the oral cavity, and presented lower levels of anti-Candida IgA in the saliva.