Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):105-108
DOI 10.1590/S0100-72031999000200008
Purpose: to evaluate the effects of acetaminophen on the pregnancy of female albino rats. Methods: forty pregnant rats were separated into four groups. All the animals received daily by gavage 1 ml of acetaminophen solution from the first day (day zero) until the 20th day of pregnancy: group I - only distilled water (control); groups II, III and IV, respectively, 125, 500 and 1,500 mg/kg body weight of acetaminophen dissolved in distilled water. The animals were weighed on days 0, 7, 15 and 20 of pregnancy. Results: our results showed that the rats that received the medication presented a reduction in weight when compared to the control group. The incidence of reabsorption of the embryos was 2.0, 3.5 and 7.0 times higher than in the control, in groups II, III and IV, respectively. Groups GII and GIV showed a clear reduction in the weight of the concepts. In GIV there was a 50% reduction in weight increase of fetuses and placentas when compared to the control, and 15.7% of external malformations were also found. Conclusions: the continuous use of acetaminophen should be avoided at doses higher than 70 mg/kg per during pregnancy.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):109-111
DOI 10.1590/S0100-72031999000200009
A rare case of bilateral benign phyllode tumor of the breast with fast growth during pregnancy and reaching great dimensions is presented. The patient was submitted to bilateral mastectomy on the 20th week of pregnancy. She had a good postoperative evolution and vaginal delivery occurred on the 40th week, when a healthy boy was born. The clinical and surgical features, the pathologic findings and the evolution of pregnancy are discussed.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):113-115
DOI 10.1590/S0100-72031999000200010
The authors report a rare case of dermatomyositis diagnosed at the Mastology Sector of the Division of Gynecology of the Federal University of São Paulo - Escola Paulista de Medicina, which caused breast deformity due to formation of bilateral dystrophic calcifications.
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):117-117
DOI 10.1590/S0100-72031999000200011
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):117-117
DOI 10.1590/S0100-72031999000200012
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):118-118
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):118-118
DOI 10.1590/S0100-72031999000200014
Summary
Revista Brasileira de Ginecologia e Obstetrícia. 1999;21(2):66-66