Você pesquisou por y?yr=2000 - Revista Brasileira de Ginecologia e Obstetrícia
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):101-106
DOI 10.1590/S0100-72032000000200007
Purpose: to evaluate the prevalence of anticardiolipin antibody in women with stillbirth. Patients and Methods: this was a cross-sectional study performed from May 1998 to September 1999 at the Maternity of the University of Campinas and at the Hospital and Maternity Leonor Mendes de Barros, in Brazil, which evaluated 109 pregnant women hospitalized with the diagnosis of intrauterine fetal death and gestational age of 20 or more weeks. These women underwent some laboratory examinations to identify the cause of fetal death, including anticardiolipin antibody evaluation performed through the determination of IgG and IgM serum levels. IgG and IgM results are expressed as GPL and MPL units, respectively, and, in both cases, results above 10 units are considered positive. The statistical procedures used were the mean and standard deviation estimates, Student's t test, Fisher test and chi². Results: the prevalence of anticardiolipin positivity was 18.3%. The women were predominantly young, with a mean age around 27 years. The main identified causes of fetal death were: hypertension (26.1%), hemorrhage during the third trimester (9.9%) and fetal malformation (8.1%). One third of the cases had no identified causes of fetal death. However, considering the 20 positive cases for anticardiolipin antibody, the proportion of unidentified causes decreased to 29%. Conclusions: it is important to investigate the presence of anticardiolipin antibodies among women with intrauterine fetal death with the purpose of clarifying the causes of stillbirth. If the diagnosis of antiphospholipid syndrome is confirmed, it is necessary to counsel and treat these women regarding future pregnancies.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):101-106
DOI 10.1590/S0100-72032000000200007
Purpose: to evaluate the prevalence of anticardiolipin antibody in women with stillbirth. Patients and Methods: this was a cross-sectional study performed from May 1998 to September 1999 at the Maternity of the University of Campinas and at the Hospital and Maternity Leonor Mendes de Barros, in Brazil, which evaluated 109 pregnant women hospitalized with the diagnosis of intrauterine fetal death and gestational age of 20 or more weeks. These women underwent some laboratory examinations to identify the cause of fetal death, including anticardiolipin antibody evaluation performed through the determination of IgG and IgM serum levels. IgG and IgM results are expressed as GPL and MPL units, respectively, and, in both cases, results above 10 units are considered positive. The statistical procedures used were the mean and standard deviation estimates, Student's t test, Fisher test and chi². Results: the prevalence of anticardiolipin positivity was 18.3%. The women were predominantly young, with a mean age around 27 years. The main identified causes of fetal death were: hypertension (26.1%), hemorrhage during the third trimester (9.9%) and fetal malformation (8.1%). One third of the cases had no identified causes of fetal death. However, considering the 20 positive cases for anticardiolipin antibody, the proportion of unidentified causes decreased to 29%. Conclusions: it is important to investigate the presence of anticardiolipin antibodies among women with intrauterine fetal death with the purpose of clarifying the causes of stillbirth. If the diagnosis of antiphospholipid syndrome is confirmed, it is necessary to counsel and treat these women regarding future pregnancies.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):107-111
DOI 10.1590/S0100-72032000000200008
Purpose: the aim of the present work was to study the chronic action of the antiemetic domperidone on the pregnancy of albino rats. Methods: fifty albino, pregnant Wistar rats were randomly allocated to five groups: GI (control I) = intact rats; GII (control II) = rats receiving the drug vehicle (distilled water) by gavage at the same schedule of the experimental groups; rats in groups GIII, GIV and GV were treated with domperidone by gavage, 2, 6 and 12 mg/kg per day, respectively, divided into 4 daily doses, always in 1 ml of distilled water, from time zero up to the 20th day of pregnancy. The evolution of body weight gain was followed throughout and the animals were sacrificed at term (20th day) by deep ether anesthesia. Number of fetuses, placenta and implantation sites, placenta and fetus weight, fetal malformations and maternal and fetal mortality were evaluated. Results: we observed only intrauterine fetal mortality with 14, 26 and 32 in 74, 60 and 57 newborns of the groups III, IV and V, respectively. Conclusion: though the results of animal experimentation cannot directly be transposed to human conditions, this paper calls attention to the need for a safe judgement when prescribing domperidone to a first-trimester pregnant patient in order to reduce her emetic crises.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):107-111
DOI 10.1590/S0100-72032000000200008
Purpose: the aim of the present work was to study the chronic action of the antiemetic domperidone on the pregnancy of albino rats. Methods: fifty albino, pregnant Wistar rats were randomly allocated to five groups: GI (control I) = intact rats; GII (control II) = rats receiving the drug vehicle (distilled water) by gavage at the same schedule of the experimental groups; rats in groups GIII, GIV and GV were treated with domperidone by gavage, 2, 6 and 12 mg/kg per day, respectively, divided into 4 daily doses, always in 1 ml of distilled water, from time zero up to the 20th day of pregnancy. The evolution of body weight gain was followed throughout and the animals were sacrificed at term (20th day) by deep ether anesthesia. Number of fetuses, placenta and implantation sites, placenta and fetus weight, fetal malformations and maternal and fetal mortality were evaluated. Results: we observed only intrauterine fetal mortality with 14, 26 and 32 in 74, 60 and 57 newborns of the groups III, IV and V, respectively. Conclusion: though the results of animal experimentation cannot directly be transposed to human conditions, this paper calls attention to the need for a safe judgement when prescribing domperidone to a first-trimester pregnant patient in order to reduce her emetic crises.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):113-116
DOI 10.1590/S0100-72032000000200009
Takayasu's arteritis is an idiopathic occlusive inflammation of the aorta and its major branches. The disease shows a striking predilection for young women and thus is occasionally associated with pregnancy. The authors describe a case of a pregnant patient with Takayasu's arteritis. The pregnancy was accompanied by a multidisciplinary group in a satisfactory way. There was only one hospitalization due to an exacerbation of the symptoms during the 32nd week of gestation, controlled by medical treatment. A vaginal delivery occurred at 37 weeks. A live infant weighing 2,750 g was delivered and the patient had an uncomplicated course.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):113-116
DOI 10.1590/S0100-72032000000200009
Takayasu's arteritis is an idiopathic occlusive inflammation of the aorta and its major branches. The disease shows a striking predilection for young women and thus is occasionally associated with pregnancy. The authors describe a case of a pregnant patient with Takayasu's arteritis. The pregnancy was accompanied by a multidisciplinary group in a satisfactory way. There was only one hospitalization due to an exacerbation of the symptoms during the 32nd week of gestation, controlled by medical treatment. A vaginal delivery occurred at 37 weeks. A live infant weighing 2,750 g was delivered and the patient had an uncomplicated course.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):117-117
DOI 10.1590/S0100-72032000000200010
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):117-117
DOI 10.1590/S0100-72032000000200010
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):117-117
DOI 10.1590/S0100-72032000000200011
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):117-117
DOI 10.1590/S0100-72032000000200011
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):118-118
DOI 10.1590/S0100-72032000000200012
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):118-118
DOI 10.1590/S0100-72032000000200012
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):118-118
DOI 10.1590/S0100-72032000000200013
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):118-118
DOI 10.1590/S0100-72032000000200013
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):119-119
DOI 10.1590/S0100-72032000000200014
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 2000;22(2):119-119
DOI 10.1590/S0100-72032000000200014