You searched for:"Cídia Mazzoccato"
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Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(9):585-591
DOI 10.1590/S0100-72032002000900004
Purpose: to report 15 breast cancer cases associated with pregnancy and to compare to a control group with breast ductal infiltrating carcinoma, evaluating clinical staging, metastatic axillary lymph node involvement, histopathologic aspects related to nuclear grade, histology grade and estrogen and progesterone hormonal receptors. Method: a retrospective study of 15 cases of patients with breast cancer associated with pregnancy, attended at Mastology Department in the Woman Health Reference Center, Pérola Byington Hospital, São Paulo, was done between September 1996 and April 2001. The evaluation of clinical staging, time of diagnosis and involved axillary lymph nodes was the main study basis. Also age, parity, histologic type, applied treatment, histologic characteristics regarding nuclear grade and histologic grade and the presence of hormonal receptors in the tumors were analyzed. Results: we observed that 7 patients (46.7%) presented a locally advanced breast cancer (clinical stage IIIA and IIIB) and that 3 patients (20%) presented a disseminated disease at the moment of diagnosis. The patients presented on average 2.4 involved axillary lymph nodes and in only one patient the lymph nodes were free of disease (6.6%). Regarding time of diagnosis, 40% of the tumors were diagnosed during the lactational period, 46.7% during the second trimester and 13.3% during the third trimester. The pregnant patients were compared to a control group of non-pregnant patients in the same age range, all of them with infiltrating breast carcinoma, and clinical staging, axillary lymph node involvement, nuclear grade, histologic grade and estrogen and progesterone hormonal receptors were evaluated. There was a statistically significant difference (p=0.0022) regarding clinical staging and axillary lymph node involvement (p=0.0017), and no statistically significant difference as concerns the remaining parameters. Conclusion: breast cancer associated with pregnancy is a neoplasia with a bad prognosis. There is no difference when comparing pregnant patients with non-pregnant patients in the same age range, the advanced clinical staging at the moment of diagnosis being the determinant factor for survival.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(8):535-539
DOI 10.1590/S0100-72032002000800006
Purpose: to study the association between long-standing type 1 diabetes with bad glycemic control and breast inflammatory lesions which can simulate inflammatory carcinoma. Patients and Methods: eighteen patients were studied, retrospectively, in a mastology reference center from January 1998 to December 2001, presenting with breast inflammatory lesion with or without palpable mass. They were submitted to serum glucose and glycosylated hemoglobin determination, as well as image examination and histopathologic analysis, and diabetic mastopathy was diagnosed. Results: the patients' average age was 50.2 years, and all had insulin-dependent diabetes mellitus, with average disease time of 14.9 years. All patients, with no exception, had a bad glycemic control; the average blood glucose was 329.6 mg/dL and the glycosilated hemoglobin average was 9.7%. NPH insulin dose being applied per day was 37.2 units. Patients underwent a clinical treatment with antibiotics and control of the glycemic levels with NPH insulin and had resolution of the symptoms in about five weeks. Conclusion: the professionals involved in women health care must be aware of this inflammatory pathology of the breast and its benign characteristics to avoid unnecessary procedures sometimes with patient injury.