Você pesquisou por y?yr=2017 - Revista Brasileira de Ginecologia e Obstetrícia

8 articles
  • Editorial

    Future Perspectives for Uterine Cervical Cancer Treatment based on Integrative Genomic and Molecular Characterizations

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):147-148

    Summary

    Editorial

    Future Perspectives for Uterine Cervical Cancer Treatment based on Integrative Genomic and Molecular Characterizations

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):147-148

    DOI 10.1055/s-0037-1601399

    Views2
    Cervical cancer is the most frequent gynecologic malignancy in developing countries nowadays. Surgery is an effective treatment for the early stages of the disease. However, most patients are still diagnosed with inoperable locally advanced cervical cancer (LACC). In Brazil, the scenario is not different, and, according to Fundação Oncocentro de São Paulo (FOSP), from 2000 […]
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    Future Perspectives for Uterine Cervical Cancer Treatment based on Integrative Genomic and Molecular Characterizations
  • Original Article

    Ultrasonographic Evaluation of Uterine Involution in the Early Puerperium

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):149-154

    Summary

    Original Article

    Ultrasonographic Evaluation of Uterine Involution in the Early Puerperium

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):149-154

    DOI 10.1055/s-0037-1601418

    Views22

    Abstract

    Purpose

    Our aim was to describe the changes observed by ultrasonography in uterine dimensions during the early puerperium among women who experienced an uncomplicated puerperium. Additionally, the influence of parity, mode of delivery, breastfeeding and birth weight on uterine involution was evaluated.

    Methods

    Ninety-one patients underwent an ultrasound examination on days 1 (D1), 2 (D2) and 7 (D7) of the postpartum period. The longitudinal, anteroposterior and transverse uterine diameters were measured, and the uterine volume was calculated by the formula: longitudinal diameter (LD) X anteroposterior diameter (APD) X transverse diameter (TD) X 0.45. The thickness and length of the uterine cavity were also measured.

    Results

    The uterine volume and the LD, APD and TD decreased by 44.8%, 20.9%, 11.8% and 20.0% respectively. The uterine cavity thickness was reduced by 23%, and the length of the cavity was reduced by 27.2% on D7. Uterine involution was correlated inversely with parity when the day of the postpartum period was not taken into account (p= 0.01). However, when the uterine involution was correlated to parity separately, with D1, D2 or D3, no correlations were found. A significant difference occurred at D2, when it was found that the uterus had a smaller volume following cesarean section compared with vaginal delivery (p= 0.04). The high birth weight and breastfeeding were significantly related to uterine involution (p ≤ 0.01 and p= 0.04).

    Conclusion

    The sonographic evaluation of the uterus in the early puerperium should consider birth weight, breastfeeding and parity, as well as the delivery route on D2, to identify abnormalities related to uterine involution.

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    Ultrasonographic Evaluation of Uterine Involution in the Early Puerperium
  • Original Article

    High Blood Pressure during Pregnancy is not a Protective Factor for Preterm Infants with Very Low Birth Weight. A Case-Control Study

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):155-161

    Summary

    Original Article

    High Blood Pressure during Pregnancy is not a Protective Factor for Preterm Infants with Very Low Birth Weight. A Case-Control Study

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):155-161

    DOI 10.1055/s-0037-1601883

    Views6

    Abstract

    Objective

    To evaluate whether the presence of maternal blood pressure reduces the risks of morbidity, perinatal mortality and morbidity at 24 months of age in very low birth weight infants (VLBWIs) compared with a control group.

    Methods

    A retrospective, observational, case-control study. Total 49 VLBWIs were allocated to the study group, called the maternal arterial hypertension group (AHG), and matched with 44 in the control group (CG). The infants were assessed during hospitalization and at 12 and 24 months corrected age at a specialized clinic. For the assessment of growth, the World Health Organization (WHO) Anthro software (Geneva, 2006) was used, and for the psychomotor assessment, the Denver II test was used.

    Results

    In relation to the antenatal variables, the infants of the AHG had more centralized circulation assessed by Doppler, received more corticosteroids and magnesium sulfate, and were born by cesarean section more frequently. In terms of the postnatal and in-hospital outcomes, the AHG had a higher gestational age at birth (30.7 versus 29.6 weeks) and a lower frequency of 5-minute Apgar scores of less than 7 (26.5% versus 52.3%). The CG had a higher rate of pulmonary dysplasia (30.2% versus 8.3%). There were no differences in terms of hospital mortality, complications, somatic growth and functional problems at 24 months of corrected age.

    Conclusion

    The presence of maternal hypertension, especially preeclampsia, was not a protective factor against morbidity, mortality and evolution in VLBWIs aged up to 24 months. Therefore, the clinical practice should be focused on prolonging the pregnancy for as long as possible in these conditions as well.

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  • Original Article

    Antral Follicles Count and Anti-Müllerian Hormone Levels after Gonadotoxic Chemotherapy in Patients with Breast Cancer: Cohort Study

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):162-168

    Summary

    Original Article

    Antral Follicles Count and Anti-Müllerian Hormone Levels after Gonadotoxic Chemotherapy in Patients with Breast Cancer: Cohort Study

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):162-168

    DOI 10.1055/s-0037-1601438

    Views6

    Abstract

    Aim

    To assess ovarian reserve (OVR) by means of follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and antral follicle count (AFC) measurement in eumenorrheic women with breast cancer, exposed to gonadotoxic chemotherapy.

    Method

    Fifty-two women (35.3 ± 3.8 years old) with breast cancer and undergoing cyclophosphamide-containing chemotherapy were enrolled. The assessment was performed before chemotherapy (T1) and after 2 (T2) and 6 months (T3).

    Results

    Six months after chemotherapy, the prevalence of regular cycles was 60%. Anti-Müllerian hormone decreased down to undetectable levels at T2 and T3 (T1: 2.53 [1.00–5.31]; T2 < 0.08; T3: < 0.08 [< 0.08–1.07] ng/mL), (p< 0.0001). Antral follicle count was 11 [8.0–13.5] follicles at T1 and lower at T2 (5.50 [3.75–8.0] and T3 (5.0 [2.5–7.0]) (p< 0.0001). In patients who remained with regular cycles during chemotherapy or resumed normal menses, FSH and estradiol levels remained unchanged.

    Conclusion

    Anti-Müllerian hormone and AFC are useful as markers of OVR decline in women exposed to chemotherapy. Follicle-stimulating hormone is only adequate in women who become amenorrheic.

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    Antral Follicles Count and Anti-Müllerian Hormone Levels after Gonadotoxic Chemotherapy in Patients with Breast Cancer: Cohort Study
  • Original Article

    Can the Pessary Use Modify the Vaginal Microbiological Flora? A Cross-sectional Study

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):169-174

    Summary

    Original Article

    Can the Pessary Use Modify the Vaginal Microbiological Flora? A Cross-sectional Study

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):169-174

    DOI 10.1055/s-0037-1601437

    Views3

    Abstract

    Introduction

    Vaginal pessary is used as a conservative treatment for pelvic organ prolapse (POP). Some studies have shown that common complaints of its use may include vaginal discomfort and increased vaginal discharge. Scant information is available about the microflora status after using this device.

    Objective

    To determine if the usage of vaginal pessary can interfere with the vaginal environment.

    Methods

    A cross-sectional study was performed from March of 2014 to July of 2015 including 90 women with POP. The study group was composed of 45 women users of vaginal pessary and 45 nom-users. All enrolled women answered a standardized questionnaire and were subjected to a gynecological exam to collect vaginal samples for microbiological evaluation under optic microscopy. Clinical and microbiological data were compared between study and control groups.

    Results

    Vaginal discharge was confirmed in 84% of the study group versus 62.2% in the control group (p< 0.01); itching was reported in 20 and 2.2%, respectively (p< .05); genital ulcers were only found in the pessary group (20%). There was no difference with regard to the type of vaginal flora. Bacterial vaginosis was prevalent in the study group (31.1% study group versus 22.2% control group), (p=.34).

    Conclusion

    Women using vaginal pessaries for POP treatment presented more vaginal discharge, itching and genital ulcers than non-users.

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  • Original Article

    Influence of Body Image in Women Undergoing Treatment for Breast Cancer

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):175-183

    Summary

    Original Article

    Influence of Body Image in Women Undergoing Treatment for Breast Cancer

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):175-183

    DOI 10.1055/s-0037-1601453

    Views17

    Abstract

    Objective

    The objective of this study was to investigate the self-esteem of women with and without breast cancer regarding their body image.

    Methods

    A quantitative, case-control study in which 90 women with breast cancer were evaluated in the case group, and 77 women without breast cancer in the control group. For data collection, the body satisfaction scale (BSS), a scale adapted and validated in Brazil, and the Rosenberg self-esteem questionnaire were used. For the statistical analysis of the data, the Statistical Package for the Social Sciences software (IBM-SPSS, Chicago, Il, US), version 16.0 was used.

    Results

    Compared with the women without breast cancer, those with breast cancer were more dissatisfied with body image related to appearance. Women undergoing neoadjuvant chemotherapy were more dissatisfied with their appearance compared with those with cancer who were not undergoing this treatment. Mastectomy also accounted for more dissatisfaction concerning appearance among women who underwent the procedure compared with the women who were submitted to breast-conserving therapy.

    Conclusion

    Women with breast cancer were more dissatisfied with their body image compared with those without breast cancer, particularly following mastectomy or during chemotherapy. The self-esteem was found to be negatively affected in patients who were dissatisfied with their body image.

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  • Original Article

    A Model for the Management of Female Sexual Dysfunctions

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):184-194

    Summary

    Original Article

    A Model for the Management of Female Sexual Dysfunctions

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):184-194

    DOI 10.1055/s-0037-1601435

    Views32

    Abstract

    Introduction

    Sexual pleasure is fundamental for the maintenance of health and well-being, but it may be adversely affected by medical and psychosocial conditions. Many patients only feel that their health is fully restored after they resume normal sexual activities. Any discussion of sexuality in a doctor's office is typically limited, mainly because of a lack of models or protocols available to guide the discussion of the topic.

    Objectives

    To present a model designed to guide gynecologists in the management of female sexual complaints.

    Methods

    This study presents a protocol used to assess women's sexual problems. A semi-structured interview is used to assess sexual function, and the teaching, orienting and permitting (TOP) intervention model that was designed to guide gynecologists in the management of sexual complaints.

    Results

    The use of protocols may facilitate the discussion of sexual issues in gynecological settings, and has the potential to provide an effective approach to the complex aspects of sexual dysfunction in women. The TOP model has three phases: teaching the sexual response, in which the gynecologist explains the physiology of the female sexual response, and focuses on the three main phases thereof (desire, excitement and orgasm); orienting a woman toward sexual health, in which sexual education is used to provide information on the concept and healthy experience of sexuality; and permitting and stimulating sexual pleasure, which is based on the assumption that sexual pleasure is an individual right and is important for the physical and emotional well-being.

    Conclusion

    The use of protocols may provide an effective approach to deal with female sexual dysfunction in gynecological offices.

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    A Model for the Management of Female Sexual Dysfunctions
  • Case Report

    Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):195-198

    Summary

    Case Report

    Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome

    Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(4):195-198

    DOI 10.1055/s-0037-1600124

    Views6

    Abstract

    A pregnancy complicated by typical hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is reported. At 20 weeks of gestation, a case of HUS was diagnosed, with Shiga toxin-producing Escherichia coli identified. Plasmapheresis allowed continuation of the pregnancy for 5 weeks. Superimposed preeclampsia and HELLP syndrome were diagnosed after the establishment of nephrotic range proteinuria, hypertension and recurrence of hemolysis. This is a singular case, as it demonstrates that HELLP syndrome can superimpose upon HUS, a fact that can impact future research on reproductive immunology. It also reminds clinicians that the overlapping of clinical and laboratory findings in HELLP syndrome makes the diagnosis of other thrombotic microangiopathies during pregnancy a clinical challenge.

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