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You searched for:"Jurandir Piassi Passos"

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  • Case Report

    Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations

    Rev Bras Ginecol Obstet. 2021;43(4):323-328

    Summary

    Case Report

    Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations

    Rev Bras Ginecol Obstet. 2021;43(4):323-328

    DOI 10.1055/s-0041-1725054

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    Abstract

    Complete hydatidiform mole (CHM) is a rare type of pregnancy, in which 15 to 20% of the cases may develop into gestational trophoblastic neoplasia (GTN). The diagnostic of GTN must be done as early as possible through weekly surveillance of serum hCG after uterine evacuation.We report the case of 23-year-old primigravida, with CHM but without surveillance of hCG after uterine evacuation. Two months later, the patient presented to the emergency with vaginal bleeding and was referred to the Centro de Doenças Trofoblásticas do Hospital São Paulo. She was diagnosed with high risk GTN stage/score III:7 as per The International Federation of Gynecology and Obstetrics/World Health Organization (FIGO/WHO). The sonographic examination revealed enlarged uterus with a heterogeneous mass constituted of multiple large vessels invading and causing disarrangement of the myometrium. The patient evolved with progressive worsening of vaginal bleeding after chemotherapy with etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO) regimen. She underwent blood transfusion and embolization of uterine arteries due to severe vaginal hemorrhage episodes, with complete control of bleeding. The hCG reached a negative value after the third cycle, and there was a complete regression of the anomalous vascularization of the uterus as well as full recovery of the uterine anatomy. The treatment in a reference center was essential for the appropriate management, especially regarding the uterine arteries embolization trough percutaneous femoral

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    Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations
  • Original Article

    Open spina bifida: antenatal ultrasound findings and uterine contractions as predictors of the neonatal neuromotor outcome

    Rev Bras Ginecol Obstet. 2003;25(6):425-430

    Summary

    Original Article

    Open spina bifida: antenatal ultrasound findings and uterine contractions as predictors of the neonatal neuromotor outcome

    Rev Bras Ginecol Obstet. 2003;25(6):425-430

    DOI 10.1590/S0100-72032003000600007

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    PURPOSE: to determine whether prenatal sonographic findings and uterine contractions can predict neonatal motor outcome in fetuses with open spina bifida. METHODS: we evaluated retrospectively 53 fetuses with open spina bifida from 1993 to 2001. These fetuses were born and followed-up at the fetal medicine units of the Hospital São Paulo ("Universidade Federal de São Paulo") and the "Hospital Santa Joana". The influence of the alterations observed through ultrasound scan on neonatal muscular strength (macrocrania, microcrania, level of the spinal column opening, clubfoot and type of fetus position) was evaluated. The influence of uterine contractions on neonatal motor outcome was also evaluated. All deliveries were made through cesarian section. c² and Fisher tests were used for categorical comparisons. A p<0.05 was considered significant. RESULTS: Fifty-three cases of isolated open spina bifida were studied. Alterations of the cranial circumference size and the level of the lesion did not interfere in the neonatal motor perfomance. However, clubfoot and breech position showed to be predictors of an unfavorable neurological prognosis (p<0.05). Twenty-tree (43%) infants had clubfoot. Eighteen (78.3%) of these had abnormal leg movements. No infant in breech presentation (n=10) showed normal motor function. The presence of uterine contractions and the premature membrane rupture, observed in 13 fetuses (87%), were also linked to the alteration of neonatal muscular strength (p<0.05). CONCLUSION: clubfoot and breech presentation are ultrasonographic findings useful in predicting neurological neonatal outcome. Uterine contractions and premature membrane rupture are associated with poor motor neonatal outcome.

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