You searched for:"Edir Catafesta"
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Revista Brasileira de Ginecologia e Obstetrícia. 2005;27(11):661-664
DOI 10.1590/S0100-72032005001100005
PURPOSE: to compare the outcome of treatment in patients undergoing assisted reproductive technology (ART) cycles who donated eggs during their own ART treatment with the outcome of patients undergoing ART without egg donation. METHODS: we studied retrospectively the pregnancy and implantation rates of 50 patients who donated eggs during the course of their ART treatment (donor group), and the pregnancy and implantation rates of 50 patients who underwent ART cycles and kept all their eggs (non-donor group). between the years 2001-2003. The inclusion criteria used were as follows: age <35 years old, normal menstrual cycles, FSH<10 mIU/mL, first attempt of ART treatment and more than six mature oocytes retrieved. The results were analyzed statistically using the chi2 test. RESULTS: both groups were comparable in terms of age, indication, and duration of infertility. The mean age was 30.6 years for the donor group and 31.1 years for the non-donor group. All the patients of the donor group produced more than 6 eggs. From the donor group we collected 590 oocytes; 215 eggs were donated to recipients (36.5%) and 152 embryos were transferred. A total of 15 pregnancies were achieved (pregnancy rate per transfer: 30%); the implantation rate was 11.2% and there were 2 miscarriages (miscarriage rate: 13.3%). From the non-donor group, 545 oocytes were collected and 153 embryos were transferred. A total 17 pregnancies were achieved (pregnancy rate per transfer: 34%); the implantation rate was 14.3% and there were 3 miscarriages (miscarriage rate: 17.6%). The pregnancy and implantation rates were similar in both groups, and there were no significant statistical differences regarding the miscarriage rate (p>0.05). CONCLUSION: this study suggests that in patients who produce more than 6 oocytes, egg donation in the treatment cycle does not influence adversely the outcome of ART cycles and does not increase the miscarriage rate.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(10):603-605
DOI 10.1590/S0100-72031999001000007
The cryopreservation of embryos in late developing stages seems to present satisfactory results. With the purpose of better testing the embryos' survival, they were cryopreserved in the morula or blastocyst stage, thawed and left in culture for 24 hours so that their natural evolution could be observed. Amongst the frozen 2 blastocysts and 5 morulas, 4 morulas survived the thawing process, being transferred as blastocysts 24 hours later. The transfer was performed in a young patient, second marriage of a ten-year vasectomized man and resulted in twin pregnancy. Thawing morula embryos and the in vitro observation of their development resumption until the blastocyst stage give us an additional parameter in the quality evaluation of the embryo and probably an improvement in pregnancy rates.